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The map label for this gene is murA3 [H]

Identifier: 167040954

GI number: 167040954

Start: 2382224

End: 2383477

Strand: Reverse

Name: murA3 [H]

Synonym: Teth514_2343

Alternate gene names: 167040954

Gene position: 2383477-2382224 (Counterclockwise)

Preceding gene: 167040955

Following gene: 167040953

Centisome position: 97.0

GC content: 38.84

Gene sequence:

>1254_bases
ATGGAAAAGTTTGTAATCAAAGGAGGAAAGCCTCTTAGAGGAAGTGTACAGATAAGTGGTGCTAAAAATTCTGCTGTTGC
AATTCTTCCCGCAGCGTTATTGGCTGATACTCCGAGTGTGATAGATAATTTACCTGATATAAAAGATATAGAACTATTAG
CCCAGATGATACGCAATCTGGGAGGGAAAATAGAAAAGAAAAAACACGAAGTAGTAATTGACCCCATAGGCTTAAATTCC
TTTTACCCTCCTCGGGATTTGGCGAGCCAAATGAGGGCTTCTTATTATCTTATCGGAGCACTTTTAAGTAAGTTTAATGA
AGCAGTAATTGCGATGCCTGGGGGATGTAATATTGGCGTAAGACCTATTGACCAGCATATCAAGGGTTTTGAAGCTTTAG
GGGCAAAAACTACCATAGAGCATGGACTTATAAGGATTAAAGCTGATAAGTTGGTAGGGAATCATATATATTTTGATGTA
GTAAGCGTAGGTGCTACTATAAATTTGATGTTGGCATCGGTTAAAGCCGAAGGGGTAACAATATTAGAAAACTGTGCAAA
AGAGCCCCATGTAGTTGATGTAGCAAACTTTTTAAATGCCATGGGAGCGAATATTAAAGGTGCTGGTACAGATACTATAA
AGATAACAGGGGTAGACAAGCTTCACGGATGTCACTATACTATTATTCCTGACCAAATAGAAGCAGGAACTTACATGGTG
GCAGCTGCCGCAACAAAAGGTGATGTGTATATAAAAGGAATAATTCCAAATCACTTAGAAGCAATTATTGCAAAACTTGT
AGAAATGGGTGTCATTGTTGAGGAATACGATGATGTGATAAGAGTAAGAAGAGAAGGGCCTTTGAAACATGTTGATATAA
GGACTTTACCTTATCCTGGTTTTCCAACAGATATGCAACAGCCCTTTGCGGTGCTTTTGGCTTTGGCTGATGGCATAAGT
GTCATTACTGAAAATATCTATGAAAATAGATTTAAATATTTAAATGAGTTAGAGAAAATGGGAGCGAAAGTAAGAATAGA
AGGAAGAAATGCAATATTTGAAGGTGTAGAGAAGTTGACAGGTGCACCTCTTTACGCGACAGACTTAAGAGCAGGCGCAG
CGATGGTTATAGCAGGGCTTACTGCTGAGGGTACGACGGAGGTTATGGAGGTTTATCATATAGATAGGGGTTATGAAGCG
ATGGAAGTAAAGCTTCAACAATTAGGTGCTGATATAGTAAGGGTAAAAGAGTAA

Upstream 100 bases:

>100_bases
TTGCAAAATACTTGTAAAATATTTTAAATTGTATTAAAGTATATATTGTGATGATATTTGATTTATTTTAATTTAATTTG
ATTTGAAGGGAAGATTAAAA

Downstream 100 bases:

>100_bases
AAAGCTATAAAATTTTGCGTATAATGTGCTGCATAATATCTCATCCTATTTAGTGAGGTGATATTATGCAGCGTCAATTA
AAGAGTTTTTTTGCTGTTGC

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 3; UDP-N-acetylglucosamine enolpyruvyl transferase 3; EPT 3 [H]

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MEKFVIKGGKPLRGSVQISGAKNSAVAILPAALLADTPSVIDNLPDIKDIELLAQMIRNLGGKIEKKKHEVVIDPIGLNS
FYPPRDLASQMRASYYLIGALLSKFNEAVIAMPGGCNIGVRPIDQHIKGFEALGAKTTIEHGLIRIKADKLVGNHIYFDV
VSVGATINLMLASVKAEGVTILENCAKEPHVVDVANFLNAMGANIKGAGTDTIKITGVDKLHGCHYTIIPDQIEAGTYMV
AAAATKGDVYIKGIIPNHLEAIIAKLVEMGVIVEEYDDVIRVRREGPLKHVDIRTLPYPGFPTDMQQPFAVLLALADGIS
VITENIYENRFKYLNELEKMGAKVRIEGRNAIFEGVEKLTGAPLYATDLRAGAAMVIAGLTAEGTTEVMEVYHIDRGYEA
MEVKLQQLGADIVRVKE

Sequences:

>Translated_417_residues
MEKFVIKGGKPLRGSVQISGAKNSAVAILPAALLADTPSVIDNLPDIKDIELLAQMIRNLGGKIEKKKHEVVIDPIGLNS
FYPPRDLASQMRASYYLIGALLSKFNEAVIAMPGGCNIGVRPIDQHIKGFEALGAKTTIEHGLIRIKADKLVGNHIYFDV
VSVGATINLMLASVKAEGVTILENCAKEPHVVDVANFLNAMGANIKGAGTDTIKITGVDKLHGCHYTIIPDQIEAGTYMV
AAAATKGDVYIKGIIPNHLEAIIAKLVEMGVIVEEYDDVIRVRREGPLKHVDIRTLPYPGFPTDMQQPFAVLLALADGIS
VITENIYENRFKYLNELEKMGAKVRIEGRNAIFEGVEKLTGAPLYATDLRAGAAMVIAGLTAEGTTEVMEVYHIDRGYEA
MEVKLQQLGADIVRVKE
>Mature_417_residues
MEKFVIKGGKPLRGSVQISGAKNSAVAILPAALLADTPSVIDNLPDIKDIELLAQMIRNLGGKIEKKKHEVVIDPIGLNS
FYPPRDLASQMRASYYLIGALLSKFNEAVIAMPGGCNIGVRPIDQHIKGFEALGAKTTIEHGLIRIKADKLVGNHIYFDV
VSVGATINLMLASVKAEGVTILENCAKEPHVVDVANFLNAMGANIKGAGTDTIKITGVDKLHGCHYTIIPDQIEAGTYMV
AAAATKGDVYIKGIIPNHLEAIIAKLVEMGVIVEEYDDVIRVRREGPLKHVDIRTLPYPGFPTDMQQPFAVLLALADGIS
VITENIYENRFKYLNELEKMGAKVRIEGRNAIFEGVEKLTGAPLYATDLRAGAAMVIAGLTAEGTTEVMEVYHIDRGYEA
MEVKLQQLGADIVRVKE

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=418, Percent_Identity=48.3253588516746, Blast_Score=393, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 45177; Mature: 45177

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKFVIKGGKPLRGSVQISGAKNSAVAILPAALLADTPSVIDNLPDIKDIELLAQMIRNL
CCCEEECCCCCCCCEEEEECCCCCEEEEEHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHH
GGKIEKKKHEVVIDPIGLNSFYPPRDLASQMRASYYLIGALLSKFNEAVIAMPGGCNIGV
CCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCC
RPIDQHIKGFEALGAKTTIEHGLIRIKADKLVGNHIYFDVVSVGATINLMLASVKAEGVT
CCHHHHHHHHHHCCCCHHHCCCEEEEEECHHCCCEEEEEEHHHCCEEEEEEEECCCCCCH
ILENCAKEPHVVDVANFLNAMGANIKGAGTDTIKITGVDKLHGCHYTIIPDQIEAGTYMV
HHHHCCCCCCEEHHHHHHHHHCCCCCCCCCCEEEEECCHHHCCCEEEEECCCCCCCEEEE
AAAATKGDVYIKGIIPNHLEAIIAKLVEMGVIVEEYDDVIRVRREGPLKHVDIRTLPYPG
EEEECCCCEEEEECCCHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCEEEEEEECCCCC
FPTDMQQPFAVLLALADGISVITENIYENRFKYLNELEKMGAKVRIEGRNAIFEGVEKLT
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHC
GAPLYATDLRAGAAMVIAGLTAEGTTEVMEVYHIDRGYEAMEVKLQQLGADIVRVKE
CCCEEEHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEECC
>Mature Secondary Structure
MEKFVIKGGKPLRGSVQISGAKNSAVAILPAALLADTPSVIDNLPDIKDIELLAQMIRNL
CCCEEECCCCCCCCEEEEECCCCCEEEEEHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHH
GGKIEKKKHEVVIDPIGLNSFYPPRDLASQMRASYYLIGALLSKFNEAVIAMPGGCNIGV
CCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCC
RPIDQHIKGFEALGAKTTIEHGLIRIKADKLVGNHIYFDVVSVGATINLMLASVKAEGVT
CCHHHHHHHHHHCCCCHHHCCCEEEEEECHHCCCEEEEEEHHHCCEEEEEEEECCCCCCH
ILENCAKEPHVVDVANFLNAMGANIKGAGTDTIKITGVDKLHGCHYTIIPDQIEAGTYMV
HHHHCCCCCCEEHHHHHHHHHCCCCCCCCCCEEEEECCHHHCCCEEEEECCCCCCCEEEE
AAAATKGDVYIKGIIPNHLEAIIAKLVEMGVIVEEYDDVIRVRREGPLKHVDIRTLPYPG
EEEECCCCEEEEECCCHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCEEEEEEECCCCC
FPTDMQQPFAVLLALADGISVITENIYENRFKYLNELEKMGAKVRIEGRNAIFEGVEKLT
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHC
GAPLYATDLRAGAAMVIAGLTAEGTTEVMEVYHIDRGYEAMEVKLQQLGADIVRVKE
CCCEEEHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]