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The map label for this gene is fabD [H]

Identifier: 167040361

GI number: 167040361

Start: 1731695

End: 1732624

Strand: Reverse

Name: fabD [H]

Synonym: Teth514_1724

Alternate gene names: 167040361

Gene position: 1732624-1731695 (Counterclockwise)

Preceding gene: 167040362

Following gene: 167040360

Centisome position: 70.51

GC content: 37.42

Gene sequence:

>930_bases
ATGAAAGTAGCTTTTATTTACCCCGGGCAAGGTGCCCAATATGCTGGAATGGGCAAAGAAATATACCAAAAATACCAAGA
GGCAAGAGAAATTTTTGAAAGAGCAGATGAAGCTTTAGGGTTTAGCATATCTAAACTTTGTTTTGAAGGACCAGAAGAAG
AACTTATGAAAACAGAAAATACTCAGCCGGCCATTTTAACGGTTTCTGTTGCTTTAACAAAGGTTTTGCAAAAGAGAGGA
ATAAAGGCTGAGGTTACTGCAGGATTGAGCTTAGGAGAGTATTCCTCTTTAGTATTGGCTGAAGCTTTAGATTTTGAAGA
TGCGGTTCGTTTAGTGAAAAACAGAGGAAAGTATATGCAAGAAGTAGTACCCCAAGGAGTGGGTACTATGGCAGCAATAC
TGGGACTTGAAAATGAAGCAGTAGAAGAGATATGTCGTATTGCATCACAAGTTGGAATAGTAGAACCTGCTAATTATAAC
TGCCCTGGACAATTAGTTATATCTGGAGAAGTAAAAGCTGTGGAAAAAGCTGTCGAGCTAGCCAAAGAAAAAGGTGCAAA
AAGAGCAGTAGTATTGGCAGTAAGTGCTCCTTTCCACTGCAGCATGCTAAAAAAAGCAGGAGAACTTTTGGAAAAGGATC
TAGAAAAAATAGAAATAAAAGAGTTAAAAATTCCTGTAATATCAAATGTAACAGCTAACTATGTTACAAGGGAAGAAGTT
AAAGATTTGCTCATAAAACAGGTGAGTCATCCTGTGCTATGGGAACAATCTGTAAAAAGAATGATTGAAGATGGAGTAGA
TACTTTTGTTGAAATAGGTCCAGGAAAGACTCTTACAGGTTTTGTTAAAAAGATTGACAGAACCAAAGCTGCCTATAATT
TTGAAGATGAGGAGTCTCTTTTAAAGACTCTCTCTGCTTTGGAGGGATAA

Upstream 100 bases:

>100_bases
GGACTTATAAATGATATTAAACCTGTTAAAGAAATAATAGAGGACATAATAAAACAAGCAGAGGAAGTAATTGACAATTT
GAATAAAATGAGGTGAAAAA

Downstream 100 bases:

>100_bases
GTATGGAAACTGAAAGAAAAACTGCTTTTATAACCGGTGGGTCAAGAGGAATAGGACGTGCTATTGCTGTACGTTTAGCA
AAAGATGGATTTAATATTGT

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MKVAFIYPGQGAQYAGMGKEIYQKYQEAREIFERADEALGFSISKLCFEGPEEELMKTENTQPAILTVSVALTKVLQKRG
IKAEVTAGLSLGEYSSLVLAEALDFEDAVRLVKNRGKYMQEVVPQGVGTMAAILGLENEAVEEICRIASQVGIVEPANYN
CPGQLVISGEVKAVEKAVELAKEKGAKRAVVLAVSAPFHCSMLKKAGELLEKDLEKIEIKELKIPVISNVTANYVTREEV
KDLLIKQVSHPVLWEQSVKRMIEDGVDTFVEIGPGKTLTGFVKKIDRTKAAYNFEDEESLLKTLSALEG

Sequences:

>Translated_309_residues
MKVAFIYPGQGAQYAGMGKEIYQKYQEAREIFERADEALGFSISKLCFEGPEEELMKTENTQPAILTVSVALTKVLQKRG
IKAEVTAGLSLGEYSSLVLAEALDFEDAVRLVKNRGKYMQEVVPQGVGTMAAILGLENEAVEEICRIASQVGIVEPANYN
CPGQLVISGEVKAVEKAVELAKEKGAKRAVVLAVSAPFHCSMLKKAGELLEKDLEKIEIKELKIPVISNVTANYVTREEV
KDLLIKQVSHPVLWEQSVKRMIEDGVDTFVEIGPGKTLTGFVKKIDRTKAAYNFEDEESLLKTLSALEG
>Mature_309_residues
MKVAFIYPGQGAQYAGMGKEIYQKYQEAREIFERADEALGFSISKLCFEGPEEELMKTENTQPAILTVSVALTKVLQKRG
IKAEVTAGLSLGEYSSLVLAEALDFEDAVRLVKNRGKYMQEVVPQGVGTMAAILGLENEAVEEICRIASQVGIVEPANYN
CPGQLVISGEVKAVEKAVELAKEKGAKRAVVLAVSAPFHCSMLKKAGELLEKDLEKIEIKELKIPVISNVTANYVTREEV
KDLLIKQVSHPVLWEQSVKRMIEDGVDTFVEIGPGKTLTGFVKKIDRTKAAYNFEDEESLLKTLSALEG

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=302, Percent_Identity=32.7814569536424, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI27477045, Length=109, Percent_Identity=34.8623853211009, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1787334, Length=305, Percent_Identity=44.9180327868852, Blast_Score=251, Evalue=5e-68,
Organism=Caenorhabditis elegans, GI71984332, Length=298, Percent_Identity=32.5503355704698, Blast_Score=133, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17550940, Length=292, Percent_Identity=26.7123287671233, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI212642053, Length=295, Percent_Identity=24.7457627118644, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24665753, Length=308, Percent_Identity=37.6623376623377, Blast_Score=169, Evalue=3e-42,
Organism=Drosophila melanogaster, GI19920632, Length=297, Percent_Identity=24.5791245791246, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI221330659, Length=297, Percent_Identity=24.5791245791246, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 33929; Mature: 33929

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVAFIYPGQGAQYAGMGKEIYQKYQEAREIFERADEALGFSISKLCFEGPEEELMKTEN
CEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHCCC
TQPAILTVSVALTKVLQKRGIKAEVTAGLSLGEYSSLVLAEALDFEDAVRLVKNRGKYMQ
CCCEEEHHHHHHHHHHHHCCCCEEHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHCCHHHH
EVVPQGVGTMAAILGLENEAVEEICRIASQVGIVEPANYNCPGQLVISGEVKAVEKAVEL
HHHHCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCHHHHHHHHHHH
AKEKGAKRAVVLAVSAPFHCSMLKKAGELLEKDLEKIEIKELKIPVISNVTANYVTREEV
HHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHH
KDLLIKQVSHPVLWEQSVKRMIEDGVDTFVEIGPGKTLTGFVKKIDRTKAAYNFEDEESL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHCCCCHHHHH
LKTLSALEG
HHHHHHHCC
>Mature Secondary Structure
MKVAFIYPGQGAQYAGMGKEIYQKYQEAREIFERADEALGFSISKLCFEGPEEELMKTEN
CEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHCCC
TQPAILTVSVALTKVLQKRGIKAEVTAGLSLGEYSSLVLAEALDFEDAVRLVKNRGKYMQ
CCCEEEHHHHHHHHHHHHCCCCEEHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHCCHHHH
EVVPQGVGTMAAILGLENEAVEEICRIASQVGIVEPANYNCPGQLVISGEVKAVEKAVEL
HHHHCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCHHHHHHHHHHH
AKEKGAKRAVVLAVSAPFHCSMLKKAGELLEKDLEKIEIKELKIPVISNVTANYVTREEV
HHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHH
KDLLIKQVSHPVLWEQSVKRMIEDGVDTFVEIGPGKTLTGFVKKIDRTKAAYNFEDEESL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHCCCCHHHHH
LKTLSALEG
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]