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The map label for this gene is mtnN [H]

Identifier: 167622357

GI number: 167622357

Start: 489231

End: 490070

Strand: Reverse

Name: mtnN [H]

Synonym: Shal_0417

Alternate gene names: 167622357

Gene position: 490070-489231 (Counterclockwise)

Preceding gene: 167622358

Following gene: 167622356

Centisome position: 9.38

GC content: 46.19

Gene sequence:

>840_bases
ATGCCAACTTGCGAGCAGCTATTAACTGAAAAGTTAAACTCTGAACACTTAAACCCTGAACAGTTACACAATGAAAAGTT
ACCCTCAAAAATGCTAAATCCTATCTTAGTTCAAGGCGCGATGGACGTTGAAGTCGAGACTCTTGTTGCCGCCCTTAGCG
ATGTAAAACAAAAGACATTTGGTGCGTGGACTTTCTGGCAAGGTCTATTAGATGGCTACCCAGTTGTAGTGTCACGTACC
GAGATTGGTTTGGCTAACGCCGCCGCATCTACAACACTGGGCATTGCGCACTACCAGCCAAAAGTTATCATCAATCAGGG
CACCTCTGGTGGCCACGATCCAAAGCTATTTCGCTCTGACATCGTGATTGGTGCAACCAGCTTTAACATGGGCGCTTACA
AAATTGAGTTCGTAGAAAAAGGCCAAGGCATACACCCAACCACTTGGCAGAACTTCGATATGCCAATGTACCTACGTGAA
AACGGCGTTGTGGTTGAGCACAATCACTTTAAAGCCGACCCAGCGCTAGTTGAAATCGCCCTTTCGCAAGCAAGTAGCTA
CACCCACGGAAAAGTAGTAGTGGGTAGAATTGGTAGCTGTGACGAATGGAACCGTGAAGTTGACCGTATTAACTGGTTCC
ACGAGACCATGGGCACCTCAGTTGAAGAGATGGAAACCTCTGCGGCTGCGCAAGTTGCCGAAGCTTACAAACTCCCTTTT
GTGAGTATTCGCGTACTGTCTAATACCGACCAACATAAGCAAGACTTTGAGCCGCAAACGGCGATTGATTGTCAGGTTTA
TGTGCTTGATGTCATTAAGGCATTAATTAAGACCTTTTAA

Upstream 100 bases:

>100_bases
AGCCACCGAAACGGCAACAAGTATTTTACTTTTCATTTCGTTGTTTTGGCACATGCCGGATTGCTAATATCCGCGCACTT
TCCATTTGAAGTTATTTGTC

Downstream 100 bases:

>100_bases
AGCCAGTTTTAACTCTGGTTTTAGCTCTGGTTTTACTAGCCGTTTTACAAAGCACCTAAGCGACAGGATGAGTGACGGGA
ATAACAATCGTATTCCCGCC

Product: purine phosphorylase family 1

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase [H]

Number of amino acids: Translated: 279; Mature: 278

Protein sequence:

>279_residues
MPTCEQLLTEKLNSEHLNPEQLHNEKLPSKMLNPILVQGAMDVEVETLVAALSDVKQKTFGAWTFWQGLLDGYPVVVSRT
EIGLANAAASTTLGIAHYQPKVIINQGTSGGHDPKLFRSDIVIGATSFNMGAYKIEFVEKGQGIHPTTWQNFDMPMYLRE
NGVVVEHNHFKADPALVEIALSQASSYTHGKVVVGRIGSCDEWNREVDRINWFHETMGTSVEEMETSAAAQVAEAYKLPF
VSIRVLSNTDQHKQDFEPQTAIDCQVYVLDVIKALIKTF

Sequences:

>Translated_279_residues
MPTCEQLLTEKLNSEHLNPEQLHNEKLPSKMLNPILVQGAMDVEVETLVAALSDVKQKTFGAWTFWQGLLDGYPVVVSRT
EIGLANAAASTTLGIAHYQPKVIINQGTSGGHDPKLFRSDIVIGATSFNMGAYKIEFVEKGQGIHPTTWQNFDMPMYLRE
NGVVVEHNHFKADPALVEIALSQASSYTHGKVVVGRIGSCDEWNREVDRINWFHETMGTSVEEMETSAAAQVAEAYKLPF
VSIRVLSNTDQHKQDFEPQTAIDCQVYVLDVIKALIKTF
>Mature_278_residues
PTCEQLLTEKLNSEHLNPEQLHNEKLPSKMLNPILVQGAMDVEVETLVAALSDVKQKTFGAWTFWQGLLDGYPVVVSRTE
IGLANAAASTTLGIAHYQPKVIINQGTSGGHDPKLFRSDIVIGATSFNMGAYKIEFVEKGQGIHPTTWQNFDMPMYLREN
GVVVEHNHFKADPALVEIALSQASSYTHGKVVVGRIGSCDEWNREVDRINWFHETMGTSVEEMETSAAAQVAEAYKLPFV
SIRVLSNTDQHKQDFEPQTAIDCQVYVLDVIKALIKTF

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 31018; Mature: 30886

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTCEQLLTEKLNSEHLNPEQLHNEKLPSKMLNPILVQGAMDVEVETLVAALSDVKQKTF
CCCHHHHHHHHHCCCCCCHHHHHHHCCCHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHC
GAWTFWQGLLDGYPVVVSRTEIGLANAAASTTLGIAHYQPKVIINQGTSGGHDPKLFRSD
CHHHHHHHHHCCCCEEEEECCCCCHHHHHHHEEEEEECCCEEEEECCCCCCCCCHHHHCC
IVIGATSFNMGAYKIEFVEKGQGIHPTTWQNFDMPMYLRENGVVVEHNHFKADPALVEIA
EEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCEEEECCCEEEECCCCCCCHHHHHHH
LSQASSYTHGKVVVGRIGSCDEWNREVDRINWFHETMGTSVEEMETSAAAQVAEAYKLPF
HHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCE
VSIRVLSNTDQHKQDFEPQTAIDCQVYVLDVIKALIKTF
EEEEEECCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PTCEQLLTEKLNSEHLNPEQLHNEKLPSKMLNPILVQGAMDVEVETLVAALSDVKQKTF
CCHHHHHHHHHCCCCCCHHHHHHHCCCHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHC
GAWTFWQGLLDGYPVVVSRTEIGLANAAASTTLGIAHYQPKVIINQGTSGGHDPKLFRSD
CHHHHHHHHHCCCCEEEEECCCCCHHHHHHHEEEEEECCCEEEEECCCCCCCCCHHHHCC
IVIGATSFNMGAYKIEFVEKGQGIHPTTWQNFDMPMYLRENGVVVEHNHFKADPALVEIA
EEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCEEEECCCEEEECCCCCCCHHHHHHH
LSQASSYTHGKVVVGRIGSCDEWNREVDRINWFHETMGTSVEEMETSAAAQVAEAYKLPF
HHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCE
VSIRVLSNTDQHKQDFEPQTAIDCQVYVLDVIKALIKTF
EEEEEECCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA