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Identifier: 16752557

GI number: 16752557

Start: 273850

End: 275184

Strand: Direct

Name: Not Available

Synonym: CP0268

Alternate gene names: 16752557

Gene position: 273850-275184 (Clockwise)

Preceding gene: 16752556

Following gene: 16752561

Centisome position: 22.27

GC content: 45.24

Gene sequence:

>1335_bases
ATGAATTTTTCATTATTTTTATTTTTCCTGATAGCTATTCAGGGAATCTGCTTGTACGTGGGACGTCGTGGTAGCAAAAA
GGTAGAAGATCGCGAGAGCTATTTTCTTGCAGGAAGGAGTTTAAAAATCTTTCCTTTGATGATGACATTCATTGCCACCC
AAATCGGTGGCGGTGTACTTCTTGGGGCTGCTGAAGAGGCCTTCTGTTATGGTTATGGGGGGATTCTTTATCCTTTAGGA
GTCGCTTTAGGGTTGATTTTCTTAGGAATGGGGCCCGGGAAGCGGTTGGCAGAGGGATCGTTAACGACCGTAGTCTCTAT
CTTTGAAGTGTTTTATGGTTCTAAAAAGCTCCGTAAGATCGCATTTTTATTATCCGCAGGTTCCTTATTTTTCATCCTGG
TCGCTCAGGTGATTGCTTTAGATCGGTTGTTTAGCAGCTTCCCTTTTGGCAAGTACGTAACCGTAGCATTTTGGATTGTC
TTAGCATCCTATACCTCAACAGGAGGGTTTCGCGGGGTCGTACGTACTGATGTGATCCAAGCAGGATTTCTTCTTATTGC
GGTGCTCGTCTGTGGTGTTTCTGTATGGCTCTCTGTCCCTAAATCCTTGTCTGTGTTGGATCCTTTCCAATCACTTCCTT
GTGCGAAGCTTTCCAATTGGATATTCATGCCTATGCTCTTTATGCTTGTTGAGCAGGATATGGTGCAAAGGTGTGTGGCT
GCCTCCTCTCCAAAACGCTTGCAATGGGCGGCTGTAGGCGCAGGCCTTGTTCTTCTTCTTTTTAACTTTATCCCTTTATT
TTTAGGTTCTTTAGGAGCTAAAGCAGGCCTTAAAGCAGGATGCCCTCTGATTGATACCATTGCATATTTTTGCAATCCCT
CACTAGCAGCTGTGATGGCTGCTGCCATCGGCGTTGCGATTCTCTCTACCGCGGACTCTCTTATGAATGCTGTAAGCCAG
CTAATCGCTGAAGAATACCCTACGTTGAAAGCCCCTTATTATCGTTATTTAGTATTGGGTTTGGCGGTTGCAGCTCCTCT
TGTTGCTATTGGTTTTACAAACATCGTAGATGTCTTGATTTTAAGCTATAGCCTGTCAGTGTGTTGTCTTTCAGTCCCTG
TGGGTTTCTATCTTCTAGCTCCTAAAGGTCGCCGTGTGAGCGGAGCTGCTGCTTGGGCAGGAGTGCTCGTTGGTGCTCTG
GGCTATGGATGGGTTCAGATAGTCTCTTTGGGGATGTTTGGGGAGCTATTGGCTTGGGTAGGTTCTCTAGTCGCCTTTTC
CTTTGTAGGATTTATTGAGATCACTTGGAAAAACAAAGTCAAAACGCAAACTTAG

Upstream 100 bases:

>100_bases
TCACCACTCCTAATTTTCCTAGCATTTCTATCTTTAAGCTCAGCACCGTAGCTTGCTTAAAGGAAATATTTTTCATTTAG
GTTGTGGAGTTCTTTATTTT

Downstream 100 bases:

>100_bases
ATAACCACTGCATGAGAAGATATAACTAAAATAGATCCTGAGTTGTTTAGGTTTCTCTTAGATCTGATAGGTTGCGCTTA
GTAAGAGATCGTCAGTTTTT

Product: sodium:solute symporter family protein

Products: Na (I) [Cytoplasm]; pantothenate [Cytoplasm] [C]

Alternate protein names: Sodium Symporter; Sodium/Proline Sodium/Panthothenate Symporters; Proline Permease

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MNFSLFLFFLIAIQGICLYVGRRGSKKVEDRESYFLAGRSLKIFPLMMTFIATQIGGGVLLGAAEEAFCYGYGGILYPLG
VALGLIFLGMGPGKRLAEGSLTTVVSIFEVFYGSKKLRKIAFLLSAGSLFFILVAQVIALDRLFSSFPFGKYVTVAFWIV
LASYTSTGGFRGVVRTDVIQAGFLLIAVLVCGVSVWLSVPKSLSVLDPFQSLPCAKLSNWIFMPMLFMLVEQDMVQRCVA
ASSPKRLQWAAVGAGLVLLLFNFIPLFLGSLGAKAGLKAGCPLIDTIAYFCNPSLAAVMAAAIGVAILSTADSLMNAVSQ
LIAEEYPTLKAPYYRYLVLGLAVAAPLVAIGFTNIVDVLILSYSLSVCCLSVPVGFYLLAPKGRRVSGAAAWAGVLVGAL
GYGWVQIVSLGMFGELLAWVGSLVAFSFVGFIEITWKNKVKTQT

Sequences:

>Translated_444_residues
MNFSLFLFFLIAIQGICLYVGRRGSKKVEDRESYFLAGRSLKIFPLMMTFIATQIGGGVLLGAAEEAFCYGYGGILYPLG
VALGLIFLGMGPGKRLAEGSLTTVVSIFEVFYGSKKLRKIAFLLSAGSLFFILVAQVIALDRLFSSFPFGKYVTVAFWIV
LASYTSTGGFRGVVRTDVIQAGFLLIAVLVCGVSVWLSVPKSLSVLDPFQSLPCAKLSNWIFMPMLFMLVEQDMVQRCVA
ASSPKRLQWAAVGAGLVLLLFNFIPLFLGSLGAKAGLKAGCPLIDTIAYFCNPSLAAVMAAAIGVAILSTADSLMNAVSQ
LIAEEYPTLKAPYYRYLVLGLAVAAPLVAIGFTNIVDVLILSYSLSVCCLSVPVGFYLLAPKGRRVSGAAAWAGVLVGAL
GYGWVQIVSLGMFGELLAWVGSLVAFSFVGFIEITWKNKVKTQT
>Mature_444_residues
MNFSLFLFFLIAIQGICLYVGRRGSKKVEDRESYFLAGRSLKIFPLMMTFIATQIGGGVLLGAAEEAFCYGYGGILYPLG
VALGLIFLGMGPGKRLAEGSLTTVVSIFEVFYGSKKLRKIAFLLSAGSLFFILVAQVIALDRLFSSFPFGKYVTVAFWIV
LASYTSTGGFRGVVRTDVIQAGFLLIAVLVCGVSVWLSVPKSLSVLDPFQSLPCAKLSNWIFMPMLFMLVEQDMVQRCVA
ASSPKRLQWAAVGAGLVLLLFNFIPLFLGSLGAKAGLKAGCPLIDTIAYFCNPSLAAVMAAAIGVAILSTADSLMNAVSQ
LIAEEYPTLKAPYYRYLVLGLAVAAPLVAIGFTNIVDVLILSYSLSVCCLSVPVGFYLLAPKGRRVSGAAAWAGVLVGAL
GYGWVQIVSLGMFGELLAWVGSLVAFSFVGFIEITWKNKVKTQT

Specific function: Catalyzes The Sodium-Dependent Uptake Of Extracellular Pantothenate. [C]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 47581; Mature: 47581

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHEEEEECCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; pantothenate [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + pantothenate [Periplasm] = Na (I) [Cytoplasm] + pantothenate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA