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Identifier: 16752555

GI number: 16752555

Start: 271445

End: 271822

Strand: Direct

Name: Not Available

Synonym: CP0266

Alternate gene names: 16752555

Gene position: 271445-271822 (Clockwise)

Preceding gene: 16752554

Following gene: 16752556

Centisome position: 22.07

GC content: 40.48

Gene sequence:

>378_bases
TTGCCAACGTGCTTTGCGGTTAACGTTACAAGATCGAGGGATCATATGACAGTATTCAAACAAATTATCGATGGATTGAT
AGATTGTGAAAAGGTATTTGAAAACGAAAATTTCATAGCTATAAAAGATCGTTTTCCTCAAGCTCCTGTTCATCTTCTTA
TCATTCCTAAAAAACCTATACCACGATTTCAGGATATCCCAGGGGATGAGATGATTTTAATGGCAGAGGCTGGAAAGATC
GTGCAAGAGCTTGCTGCAGAATTTGGAATTGCCGATGGGTATCGTGTGGTTATCAACAACGGTGCTGAAGGAGGACAGGC
GGTATTTCACTTACATATTCATCTTTTAGGTGGGCGTCCTTTAGGTGCTATAGCCTAA

Upstream 100 bases:

>100_bases
CAGGTTTGTTAGGTAAAGAGTTGTCCAAAGTATCAGGGATTCCTGGGGCTGTGTTCTGCCATAAAGGTCTTTTCCTTTCT
GTATGGACAAATAGAGAAAG

Downstream 100 bases:

>100_bases
TTTTCTTTTGTTTCTGTGGATCCTTGTTCGGCTCGGAGTCCCTCCGTTATCAATTGTTGATCCAAGATTTTGCAAAAGTT
TCAGAAGAGGGCATAGGCCT

Product: HIT family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 125; Mature: 124

Protein sequence:

>125_residues
MPTCFAVNVTRSRDHMTVFKQIIDGLIDCEKVFENENFIAIKDRFPQAPVHLLIIPKKPIPRFQDIPGDEMILMAEAGKI
VQELAAEFGIADGYRVVINNGAEGGQAVFHLHIHLLGGRPLGAIA

Sequences:

>Translated_125_residues
MPTCFAVNVTRSRDHMTVFKQIIDGLIDCEKVFENENFIAIKDRFPQAPVHLLIIPKKPIPRFQDIPGDEMILMAEAGKI
VQELAAEFGIADGYRVVINNGAEGGQAVFHLHIHLLGGRPLGAIA
>Mature_124_residues
PTCFAVNVTRSRDHMTVFKQIIDGLIDCEKVFENENFIAIKDRFPQAPVHLLIIPKKPIPRFQDIPGDEMILMAEAGKIV
QELAAEFGIADGYRVVINNGAEGGQAVFHLHIHLLGGRPLGAIA

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI14211923, Length=105, Percent_Identity=42.8571428571429, Blast_Score=100, Evalue=5e-22,
Organism=Homo sapiens, GI4885413, Length=105, Percent_Identity=40, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1787346, Length=107, Percent_Identity=41.1214953271028, Blast_Score=76, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17506713, Length=105, Percent_Identity=41.9047619047619, Blast_Score=95, Evalue=9e-21,
Organism=Drosophila melanogaster, GI28574010, Length=105, Percent_Identity=42.8571428571429, Blast_Score=98, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24581222, Length=105, Percent_Identity=42.8571428571429, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: NA

Molecular weight: Translated: 13787; Mature: 13656

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00892 HIT_1 ; PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTCFAVNVTRSRDHMTVFKQIIDGLIDCEKVFENENFIAIKDRFPQAPVHLLIIPKKPI
CCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCCCC
PRFQDIPGDEMILMAEAGKIVQELAAEFGIADGYRVVINNGAEGGQAVFHLHIHLLGGRP
CCCCCCCCCCEEEEECHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEEEEEECCCC
LGAIA
CCCCC
>Mature Secondary Structure 
PTCFAVNVTRSRDHMTVFKQIIDGLIDCEKVFENENFIAIKDRFPQAPVHLLIIPKKPI
CCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCCCC
PRFQDIPGDEMILMAEAGKIVQELAAEFGIADGYRVVINNGAEGGQAVFHLHIHLLGGRP
CCCCCCCCCCEEEEECHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEEEEEECCCC
LGAIA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]