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The map label for this gene is csd [H]

Identifier: 167041012

GI number: 167041012

Start: 2445781

End: 2446923

Strand: Reverse

Name: csd [H]

Synonym: Teth514_2402

Alternate gene names: 167041012

Gene position: 2446923-2445781 (Counterclockwise)

Preceding gene: 167041013

Following gene: 167041011

Centisome position: 99.58

GC content: 36.83

Gene sequence:

>1143_bases
ATGATTTATTTTGATAATGCTGCTACTTCTTGGCCTAAACCCGATGGAGTGTATAGGGAAGTAGAGAAAGTTTTAAGAAA
CTGCGGAAACCCTGGAAGAGGCGGACACAAAATGGCACTTGTATCAGGAAGGGTTATTTTTGAAGCCAGGCAAGAGATAT
GCAGCATTTTCAATATTAAAGACCCTATGAGAGTGGTATTTACATCTAATACAACAGAAGCTTTGAATATTGCGTTAAAA
GGCCTTTTGAAAGAAGGAGATCATGTAATAACTTCTAGTATGGAGCACAATTCTATGATAAGACCCCTTATGGCGTTGAA
AGAAAAGGGGATAGAAGTTACAATCGTGAAAGCAAATGAGGAAGGAAAGATTGACCCTGAGGATATAAGGAAAGCAATTA
CAACAAAAACAAAAATGATTGCCATAACCCATGCTTCCAATGTGACAGGTACAATAATGCCTATTGAGGAAATAGGAAAT
ATTGCCCGGGAAATGAATTTAATTTTCTTGGTGGATGCAGCCCAGACGGCTGGAATATTGCCTATAGATGTAGAAAAACA
AAACATCGACCTTTTAGCTTTTCCTGGCCACAAAGGATTGTACGGCCCTCAAGGTACAGGAGGATTATATGTAAGAGAAG
GTATAGATGTATTGCCTCTTGAAGAAGGGGGAACGGGAAGTAAGTCAGAATCAATGTATCAACCTGATTTGATGCCAGAC
AAGTTAGAAAGTGGTACTCCTAATACTCCAGGGATTGCAGGACTAAAGGAAGGAGTGAAATTTGTAAAAAACATAGGTGT
AAATGCTATATATCAACATGAAAGAAAGCTTACTAAAATGTTGATAGAAGGATTGGAGCAAATAAAAGAAGTTAAAATAT
ATGGTCCACACGAAATAGAAGAAAGAGTTGGAGTAGTTTCAATAACATTAAAAGATAGAGATGTAGGAGAAATAAGTTAT
ATTTTGGATAGAGACTTTGATATAGCCACTCGAGCGGGATTACACTGCGCTCCATTAGCCCATTCAACAATTGGCACATT
AAAGACTGGTACTTTAAGATTTGGAATTGGATATTTTAACACTGAAGAAGAAGTAGAAAAAGCTATAAAAGCTATTGAAA
TAATTTCGCAAAAAGCATTCTGA

Upstream 100 bases:

>100_bases
GCTAATGAGAAAAAATAAATATAAAATATAGTTAAGAACCCTAAAAGGAGGTTTGCATATATTATAATATCGGGAGATTT
AATTTAAAGGAGATAGGACT

Downstream 100 bases:

>100_bases
CGAATTGGAGGAGAAACTTATGCAAAATTTTTTAGATATTATTTCTCAAAATGCTACGCTGATTATTTTGTTTTTATCAG
TTTTATCAATTATAGAATTA

Product: cysteine desulfurase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MIYFDNAATSWPKPDGVYREVEKVLRNCGNPGRGGHKMALVSGRVIFEARQEICSIFNIKDPMRVVFTSNTTEALNIALK
GLLKEGDHVITSSMEHNSMIRPLMALKEKGIEVTIVKANEEGKIDPEDIRKAITTKTKMIAITHASNVTGTIMPIEEIGN
IAREMNLIFLVDAAQTAGILPIDVEKQNIDLLAFPGHKGLYGPQGTGGLYVREGIDVLPLEEGGTGSKSESMYQPDLMPD
KLESGTPNTPGIAGLKEGVKFVKNIGVNAIYQHERKLTKMLIEGLEQIKEVKIYGPHEIEERVGVVSITLKDRDVGEISY
ILDRDFDIATRAGLHCAPLAHSTIGTLKTGTLRFGIGYFNTEEEVEKAIKAIEIISQKAF

Sequences:

