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Identifier: 16752347

GI number: 16752347

Start: 65328

End: 66347

Strand: Direct

Name: Not Available

Synonym: CP0053

Alternate gene names: NA

Gene position: 65328-66347 (Clockwise)

Preceding gene: 16752346

Following gene: 16752348

Centisome position: 5.31

GC content: 40.59

Gene sequence:

>1020_bases
ATGGAAGAAGCTGCGAAACACTTGGCAAAAGAATTTCTGTGTTCAGGAATTAACCTTTTTTTGAGCGGTGAATATGAGCA
AGCGGAAAAAAGACTGAAAGAAACCTTAGAATTAGACTCTACAGCAGCACTCGCTTATTGTTATTTAGGGATTATTGCTT
TAGAGACTGGAAGAGTCTCCGAGGCTTTGAACTGGTGTTCTAAAGGTTTAGCATCCGAGCCGGGAGACAGCTATCTCCGT
TATTGTTATGGTGTAGCGTTAGACCGGGGGAATCAATATGAAGCAGCTATCGAACAGTATAGTGCGTATGTTGCTTTGCA
TCCCGATGATGTTGAGTGCTGGTTTAGTCTTGGAAGTGTATATCATCGTTTGAAGAGACTTCAAGAGGCTTTAGATTGTT
TTGATAAGATCCTTGCACTTGATCCTTGGAATCCACAAAGTTTATATAATAAGGCAGTGATCCTTTCTGAAATGGACGAT
GAAGCGGAGTCCATTCGTTTGCTTGAAGTTGCTGTAGCGAAGAATCCCTTATATTGGAAAGCTTGGGTAAAGTTAGGTTT
TTTGCTTTCTCGAAGCAAACGATGGGACAAGGCTACTGAGGCTTATGAACGTGTTGTTCAGCTGCGACCTGATTTGTCTG
ATGGTCATTACAATTTAGGTTTATGTTATCTCACTTTAGATAAAACTCGATTAGCTTTGAAGGCTTTTCAAGAAGCGTTG
TTTCTCAATGCTGAAGATGCTGATGCACATTTTTATGTCGGACTTGCTCACTTGGATCTTAAGCAAATGCGGGAAGCGTA
TGAGGCTTTTAATAGCGCGTTGTCTATTAATTTAGAACATGAGCGCGCTCACTATCTTCTGGGCTATTTGCATCATATGC
AAGGAGAGACCGATAAGGCAACAAAAGAGCTTTTATTTTTGCAAAAAAAGGATTCTACGTTTGCTCCCTTATTGCAGAAG
ACTGTGGTGTCAGATCCCTCCTCAATGCAATTTGAAAGGCGTTTAGATACTATTTCTTAA

Upstream 100 bases:

>100_bases
CAACAAAGAGAATCTTTTTTAAGGGGATAGTTTTCTTTTGGCATGGTTTTCGCTCCTCATTTAGTTGAGATCAACGAATC
ATGTGCTGGGAGAAATATCC

Downstream 100 bases:

>100_bases
GGCATGTTAAGTAGAAAAAACGTCACAGCAATAAACTAGGGAAATAGTGTTTTCAATTGAAATTAGAAGACAAAAATTTT
TTATTTCCCTAGAATGGCTT

Product: type III secretion chaperone

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MEEAAKHLAKEFLCSGINLFLSGEYEQAEKRLKETLELDSTAALAYCYLGIIALETGRVSEALNWCSKGLASEPGDSYLR
YCYGVALDRGNQYEAAIEQYSAYVALHPDDVECWFSLGSVYHRLKRLQEALDCFDKILALDPWNPQSLYNKAVILSEMDD
EAESIRLLEVAVAKNPLYWKAWVKLGFLLSRSKRWDKATEAYERVVQLRPDLSDGHYNLGLCYLTLDKTRLALKAFQEAL
FLNAEDADAHFYVGLAHLDLKQMREAYEAFNSALSINLEHERAHYLLGYLHHMQGETDKATKELLFLQKKDSTFAPLLQK
TVVSDPSSMQFERRLDTIS

Sequences:

>Translated_339_residues
MEEAAKHLAKEFLCSGINLFLSGEYEQAEKRLKETLELDSTAALAYCYLGIIALETGRVSEALNWCSKGLASEPGDSYLR
YCYGVALDRGNQYEAAIEQYSAYVALHPDDVECWFSLGSVYHRLKRLQEALDCFDKILALDPWNPQSLYNKAVILSEMDD
EAESIRLLEVAVAKNPLYWKAWVKLGFLLSRSKRWDKATEAYERVVQLRPDLSDGHYNLGLCYLTLDKTRLALKAFQEAL
FLNAEDADAHFYVGLAHLDLKQMREAYEAFNSALSINLEHERAHYLLGYLHHMQGETDKATKELLFLQKKDSTFAPLLQK
TVVSDPSSMQFERRLDTIS
>Mature_339_residues
MEEAAKHLAKEFLCSGINLFLSGEYEQAEKRLKETLELDSTAALAYCYLGIIALETGRVSEALNWCSKGLASEPGDSYLR
YCYGVALDRGNQYEAAIEQYSAYVALHPDDVECWFSLGSVYHRLKRLQEALDCFDKILALDPWNPQSLYNKAVILSEMDD
EAESIRLLEVAVAKNPLYWKAWVKLGFLLSRSKRWDKATEAYERVVQLRPDLSDGHYNLGLCYLTLDKTRLALKAFQEAL
FLNAEDADAHFYVGLAHLDLKQMREAYEAFNSALSINLEHERAHYLLGYLHHMQGETDKATKELLFLQKKDSTFAPLLQK
TVVSDPSSMQFERRLDTIS

Specific function: Unknown

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 9 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307148, Length=297, Percent_Identity=25.5892255892256, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI32307150, Length=297, Percent_Identity=25.5892255892256, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI224809432, Length=226, Percent_Identity=24.7787610619469, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI83415184, Length=196, Percent_Identity=30.1020408163265, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI301336134, Length=196, Percent_Identity=30.1020408163265, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI115532690, Length=290, Percent_Identity=24.4827586206897, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI115532692, Length=269, Percent_Identity=24.5353159851301, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI17647755, Length=297, Percent_Identity=26.2626262626263, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24585827, Length=297, Percent_Identity=26.2626262626263, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24585829, Length=297, Percent_Identity=26.2626262626263, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24647123, Length=230, Percent_Identity=25.2173913043478, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24656717, Length=275, Percent_Identity=23.6363636363636, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI18110006, Length=275, Percent_Identity=23.6363636363636, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24652602, Length=305, Percent_Identity=21.9672131147541, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008940
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 38692; Mature: 38692

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEAAKHLAKEFLCSGINLFLSGEYEQAEKRLKETLELDSTAALAYCYLGIIALETGRVS
CCHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHH
EALNWCSKGLASEPGDSYLRYCYGVALDRGNQYEAAIEQYSAYVALHPDDVECWFSLGSV
HHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCEEEEECCCCHHHHHHHHHH
YHRLKRLQEALDCFDKILALDPWNPQSLYNKAVILSEMDDEAESIRLLEVAVAKNPLYWK
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEEECCCCHHHHHHHHHHHHHCCCCHHH
AWVKLGFLLSRSKRWDKATEAYERVVQLRPDLSDGHYNLGLCYLTLDKTRLALKAFQEAL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECHHHHHHHHHHHHH
FLNAEDADAHFYVGLAHLDLKQMREAYEAFNSALSINLEHERAHYLLGYLHHMQGETDKA
HCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHCCCCHHH
TKELLFLQKKDSTFAPLLQKTVVSDPSSMQFERRLDTIS
HHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCC
>Mature Secondary Structure
MEEAAKHLAKEFLCSGINLFLSGEYEQAEKRLKETLELDSTAALAYCYLGIIALETGRVS
CCHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHH
EALNWCSKGLASEPGDSYLRYCYGVALDRGNQYEAAIEQYSAYVALHPDDVECWFSLGSV
HHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCEEEEECCCCHHHHHHHHHH
YHRLKRLQEALDCFDKILALDPWNPQSLYNKAVILSEMDDEAESIRLLEVAVAKNPLYWK
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEEECCCCHHHHHHHHHHHHHCCCCHHH
AWVKLGFLLSRSKRWDKATEAYERVVQLRPDLSDGHYNLGLCYLTLDKTRLALKAFQEAL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECHHHHHHHHHHHHH
FLNAEDADAHFYVGLAHLDLKQMREAYEAFNSALSINLEHERAHYLLGYLHHMQGETDKA
HCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHCCCCHHH
TKELLFLQKKDSTFAPLLQKTVVSDPSSMQFERRLDTIS
HHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087; 9697413 [H]