Click here to switch to the map view.

The map label for this gene is pdxT

Identifier: 167040860

GI number: 167040860

Start: 2242472

End: 2243041

Strand: Reverse

Name: pdxT

Synonym: Teth514_2240

Alternate gene names: 167040860

Gene position: 2243041-2242472 (Counterclockwise)

Preceding gene: 167040861

Following gene: 167040859

Centisome position: 91.28

GC content: 36.84

Gene sequence:

>570_bases
TTGCGCGTTGGAGTATTGGCAATTCAGGGCTCTGTTAGAGAACATATTGAAAAATTAAAGCTTATAGATGGTGTAGAAGC
TGTTTTGGCAAAAGACAAAAATACTCTGCTAAGCTTAGATGCATTGATTATACCGGGTGGCGAAAGCACTGCAATAGGGA
AAATGATTGTAGATTTTGGACTCAAAGATGCTATTTTAAAGCTGAATGAGAGGAAAATTCCCATATGGGGCACTTGTGCT
GGCATGATACTTATGGCAAAATATATAGTTAATGATGACAAAGTGCACCTTGGAATAATGGATATTTCAGTTAAAAGAAA
TGCATATGGCAGTCAACTTGACAGCTTTAAAACAAAGCTTATAATACCAGCAGTTTCCAATAATGAGATAGAGGCGGTTT
TTATAAGGGCTCCGTATATAGAAAATGTAGGGAATGGTGTCAGGATACTTGCGAAGCACCAAGGTAAAATTGTGGCAGCA
CAGCAAGATAATTTGCTTGCTACCTCTTTTCATCCCGAACTTACTGATGATTTGAGTTTTTATAAATATTTCTTGAGGCT
TAACTCTTAA

Upstream 100 bases:

>100_bases
ATATTGGCAGAAGTTTCAGAAGGATTGGGAGAAGCCATGCAGAGTATTGATATAAGAAAACTTGATGAAAAAGATCTATA
TGCTTCAAGGGGATGGTAGT

Downstream 100 bases:

>100_bases
GCCTTTTTATTTTATAAAAAATTTTTTAAAGGCTCTTTGTCAAGAGTTGGGGTGGGTATTTTTCTGAATGCCCGCCCTTT
AGTTTTATGTCTTTTATCTT

Product: SNO glutamine amidotransferase

Products: NA

Alternate protein names: Glutamine amidotransferase glutaminase subunit pdxT

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MRVGVLAIQGSVREHIEKLKLIDGVEAVLAKDKNTLLSLDALIIPGGESTAIGKMIVDFGLKDAILKLNERKIPIWGTCA
GMILMAKYIVNDDKVHLGIMDISVKRNAYGSQLDSFKTKLIIPAVSNNEIEAVFIRAPYIENVGNGVRILAKHQGKIVAA
QQDNLLATSFHPELTDDLSFYKYFLRLNS

Sequences:

>Translated_189_residues
MRVGVLAIQGSVREHIEKLKLIDGVEAVLAKDKNTLLSLDALIIPGGESTAIGKMIVDFGLKDAILKLNERKIPIWGTCA
GMILMAKYIVNDDKVHLGIMDISVKRNAYGSQLDSFKTKLIIPAVSNNEIEAVFIRAPYIENVGNGVRILAKHQGKIVAA
QQDNLLATSFHPELTDDLSFYKYFLRLNS
>Mature_189_residues
MRVGVLAIQGSVREHIEKLKLIDGVEAVLAKDKNTLLSLDALIIPGGESTAIGKMIVDFGLKDAILKLNERKIPIWGTCA
GMILMAKYIVNDDKVHLGIMDISVKRNAYGSQLDSFKTKLIIPAVSNNEIEAVFIRAPYIENVGNGVRILAKHQGKIVAA
QQDNLLATSFHPELTDDLSFYKYFLRLNS

Specific function: Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to pdxS

COG id: COG0311

COG function: function code H; Predicted glutamine amidotransferase involved in pyridoxine biosynthesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine amidotransferase pdxT/SNO family

Homologues:

Organism=Saccharomyces cerevisiae, GI6323995, Length=213, Percent_Identity=39.906103286385, Blast_Score=125, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6321048, Length=213, Percent_Identity=39.4366197183099, Blast_Score=122, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6323742, Length=207, Percent_Identity=36.7149758454106, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXT_THEP3 (B0KAS0)

Other databases:

- EMBL:   CP000924
- RefSeq:   YP_001665540.1
- ProteinModelPortal:   B0KAS0
- SMR:   B0KAS0
- GeneID:   5874795
- GenomeReviews:   CP000924_GR
- KEGG:   tpd:Teth39_1559
- HOGENOM:   HBG292341
- OMA:   QGDVREH
- ProtClustDB:   CLSK900948
- BioCyc:   TPSE340099:TETH39_1559-MONOMER
- HAMAP:   MF_01615
- InterPro:   IPR002161
- InterPro:   IPR021196
- PIRSF:   PIRSF005639
- TIGRFAMs:   TIGR03800

Pfam domain/function: PF01174 SNO

EC number: NA

Molecular weight: Translated: 20833; Mature: 20833

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS01236 PDXT_SNO_1; PS51130 PDXT_SNO_2

Important sites: ACT_SITE 79-79 ACT_SITE 171-171 ACT_SITE 173-173 BINDING 106-106

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVGVLAIQGSVREHIEKLKLIDGVEAVLAKDKNTLLSLDALIIPGGESTAIGKMIVDFG
CCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHHHHCC
LKDAILKLNERKIPIWGTCAGMILMAKYIVNDDKVHLGIMDISVKRNAYGSQLDSFKTKL
CHHHHHEECCCCCCEEHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCCHHHCCCEEE
IIPAVSNNEIEAVFIRAPYIENVGNGVRILAKHQGKIVAAQQDNLLATSFHPELTDDLSF
EEEECCCCCEEEEEEECCCHHCCCCCEEEEEECCCEEEEEECCCEEEEECCCCCCHHHHH
YKYFLRLNS
HHHEEEECC
>Mature Secondary Structure
MRVGVLAIQGSVREHIEKLKLIDGVEAVLAKDKNTLLSLDALIIPGGESTAIGKMIVDFG
CCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHHHHCC
LKDAILKLNERKIPIWGTCAGMILMAKYIVNDDKVHLGIMDISVKRNAYGSQLDSFKTKL
CHHHHHEECCCCCCEEHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCCHHHCCCEEE
IIPAVSNNEIEAVFIRAPYIENVGNGVRILAKHQGKIVAAQQDNLLATSFHPELTDDLSF
EEEECCCCCEEEEEEECCCHHCCCCCEEEEEECCCEEEEEECCCEEEEECCCCCCHHHHH
YKYFLRLNS
HHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA