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Identifier: 16752766

GI number: 16752766

Start: 536050

End: 536946

Strand: Direct

Name: Not Available

Synonym: CP0487

Alternate gene names: 16752766

Gene position: 536050-536946 (Clockwise)

Preceding gene: 16752765

Following gene: 16752768

Centisome position: 43.59

GC content: 38.91

Gene sequence:

>897_bases
ATGCACCTAGAAGAAGAGAATCAAGGCTGGGAAGCTTTACTTAGGAAAGTTTATCATCAGGAAGTGCCTCCAGCTATACT
GCTGCATGGATTTACCCTTCCTGTTTTACAGGATAAAGCAGAACAGTTAGCATCGGAGATTTTGCTATCGTCATCTCCAG
GTTCCGAACATAAAGTTTCTCAAAAGATTCATCCCGATATTTATCAATTCTTTCCAGAAGGAAAGGGAAGACTGCACTCT
ATAGATCTTCCTAGGGGAATTAAGAAGCAGATTTATATATCTCCTTTTGAAGCAAACTATAAGATCTACATTATTCACGA
AGCAGATCGAATGACTTTAGCTGCGATTTCCGCATTTTTAAAAGTCTTCGAAGAACCTCCGAAACATGCTGTTATCATAT
TGACAACAGCAAAAGTTCAGAGATTGCCAAAGACTATCATTTCTCGGAGTCTCTCTATTTTTATTGAGAGGGGAGAAAAA
ATCTTATGTTCCAAAGAGACGTTTTCTTATTTATTTCGCTATGCCCAATGTGAAATTCCCGTTACTGAAGTGTCTCAAAT
TATAAAAGAATCTTCAGAGACAGATAAACAGGTGTTAAGAGACAAGGTGCAACGATTCATGGAAGTGCTCCTAGAGCTAT
ATCGAGATCGTTATACTCTGAATTTAGGATTAAAGGCTTCAGCTTTAAACTATCCTGAGCATGTTAAGGAGATCCTACAA
TTGCCATTACTGCCTTTAGATAAGGTGCTTTTAATTGTGGAATCTGCCTGTCGGTCATTGAATAACTCCTCATCGGCAGC
ATCTGTTTTAGAATGGGTAGCTATTCAGTTGGTATCTCTCCAGTATAAAGAAAAGGAACTCGTTTCTGTCAGCCCCGGGC
AGGATCTATCCAATTAG

Upstream 100 bases:

>100_bases
CTCTTGCTAGTGCCGATCCTAGTCGTTACTTGGTTCTTGATGCTCGTGAATCACTAGCTAGTTTAATAGACAAAGTGATG
CTACATACGCAACTTGGGTT

Downstream 100 bases:

>100_bases
GAACTGTAACTTGCATTTTTTGGAATACTACAGAGGGAATTTCATGTCCTCCATGGAAAGAAACAAATTGCCCGTTCAAC
TTTGTTAATAGAAGATCATT

Product: DNA polymerase III subunit delta'

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MHLEEENQGWEALLRKVYHQEVPPAILLHGFTLPVLQDKAEQLASEILLSSSPGSEHKVSQKIHPDIYQFFPEGKGRLHS
IDLPRGIKKQIYISPFEANYKIYIIHEADRMTLAAISAFLKVFEEPPKHAVIILTTAKVQRLPKTIISRSLSIFIERGEK
ILCSKETFSYLFRYAQCEIPVTEVSQIIKESSETDKQVLRDKVQRFMEVLLELYRDRYTLNLGLKASALNYPEHVKEILQ
LPLLPLDKVLLIVESACRSLNNSSSAASVLEWVAIQLVSLQYKEKELVSVSPGQDLSN

Sequences:

>Translated_298_residues
MHLEEENQGWEALLRKVYHQEVPPAILLHGFTLPVLQDKAEQLASEILLSSSPGSEHKVSQKIHPDIYQFFPEGKGRLHS
IDLPRGIKKQIYISPFEANYKIYIIHEADRMTLAAISAFLKVFEEPPKHAVIILTTAKVQRLPKTIISRSLSIFIERGEK
ILCSKETFSYLFRYAQCEIPVTEVSQIIKESSETDKQVLRDKVQRFMEVLLELYRDRYTLNLGLKASALNYPEHVKEILQ
LPLLPLDKVLLIVESACRSLNNSSSAASVLEWVAIQLVSLQYKEKELVSVSPGQDLSN
>Mature_298_residues
MHLEEENQGWEALLRKVYHQEVPPAILLHGFTLPVLQDKAEQLASEILLSSSPGSEHKVSQKIHPDIYQFFPEGKGRLHS
IDLPRGIKKQIYISPFEANYKIYIIHEADRMTLAAISAFLKVFEEPPKHAVIILTTAKVQRLPKTIISRSLSIFIERGEK
ILCSKETFSYLFRYAQCEIPVTEVSQIIKESSETDKQVLRDKVQRFMEVLLELYRDRYTLNLGLKASALNYPEHVKEILQ
LPLLPLDKVLLIVESACRSLNNSSSAASVLEWVAIQLVSLQYKEKELVSVSPGQDLSN

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG0470

COG function: function code L; ATPase involved in DNA replication

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 33978; Mature: 33978

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLEEENQGWEALLRKVYHQEVPPAILLHGFTLPVLQDKAEQLASEILLSSSPGSEHKVS
CCCCCCCCCHHHHHHHHHHHCCCHHEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
QKIHPDIYQFFPEGKGRLHSIDLPRGIKKQIYISPFEANYKIYIIHEADRMTLAAISAFL
HHCCHHHHHHCCCCCCCEEEECCCCCCCCCEEEEEECCCEEEEEEECCCHHHHHHHHHHH
KVFEEPPKHAVIILTTAKVQRLPKTIISRSLSIFIERGEKILCSKETFSYLFRYAQCEIP
HHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHCCCC
VTEVSQIIKESSETDKQVLRDKVQRFMEVLLELYRDRYTLNLGLKASALNYPEHVKEILQ
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHCCCHHHHHHHHH
LPLLPLDKVLLIVESACRSLNNSSSAASVLEWVAIQLVSLQYKEKELVSVSPGQDLSN
CCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHEECCCCCCCCC
>Mature Secondary Structure
MHLEEENQGWEALLRKVYHQEVPPAILLHGFTLPVLQDKAEQLASEILLSSSPGSEHKVS
CCCCCCCCCHHHHHHHHHHHCCCHHEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
QKIHPDIYQFFPEGKGRLHSIDLPRGIKKQIYISPFEANYKIYIIHEADRMTLAAISAFL
HHCCHHHHHHCCCCCCCEEEECCCCCCCCCEEEEEECCCEEEEEEECCCHHHHHHHHHHH
KVFEEPPKHAVIILTTAKVQRLPKTIISRSLSIFIERGEKILCSKETFSYLFRYAQCEIP
HHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHCCCC
VTEVSQIIKESSETDKQVLRDKVQRFMEVLLELYRDRYTLNLGLKASALNYPEHVKEILQ
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHCCCHHHHHHHHH
LPLLPLDKVLLIVESACRSLNNSSSAASVLEWVAIQLVSLQYKEKELVSVSPGQDLSN
CCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]