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The map label for this gene is argF [H]

Identifier: 167622627

GI number: 167622627

Start: 846809

End: 847813

Strand: Reverse

Name: argF [H]

Synonym: Shal_0687

Alternate gene names: 167622627

Gene position: 847813-846809 (Counterclockwise)

Preceding gene: 167622628

Following gene: 167622626

Centisome position: 16.22

GC content: 43.18

Gene sequence:

>1005_bases
ATGGCTTTTAACTTAAAAAATCGTAATTTTCTAAAATTATTAGACTATACACCTGCTGAAATCATGTTCCTGCTTAATTT
ATCAATTGATCTTAAAAAAGCCAAGTACGCTGGCATTGAGCAAAAAAAACTAGCGGGTAAAAACATAGCACTAATTTTTG
AAAAATCCTCAACCCGTACCCGCTGCGCTTTTGAAGTAGCAGCTTTCGATCAAGGTGCATTCGTGACGTATCTTGGCCCA
AGCGGTTCGCAAATCGGCCATAAAGAATCCATGAAAGATACCGCCCGAGTGTTAGGCCGTATGTATGATGGCATCGAATA
CCGTGGTTTTGGTCAGGAAATCGTAGAAGAGTTAGGTCAATATGCAGGCGTTCCTGTTTGGAACGGTTTGACTGATGAAT
TCCACCCAACTCAGATCTTGGCTGACTTTATGACCATGATGGAGCATTTACCAGGCACTCCGTTAAACAAGATCAAGTTT
GCCTATATGGGAGATGCACGCTTCAACATGGGGAATTCACTGATGGTAGGTGCCGCAAAAATGGGCATGGAGATCCACTT
AGTAGCGCCTAAGGCATACTGGCCAGATGAGAAGTTAGTCAGGGAATGTCTTGATATAGCAGAAACAACCGGTGCCAAGA
TTGTGCTAACCGAAAATGTTGAAACCGGTGTTGCAGGTATGGACTTTATCTACACCGACGTTTGGGTCTCTATGGGTGAG
GCAAAAGAAGCATGGGCTGAGCGTATTCGCGTAATGACACCTTATCAGGTGAATATGGACGTGATTAAGCAGACAGGTAA
TCCTCAAGTTAAGTTTATGCACTGCTTACCCGCATTCCATGATGAGCATACCACTATGGGTAAAGAGATCGAACAAACCT
ATAACATGAAAGGCTTAGAAGTCACCGATGACGTGTTTGAATCCCATCATTCAATCGTATTTGATGAAGCTGAAAATCGC
ATGCACACCATTAAAGCTGTGATGGTGGCCACATTAGGGGCTTAA

Upstream 100 bases:

>100_bases
TAACATCAAGCTTTAAAGTGCGTTAAATTTCATCTCAGTTAATCCAGCAGACCATTTCTCTGCTGGAATTAAAATCTCAA
TATTATTAAGGATATTAATC

Downstream 100 bases:

>100_bases
TTCACTAAGGCGCTAAACAAGAGTCAATTTTAGCGCCATTGCTAACATATGTTTAGACGTAATAGAGCGTAAAGCAGGTT
CGGGCTCCTTAACTCCGCAT

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MAFNLKNRNFLKLLDYTPAEIMFLLNLSIDLKKAKYAGIEQKKLAGKNIALIFEKSSTRTRCAFEVAAFDQGAFVTYLGP
SGSQIGHKESMKDTARVLGRMYDGIEYRGFGQEIVEELGQYAGVPVWNGLTDEFHPTQILADFMTMMEHLPGTPLNKIKF
AYMGDARFNMGNSLMVGAAKMGMEIHLVAPKAYWPDEKLVRECLDIAETTGAKIVLTENVETGVAGMDFIYTDVWVSMGE
AKEAWAERIRVMTPYQVNMDVIKQTGNPQVKFMHCLPAFHDEHTTMGKEIEQTYNMKGLEVTDDVFESHHSIVFDEAENR
MHTIKAVMVATLGA

Sequences:

>Translated_334_residues
MAFNLKNRNFLKLLDYTPAEIMFLLNLSIDLKKAKYAGIEQKKLAGKNIALIFEKSSTRTRCAFEVAAFDQGAFVTYLGP
SGSQIGHKESMKDTARVLGRMYDGIEYRGFGQEIVEELGQYAGVPVWNGLTDEFHPTQILADFMTMMEHLPGTPLNKIKF
AYMGDARFNMGNSLMVGAAKMGMEIHLVAPKAYWPDEKLVRECLDIAETTGAKIVLTENVETGVAGMDFIYTDVWVSMGE
AKEAWAERIRVMTPYQVNMDVIKQTGNPQVKFMHCLPAFHDEHTTMGKEIEQTYNMKGLEVTDDVFESHHSIVFDEAENR
MHTIKAVMVATLGA
>Mature_333_residues
AFNLKNRNFLKLLDYTPAEIMFLLNLSIDLKKAKYAGIEQKKLAGKNIALIFEKSSTRTRCAFEVAAFDQGAFVTYLGPS
GSQIGHKESMKDTARVLGRMYDGIEYRGFGQEIVEELGQYAGVPVWNGLTDEFHPTQILADFMTMMEHLPGTPLNKIKFA
YMGDARFNMGNSLMVGAAKMGMEIHLVAPKAYWPDEKLVRECLDIAETTGAKIVLTENVETGVAGMDFIYTDVWVSMGEA
KEAWAERIRVMTPYQVNMDVIKQTGNPQVKFMHCLPAFHDEHTTMGKEIEQTYNMKGLEVTDDVFESHHSIVFDEAENRM
HTIKAVMVATLGA

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=329, Percent_Identity=37.3860182370821, Blast_Score=200, Evalue=2e-51,
Organism=Escherichia coli, GI1786469, Length=331, Percent_Identity=67.97583081571, Blast_Score=475, Evalue=1e-135,
Organism=Escherichia coli, GI1790703, Length=327, Percent_Identity=67.2782874617737, Blast_Score=471, Evalue=1e-134,
Organism=Escherichia coli, GI48994908, Length=373, Percent_Identity=23.0563002680965, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI2367364, Length=237, Percent_Identity=28.2700421940928, Blast_Score=63, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322373, Length=289, Percent_Identity=35.6401384083045, Blast_Score=160, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 37522; Mature: 37391

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
6.3 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
6.0 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFNLKNRNFLKLLDYTPAEIMFLLNLSIDLKKAKYAGIEQKKLAGKNIALIFEKSSTRT
CEECCCCCCEEEEECCCHHHEEEEEECCEEECHHHHCCCHHHHHCCCCEEEEEECCCCCC
RCAFEVAAFDQGAFVTYLGPSGSQIGHKESMKDTARVLGRMYDGIEYRGFGQEIVEELGQ
EEEEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
YAGVPVWNGLTDEFHPTQILADFMTMMEHLPGTPLNKIKFAYMGDARFNMGNSLMVGAAK
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHEEEEEECCCEECCCCCEEEEHHH
MGMEIHLVAPKAYWPDEKLVRECLDIAETTGAKIVLTENVETGVAGMDFIYTDVWVSMGE
CCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCC
AKEAWAERIRVMTPYQVNMDVIKQTGNPQVKFMHCLPAFHDEHTTMGKEIEQTYNMKGLE
HHHHHHHHHEECCCCCCCHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCE
VTDDVFESHHSIVFDEAENRMHTIKAVMVATLGA
ECHHHHHCCCCEEEECHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AFNLKNRNFLKLLDYTPAEIMFLLNLSIDLKKAKYAGIEQKKLAGKNIALIFEKSSTRT
EECCCCCCEEEEECCCHHHEEEEEECCEEECHHHHCCCHHHHHCCCCEEEEEECCCCCC
RCAFEVAAFDQGAFVTYLGPSGSQIGHKESMKDTARVLGRMYDGIEYRGFGQEIVEELGQ
EEEEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
YAGVPVWNGLTDEFHPTQILADFMTMMEHLPGTPLNKIKFAYMGDARFNMGNSLMVGAAK
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHEEEEEECCCEECCCCCEEEEHHH
MGMEIHLVAPKAYWPDEKLVRECLDIAETTGAKIVLTENVETGVAGMDFIYTDVWVSMGE
CCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCC
AKEAWAERIRVMTPYQVNMDVIKQTGNPQVKFMHCLPAFHDEHTTMGKEIEQTYNMKGLE
HHHHHHHHHEECCCCCCCHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCE
VTDDVFESHHSIVFDEAENRMHTIKAVMVATLGA
ECHHHHHCCCCEEEECHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA