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The map label for this gene is rhtC [H]

Identifier: 167622505

GI number: 167622505

Start: 678248

End: 678907

Strand: Reverse

Name: rhtC [H]

Synonym: Shal_0565

Alternate gene names: 167622505

Gene position: 678907-678248 (Counterclockwise)

Preceding gene: 167622524

Following gene: 167622490

Centisome position: 12.99

GC content: 35.45

Gene sequence:

>660_bases
ATGGACATAAGCTTGATAGGGATTTTTGCTACTGTTGCCTTTGCTCATTTTTTAGCATTAATTAGCCCAGGCCCTGATTT
TGTTATCCTTGTAAAGAGTGCCGTTAAAAATGAAAGCAAAAAAGCCATAGGAGTCGCGCTGGGCATATCAATTGCAAATG
CATTATATATAGCATTGTGCTTAATTGGCGTGGGTTCATTATTAGCAAGTTCTGTATATATTATGATAGGGCTAAAAATT
GCAGGAGGGTTGTTTTTAATATATTTAGCAATTCAAGCCTTACGTGCAAAAAAAAGCGATTACGCTGGTTTGTCTTCTCA
AGTCAATCGTGGGGATCATAATGAGACCACTTTTTTCAAGGAGTTTATTGTTGGTTTTATGTCTGCAATTTTAAACCCAA
AAAACATTCTATTTTATTTAAGCTTATTTACGGTTGTGTTAACTAAAGATGTAAGCCTTACATTTAAAATCATGCTGGGA
ATTTGGATGACTTCCATCGTGTTTATATGGGATTCAGCAATTGTGATTTTTTTGTCTGGCGATAAAGTCAGGAGCAAGTT
TTCTAAGCTGGCTTATTATATTGATAAAGCAACTGGTGCTATTTTAGGCTTAGTCGGCTTTACAATCGTGAAGGCCGCGT
TTACTAAATCAAACGTATAA

Upstream 100 bases:

>100_bases
CGAGATACCGCTAATCCCCCGCAGACTATTATCGAAGTTAGCGCTAATACACTGTTATCTTTTATTGTAATTTTTGTGTT
TTTTTATGGAGTCACTTTAG

Downstream 100 bases:

>100_bases
TAAATGCTTAGTTGGAAAACCACCGTTGGCTATCGCTCCATGCTTTAGCCAACCAATAGTTTCCACTTTGCAAAAGGTTA
AGCCCCATCTCAGCCTAGAA

Product: lysine exporter protein LysE/YggA

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MDISLIGIFATVAFAHFLALISPGPDFVILVKSAVKNESKKAIGVALGISIANALYIALCLIGVGSLLASSVYIMIGLKI
AGGLFLIYLAIQALRAKKSDYAGLSSQVNRGDHNETTFFKEFIVGFMSAILNPKNILFYLSLFTVVLTKDVSLTFKIMLG
IWMTSIVFIWDSAIVIFLSGDKVRSKFSKLAYYIDKATGAILGLVGFTIVKAAFTKSNV

Sequences:

>Translated_219_residues
MDISLIGIFATVAFAHFLALISPGPDFVILVKSAVKNESKKAIGVALGISIANALYIALCLIGVGSLLASSVYIMIGLKI
AGGLFLIYLAIQALRAKKSDYAGLSSQVNRGDHNETTFFKEFIVGFMSAILNPKNILFYLSLFTVVLTKDVSLTFKIMLG
IWMTSIVFIWDSAIVIFLSGDKVRSKFSKLAYYIDKATGAILGLVGFTIVKAAFTKSNV
>Mature_219_residues
MDISLIGIFATVAFAHFLALISPGPDFVILVKSAVKNESKKAIGVALGISIANALYIALCLIGVGSLLASSVYIMIGLKI
AGGLFLIYLAIQALRAKKSDYAGLSSQVNRGDHNETTFFKEFIVGFMSAILNPKNILFYLSLFTVVLTKDVSLTFKIMLG
IWMTSIVFIWDSAIVIFLSGDKVRSKFSKLAYYIDKATGAILGLVGFTIVKAAFTKSNV

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=198, Percent_Identity=27.7777777777778, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786522, Length=197, Percent_Identity=22.8426395939086, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 23623; Mature: 23623

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDISLIGIFATVAFAHFLALISPGPDFVILVKSAVKNESKKAIGVALGISIANALYIALC
CCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHH
LIGVGSLLASSVYIMIGLKIAGGLFLIYLAIQALRAKKSDYAGLSSQVNRGDHNETTFFK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCHHHHHH
EFIVGFMSAILNPKNILFYLSLFTVVLTKDVSLTFKIMLGIWMTSIVFIWDSAIVIFLSG
HHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECC
DKVRSKFSKLAYYIDKATGAILGLVGFTIVKAAFTKSNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDISLIGIFATVAFAHFLALISPGPDFVILVKSAVKNESKKAIGVALGISIANALYIALC
CCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHH
LIGVGSLLASSVYIMIGLKIAGGLFLIYLAIQALRAKKSDYAGLSSQVNRGDHNETTFFK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCHHHHHH
EFIVGFMSAILNPKNILFYLSLFTVVLTKDVSLTFKIMLGIWMTSIVFIWDSAIVIFLSG
HHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECC
DKVRSKFSKLAYYIDKATGAILGLVGFTIVKAAFTKSNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]