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The map label for this gene is ycsN [H]

Identifier: 167040874

GI number: 167040874

Start: 2260033

End: 2260950

Strand: Reverse

Name: ycsN [H]

Synonym: Teth514_2256

Alternate gene names: 167040874

Gene position: 2260950-2260033 (Counterclockwise)

Preceding gene: 167040875

Following gene: 167040873

Centisome position: 92.01

GC content: 34.2

Gene sequence:

>918_bases
ATGAAGTATATCAATATTGGTAATGGGGAGATAAAGGCATCGGCAATTGCATTGGGTTGTATGAGGATTGCTGATAAGTC
TGTAAAAGAAGTGGCGGAACTTATAAATACGGCTTTAGAAGAAGGTATAAATTTTTTTGACCATGCTGATATATATGGCG
GTGGCAAATCTGAAGAAGTTTTTGCTGAAGCTATAGATATGAAGCCTAGTATTAGAGAAAAAATCATTATTCAGACTAAG
TGTGGTATTAGAAAAGGGTATTATGACTTTTCAAAAGAACATATTTTAAAATCTGTCGATGGAAGCTTAAAAAGACTCAA
AACTGACTACATAGATGTTCTGTTATTACACCGTCCTGATACTTTGATGGAACCAGAAGAGGTTGCAGAGGCTTTTTCAA
TACTTCACAGCAGTGGCAAGGTTAGAAATTTCGGTGTAAGTAATTTTAATCCGATGCAGATAGAACTGCTTAGTAAGTAT
TTAAACCAAAAGCTTATCATAAACCAATTGCAGTTTAGTATTATGCATACAGGTATGATAGATTCTGGTTTTAATGTGAA
TATGAAAGTAGATCAGTCTATAGATAGAGATGGCAGTGTTTTGGAGTATTGCAGGTTAAAGAATATTACGATACAGGCAT
GGTCACCGTTCCAATATGGATTTTTTGAAGGCACTTTTTTAGGTAACGAAAAATTTAAAGAACTTAATGACAAAATTGAC
GAAATTGCTGCTAAAAAGGGTGTGCCAAATATTGCTATACCTATTGCATGGATTTTAAGACATCCAGCAAAGATACAACC
TATTGTTGGTACGACAAATCCTTCTCGATTGAAAGATATATGCAAAGCATCAGAGATTGAACTTACAAGAGAGGAATGGT
ATGAGTTATATAGAGCTGCAGGAAATAAATTACCATAA

Upstream 100 bases:

>100_bases
TTATATTGTAACCAGAGATAAGATAGGATTTAGTGAAAAACGGTTAGAAAAATTTTCGCTGTATGTTATAATAAAAACAA
AAAATTAAGAGGTGTTTTAA

Downstream 100 bases:

>100_bases
AGGCGAGTATTATTTTTTGCCGGATATTCACGAGGGGTTTGGGCTTACTATAGGAGGAGTTATGGCAATATGTGAGAATT
ATGCCAATTGTAAATTTAAT

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MKYINIGNGEIKASAIALGCMRIADKSVKEVAELINTALEEGINFFDHADIYGGGKSEEVFAEAIDMKPSIREKIIIQTK
CGIRKGYYDFSKEHILKSVDGSLKRLKTDYIDVLLLHRPDTLMEPEEVAEAFSILHSSGKVRNFGVSNFNPMQIELLSKY
LNQKLIINQLQFSIMHTGMIDSGFNVNMKVDQSIDRDGSVLEYCRLKNITIQAWSPFQYGFFEGTFLGNEKFKELNDKID
EIAAKKGVPNIAIPIAWILRHPAKIQPIVGTTNPSRLKDICKASEIELTREEWYELYRAAGNKLP

Sequences:

>Translated_305_residues
MKYINIGNGEIKASAIALGCMRIADKSVKEVAELINTALEEGINFFDHADIYGGGKSEEVFAEAIDMKPSIREKIIIQTK
CGIRKGYYDFSKEHILKSVDGSLKRLKTDYIDVLLLHRPDTLMEPEEVAEAFSILHSSGKVRNFGVSNFNPMQIELLSKY
LNQKLIINQLQFSIMHTGMIDSGFNVNMKVDQSIDRDGSVLEYCRLKNITIQAWSPFQYGFFEGTFLGNEKFKELNDKID
EIAAKKGVPNIAIPIAWILRHPAKIQPIVGTTNPSRLKDICKASEIELTREEWYELYRAAGNKLP
>Mature_305_residues
MKYINIGNGEIKASAIALGCMRIADKSVKEVAELINTALEEGINFFDHADIYGGGKSEEVFAEAIDMKPSIREKIIIQTK
CGIRKGYYDFSKEHILKSVDGSLKRLKTDYIDVLLLHRPDTLMEPEEVAEAFSILHSSGKVRNFGVSNFNPMQIELLSKY
LNQKLIINQLQFSIMHTGMIDSGFNVNMKVDQSIDRDGSVLEYCRLKNITIQAWSPFQYGFFEGTFLGNEKFKELNDKID
EIAAKKGVPNIAIPIAWILRHPAKIQPIVGTTNPSRLKDICKASEIELTREEWYELYRAAGNKLP

Specific function: Unknown

COG id: COG4989

COG function: function code R; Predicted oxidoreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=307, Percent_Identity=24.7557003257329, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI27436962, Length=307, Percent_Identity=24.4299674267101, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI27436966, Length=307, Percent_Identity=24.1042345276873, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI27436969, Length=312, Percent_Identity=24.0384615384615, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI4504825, Length=310, Percent_Identity=23.8709677419355, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI27436971, Length=162, Percent_Identity=29.0123456790123, Blast_Score=82, Evalue=6e-16,
Organism=Escherichia coli, GI48994888, Length=317, Percent_Identity=34.0694006309148, Blast_Score=184, Evalue=7e-48,
Organism=Escherichia coli, GI87081735, Length=329, Percent_Identity=26.7477203647416, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788070, Length=336, Percent_Identity=26.7857142857143, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788081, Length=291, Percent_Identity=24.7422680412371, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1789375, Length=319, Percent_Identity=23.8244514106583, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786400, Length=282, Percent_Identity=25.886524822695, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI212645785, Length=162, Percent_Identity=30.2469135802469, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17552492, Length=294, Percent_Identity=25.1700680272109, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6325169, Length=347, Percent_Identity=24.7838616714697, Blast_Score=93, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6323998, Length=321, Percent_Identity=25.8566978193146, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319958, Length=291, Percent_Identity=25.4295532646048, Blast_Score=69, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6319951, Length=288, Percent_Identity=26.3888888888889, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24644950, Length=322, Percent_Identity=26.3975155279503, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221378297, Length=342, Percent_Identity=24.8538011695906, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24640980, Length=352, Percent_Identity=23.0113636363636, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45549126, Length=352, Percent_Identity=23.0113636363636, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24646155, Length=174, Percent_Identity=30.4597701149425, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34483; Mature: 34483

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00136 SUBTILASE_ASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYINIGNGEIKASAIALGCMRIADKSVKEVAELINTALEEGINFFDHADIYGGGKSEEV
CCEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHH
FAEAIDMKPSIREKIIIQTKCGIRKGYYDFSKEHILKSVDGSLKRLKTDYIDVLLLHRPD
HHHHHCCCCCHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCC
TLMEPEEVAEAFSILHSSGKVRNFGVSNFNPMQIELLSKYLNQKLIINQLQFSIMHTGMI
CCCCHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DSGFNVNMKVDQSIDRDGSVLEYCRLKNITIQAWSPFQYGFFEGTFLGNEKFKELNDKID
CCCCEEEEEECCCCCCCCCHHHHHHHCCEEEEEECCCCCCCEEEEECCCHHHHHHHHHHH
EIAAKKGVPNIAIPIAWILRHPAKIQPIVGTTNPSRLKDICKASEIELTREEWYELYRAA
HHHHHCCCCCHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHC
GNKLP
CCCCC
>Mature Secondary Structure
MKYINIGNGEIKASAIALGCMRIADKSVKEVAELINTALEEGINFFDHADIYGGGKSEEV
CCEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHH
FAEAIDMKPSIREKIIIQTKCGIRKGYYDFSKEHILKSVDGSLKRLKTDYIDVLLLHRPD
HHHHHCCCCCHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCC
TLMEPEEVAEAFSILHSSGKVRNFGVSNFNPMQIELLSKYLNQKLIINQLQFSIMHTGMI
CCCCHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DSGFNVNMKVDQSIDRDGSVLEYCRLKNITIQAWSPFQYGFFEGTFLGNEKFKELNDKID
CCCCEEEEEECCCCCCCCCHHHHHHHCCEEEEEECCCCCCCEEEEECCCHHHHHHHHHHH
EIAAKKGVPNIAIPIAWILRHPAKIQPIVGTTNPSRLKDICKASEIELTREEWYELYRAA
HHHHHCCCCCHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHC
GNKLP
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]