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The map label for this gene is queF [H]

Identifier: 167040743

GI number: 167040743

Start: 2125864

End: 2126265

Strand: Direct

Name: queF [H]

Synonym: Teth514_2120

Alternate gene names: 167040743

Gene position: 2125864-2126265 (Clockwise)

Preceding gene: 167040742

Following gene: 167040772

Centisome position: 86.51

GC content: 30.85

Gene sequence:

>402_bases
TTGACAGATAAATATAAAGAAAGAAGATTTGACACTTACGGTTATGAAAAGATCGACAAAGAAGTTTTAGAATCCATTGA
ATATGAATACCCTGAAAAAAATACAATTGTAGAATATATAACTAATGAGTTTTCTTCCGTCTGCCCTTGGACAGGATTAC
CTGACAATGCAAAACTCACAATAAGATATATACCTTCTAAAAAATTAGTAGAACTTAAATCTTTAAAGTATTATCTCACC
TCCTATAGAAATGTAGGCATACTGCAAGAACATGCTATAAATAGGATTTTAGATGACTTAGTTGAACTTCTACAGCCAAA
ATTTATGGAAATAATAGGCGAATTTCAAGAAAGAGGTGGAATAGCCACGAGAATTGTGGCAAAATATGAAAAAGAAAAGT
AG

Upstream 100 bases:

>100_bases
TTTATTCCAACTTTCTTAAGCGTAGGATTGGCTGAGACTGTACTTCTTGTAACTGGATATTTTCTGCTTTTTATAATTGA
AAAGAAAGGAGCTGTGAAAT

Downstream 100 bases:

>100_bases
ATATAAATCTGCCCAAAAATTTCCATTGGGCAGCTTTTTTAAATTTGATTCTTCATTCAAATTCTATCTCAAAATGGCCA
TATTTTTTATTATTGTCAAC

Product: 7-cyano-7-deazaguanine reductase

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine reductase; NADPH-dependent nitrile oxidoreductase; PreQ(0) reductase [H]

Number of amino acids: Translated: 133; Mature: 132

Protein sequence:

>133_residues
MTDKYKERRFDTYGYEKIDKEVLESIEYEYPEKNTIVEYITNEFSSVCPWTGLPDNAKLTIRYIPSKKLVELKSLKYYLT
SYRNVGILQEHAINRILDDLVELLQPKFMEIIGEFQERGGIATRIVAKYEKEK

Sequences:

>Translated_133_residues
MTDKYKERRFDTYGYEKIDKEVLESIEYEYPEKNTIVEYITNEFSSVCPWTGLPDNAKLTIRYIPSKKLVELKSLKYYLT
SYRNVGILQEHAINRILDDLVELLQPKFMEIIGEFQERGGIATRIVAKYEKEK
>Mature_132_residues
TDKYKERRFDTYGYEKIDKEVLESIEYEYPEKNTIVEYITNEFSSVCPWTGLPDNAKLTIRYIPSKKLVELKSLKYYLTS
YRNVGILQEHAINRILDDLVELLQPKFMEIIGEFQERGGIATRIVAKYEKEK

Specific function: Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) [H]

COG id: COG0780

COG function: function code R; Enzyme related to GTP cyclohydrolase I

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016856
- InterPro:   IPR020602 [H]

Pfam domain/function: PF01227 GTP_cyclohydroI [H]

EC number: =1.7.1.13 [H]

Molecular weight: Translated: 15785; Mature: 15654

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKYKERRFDTYGYEKIDKEVLESIEYEYPEKNTIVEYITNEFSSVCPWTGLPDNAKLT
CCCCHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEE
IRYIPSKKLVELKSLKYYLTSYRNVGILQEHAINRILDDLVELLQPKFMEIIGEFQERGG
EEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IATRIVAKYEKEK
HHHHHHHHHHCCC
>Mature Secondary Structure 
TDKYKERRFDTYGYEKIDKEVLESIEYEYPEKNTIVEYITNEFSSVCPWTGLPDNAKLT
CCCHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEE
IRYIPSKKLVELKSLKYYLTSYRNVGILQEHAINRILDDLVELLQPKFMEIIGEFQERGG
EEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IATRIVAKYEKEK
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]