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The map label for this gene is engD [H]

Identifier: 167040645

GI number: 167040645

Start: 2031885

End: 2032976

Strand: Direct

Name: engD [H]

Synonym: Teth514_2022

Alternate gene names: 167040645

Gene position: 2031885-2032976 (Clockwise)

Preceding gene: 167040599

Following gene: 167040662

Centisome position: 82.69

GC content: 35.07

Gene sequence:

>1092_bases
ATGGAAATAGGAATTGTTGGACTACCTAATGTCGGCAAAAGCACTTTGTTTAACGCCATTACAAAAGCAGGGGCAGAATG
TGCAAACTATCCTTTTTGTACTATTGAACCAAATGTGGGAATTGTAGCTGTACCAGATAAAAGGCTGGATTTTTTGGCAA
AGATTGAAAATCCGCAAAAAGTTATACCCGCAACTATAAAATTTGTTGACATAGCAGGCCTTGTAAAAGGAGCAAGTAAA
GGAGAGGGTTTAGGAAATAAATTTCTTTCTCATATTAGGGAAGTTGACGCTATATTAAACGTGGTAAGATGTTTTGAAGA
TAGCAATATTGTCCATGTGGAAGGAAGTATTGATCCTATAAGAGATGTTGAAATAATAACTTTAGAGCTTATACTTGCTG
ATATGGAAGTTGTCGAAAGGCGGCTTCAAAAAACATCAAAACTTGCGCGAAATGACAAAAAAGCAGCCTTTGAATTGGAA
ATACTTGAAAAAATAAAAAAAGGATTGAATGAAGGGAAACCTGTAAGGGCTCTTCAATTTACCGAAGAAGAAAAAAGTTT
TGTATGTCAACTTATGTTGCTTACCTCTAAACCCGTCATGTATGTAGCAAATATATCAGAAGAAGATTTAATTTCAGGAG
AAGAAAATCAATATGTAAAGCAACTAAAAGAATATGCTGAAAAAGAAAATTCTCAAGTTTTGGTTATAAGTGCAAAAATT
GAAGAAGAATTAGCTTCTTTAAGTGATGAAGAAAGAAATGAACTTTTGAGAGAATACGGCCTTGCCGAACCCGGCCTTAA
CAACATAATAAGACATGGTTACTCTCTCCTTGGACTTATAACCTTTTTCACTGCTGGACCAAAAGAAGTCCACGCTTGGA
CAATAAAAAAAGGCACAAAAGCACCTCAAGCAGCAGGGAAAATTCATTCAGATTTTGAAAAAGGATTTATAAGGGCAGAA
GTAATCTCTTATGAAGATTTAGTAAAAGCCGGTTCACAGGCAACAGCAAGAGAAATGGGACTTATGAGACTGGAAGGAAA
AGATTATGTGATGCAGGATGGAGATATAGTAGTATTTAGATTTAATGTATAA

Upstream 100 bases:

>100_bases
AAAGTATTATACTAAATTATGGAATTTTTACGAAAAACATTTGAAAAAATTTTGTGAGTAATATATAATGCATATGTAAA
ACTATTGGAGGGAAGATGAA

Downstream 100 bases:

>100_bases
AAATCGCCTTTTAGGCGATTTTTATACATTACTCTTTTTTGTCTATCTTTGGTGTCTCCTCAACTTTATATCCTAAAGCA
GCAATTAAATTATCCAATTT

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MEIGIVGLPNVGKSTLFNAITKAGAECANYPFCTIEPNVGIVAVPDKRLDFLAKIENPQKVIPATIKFVDIAGLVKGASK
GEGLGNKFLSHIREVDAILNVVRCFEDSNIVHVEGSIDPIRDVEIITLELILADMEVVERRLQKTSKLARNDKKAAFELE
ILEKIKKGLNEGKPVRALQFTEEEKSFVCQLMLLTSKPVMYVANISEEDLISGEENQYVKQLKEYAEKENSQVLVISAKI
EEELASLSDEERNELLREYGLAEPGLNNIIRHGYSLLGLITFFTAGPKEVHAWTIKKGTKAPQAAGKIHSDFEKGFIRAE
VISYEDLVKAGSQATAREMGLMRLEGKDYVMQDGDIVVFRFNV

Sequences:

>Translated_363_residues
MEIGIVGLPNVGKSTLFNAITKAGAECANYPFCTIEPNVGIVAVPDKRLDFLAKIENPQKVIPATIKFVDIAGLVKGASK
GEGLGNKFLSHIREVDAILNVVRCFEDSNIVHVEGSIDPIRDVEIITLELILADMEVVERRLQKTSKLARNDKKAAFELE
ILEKIKKGLNEGKPVRALQFTEEEKSFVCQLMLLTSKPVMYVANISEEDLISGEENQYVKQLKEYAEKENSQVLVISAKI
EEELASLSDEERNELLREYGLAEPGLNNIIRHGYSLLGLITFFTAGPKEVHAWTIKKGTKAPQAAGKIHSDFEKGFIRAE
VISYEDLVKAGSQATAREMGLMRLEGKDYVMQDGDIVVFRFNV
>Mature_363_residues
MEIGIVGLPNVGKSTLFNAITKAGAECANYPFCTIEPNVGIVAVPDKRLDFLAKIENPQKVIPATIKFVDIAGLVKGASK
GEGLGNKFLSHIREVDAILNVVRCFEDSNIVHVEGSIDPIRDVEIITLELILADMEVVERRLQKTSKLARNDKKAAFELE
ILEKIKKGLNEGKPVRALQFTEEEKSFVCQLMLLTSKPVMYVANISEEDLISGEENQYVKQLKEYAEKENSQVLVISAKI
EEELASLSDEERNELLREYGLAEPGLNNIIRHGYSLLGLITFFTAGPKEVHAWTIKKGTKAPQAAGKIHSDFEKGFIRAE
VISYEDLVKAGSQATAREMGLMRLEGKDYVMQDGDIVVFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=369, Percent_Identity=49.3224932249323, Blast_Score=348, Evalue=5e-96,
Organism=Homo sapiens, GI58761502, Length=216, Percent_Identity=44.9074074074074, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI24308117, Length=99, Percent_Identity=38.3838383838384, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1787454, Length=364, Percent_Identity=56.5934065934066, Blast_Score=421, Evalue=1e-119,
Organism=Escherichia coli, GI1789574, Length=129, Percent_Identity=32.5581395348837, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17509631, Length=366, Percent_Identity=44.5355191256831, Blast_Score=332, Evalue=2e-91,
Organism=Saccharomyces cerevisiae, GI6319499, Length=370, Percent_Identity=44.0540540540541, Blast_Score=291, Evalue=1e-79,
Organism=Saccharomyces cerevisiae, GI6321773, Length=379, Percent_Identity=37.9947229551451, Blast_Score=251, Evalue=1e-67,
Organism=Saccharomyces cerevisiae, GI6321649, Length=157, Percent_Identity=39.4904458598726, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24640873, Length=368, Percent_Identity=46.7391304347826, Blast_Score=327, Evalue=1e-89,
Organism=Drosophila melanogaster, GI24640877, Length=368, Percent_Identity=46.7391304347826, Blast_Score=327, Evalue=1e-89,
Organism=Drosophila melanogaster, GI24640875, Length=368, Percent_Identity=46.7391304347826, Blast_Score=327, Evalue=1e-89,
Organism=Drosophila melanogaster, GI24640879, Length=327, Percent_Identity=45.2599388379205, Blast_Score=271, Evalue=6e-73,
Organism=Drosophila melanogaster, GI24585318, Length=248, Percent_Identity=26.6129032258064, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 40312; Mature: 40312

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIGIVGLPNVGKSTLFNAITKAGAECANYPFCTIEPNVGIVAVPDKRLDFLAKIENPQK
CCEEEEECCCCCHHHHHHHHHHHCHHHCCCCEEEECCCCCEEECCCHHHHHHHHCCCCCH
VIPATIKFVDIAGLVKGASKGEGLGNKFLSHIREVDAILNVVRCFEDSNIVHVEGSIDPI
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
RDVEIITLELILADMEVVERRLQKTSKLARNDKKAAFELEILEKIKKGLNEGKPVRALQF
CCHHHEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEE
TEEEKSFVCQLMLLTSKPVMYVANISEEDLISGEENQYVKQLKEYAEKENSQVLVISAKI
CHHHHHHHHHHHHHCCCCEEEEECCCHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEEHHH
EEELASLSDEERNELLREYGLAEPGLNNIIRHGYSLLGLITFFTAGPKEVHAWTIKKGTK
HHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCC
APQAAGKIHSDFEKGFIRAEVISYEDLVKAGSQATAREMGLMRLEGKDYVMQDGDIVVFR
CCHHHHHHHHHHHHCCHHHHHHCHHHHHHCCCHHHHHHHCCEEECCCCEEEECCCEEEEE
FNV
ECC
>Mature Secondary Structure
MEIGIVGLPNVGKSTLFNAITKAGAECANYPFCTIEPNVGIVAVPDKRLDFLAKIENPQK
CCEEEEECCCCCHHHHHHHHHHHCHHHCCCCEEEECCCCCEEECCCHHHHHHHHCCCCCH
VIPATIKFVDIAGLVKGASKGEGLGNKFLSHIREVDAILNVVRCFEDSNIVHVEGSIDPI
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
RDVEIITLELILADMEVVERRLQKTSKLARNDKKAAFELEILEKIKKGLNEGKPVRALQF
CCHHHEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEE
TEEEKSFVCQLMLLTSKPVMYVANISEEDLISGEENQYVKQLKEYAEKENSQVLVISAKI
CHHHHHHHHHHHHHCCCCEEEEECCCHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEEHHH
EEELASLSDEERNELLREYGLAEPGLNNIIRHGYSLLGLITFFTAGPKEVHAWTIKKGTK
HHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCC
APQAAGKIHSDFEKGFIRAEVISYEDLVKAGSQATAREMGLMRLEGKDYVMQDGDIVVFR
CCHHHHHHHHHHHHCCHHHHHHCHHHHHHCCCHHHHHHHCCEEECCCCEEEECCCEEEEE
FNV
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]