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The map label for this gene is pgsA1 [H]

Identifier: 167040843

GI number: 167040843

Start: 2223434

End: 2223949

Strand: Reverse

Name: pgsA1 [H]

Synonym: Teth514_2221

Alternate gene names: 167040843

Gene position: 2223949-2223434 (Counterclockwise)

Preceding gene: 167040844

Following gene: 167040842

Centisome position: 90.51

GC content: 30.43

Gene sequence:

>516_bases
ATGAATATACCAAATTTTCTTACACTTGTTAGATTTTTACTTATACCTCTTTTTGTATACACTTTTTTTTATGTTCCCGA
GGGAAATACTTATGCTGCAGTGATTTTTATATTATCAGGTATTACGGATATTTTGGATGGTTATATAGCGAGGCACTATA
ACCAAGTGACAAAAATAGGTACTTTGCTTGACCCTCTTGCGGACAAGTTGATGATACTTACTGTTTTGACCAGTTTATGG
ATAAAAGATTTAATTCCTTTTTTTGTTATTGCTATTTTAATGGTAAAAGAACTATCAATGATAATAGGTGCTGCGATACT
TTATAAAAAGCAAGAAATTGCTATACCTGCTAATAACTATGGCAAAGCTGCGACACTTTTCTTTTATATTGCGATAATTT
TTTCAATTTTTAAGTGGCCTTATGGATTTACTTTGATGATTATAGCACTGTTATTGGCTATTTTAGCCTTTGTTATCTAT
ACGTTGGAGTTTTATAAAAGGAGCACAGATAATTAA

Upstream 100 bases:

>100_bases
ATGAGATAGAAGTTCCTGTAAATGTGGCCCGATAAGGGCCTTTTACTTTTGATTTTTTTGTATTATAATTTTATCAAACT
TGACAAGTAGAGGTGTTTAG

Downstream 100 bases:

>100_bases
GAGGAAGTAAGTGCTTCTACAGAAGAGCAGCTTTCAGATGTGGGAAAACCCAAACATTTTGTTTATTTTACTATCTGTGA
TAAAATAGTTATACGTAAAA

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MNIPNFLTLVRFLLIPLFVYTFFYVPEGNTYAAVIFILSGITDILDGYIARHYNQVTKIGTLLDPLADKLMILTVLTSLW
IKDLIPFFVIAILMVKELSMIIGAAILYKKQEIAIPANNYGKAATLFFYIAIIFSIFKWPYGFTLMIIALLLAILAFVIY
TLEFYKRSTDN

Sequences:

>Translated_171_residues
MNIPNFLTLVRFLLIPLFVYTFFYVPEGNTYAAVIFILSGITDILDGYIARHYNQVTKIGTLLDPLADKLMILTVLTSLW
IKDLIPFFVIAILMVKELSMIIGAAILYKKQEIAIPANNYGKAATLFFYIAIIFSIFKWPYGFTLMIIALLLAILAFVIY
TLEFYKRSTDN
>Mature_171_residues
MNIPNFLTLVRFLLIPLFVYTFFYVPEGNTYAAVIFILSGITDILDGYIARHYNQVTKIGTLLDPLADKLMILTVLTSLW
IKDLIPFFVIAILMVKELSMIIGAAILYKKQEIAIPANNYGKAATLFFYIAIIFSIFKWPYGFTLMIIALLLAILAFVIY
TLEFYKRSTDN

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Homo sapiens, GI10092647, Length=109, Percent_Identity=38.5321100917431, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI188536108, Length=109, Percent_Identity=38.5321100917431, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1788220, Length=73, Percent_Identity=47.945205479452, Blast_Score=73, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71984834, Length=115, Percent_Identity=34.7826086956522, Blast_Score=68, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71984838, Length=115, Percent_Identity=34.7826086956522, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6320059, Length=110, Percent_Identity=40.9090909090909, Blast_Score=69, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24650130, Length=107, Percent_Identity=37.3831775700935, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24650126, Length=107, Percent_Identity=37.3831775700935, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24650128, Length=107, Percent_Identity=37.3831775700935, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 19528; Mature: 19528

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIPNFLTLVRFLLIPLFVYTFFYVPEGNTYAAVIFILSGITDILDGYIARHYNQVTKIG
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLLDPLADKLMILTVLTSLWIKDLIPFFVIAILMVKELSMIIGAAILYKKQEIAIPANNY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GKAATLFFYIAIIFSIFKWPYGFTLMIIALLLAILAFVIYTLEFYKRSTDN
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNIPNFLTLVRFLLIPLFVYTFFYVPEGNTYAAVIFILSGITDILDGYIARHYNQVTKIG
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLLDPLADKLMILTVLTSLWIKDLIPFFVIAILMVKELSMIIGAAILYKKQEIAIPANNY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GKAATLFFYIAIIFSIFKWPYGFTLMIIALLLAILAFVIYTLEFYKRSTDN
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]