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The map label for this gene is sotB [H]

Identifier: 167622703

GI number: 167622703

Start: 945475

End: 946662

Strand: Reverse

Name: sotB [H]

Synonym: Shal_0763

Alternate gene names: 167622703

Gene position: 946662-945475 (Counterclockwise)

Preceding gene: 167622704

Following gene: 167622699

Centisome position: 18.11

GC content: 52.19

Gene sequence:

>1188_bases
ATGAAACCAGACCCGATGAAACAGCGCCTTCTCAATTGGGCACCAGTATGGTTACTGGCTCTGACCGCCTTCGTTTTTGT
CTCAACTGAATTTGTCCCGGTAGGCATCTTAGCCGCCCTCGGCCAAAGCTTTAATATGAGCGCCGTCGCTGTGGGTCCCA
TGCTTACCGTGTATGCCGCCGTAGTTGCGCTGGCATCTCTGCCTGCAGTGCTATTGTTTGCCCGCTTTGAGCGTAAAAAG
CTGCTGTTAGGAATAATGGCGGTGTTCATCATCAGCCATGGGATCTGCGTCTGGGCGCCGAGTTACGACATTCTACTATC
GGGCCGCATCGGTATCGCCTTAACGCACGCATTATTTTGGGCGATCGCCCCTGCTTTAGTCGTACGGTTAGCCCCTGAGG
GACAAGGCGCCAAAGCCTTAAGTATCTTCGCTACTGGCTGCGTACTAGCGCTGGTATTGGGCATTCCACTCGGACGAGTA
ATAGGCCAATTAATCGGTTGGCGTAGCATTTTTGCCTTAATCGGCTTGCTCACATTCGCCATGATGTTACTGCTGTGGCG
CGGTCTTCCTAATTTACCCGCGACCCATGGCGGCAGTTGGCGCAGCCTGCCCGCATTAGCACGTAACAAAGCCCTGCTCT
GGTTGTATCTGTTAACCATGACCCTCGTTACCGCTCACTACAGTGTTTACACTTATCTGGAGCCACTGCTGCAAGAGCAT
TTTGGTTACTCGGCGAATATCACCACCATGATCTTGCTGACTTTTGGTGGGGCAGGCTTAATTGGTAGTGCGCTATTTAG
TCGCTATCAGGCGCGTAATGCTCAACAGTTGCTGATGATCGCGATAGCATCGCTCGGCACTTGCATGGCGATATTACCGT
TTATCGCGAGCCAAATATGGCTATTGCTGCCACTGTGTATTTTATGGGGCACTGGTATGATGTTGATGTGTCTGTCGCTG
CAATCTAAGGCGTTAAAACTCGCACCCGATGCCACCGATGTGGCAATGGCTATCTACTCGGGTCTATTTAACGTGGGGAT
TGGTAGCGGCGCCCTGCTTGGCAGTATCGTTGCGGCGCAATATGGCGTCGTTCAAAATGGCACCTGGGCAACCCTATTGG
TACTACTGGCTTTAGTGCCGCTGTTCTTTTTACTGCAAGCACGCCGAGCAACACTGGCGGTTCACTAA

Upstream 100 bases:

>100_bases
ACAAATCGCACATCCCACAACCTGCACCTTCACCTCCACTCTCGCCAAAAATCTCGTTTGGGCGTAGACTTGCCGCCCTT
TCAATTTTGATTTAGACCCA

Downstream 100 bases:

>100_bases
TACCCTTTAATCTATTTACGCTGTGGCCATTTTATAAGCCAGAATGTATTAAGCCACTGTGCATTAATCCACAATGCATT
AAATAATGTTGGCTGCGAAG

Product: sugar efflux transporter

Products: arabinose [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MKPDPMKQRLLNWAPVWLLALTAFVFVSTEFVPVGILAALGQSFNMSAVAVGPMLTVYAAVVALASLPAVLLFARFERKK
LLLGIMAVFIISHGICVWAPSYDILLSGRIGIALTHALFWAIAPALVVRLAPEGQGAKALSIFATGCVLALVLGIPLGRV
IGQLIGWRSIFALIGLLTFAMMLLLWRGLPNLPATHGGSWRSLPALARNKALLWLYLLTMTLVTAHYSVYTYLEPLLQEH
FGYSANITTMILLTFGGAGLIGSALFSRYQARNAQQLLMIAIASLGTCMAILPFIASQIWLLLPLCILWGTGMMLMCLSL
QSKALKLAPDATDVAMAIYSGLFNVGIGSGALLGSIVAAQYGVVQNGTWATLLVLLALVPLFFLLQARRATLAVH

Sequences:

>Translated_395_residues
MKPDPMKQRLLNWAPVWLLALTAFVFVSTEFVPVGILAALGQSFNMSAVAVGPMLTVYAAVVALASLPAVLLFARFERKK
LLLGIMAVFIISHGICVWAPSYDILLSGRIGIALTHALFWAIAPALVVRLAPEGQGAKALSIFATGCVLALVLGIPLGRV
IGQLIGWRSIFALIGLLTFAMMLLLWRGLPNLPATHGGSWRSLPALARNKALLWLYLLTMTLVTAHYSVYTYLEPLLQEH
FGYSANITTMILLTFGGAGLIGSALFSRYQARNAQQLLMIAIASLGTCMAILPFIASQIWLLLPLCILWGTGMMLMCLSL
QSKALKLAPDATDVAMAIYSGLFNVGIGSGALLGSIVAAQYGVVQNGTWATLLVLLALVPLFFLLQARRATLAVH
>Mature_395_residues
MKPDPMKQRLLNWAPVWLLALTAFVFVSTEFVPVGILAALGQSFNMSAVAVGPMLTVYAAVVALASLPAVLLFARFERKK
LLLGIMAVFIISHGICVWAPSYDILLSGRIGIALTHALFWAIAPALVVRLAPEGQGAKALSIFATGCVLALVLGIPLGRV
IGQLIGWRSIFALIGLLTFAMMLLLWRGLPNLPATHGGSWRSLPALARNKALLWLYLLTMTLVTAHYSVYTYLEPLLQEH
FGYSANITTMILLTFGGAGLIGSALFSRYQARNAQQLLMIAIASLGTCMAILPFIASQIWLLLPLCILWGTGMMLMCLSL
QSKALKLAPDATDVAMAIYSGLFNVGIGSGALLGSIVAAQYGVVQNGTWATLLVLLALVPLFFLLQARRATLAVH

Specific function: Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites [H]

COG id: COG2814

COG function: function code G; Arabinose efflux permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family [H]

Homologues:

Organism=Escherichia coli, GI1787808, Length=354, Percent_Identity=49.1525423728814, Blast_Score=279, Evalue=2e-76,
Organism=Escherichia coli, GI145693198, Length=343, Percent_Identity=25.3644314868805, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787947, Length=338, Percent_Identity=26.9230769230769, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1786595, Length=255, Percent_Identity=26.6666666666667, Blast_Score=86, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 42389; Mature: 42389

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPDPMKQRLLNWAPVWLLALTAFVFVSTEFVPVGILAALGQSFNMSAVAVGPMLTVYAA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
VVALASLPAVLLFARFERKKLLLGIMAVFIISHGICVWAPSYDILLSGRIGIALTHALFW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEECCHHHHHHHHHHH
AIAPALVVRLAPEGQGAKALSIFATGCVLALVLGIPLGRVIGQLIGWRSIFALIGLLTFA
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
MMLLLWRGLPNLPATHGGSWRSLPALARNKALLWLYLLTMTLVTAHYSVYTYLEPLLQEH
HHHHHHCCCCCCCCCCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGYSANITTMILLTFGGAGLIGSALFSRYQARNAQQLLMIAIASLGTCMAILPFIASQIW
CCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLPLCILWGTGMMLMCLSLQSKALKLAPDATDVAMAIYSGLFNVGIGSGALLGSIVAAQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
YGVVQNGTWATLLVLLALVPLFFLLQARRATLAVH
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKPDPMKQRLLNWAPVWLLALTAFVFVSTEFVPVGILAALGQSFNMSAVAVGPMLTVYAA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
VVALASLPAVLLFARFERKKLLLGIMAVFIISHGICVWAPSYDILLSGRIGIALTHALFW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEECCHHHHHHHHHHH
AIAPALVVRLAPEGQGAKALSIFATGCVLALVLGIPLGRVIGQLIGWRSIFALIGLLTFA
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
MMLLLWRGLPNLPATHGGSWRSLPALARNKALLWLYLLTMTLVTAHYSVYTYLEPLLQEH
HHHHHHCCCCCCCCCCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGYSANITTMILLTFGGAGLIGSALFSRYQARNAQQLLMIAIASLGTCMAILPFIASQIW
CCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLPLCILWGTGMMLMCLSLQSKALKLAPDATDVAMAIYSGLFNVGIGSGALLGSIVAAQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
YGVVQNGTWATLLVLLALVPLFFLLQARRATLAVH
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: arabinose [Cytoplasm]; Proton [Periplasm] [C]

Specific reaction: arabinose [Cytoplasm] + Proton [Periplasm] = arabinose [Periplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA