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The map label for this gene is nuoG [C]

Identifier: 167040761

GI number: 167040761

Start: 2141808

End: 2143553

Strand: Reverse

Name: nuoG [C]

Synonym: Teth514_2138

Alternate gene names: 167040761

Gene position: 2143553-2141808 (Counterclockwise)

Preceding gene: 167040762

Following gene: 167040760

Centisome position: 87.23

GC content: 37.17

Gene sequence:

>1746_bases
ATGGACAAAGTTCGTGTTATGATAGACAGCATCACTGTAGAAGTTCCCTCCCATTACACGGTATTGGAAGCAGCAAAAGA
AGCAGGCATAGATATTCCTACACTGTGTTACCTCAAGGAAATTAATCAAATTGGCGCTTGTCGTATATGTGTAGTTGAAA
TAGAAGGAGTTAGAAATTTACAAACCTCCTGCACTTATCCGGTATTTGATGGTATGAAAGTGTATACAAATACACCTAAA
GTTAGAGAAGCGCGGAAATTAAATCTTGAGCTTATACTTTCAAATCATGATAGAAGCTGTTTGACTTGTATTAGAAATAC
TAACTGTGAGCTTCAATCATTGTCTAAAAAATTAGGAGTAGATGAAATAAGGTTTGAAGGTGAAAATATAAAGTATTCTA
TAGATAATGCTTCTCCTTCTATTGTAAGGGACCCAAATAAGTGTGTGCTTTGTAGAAGATGTGTATCAGTATGTTCAGAA
GTGCAAAACGTATTTGCTATTGGAATGGTAAATAGAGGATTTAATACAATGGTAGCACCTTCTTTTGGCAGAAGTTTAAA
AGATTCTCCTTGTATAAGCTGTGGACAGTGTATTGAGGTATGTCCTGTTGGAGCTATATATGAAAAAGACCACACAAAGA
GAGTTTATGAGGCTTTAGCTGATGAGAAAAAATATGTAGTAGCTCAAACAGCTCCAGCTGTAAGAGTAGCATTAGGTGAA
GAGTTTGGCATGCCAATAGGAAGTATTGTTACAGGAAAAATGGTAGCAGCTTTGAGAAGAATGGGTTTTGATGCGATATT
TGATACGAATTTTGCAGCAGACTTGACTATAATGGAGGAAGGTTCGGAACTTCTTGAAAGGCTTAAAAATGGCGGAAAAC
TTCCTATGATAACTTCCTGTAGCCCTGGTTGGATAGCTTTCTGTGAAAAATATTATCCAGAATTTATAGATAATCTTTCA
ACTTGTAAGTCTCCTCACATGATGATGGGGGCATTAGTAAAGAGTTATTATGCAGAAAAGAAAGGGCTTAATCCTGAGGA
TATATATATAGTATCTATTATGCCATGTACTGCTAAAAAACTAGAGATTGAAAGGCCAGAAATGCAGCATAATGGAATAA
AAGATGTAGATGCTGTCCTTACCACAAGAGAATTGGCGAGAATGATAAAAGAAATGGGCATTGACTTTGTAAATCTTCCT
GATGAAGAATATGACGAACCTCTTGGAATGTCCACGGGTGCGGCAGTAATATTTGGAGCTACAGGTGGAGTTATGGAGGC
AGCTTTAAGGACAGTTGCGGATATTGTAGAAGGGAAAGATTTAGACAAATTTGATTATGAAGAAGTGAGAGGGTTAGAAG
GTGTTAGAGAGGCTACTATAAGAATAGATGGTAAGGACATAAAAGTTGCCATAGCAAATGGAACAGGAAATGCGAAGAAA
CTTCTTGACAAAGTAAAAGCTGGCGAGGTAGAGTATCACTTCATAGAGGTAATGGGCTGCCCAGGAGGATGTATAATGGG
AGGCGGTCAGCCGATTCACAATCCAAATGAAATGGAAAAAGTAAAAGAATTAAGAGCGAAGGCTATTTACGAAGCAGATA
AAAATTTGCCTATCAGAAAATCTCACAAAAATCCTGCAATACAAAAACTCTATGAAGAATTTTTGGGCAGTCCTTTAAGC
GAAAAGTCTCATCACTTGCTCCACACTCATTATTCCAAGAAGGAGTTGTATCCTCTGGTAAAATAA

Upstream 100 bases:

>100_bases
ATGTAATTGACCAAGACAAATGTATCAAGTGCGGCACATGTATTGAAAAATGTCCATTTGGCGCAATATACAAAAAATAA
TTGAGGAAGGAGTGTAAAAG

Downstream 100 bases:

>100_bases
ATTTAATTAATAGTAAAGCTTCCAATACCTTATTGGGAGCTTTACCATTTTTTTATTTTAAAGTTAGTTATAGAAATGTA
TATAATTTGTGATATAATAA

Product: hydrogenase, Fe-only

Products: NA

Alternate protein names: CpI; Fe-only hydrogenase; [Fe] hydrogenase [H]

Number of amino acids: Translated: 581; Mature: 581

Protein sequence:

>581_residues
MDKVRVMIDSITVEVPSHYTVLEAAKEAGIDIPTLCYLKEINQIGACRICVVEIEGVRNLQTSCTYPVFDGMKVYTNTPK
VREARKLNLELILSNHDRSCLTCIRNTNCELQSLSKKLGVDEIRFEGENIKYSIDNASPSIVRDPNKCVLCRRCVSVCSE
VQNVFAIGMVNRGFNTMVAPSFGRSLKDSPCISCGQCIEVCPVGAIYEKDHTKRVYEALADEKKYVVAQTAPAVRVALGE
EFGMPIGSIVTGKMVAALRRMGFDAIFDTNFAADLTIMEEGSELLERLKNGGKLPMITSCSPGWIAFCEKYYPEFIDNLS
TCKSPHMMMGALVKSYYAEKKGLNPEDIYIVSIMPCTAKKLEIERPEMQHNGIKDVDAVLTTRELARMIKEMGIDFVNLP
DEEYDEPLGMSTGAAVIFGATGGVMEAALRTVADIVEGKDLDKFDYEEVRGLEGVREATIRIDGKDIKVAIANGTGNAKK
LLDKVKAGEVEYHFIEVMGCPGGCIMGGGQPIHNPNEMEKVKELRAKAIYEADKNLPIRKSHKNPAIQKLYEEFLGSPLS
EKSHHLLHTHYSKKELYPLVK

Sequences:

>Translated_581_residues
MDKVRVMIDSITVEVPSHYTVLEAAKEAGIDIPTLCYLKEINQIGACRICVVEIEGVRNLQTSCTYPVFDGMKVYTNTPK
VREARKLNLELILSNHDRSCLTCIRNTNCELQSLSKKLGVDEIRFEGENIKYSIDNASPSIVRDPNKCVLCRRCVSVCSE
VQNVFAIGMVNRGFNTMVAPSFGRSLKDSPCISCGQCIEVCPVGAIYEKDHTKRVYEALADEKKYVVAQTAPAVRVALGE
EFGMPIGSIVTGKMVAALRRMGFDAIFDTNFAADLTIMEEGSELLERLKNGGKLPMITSCSPGWIAFCEKYYPEFIDNLS
TCKSPHMMMGALVKSYYAEKKGLNPEDIYIVSIMPCTAKKLEIERPEMQHNGIKDVDAVLTTRELARMIKEMGIDFVNLP
DEEYDEPLGMSTGAAVIFGATGGVMEAALRTVADIVEGKDLDKFDYEEVRGLEGVREATIRIDGKDIKVAIANGTGNAKK
LLDKVKAGEVEYHFIEVMGCPGGCIMGGGQPIHNPNEMEKVKELRAKAIYEADKNLPIRKSHKNPAIQKLYEEFLGSPLS
EKSHHLLHTHYSKKELYPLVK
>Mature_581_residues
MDKVRVMIDSITVEVPSHYTVLEAAKEAGIDIPTLCYLKEINQIGACRICVVEIEGVRNLQTSCTYPVFDGMKVYTNTPK
VREARKLNLELILSNHDRSCLTCIRNTNCELQSLSKKLGVDEIRFEGENIKYSIDNASPSIVRDPNKCVLCRRCVSVCSE
VQNVFAIGMVNRGFNTMVAPSFGRSLKDSPCISCGQCIEVCPVGAIYEKDHTKRVYEALADEKKYVVAQTAPAVRVALGE
EFGMPIGSIVTGKMVAALRRMGFDAIFDTNFAADLTIMEEGSELLERLKNGGKLPMITSCSPGWIAFCEKYYPEFIDNLS
TCKSPHMMMGALVKSYYAEKKGLNPEDIYIVSIMPCTAKKLEIERPEMQHNGIKDVDAVLTTRELARMIKEMGIDFVNLP
DEEYDEPLGMSTGAAVIFGATGGVMEAALRTVADIVEGKDLDKFDYEEVRGLEGVREATIRIDGKDIKVAIANGTGNAKK
LLDKVKAGEVEYHFIEVMGCPGGCIMGGGQPIHNPNEMEKVKELRAKAIYEADKNLPIRKSHKNPAIQKLYEEFLGSPLS
EKSHHLLHTHYSKKELYPLVK

Specific function: Ndh-1 Shuttles Electrons From NADH, Via Fmn And Iron- Sulfur (Fe-S) Centers, To Quinones In The Respiratory Chain. The Immediate Electron Acceptor For The Enzyme In This Species Is Believed To Be Ubiquinone. Couples The Redox Reaction To Proton Translocat

COG id: COG4624

COG function: function code R; Iron only hydrogenase large subunit, C-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI11968051, Length=416, Percent_Identity=31.4903846153846, Blast_Score=200, Evalue=3e-51,
Organism=Homo sapiens, GI6912524, Length=412, Percent_Identity=27.6699029126214, Blast_Score=166, Evalue=5e-41,
Organism=Homo sapiens, GI84452151, Length=370, Percent_Identity=28.9189189189189, Blast_Score=162, Evalue=1e-39,
Organism=Homo sapiens, GI134284357, Length=370, Percent_Identity=28.9189189189189, Blast_Score=162, Evalue=1e-39,
Organism=Homo sapiens, GI14165461, Length=449, Percent_Identity=27.6169265033408, Blast_Score=149, Evalue=6e-36,
Organism=Homo sapiens, GI33519475, Length=221, Percent_Identity=31.2217194570136, Blast_Score=121, Evalue=2e-27,
Organism=Escherichia coli, GI145693161, Length=216, Percent_Identity=27.7777777777778, Blast_Score=96, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI71995015, Length=409, Percent_Identity=29.0953545232274, Blast_Score=131, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI32566231, Length=242, Percent_Identity=33.0578512396694, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17565758, Length=239, Percent_Identity=33.4728033472803, Blast_Score=122, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI193209088, Length=242, Percent_Identity=33.0578512396694, Blast_Score=120, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6324089, Length=373, Percent_Identity=23.5924932975871, Blast_Score=101, Evalue=3e-22,
Organism=Drosophila melanogaster, GI116007470, Length=407, Percent_Identity=29.7297297297297, Blast_Score=172, Evalue=6e-43,
Organism=Drosophila melanogaster, GI116007466, Length=407, Percent_Identity=29.7297297297297, Blast_Score=172, Evalue=6e-43,
Organism=Drosophila melanogaster, GI116007464, Length=407, Percent_Identity=29.7297297297297, Blast_Score=172, Evalue=7e-43,
Organism=Drosophila melanogaster, GI116007468, Length=407, Percent_Identity=29.7297297297297, Blast_Score=172, Evalue=8e-43,
Organism=Drosophila melanogaster, GI116007462, Length=286, Percent_Identity=33.5664335664336, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24640559, Length=217, Percent_Identity=32.7188940092166, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24640557, Length=217, Percent_Identity=32.7188940092166, Blast_Score=121, Evalue=1e-27,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR009016
- InterPro:   IPR004108
- InterPro:   IPR003149
- InterPro:   IPR013352
- InterPro:   IPR001041 [H]

Pfam domain/function: PF02906 Fe_hyd_lg_C; PF02256 Fe_hyd_SSU [H]

EC number: =1.12.7.2 [H]

Molecular weight: Translated: 64440; Mature: 64440

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKVRVMIDSITVEVPSHYTVLEAAKEAGIDIPTLCYLKEINQIGACRICVVEIEGVRNL
CCCEEEEEEEEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEEEEECCCCCC
QTSCTYPVFDGMKVYTNTPKVREARKLNLELILSNHDRSCLTCIRNTNCELQSLSKKLGV
HHCCCCCCCCCEEEEECCCHHHHHHHCCEEEEEECCCCHHHHHHHCCCCHHHHHHHHCCC
DEIRFEGENIKYSIDNASPSIVRDPNKCVLCRRCVSVCSEVQNVFAIGMVNRGFNTMVAP
CCEEECCCCEEEEECCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCC
SFGRSLKDSPCISCGQCIEVCPVGAIYEKDHTKRVYEALADEKKYVVAQTAPAVRVALGE
HHCCCCCCCCCCCHHHHHHHCCCCHHHCCHHHHHHHHHHHCCCCEEEEECCCEEEEECCH
EFGMPIGSIVTGKMVAALRRMGFDAIFDTNFAADLTIMEEGSELLERLKNGGKLPMITSC
HHCCCHHHHHHHHHHHHHHHCCCHHEECCCCCEEEEEHHHHHHHHHHHHCCCCCCEEECC
SPGWIAFCEKYYPEFIDNLSTCKSPHMMMGALVKSYYAEKKGLNPEDIYIVSIMPCTAKK
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCC
LEIERPEMQHNGIKDVDAVLTTRELARMIKEMGIDFVNLPDEEYDEPLGMSTGAAVIFGA
CCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHCCCEECCCCHHCCCCCCCCCCCEEEEEC
TGGVMEAALRTVADIVEGKDLDKFDYEEVRGLEGVREATIRIDGKDIKVAIANGTGNAKK
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCEEEEEEECCCEEEEEEECCCCHHHH
LLDKVKAGEVEYHFIEVMGCPGGCIMGGGQPIHNPNEMEKVKELRAKAIYEADKNLPIRK
HHHHHHCCCEEEEEEEEEECCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
SHKNPAIQKLYEEFLGSPLSEKSHHLLHTHYSKKELYPLVK
CCCCHHHHHHHHHHHCCCCCCCCCHHHHEECCHHHCCCCCC
>Mature Secondary Structure
MDKVRVMIDSITVEVPSHYTVLEAAKEAGIDIPTLCYLKEINQIGACRICVVEIEGVRNL
CCCEEEEEEEEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEEEEECCCCCC
QTSCTYPVFDGMKVYTNTPKVREARKLNLELILSNHDRSCLTCIRNTNCELQSLSKKLGV
HHCCCCCCCCCEEEEECCCHHHHHHHCCEEEEEECCCCHHHHHHHCCCCHHHHHHHHCCC
DEIRFEGENIKYSIDNASPSIVRDPNKCVLCRRCVSVCSEVQNVFAIGMVNRGFNTMVAP
CCEEECCCCEEEEECCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCC
SFGRSLKDSPCISCGQCIEVCPVGAIYEKDHTKRVYEALADEKKYVVAQTAPAVRVALGE
HHCCCCCCCCCCCHHHHHHHCCCCHHHCCHHHHHHHHHHHCCCCEEEEECCCEEEEECCH
EFGMPIGSIVTGKMVAALRRMGFDAIFDTNFAADLTIMEEGSELLERLKNGGKLPMITSC
HHCCCHHHHHHHHHHHHHHHCCCHHEECCCCCEEEEEHHHHHHHHHHHHCCCCCCEEECC
SPGWIAFCEKYYPEFIDNLSTCKSPHMMMGALVKSYYAEKKGLNPEDIYIVSIMPCTAKK
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCC
LEIERPEMQHNGIKDVDAVLTTRELARMIKEMGIDFVNLPDEEYDEPLGMSTGAAVIFGA
CCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHCCCEECCCCHHCCCCCCCCCCCEEEEEC
TGGVMEAALRTVADIVEGKDLDKFDYEEVRGLEGVREATIRIDGKDIKVAIANGTGNAKK
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCEEEEEEECCCEEEEEEECCCCHHHH
LLDKVKAGEVEYHFIEVMGCPGGCIMGGGQPIHNPNEMEKVKELRAKAIYEADKNLPIRK
HHHHHHCCCEEEEEEEEEECCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
SHKNPAIQKLYEEFLGSPLSEKSHHLLHTHYSKKELYPLVK
CCCCHHHHHHHHHHHCCCCCCCCCHHHHEECCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1911757; 9836629; 10529166 [H]