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The map label for this gene is recG [H]

Identifier: 167040378

GI number: 167040378

Start: 1745164

End: 1747209

Strand: Reverse

Name: recG [H]

Synonym: Teth514_1741

Alternate gene names: 167040378

Gene position: 1747209-1745164 (Counterclockwise)

Preceding gene: 167040379

Following gene: 167040377

Centisome position: 71.1

GC content: 32.75

Gene sequence:

>2046_bases
ATGCCTTTGAATCTGGATATTCAGTACGTAAAAGGAGTTGGACCTAAAAGGGCAAAACTTCTTAAAAAATTGGGAATAAA
CACAGTAGAGGACTTATTATTCTATTTTCCCAAAGATTATGAGAATAGAAGCGATATTTTAAAGATTGAGGACCTAAAAG
TTGGGGAAAAACAAACTTTTAGAGGTTACATCGCAGGTAGCCCGAGAGAAATAAAGACTTCAAAAGTCATCATAACTAAA
GTGCCTGTAAAAGATGGGACAGGTGTAGTAGAATTAGTCTGGTATAATCAGCCTTATATAAAGAATAATTTTAAAATTGG
TGAAGAATATATAATAAACGGCAAATTGCAATTTAAATATGGGCAGTTAATAGTAGAAAATCCTGTTTTAGAAAAAAGTG
AAGATTTTAAATTAAACACTGGAAGGATAGTTCCTATTTATGGGCTTACAGAAGGGTTGACGCAAAATGCTATCAGGAAG
ATAATGTTTAATGCGCTTCATGATTATGTACAGGAAGTGGAAGAGTTTTTTGATGAAGAATTTTTATCTGAAAAAGGATT
AATGGATATAAAGAACGCACTAATTAATATAAATTTCCCCCAAAATGAGGCATATTTAGAACAAGCAAAATACAGATTTA
AATATCAAGAACTTTTTTTGCTGCAAATGGCCTTATTTTTAATGAAAAGGTCTGTCAAAGAAAAAAAAGGAATAAAATTT
GAACAGGCAGATTTAAAGCCTTTTCTTATGGGATTGCCTTTTAAATTGACTTTGGCACAGATAAAAGTTTTAAAAGAAAT
AATTGCAGATATGAATTCTCACAAAGTGATGAATCGCTTAGTGCAGGGAGATGTGGGCTCTGGTAAAACAGTTGTTGCAG
CTTGCAGCATGTACATTGCTGTCAAGAATGGCTATCAAGTGGCAATGATGGCTCCAACGGAGATATTGGCAAAACAGCAT
TATTATACGTTAAAAGAGCTTTTTAGAAATACTGATATAAAAATTGGGCTTTTGTCTGGTAGCATTTCACCTTCTAATAA
AAAAGAAGTATTAGAAAAAATCAAAAATGGAGATTATGATATTGTAGTAGGGACCCATGCACTAATAGAGGATAATGTTA
TTTTTAACAATTTAGGACTTTGTATAACTGATGAGCAACACCGATTTGGTGTGAGACAAAGGGCGCTTTTGACACAAAAA
GGTGAAAATCCCGATGTTTTGGTTATGACAGCTACACCAATTCCTCGGACATTTGCTCTCATTCTTTATGGAGATTTAGA
TATATCAATAATTGACCAATTACCTCCTGGAAGAAAAAAAGTTAAAACATACGTTATTTCTTCTTCTGTGAGAGAAAAAG
CCTACGAGTTTGCAATGAAGGAAGTAAAAAAAGGAAGGCAAGTTTATGTAGTTTGTCCACTAATTGAAGAATCGGATAAA
ATAAATGCGATGTCTGCCGAAATAGTATATAGAGAAATTTATAAAGATGCTTTTAAGGAAGCTAAAGTAGGACTTTTACA
CGGTAAAATGGCGGACAGCGATAAAGAGAAGGTTATGGAAGAGTTTGTAAATGGAAAAATTGATATTTTAGTTTCGACTA
CAGTAATAGAGGTGGGAGTAAATGTACCTAATGCAACAGTGATGATTGTAGAAAATGCAGAAAGATTTGGACTTGCACAG
CTTCACCAATTGAGAGGTAGAGTTGGCAGGTCAGAATTTCAGTCTTACTGTATTTTGATTAGTTATTCTAATTCTGACAT
AGCTAAAAAAAGACTGGGAGTTTTAGCTCAAACTTCTGATGGATTTAAAATTGCAGAAAAAGATTTAGAAATAAGAGGGC
CAGGTGAATTTCTAGGATTAAGACAGCATGGACTTCCTGAATTTAAAATTGCTAACATTTTTGAAGACATAGATGTTTTA
GAGAGAGTGCAAAAAGATGTAGAAGAGTTACTGGAAAAAGACCCTAAACTTGAAAACTATCCAAAGCTAAGAAGTATTTT
ACTTAATCAATTTTATCAAAAATTAGAAGGAATAATATTAAATTAG

Upstream 100 bases:

>100_bases
ATTGAAAAATTCTCTTTCCGTAGATGCAGATGTGGAAATTTATTTTGGAGGTCAGCCGCTTTACTATTATGTTATATCAA
TAGAGTAAAGGTGAAACGAA

Downstream 100 bases:

>100_bases
AGAAGGAGAATAGTAGTATGGAAAAGATAGCAATTGTTACAGATAGCTTGTCTGACATACCTGAGGATTTAGTGAAAACT
TATAGGATATTTATAGTTCC

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 681; Mature: 680

Protein sequence:

>681_residues
MPLNLDIQYVKGVGPKRAKLLKKLGINTVEDLLFYFPKDYENRSDILKIEDLKVGEKQTFRGYIAGSPREIKTSKVIITK
VPVKDGTGVVELVWYNQPYIKNNFKIGEEYIINGKLQFKYGQLIVENPVLEKSEDFKLNTGRIVPIYGLTEGLTQNAIRK
IMFNALHDYVQEVEEFFDEEFLSEKGLMDIKNALININFPQNEAYLEQAKYRFKYQELFLLQMALFLMKRSVKEKKGIKF
EQADLKPFLMGLPFKLTLAQIKVLKEIIADMNSHKVMNRLVQGDVGSGKTVVAACSMYIAVKNGYQVAMMAPTEILAKQH
YYTLKELFRNTDIKIGLLSGSISPSNKKEVLEKIKNGDYDIVVGTHALIEDNVIFNNLGLCITDEQHRFGVRQRALLTQK
GENPDVLVMTATPIPRTFALILYGDLDISIIDQLPPGRKKVKTYVISSSVREKAYEFAMKEVKKGRQVYVVCPLIEESDK
INAMSAEIVYREIYKDAFKEAKVGLLHGKMADSDKEKVMEEFVNGKIDILVSTTVIEVGVNVPNATVMIVENAERFGLAQ
LHQLRGRVGRSEFQSYCILISYSNSDIAKKRLGVLAQTSDGFKIAEKDLEIRGPGEFLGLRQHGLPEFKIANIFEDIDVL
ERVQKDVEELLEKDPKLENYPKLRSILLNQFYQKLEGIILN

Sequences:

>Translated_681_residues
MPLNLDIQYVKGVGPKRAKLLKKLGINTVEDLLFYFPKDYENRSDILKIEDLKVGEKQTFRGYIAGSPREIKTSKVIITK
VPVKDGTGVVELVWYNQPYIKNNFKIGEEYIINGKLQFKYGQLIVENPVLEKSEDFKLNTGRIVPIYGLTEGLTQNAIRK
IMFNALHDYVQEVEEFFDEEFLSEKGLMDIKNALININFPQNEAYLEQAKYRFKYQELFLLQMALFLMKRSVKEKKGIKF
EQADLKPFLMGLPFKLTLAQIKVLKEIIADMNSHKVMNRLVQGDVGSGKTVVAACSMYIAVKNGYQVAMMAPTEILAKQH
YYTLKELFRNTDIKIGLLSGSISPSNKKEVLEKIKNGDYDIVVGTHALIEDNVIFNNLGLCITDEQHRFGVRQRALLTQK
GENPDVLVMTATPIPRTFALILYGDLDISIIDQLPPGRKKVKTYVISSSVREKAYEFAMKEVKKGRQVYVVCPLIEESDK
INAMSAEIVYREIYKDAFKEAKVGLLHGKMADSDKEKVMEEFVNGKIDILVSTTVIEVGVNVPNATVMIVENAERFGLAQ
LHQLRGRVGRSEFQSYCILISYSNSDIAKKRLGVLAQTSDGFKIAEKDLEIRGPGEFLGLRQHGLPEFKIANIFEDIDVL
ERVQKDVEELLEKDPKLENYPKLRSILLNQFYQKLEGIILN
>Mature_680_residues
PLNLDIQYVKGVGPKRAKLLKKLGINTVEDLLFYFPKDYENRSDILKIEDLKVGEKQTFRGYIAGSPREIKTSKVIITKV
PVKDGTGVVELVWYNQPYIKNNFKIGEEYIINGKLQFKYGQLIVENPVLEKSEDFKLNTGRIVPIYGLTEGLTQNAIRKI
MFNALHDYVQEVEEFFDEEFLSEKGLMDIKNALININFPQNEAYLEQAKYRFKYQELFLLQMALFLMKRSVKEKKGIKFE
QADLKPFLMGLPFKLTLAQIKVLKEIIADMNSHKVMNRLVQGDVGSGKTVVAACSMYIAVKNGYQVAMMAPTEILAKQHY
YTLKELFRNTDIKIGLLSGSISPSNKKEVLEKIKNGDYDIVVGTHALIEDNVIFNNLGLCITDEQHRFGVRQRALLTQKG
ENPDVLVMTATPIPRTFALILYGDLDISIIDQLPPGRKKVKTYVISSSVREKAYEFAMKEVKKGRQVYVVCPLIEESDKI
NAMSAEIVYREIYKDAFKEAKVGLLHGKMADSDKEKVMEEFVNGKIDILVSTTVIEVGVNVPNATVMIVENAERFGLAQL
HQLRGRVGRSEFQSYCILISYSNSDIAKKRLGVLAQTSDGFKIAEKDLEIRGPGEFLGLRQHGLPEFKIANIFEDIDVLE
RVQKDVEELLEKDPKLENYPKLRSILLNQFYQKLEGIILN

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=674, Percent_Identity=38.8724035608309, Blast_Score=433, Evalue=1e-122,
Organism=Escherichia coli, GI1787357, Length=405, Percent_Identity=39.7530864197531, Blast_Score=290, Evalue=1e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 77547; Mature: 77416

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLNLDIQYVKGVGPKRAKLLKKLGINTVEDLLFYFPKDYENRSDILKIEDLKVGEKQTF
CCCCCEEHHCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHC
RGYIAGSPREIKTSKVIITKVPVKDGTGVVELVWYNQPYIKNNFKIGEEYIINGKLQFKY
CEEECCCCCEEECCEEEEEEECCCCCCCEEEEEEECCCEECCCCEECCEEEECCEEEEEE
GQLIVENPVLEKSEDFKLNTGRIVPIYGLTEGLTQNAIRKIMFNALHDYVQEVEEFFDEE
CCEEEECCCCCCCCCCEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLSEKGLMDIKNALININFPQNEAYLEQAKYRFKYQELFLLQMALFLMKRSVKEKKGIKF
HHHCCCHHHHHHCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
EQADLKPFLMGLPFKLTLAQIKVLKEIIADMNSHKVMNRLVQGDVGSGKTVVAACSMYIA
ECCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHEEEEE
VKNGYQVAMMAPTEILAKQHYYTLKELFRNTDIKIGLLSGSISPSNKKEVLEKIKNGDYD
EECCEEEEEECCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHCCCCEE
IVVGTHALIEDNVIFNNLGLCITDEQHRFGVRQRALLTQKGENPDVLVMTATPIPRTFAL
EEEECHHHEECCEEEECCCEEEECCHHHHCHHHHHHHHCCCCCCCEEEEECCCCCCEEEE
ILYGDLDISIIDQLPPGRKKVKTYVISSSVREKAYEFAMKEVKKGRQVYVVCPLIEESDK
EEEECCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCC
INAMSAEIVYREIYKDAFKEAKVGLLHGKMADSDKEKVMEEFVNGKIDILVSTTVIEVGV
CCHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHCCEEEEEEEEEEEEEEC
NVPNATVMIVENAERFGLAQLHQLRGRVGRSEFQSYCILISYSNSDIAKKRLGVLAQTSD
CCCCEEEEEEECCCCCCHHHHHHHHHHCCHHHHCCEEEEEEECCCHHHHHHHCEEEECCC
GFKIAEKDLEIRGPGEFLGLRQHGLPEFKIANIFEDIDVLERVQKDVEELLEKDPKLENY
CCEEECCCCEECCCHHHHCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PKLRSILLNQFYQKLEGIILN
HHHHHHHHHHHHHHHCCEECC
>Mature Secondary Structure 
PLNLDIQYVKGVGPKRAKLLKKLGINTVEDLLFYFPKDYENRSDILKIEDLKVGEKQTF
CCCCEEHHCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHC
RGYIAGSPREIKTSKVIITKVPVKDGTGVVELVWYNQPYIKNNFKIGEEYIINGKLQFKY
CEEECCCCCEEECCEEEEEEECCCCCCCEEEEEEECCCEECCCCEECCEEEECCEEEEEE
GQLIVENPVLEKSEDFKLNTGRIVPIYGLTEGLTQNAIRKIMFNALHDYVQEVEEFFDEE
CCEEEECCCCCCCCCCEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLSEKGLMDIKNALININFPQNEAYLEQAKYRFKYQELFLLQMALFLMKRSVKEKKGIKF
HHHCCCHHHHHHCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
EQADLKPFLMGLPFKLTLAQIKVLKEIIADMNSHKVMNRLVQGDVGSGKTVVAACSMYIA
ECCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHEEEEE
VKNGYQVAMMAPTEILAKQHYYTLKELFRNTDIKIGLLSGSISPSNKKEVLEKIKNGDYD
EECCEEEEEECCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHCCCCEE
IVVGTHALIEDNVIFNNLGLCITDEQHRFGVRQRALLTQKGENPDVLVMTATPIPRTFAL
EEEECHHHEECCEEEECCCEEEECCHHHHCHHHHHHHHCCCCCCCEEEEECCCCCCEEEE
ILYGDLDISIIDQLPPGRKKVKTYVISSSVREKAYEFAMKEVKKGRQVYVVCPLIEESDK
EEEECCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCC
INAMSAEIVYREIYKDAFKEAKVGLLHGKMADSDKEKVMEEFVNGKIDILVSTTVIEVGV
CCHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHCCEEEEEEEEEEEEEEC
NVPNATVMIVENAERFGLAQLHQLRGRVGRSEFQSYCILISYSNSDIAKKRLGVLAQTSD
CCCCEEEEEEECCCCCCHHHHHHHHHHCCHHHHCCEEEEEEECCCHHHHHHHCEEEECCC
GFKIAEKDLEIRGPGEFLGLRQHGLPEFKIANIFEDIDVLERVQKDVEELLEKDPKLENY
CCEEECCCCEECCCHHHHCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PKLRSILLNQFYQKLEGIILN
HHHHHHHHHHHHHHHCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]