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The map label for this gene is trpS [H]

Identifier: 167040341

GI number: 167040341

Start: 1713993

End: 1714976

Strand: Reverse

Name: trpS [H]

Synonym: Teth514_1704

Alternate gene names: 167040341

Gene position: 1714976-1713993 (Counterclockwise)

Preceding gene: 167040342

Following gene: 167040338

Centisome position: 69.79

GC content: 35.26

Gene sequence:

>984_bases
TTGAAAAAAGTTTTTTCAGGAGTACAACCCTCGGGAGATATTCACATAGGTAATTACTTGGGTGCAATGAGACAATTTGT
TGCGCTACAAGATGATTATGAATGCTTTTTTTGTGCCGTTGATTTACATGCTTTAACAGTTCCTCAAGACCCTAAAGTTT
TAAAGGAAAAAACTATTGAATTGGCAGCACTTTACCTTGCAATAGGCTTAGATCCTAAAAAAGTTACCATTTTTATTCAG
TCTCACGTTCCTGCCCATGCAGAATTGGCATGGTTGCTACAATGTATAACCTATTTTGGTGAATTGAGCAGGATGACACA
ATTTAAGGATAAAAGCAAAGGAAAGGAATCTGTTTCAGTTGGACTTTTTACATATCCGGACTTGATGGCAGCAGATATAC
TTTTATACAATACCCATTATGTTCCTGTAGGAGAAGACCAAAAGCAGCACTTAGAACTGACAAGAGACATTGCGCAGCGT
TTTAACAACAGATTTGGTGAAACTTTTGTAGTTCCTGAGCCTATGATTTTAAAACTTGGTGCGAGAATAATGAGTCTTAC
TGACCCTACTAAAAAGATGAGTAAAAGTGACAGTGATCCAAATAACAGAATCAATCTTTTGGACGAGCCTTCTTCAATTA
AGAAAAAGATAATGAAAGCAGTAACTGATTCTGAGAGTGAAATAAGATTGGATTGGGATAATAAGCCAGGAGTCAGCAAC
CTTTTGACTATTTATAGTTTGTTTACAGGCATGGAAATAGAAGAAGTTATAAATAAATTTAACGGACAGGGTTATGGCAC
TTTAAAGAAGGAATTAGCAGAGGTCGTAATAGATAAATTGACTGTTATACAAAAAAATTATAAAGACCTCAGTAGAGATT
ATGTTTTGAAGGTTTTAAAGGAAGGGGCGGAAAGAGCCCAAGCTGTTGCTGAAAAAACTTTGAAAGAAGTAAAAGAAAAG
GTGGGATTGATATTAAAAGATTAA

Upstream 100 bases:

>100_bases
TATGAGGGAATTATTTTAAATTTCATTGCAAATTTTGAAATTTTCTCTTATAATTTTTTTTAAACGACATAAAATACTCA
ATTGAAAAGGAGTTGATAGC

Downstream 100 bases:

>100_bases
AAAGGCGTTGGGGAAATGACTTAGTTTTTCAAAGGCTAATGTATCAGGATTTAAATAAATCTCAATCACGTCAAAGCGAG
GCTGAAAATTTCGAAATTTT

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MKKVFSGVQPSGDIHIGNYLGAMRQFVALQDDYECFFCAVDLHALTVPQDPKVLKEKTIELAALYLAIGLDPKKVTIFIQ
SHVPAHAELAWLLQCITYFGELSRMTQFKDKSKGKESVSVGLFTYPDLMAADILLYNTHYVPVGEDQKQHLELTRDIAQR
FNNRFGETFVVPEPMILKLGARIMSLTDPTKKMSKSDSDPNNRINLLDEPSSIKKKIMKAVTDSESEIRLDWDNKPGVSN
LLTIYSLFTGMEIEEVINKFNGQGYGTLKKELAEVVIDKLTVIQKNYKDLSRDYVLKVLKEGAERAQAVAEKTLKEVKEK
VGLILKD

Sequences:

>Translated_327_residues
MKKVFSGVQPSGDIHIGNYLGAMRQFVALQDDYECFFCAVDLHALTVPQDPKVLKEKTIELAALYLAIGLDPKKVTIFIQ
SHVPAHAELAWLLQCITYFGELSRMTQFKDKSKGKESVSVGLFTYPDLMAADILLYNTHYVPVGEDQKQHLELTRDIAQR
FNNRFGETFVVPEPMILKLGARIMSLTDPTKKMSKSDSDPNNRINLLDEPSSIKKKIMKAVTDSESEIRLDWDNKPGVSN
LLTIYSLFTGMEIEEVINKFNGQGYGTLKKELAEVVIDKLTVIQKNYKDLSRDYVLKVLKEGAERAQAVAEKTLKEVKEK
VGLILKD
>Mature_327_residues
MKKVFSGVQPSGDIHIGNYLGAMRQFVALQDDYECFFCAVDLHALTVPQDPKVLKEKTIELAALYLAIGLDPKKVTIFIQ
SHVPAHAELAWLLQCITYFGELSRMTQFKDKSKGKESVSVGLFTYPDLMAADILLYNTHYVPVGEDQKQHLELTRDIAQR
FNNRFGETFVVPEPMILKLGARIMSLTDPTKKMSKSDSDPNNRINLLDEPSSIKKKIMKAVTDSESEIRLDWDNKPGVSN
LLTIYSLFTGMEIEEVINKFNGQGYGTLKKELAEVVIDKLTVIQKNYKDLSRDYVLKVLKEGAERAQAVAEKTLKEVKEK
VGLILKD

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=327, Percent_Identity=43.1192660550459, Blast_Score=283, Evalue=2e-76,
Organism=Homo sapiens, GI41352700, Length=177, Percent_Identity=50.2824858757062, Blast_Score=194, Evalue=9e-50,
Organism=Escherichia coli, GI1789786, Length=328, Percent_Identity=58.8414634146341, Blast_Score=388, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI71982800, Length=329, Percent_Identity=36.7781155015198, Blast_Score=211, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI71982793, Length=329, Percent_Identity=36.7781155015198, Blast_Score=209, Evalue=1e-54,
Organism=Saccharomyces cerevisiae, GI6320474, Length=347, Percent_Identity=40.9221902017291, Blast_Score=234, Evalue=1e-62,
Organism=Drosophila melanogaster, GI24666151, Length=326, Percent_Identity=43.558282208589, Blast_Score=279, Evalue=2e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 36907; Mature: 36907

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVFSGVQPSGDIHIGNYLGAMRQFVALQDDYECFFCAVDLHALTVPQDPKVLKEKTIE
CCCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCEEEEEEEHEEEECCCCCHHHHHHHHH
LAALYLAIGLDPKKVTIFIQSHVPAHAELAWLLQCITYFGELSRMTQFKDKSKGKESVSV
HHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
GLFTYPDLMAADILLYNTHYVPVGEDQKQHLELTRDIAQRFNNRFGETFVVPEPMILKLG
EEEECCHHHHHHHHEEECEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHH
ARIMSLTDPTKKMSKSDSDPNNRINLLDEPSSIKKKIMKAVTDSESEIRLDWDNKPGVSN
HHHHHCCCHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHH
LLTIYSLFTGMEIEEVINKFNGQGYGTLKKELAEVVIDKLTVIQKNYKDLSRDYVLKVLK
HHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGAERAQAVAEKTLKEVKEKVGLILKD
HHHHHHHHHHHHHHHHHHHHHCCEECC
>Mature Secondary Structure
MKKVFSGVQPSGDIHIGNYLGAMRQFVALQDDYECFFCAVDLHALTVPQDPKVLKEKTIE
CCCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCEEEEEEEHEEEECCCCCHHHHHHHHH
LAALYLAIGLDPKKVTIFIQSHVPAHAELAWLLQCITYFGELSRMTQFKDKSKGKESVSV
HHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
GLFTYPDLMAADILLYNTHYVPVGEDQKQHLELTRDIAQRFNNRFGETFVVPEPMILKLG
EEEECCHHHHHHHHEEECEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHH
ARIMSLTDPTKKMSKSDSDPNNRINLLDEPSSIKKKIMKAVTDSESEIRLDWDNKPGVSN
HHHHHCCCHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHH
LLTIYSLFTGMEIEEVINKFNGQGYGTLKKELAEVVIDKLTVIQKNYKDLSRDYVLKVLK
HHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGAERAQAVAEKTLKEVKEKVGLILKD
HHHHHHHHHHHHHHHHHHHHHCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]