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The map label for this gene is coaD

Identifier: 167040373

GI number: 167040373

Start: 1742336

End: 1742815

Strand: Reverse

Name: coaD

Synonym: Teth514_1736

Alternate gene names: 167040373

Gene position: 1742815-1742336 (Counterclockwise)

Preceding gene: 167040374

Following gene: 167040372

Centisome position: 70.93

GC content: 32.5

Gene sequence:

>480_bases
ATGAAAACTGCAATTTATCCAGGGAGTTTTGATCCAGTTACCTATGGACACATTGATATTATAGAAAGAGGAGCAAATCT
GTTTGATAAGCTGATTGTAGCTGTGCTTTTAAATCCCTCGAAAAAGCCCTTATTTTCGGTGGAAGAAAGGGTAGAGCTTT
TAAAAGCGGTAACTTATGATATTTCTAATGTAGAGATTGATTATTTTGATGGTTTATTAGTAGATTATGCTAAAAAAGTC
AAAGCTAATGCTATAATAAAAGGCTTAAGAATGGTATCTGACTTTGAATATGAGTTTCAAATGGCACTAATCAACAAAAA
ATTAAATCCTTCTCTTGAGACGATTTTTTTAATGACTAATGCAAAGTATGGATATCTAAGTTCCAGTGTGGTAAAAGAAA
TTGCTCAGTTTGGCGGTTGTCTTTCTGAGTTTGTGCCGGATATTGTGGCTCAAAAATTAATGGAAAAATTTTCAAGATAA

Upstream 100 bases:

>100_bases
ACCATAAAAATGATAAAGTAAGAGAAATGTATGGAAATTTAGTAAAGATAAGAGAAAATAAATATGGGGAGACAATATTA
TCATTTTATAAGGAGGAAAT

Downstream 100 bases:

>100_bases
TTAAAGGGGGGTTTATTTTTGTCAAATTTTGATGGTTTAGAAGTTCTTAATCTTTTAGAAGAATTAGAAGACATTATAGA
AAACAGTTCTTCTATTCCTC

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MKTAIYPGSFDPVTYGHIDIIERGANLFDKLIVAVLLNPSKKPLFSVEERVELLKAVTYDISNVEIDYFDGLLVDYAKKV
KANAIIKGLRMVSDFEYEFQMALINKKLNPSLETIFLMTNAKYGYLSSSVVKEIAQFGGCLSEFVPDIVAQKLMEKFSR

Sequences:

>Translated_159_residues
MKTAIYPGSFDPVTYGHIDIIERGANLFDKLIVAVLLNPSKKPLFSVEERVELLKAVTYDISNVEIDYFDGLLVDYAKKV
KANAIIKGLRMVSDFEYEFQMALINKKLNPSLETIFLMTNAKYGYLSSSVVKEIAQFGGCLSEFVPDIVAQKLMEKFSR
>Mature_159_residues
MKTAIYPGSFDPVTYGHIDIIERGANLFDKLIVAVLLNPSKKPLFSVEERVELLKAVTYDISNVEIDYFDGLLVDYAKKV
KANAIIKGLRMVSDFEYEFQMALINKKLNPSLETIFLMTNAKYGYLSSSVVKEIAQFGGCLSEFVPDIVAQKLMEKFSR

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=157, Percent_Identity=47.1337579617834, Blast_Score=172, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_THEP3 (B0K9Z1)

Other databases:

- EMBL:   CP000924
- RefSeq:   YP_001665290.1
- ProteinModelPortal:   B0K9Z1
- SMR:   B0K9Z1
- GeneID:   5875109
- GenomeReviews:   CP000924_GR
- KEGG:   tpd:Teth39_1300
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- BioCyc:   TPSE340099:TETH39_1300-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 17945; Mature: 17945

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTAIYPGSFDPVTYGHIDIIERGANLFDKLIVAVLLNPSKKPLFSVEERVELLKAVTYD
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
ISNVEIDYFDGLLVDYAKKVKANAIIKGLRMVSDFEYEFQMALINKKLNPSLETIFLMTN
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEC
AKYGYLSSSVVKEIAQFGGCLSEFVPDIVAQKLMEKFSR
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTAIYPGSFDPVTYGHIDIIERGANLFDKLIVAVLLNPSKKPLFSVEERVELLKAVTYD
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
ISNVEIDYFDGLLVDYAKKVKANAIIKGLRMVSDFEYEFQMALINKKLNPSLETIFLMTN
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEC
AKYGYLSSSVVKEIAQFGGCLSEFVPDIVAQKLMEKFSR
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA