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The map label for this gene is wcaL [H]

Identifier: 167040899

GI number: 167040899

Start: 2293284

End: 2294405

Strand: Reverse

Name: wcaL [H]

Synonym: Teth514_2283

Alternate gene names: 167040899

Gene position: 2294405-2293284 (Counterclockwise)

Preceding gene: 167040900

Following gene: 167040898

Centisome position: 93.37

GC content: 32.8

Gene sequence:

>1122_bases
ATGAAGCATAATATACTCATATATCGACATCAATTATTTAAACCGTCGGAAGTTTTTATTTTGCAGCAAGCTGAGAGTTT
AAAAGAGTTTAATCCAATATATGTTGGGAGACAGGTTTTTGGGAATTATAAAGAAGGTACAAAAGTAGTAACACTTGAAG
ACGAAAATAAATTAGATGTGATGAAGAACATTTTGTTCCGAAATCCTATACCTTATGTAAAGAAGGTTAAAAGATTTAAT
CCTACTTTAATTCATGCTCACTTTGGTGTTGAAGGAGTTTATGCAATGGAACTGGCAAAAGCTTTAAAGATACCTTTAGT
AACAACTTTTCATGGGTTTGATGCAACAACAAGCACAAAGAATTTATTATTATCTAGAAAACCATCATGGATAAATTATG
CGTTATTTCGGAAGCAATTAGCCAAAAGAGGAGATATATTTATCTGTGTTTCTAATTACATTAGAGAGCGCGTTGTAAAA
ATGGGGTTTCCTGAAGATCGTACAATTACGCATTATATAGGTATTGATACAGATAAATTTAAACCAATCAAAGAAAATAC
AAAAGTACCATACATATTACATGTTGCCCGCTTAGTAGAAAATAAAGGTACTAAATATTTAATTGAAGCTTTTTCATATG
TTACAAAAAAAAATAAAGAGGTAGAATTGGTTATAATTGGAGATGGACCATTACGTACAGAATTAGAAGCTCTTTCTAAG
TCACTAAATATAGAAAATAAAGTACATTTTATGGGAGCCCAGCCTCACTCTGTAGTTATGGAATGGATGAAAAAAGCAAA
AATATTTTGTCTACCAAGTGTTACAGCACGTTCGGGAGCTACAGAAGGATTAGGGATGGTTTTTCTTGAAGCTGCAGCTT
TGGGAGTACCAAGTGTAGCGACTAATCTTGGAGGTATACCGGAAGCTGTAATTGATGGTGAAACAGGTTATTTGGTACCA
GAAAGGGCAGTTGATGAATTAGCTGAGCGATTAAATTATTTATTAGAAAATGAAACACTTCGTGATAAAATGGGTAAAGC
AGCACGAATAATGGTGGAAAGGAGATTCAATTTGCAATGTCAAACACAAAAACTGGAAGAGATTTACAAAAGTCTATTAT
AA

Upstream 100 bases:

>100_bases
TATGGAATAATTGGAGAAGAACATATGCAGCCTATATTGGCAGTAGCTTTGGGATTATTGTATACAAAAACACACTTTTA
TGAAAATGGGGGACGAAAGA

Downstream 100 bases:

>100_bases
AGAAACCACATATTGTTTTTTTGTCGAGGATATTACCTTTTCATAGTATAGGTGGTATGCAAGCTATTGCATGGGATCTT
GCACGTCAATTTGTTCGTGA

Product: group 1 glycosyl transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MKHNILIYRHQLFKPSEVFILQQAESLKEFNPIYVGRQVFGNYKEGTKVVTLEDENKLDVMKNILFRNPIPYVKKVKRFN
PTLIHAHFGVEGVYAMELAKALKIPLVTTFHGFDATTSTKNLLLSRKPSWINYALFRKQLAKRGDIFICVSNYIRERVVK
MGFPEDRTITHYIGIDTDKFKPIKENTKVPYILHVARLVENKGTKYLIEAFSYVTKKNKEVELVIIGDGPLRTELEALSK
SLNIENKVHFMGAQPHSVVMEWMKKAKIFCLPSVTARSGATEGLGMVFLEAAALGVPSVATNLGGIPEAVIDGETGYLVP
ERAVDELAERLNYLLENETLRDKMGKAARIMVERRFNLQCQTQKLEEIYKSLL

Sequences:

>Translated_373_residues
MKHNILIYRHQLFKPSEVFILQQAESLKEFNPIYVGRQVFGNYKEGTKVVTLEDENKLDVMKNILFRNPIPYVKKVKRFN
PTLIHAHFGVEGVYAMELAKALKIPLVTTFHGFDATTSTKNLLLSRKPSWINYALFRKQLAKRGDIFICVSNYIRERVVK
MGFPEDRTITHYIGIDTDKFKPIKENTKVPYILHVARLVENKGTKYLIEAFSYVTKKNKEVELVIIGDGPLRTELEALSK
SLNIENKVHFMGAQPHSVVMEWMKKAKIFCLPSVTARSGATEGLGMVFLEAAALGVPSVATNLGGIPEAVIDGETGYLVP
ERAVDELAERLNYLLENETLRDKMGKAARIMVERRFNLQCQTQKLEEIYKSLL
>Mature_373_residues
MKHNILIYRHQLFKPSEVFILQQAESLKEFNPIYVGRQVFGNYKEGTKVVTLEDENKLDVMKNILFRNPIPYVKKVKRFN
PTLIHAHFGVEGVYAMELAKALKIPLVTTFHGFDATTSTKNLLLSRKPSWINYALFRKQLAKRGDIFICVSNYIRERVVK
MGFPEDRTITHYIGIDTDKFKPIKENTKVPYILHVARLVENKGTKYLIEAFSYVTKKNKEVELVIIGDGPLRTELEALSK
SLNIENKVHFMGAQPHSVVMEWMKKAKIFCLPSVTARSGATEGLGMVFLEAAALGVPSVATNLGGIPEAVIDGETGYLVP
ERAVDELAERLNYLLENETLRDKMGKAARIMVERRFNLQCQTQKLEEIYKSLL

Specific function: Slime polysaccharide colanic acid biosynthesis. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Homo sapiens, GI11863130, Length=356, Percent_Identity=27.247191011236, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1788357, Length=301, Percent_Identity=32.5581395348837, Blast_Score=134, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI17532709, Length=276, Percent_Identity=29.7101449275362, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI9755344, Length=288, Percent_Identity=25.3472222222222, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24654571, Length=236, Percent_Identity=27.5423728813559, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: 2.-.-.- [C]

Molecular weight: Translated: 42509; Mature: 42509

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHNILIYRHQLFKPSEVFILQQAESLKEFNPIYVGRQVFGNYKEGTKVVTLEDENKLDV
CCCCEEEEEECCCCCCCEEEEHHHHHHHHCCCEEECHHHHCCCCCCCEEEEECCCCHHHH
MKNILFRNPIPYVKKVKRFNPTLIHAHFGVEGVYAMELAKALKIPLVTTFHGFDATTSTK
HHHHHHCCCCHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCCCCHH
NLLLSRKPSWINYALFRKQLAKRGDIFICVSNYIRERVVKMGFPEDRTITHYIGIDTDKF
HHHEECCCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCCCCCCCEEEEEECCCCCCC
KPIKENTKVPYILHVARLVENKGTKYLIEAFSYVTKKNKEVELVIIGDGPLRTELEALSK
CCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHH
SLNIENKVHFMGAQPHSVVMEWMKKAKIFCLPSVTARSGATEGLGMVFLEAAALGVPSVA
HCCCCCEEEEECCCHHHHHHHHHHCCEEEEECCCHHCCCCCCCHHHHHHHHHHCCCCHHH
TNLGGIPEAVIDGETGYLVPERAVDELAERLNYLLENETLRDKMGKAARIMVERRFNLQC
HHCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHCHHHHHHHHHHCCCEE
QTQKLEEIYKSLL
HHHHHHHHHHHHC
>Mature Secondary Structure
MKHNILIYRHQLFKPSEVFILQQAESLKEFNPIYVGRQVFGNYKEGTKVVTLEDENKLDV
CCCCEEEEEECCCCCCCEEEEHHHHHHHHCCCEEECHHHHCCCCCCCEEEEECCCCHHHH
MKNILFRNPIPYVKKVKRFNPTLIHAHFGVEGVYAMELAKALKIPLVTTFHGFDATTSTK
HHHHHHCCCCHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCCCCHH
NLLLSRKPSWINYALFRKQLAKRGDIFICVSNYIRERVVKMGFPEDRTITHYIGIDTDKF
HHHEECCCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCCCCCCCEEEEEECCCCCCC
KPIKENTKVPYILHVARLVENKGTKYLIEAFSYVTKKNKEVELVIIGDGPLRTELEALSK
CCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHH
SLNIENKVHFMGAQPHSVVMEWMKKAKIFCLPSVTARSGATEGLGMVFLEAAALGVPSVA
HCCCCCEEEEECCCHHHHHHHHHHCCEEEEECCCHHCCCCCCCHHHHHHHHHHCCCCHHH
TNLGGIPEAVIDGETGYLVPERAVDELAERLNYLLENETLRDKMGKAARIMVERRFNLQC
HHCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHCHHHHHHHHHHCCCEE
QTQKLEEIYKSLL
HHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1710759; 11677609 [H]