>Translated_380_residues
MIYFDNAATSWPKPDGVYREVEKVLRNCGNPGRGGHKMALVSGRVIFEARQEICSIFNIKDPMRVVFTSNTTEALNIALK
GLLKEGDHVITSSMEHNSMIRPLMALKEKGIEVTIVKANEEGKIDPEDIRKAITTKTKMIAITHASNVTGTIMPIEEIGN
IAREMNLIFLVDAAQTAGILPIDVEKQNIDLLAFPGHKGLYGPQGTGGLYVREGIDVLPLEEGGTGSKSESMYQPDLMPD
KLESGTPNTPGIAGLKEGVKFVKNIGVNAIYQHERKLTKMLIEGLEQIKEVKIYGPHEIEERVGVVSITLKDRDVGEISY
ILDRDFDIATRAGLHCAPLAHSTIGTLKTGTLRFGIGYFNTEEEVEKAIKAIEIISQKAF
>Mature_380_residues
MIYFDNAATSWPKPDGVYREVEKVLRNCGNPGRGGHKMALVSGRVIFEARQEICSIFNIKDPMRVVFTSNTTEALNIALK
GLLKEGDHVITSSMEHNSMIRPLMALKEKGIEVTIVKANEEGKIDPEDIRKAITTKTKMIAITHASNVTGTIMPIEEIGN
IAREMNLIFLVDAAQTAGILPIDVEKQNIDLLAFPGHKGLYGPQGTGGLYVREGIDVLPLEEGGTGSKSESMYQPDLMPD
KLESGTPNTPGIAGLKEGVKFVKNIGVNAIYQHERKLTKMLIEGLEQIKEVKIYGPHEIEERVGVVSITLKDRDVGEISY
ILDRDFDIATRAGLHCAPLAHSTIGTLKTGTLRFGIGYFNTEEEVEKAIKAIEIISQKAF

Specific function: Cysteine Desulfurases Mobilize The Sulfur From L- Cysteine To Yield L-Alanine, An Essential Step In Sulfur Metabolism For Biosynthesis Of A Variety Of Sulfur-Containing Biomolecules. Component Of The Suf Operon, Which Is Activated And Required Under Speci

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=385, Percent_Identity=29.3506493506493, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI156713448, Length=318, Percent_Identity=28.9308176100629, Blast_Score=102, Evalue=7e-22,
Organism=Escherichia coli, GI1787970, Length=389, Percent_Identity=30.5912596401028, Blast_Score=184, Evalue=6e-48,
Organism=Escherichia coli, GI48994898, Length=388, Percent_Identity=29.3814432989691, Blast_Score=151, Evalue=7e-38,
Organism=Escherichia coli, GI1789175, Length=391, Percent_Identity=28.1329923273657, Blast_Score=144, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI25143064, Length=381, Percent_Identity=29.6587926509186, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17533177, Length=334, Percent_Identity=27.8443113772455, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI193211090, Length=336, Percent_Identity=27.6785714285714, Blast_Score=86, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6319831, Length=388, Percent_Identity=30.9278350515464, Blast_Score=163, Evalue=4e-41,
Organism=Drosophila melanogaster, GI20129463, Length=397, Percent_Identity=29.7229219143577, Blast_Score=144, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 41713; Mature: 41713

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYFDNAATSWPKPDGVYREVEKVLRNCGNPGRGGHKMALVSGRVIFEARQEICSIFNIK
CEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECHHHHHHHHHHHHHHCCC
DPMRVVFTSNTTEALNIALKGLLKEGDHVITSSMEHNSMIRPLMALKEKGIEVTIVKANE
CCEEEEEECCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHCCCEEEEEEECC
EGKIDPEDIRKAITTKTKMIAITHASNVTGTIMPIEEIGNIAREMNLIFLVDAAQTAGIL
CCCCCHHHHHHHHHCCEEEEEEEECCCCCEEEEEHHHHHHHHHHCCEEEEEECCCCCCEE
PIDVEKQNIDLLAFPGHKGLYGPQGTGGLYVREGIDVLPLEEGGTGSKSESMYQPDLMPD
EEECCCCCCCEEEECCCCCCCCCCCCCCEEEECCCCEEEECCCCCCCCCCCCCCCCCCCH
KLESGTPNTPGIAGLKEGVKFVKNIGVNAIYQHERKLTKMLIEGLEQIKEVKIYGPHEIE
HHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHH
ERVGVVSITLKDRDVGEISYILDRDFDIATRAGLHCAPLAHSTIGTLKTGTLRFGIGYFN
HCCCEEEEEECCCCCCCEEEEECCCCCHHHHCCCEECCCCHHHHCCCCCCEEEEECCCCC
TEEEVEKAIKAIEIISQKAF
CHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIYFDNAATSWPKPDGVYREVEKVLRNCGNPGRGGHKMALVSGRVIFEARQEICSIFNIK
CEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECHHHHHHHHHHHHHHCCC
DPMRVVFTSNTTEALNIALKGLLKEGDHVITSSMEHNSMIRPLMALKEKGIEVTIVKANE
CCEEEEEECCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHCCCEEEEEEECC
EGKIDPEDIRKAITTKTKMIAITHASNVTGTIMPIEEIGNIAREMNLIFLVDAAQTAGIL
CCCCCHHHHHHHHHCCEEEEEEEECCCCCEEEEEHHHHHHHHHHCCEEEEEECCCCCCEE
PIDVEKQNIDLLAFPGHKGLYGPQGTGGLYVREGIDVLPLEEGGTGSKSESMYQPDLMPD
EEECCCCCCCEEEECCCCCCCCCCCCCCEEEECCCCEEEECCCCCCCCCCCCCCCCCCCH
KLESGTPNTPGIAGLKEGVKFVKNIGVNAIYQHERKLTKMLIEGLEQIKEVKIYGPHEIE
HHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHH
ERVGVVSITLKDRDVGEISYILDRDFDIATRAGLHCAPLAHSTIGTLKTGTLRFGIGYFN
HCCCEEEEEECCCCCCCEEEEECCCCCHHHHCCCEECCCCHHHHCCCCCCEEEEECCCCC
TEEEVEKAIKAIEIISQKAF
CHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]