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The map label for this gene is cheA [H]

Identifier: 167040305

GI number: 167040305

Start: 1682694

End: 1684676

Strand: Reverse

Name: cheA [H]

Synonym: Teth514_1668

Alternate gene names: 167040305

Gene position: 1684676-1682694 (Counterclockwise)

Preceding gene: 167040306

Following gene: 167040304

Centisome position: 68.56

GC content: 31.37

Gene sequence:

>1983_bases
ATGGAAAATAATCAATACATCGATATATTTATTGAAGAATCACAAGAGCATATAGAAAATTTAAATAGCAATTTATTGCT
TTTGGAAAATGACCCTAAAAATAGGCAAATAATCGATGAGATTTTTAGGTCTGCCCATACTTTAAAGGGTATGGCTGCTA
CTATGGGCTTTGAAAACATGAATAAATTAGCTCATAAAATGGAGGATGTATTACAAGAGGTAAAAAATGGCGAATTAAAC
ATTTCTCATCCCATCATGGATATTCTCTTTAAGTGTGTAGATACCTTAAGTGAGATGCTGGATTCAATATCACAAACAGG
AGAAGATAATGTACCTATTGATGAGTTGATGTTTTTACTTTCGGGCGTTAGTTCTAAATCTAAAAATAAAGAGCCTGTTG
TAGAAAAAGAAAATAATGTTTCCAGTAGCGATACATTATTGAACGTATACGAAGAAGATATAATAAGAGAGGCAGTAAAA
GATAATTACAAAGCCTATAAGATAACAGTACATATTGACAAAGGATGTGTTATGAAATCCGCTCGTGCTTTTATAATCTT
TAATAGTTTAGATGAAATAGGAGACATAATAAATTCTTTTCCCTCTGTAGAAGACATTGAAGATGAAAAATTTGAGGAGA
GTTTCACTGTTCACATCATTACAAAAGAGGATAAAGAAAGTATTGAAAAAAGATTACTGTCTATCGCTGAGGTCAACAAG
GTGGAAGTGGAACTAATAAATATTGATTTAAATAAAGAAGGAGAAACATTTGTCAAGGAGGCATCTTTTTCACAATCTCA
AAGTTTTGAGAACATAAAAAAATCTCAAAGCAATAATAAAACTTCAAAAAGTGTAAGAGTAGATATCGACAGATTGGATA
ATTTAATGAATTTAGTAAGTGAACTTATAATCATAAAAACCCGCCTTGAAGGATTAGAGGCAGATAACAGGAACTCTGAA
ACTGCAAGTGCTATTGAATATTTAGAAAGAATAACTACTAATTTACATGATGCTGTTATGAAGGTAAGAATGGTACCGGT
TGAAAGAGTATTCAATAGATTCCCAAGAATGGTAAGGGATTTATCTTACGAGTTAGGCAAAAAAATTATTCTCAATATGT
ATGGACAAGATACAGAAGTAGATAGAACTGTTATAGATGAAATCGGTGACCCTTTAATTCACCTCATAAGAAATTCTATT
GATCATGGTATCGAAATGCCACAAGAAAGGTTGCAAAAAGGGAAACCAGAACAAGGTACTATTAATTTGAGAGCTTATCA
TGAAGGTAATAATGTCATAATAGAAGTTAGTGATGATGGAAGAGGAATTGATATAGAAAAAGTCAAAGCAAAAGCAGTAG
AGAAAGGCATTTACACCGCTGAGCAAGTAAATGACCTTTCTAAAGATAAAATTTTAGACCTTTTATTTAGGCCAGGTTTT
AGCACTACTGACAAAGTTACAGATATTTCTGGCAGAGGCGTAGGATTAGATGTAGTAAAAAATAAAATCGAATCCTTAAA
CGGCTCAATTGAAATATTATCAGAAATAAATAAGGGAACAAAATTTATAATTAAACTTCCTCTTACTTTAGCAATTATAC
AAGCTTTATTAGTAAAAGTAGGAGATGAAAAATTTGCAATTCCCCTTAATTCAATTTCAGAAATAGTTCATAAAAAAGAG
GAAGAAATACACAATGTTCAAGGAAAGGAAGTAGTTCTTTTTAGAGGAAAGGTAATTCCAATAATAAGATTAAATGAAGT
ATTAGAAACCAAAAAGATTTCTAATAATGGAAATTTGGTGTGTGTAATTATCAAAAAAGGCGAAAATTTAGCATGCTGTA
CTGTAGATGAATTAATTGGCCAGCAAGAGATAGTCATAAAACCATTAGGGAAGTATCTTTCTAATGTCAAAGTTATTGCA
GGAGCTACAATATTGGGAGATGGCCAGGTAGCCTTGATTGTCGATGCCAACAATTTGTTTTAA

Upstream 100 bases:

>100_bases
AAAGGAATGCCTTATAACGCTATAAAAACAGGATTTGTTGATAAAATCCTTCCTTTGGATAAAATTCCAGCAGAAATAAT
TGAGAAGGTGAGGGGATTTT

Downstream 100 bases:

>100_bases
CAAGGAGGGAGAATTTTGAGCCTATATGTTATCGCCAAAATTGATGAGGAAGAATATGCAATAAACATAGAAAAAGTGCA
GACTATAGAAAAAGTAATGG

Product: CheA signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 660; Mature: 660

Protein sequence:

>660_residues
MENNQYIDIFIEESQEHIENLNSNLLLLENDPKNRQIIDEIFRSAHTLKGMAATMGFENMNKLAHKMEDVLQEVKNGELN
ISHPIMDILFKCVDTLSEMLDSISQTGEDNVPIDELMFLLSGVSSKSKNKEPVVEKENNVSSSDTLLNVYEEDIIREAVK
DNYKAYKITVHIDKGCVMKSARAFIIFNSLDEIGDIINSFPSVEDIEDEKFEESFTVHIITKEDKESIEKRLLSIAEVNK
VEVELINIDLNKEGETFVKEASFSQSQSFENIKKSQSNNKTSKSVRVDIDRLDNLMNLVSELIIIKTRLEGLEADNRNSE
TASAIEYLERITTNLHDAVMKVRMVPVERVFNRFPRMVRDLSYELGKKIILNMYGQDTEVDRTVIDEIGDPLIHLIRNSI
DHGIEMPQERLQKGKPEQGTINLRAYHEGNNVIIEVSDDGRGIDIEKVKAKAVEKGIYTAEQVNDLSKDKILDLLFRPGF
STTDKVTDISGRGVGLDVVKNKIESLNGSIEILSEINKGTKFIIKLPLTLAIIQALLVKVGDEKFAIPLNSISEIVHKKE
EEIHNVQGKEVVLFRGKVIPIIRLNEVLETKKISNNGNLVCVIIKKGENLACCTVDELIGQQEIVIKPLGKYLSNVKVIA
GATILGDGQVALIVDANNLF

Sequences:

>Translated_660_residues
MENNQYIDIFIEESQEHIENLNSNLLLLENDPKNRQIIDEIFRSAHTLKGMAATMGFENMNKLAHKMEDVLQEVKNGELN
ISHPIMDILFKCVDTLSEMLDSISQTGEDNVPIDELMFLLSGVSSKSKNKEPVVEKENNVSSSDTLLNVYEEDIIREAVK
DNYKAYKITVHIDKGCVMKSARAFIIFNSLDEIGDIINSFPSVEDIEDEKFEESFTVHIITKEDKESIEKRLLSIAEVNK
VEVELINIDLNKEGETFVKEASFSQSQSFENIKKSQSNNKTSKSVRVDIDRLDNLMNLVSELIIIKTRLEGLEADNRNSE
TASAIEYLERITTNLHDAVMKVRMVPVERVFNRFPRMVRDLSYELGKKIILNMYGQDTEVDRTVIDEIGDPLIHLIRNSI
DHGIEMPQERLQKGKPEQGTINLRAYHEGNNVIIEVSDDGRGIDIEKVKAKAVEKGIYTAEQVNDLSKDKILDLLFRPGF
STTDKVTDISGRGVGLDVVKNKIESLNGSIEILSEINKGTKFIIKLPLTLAIIQALLVKVGDEKFAIPLNSISEIVHKKE
EEIHNVQGKEVVLFRGKVIPIIRLNEVLETKKISNNGNLVCVIIKKGENLACCTVDELIGQQEIVIKPLGKYLSNVKVIA
GATILGDGQVALIVDANNLF
>Mature_660_residues
MENNQYIDIFIEESQEHIENLNSNLLLLENDPKNRQIIDEIFRSAHTLKGMAATMGFENMNKLAHKMEDVLQEVKNGELN
ISHPIMDILFKCVDTLSEMLDSISQTGEDNVPIDELMFLLSGVSSKSKNKEPVVEKENNVSSSDTLLNVYEEDIIREAVK
DNYKAYKITVHIDKGCVMKSARAFIIFNSLDEIGDIINSFPSVEDIEDEKFEESFTVHIITKEDKESIEKRLLSIAEVNK
VEVELINIDLNKEGETFVKEASFSQSQSFENIKKSQSNNKTSKSVRVDIDRLDNLMNLVSELIIIKTRLEGLEADNRNSE
TASAIEYLERITTNLHDAVMKVRMVPVERVFNRFPRMVRDLSYELGKKIILNMYGQDTEVDRTVIDEIGDPLIHLIRNSI
DHGIEMPQERLQKGKPEQGTINLRAYHEGNNVIIEVSDDGRGIDIEKVKAKAVEKGIYTAEQVNDLSKDKILDLLFRPGF
STTDKVTDISGRGVGLDVVKNKIESLNGSIEILSEINKGTKFIIKLPLTLAIIQALLVKVGDEKFAIPLNSISEIVHKKE
EEIHNVQGKEVVLFRGKVIPIIRLNEVLETKKISNNGNLVCVIIKKGENLACCTVDELIGQQEIVIKPLGKYLSNVKVIA
GATILGDGQVALIVDANNLF

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Membrane (Potential). Note=It is not known whether CheA is actually membrane bound although CheA has two regions at the C-terminal end with the potential to be transmembrane regions [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=667, Percent_Identity=33.7331334332834, Blast_Score=372, Evalue=1e-104,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR010808 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 74257; Mature: 74257

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENNQYIDIFIEESQEHIENLNSNLLLLENDPKNRQIIDEIFRSAHTLKGMAATMGFENM
CCCCCEEEEEEECCHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCHHHH
NKLAHKMEDVLQEVKNGELNISHPIMDILFKCVDTLSEMLDSISQTGEDNVPIDELMFLL
HHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
SGVSSKSKNKEPVVEKENNVSSSDTLLNVYEEDIIREAVKDNYKAYKITVHIDKGCVMKS
HCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCHHHHC
ARAFIIFNSLDEIGDIINSFPSVEDIEDEKFEESFTVHIITKEDKESIEKRLLSIAEVNK
CCEEEEECCHHHHHHHHHCCCCCCCCCHHHCCCCEEEEEEECCHHHHHHHHHHHHHHCCE
VEVELINIDLNKEGETFVKEASFSQSQSFENIKKSQSNNKTSKSVRVDIDRLDNLMNLVS
EEEEEEEEEECCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHH
ELIIIKTRLEGLEADNRNSETASAIEYLERITTNLHDAVMKVRMVPVERVFNRFPRMVRD
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LSYELGKKIILNMYGQDTEVDRTVIDEIGDPLIHLIRNSIDHGIEMPQERLQKGKPEQGT
HHHHHHHHHHHHCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCE
INLRAYHEGNNVIIEVSDDGRGIDIEKVKAKAVEKGIYTAEQVNDLSKDKILDLLFRPGF
EEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHCCCC
STTDKVTDISGRGVGLDVVKNKIESLNGSIEILSEINKGTKFIIKLPLTLAIIQALLVKV
CCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHC
GDEKFAIPLNSISEIVHKKEEEIHNVQGKEVVLFRGKVIPIIRLNEVLETKKISNNGNLV
CCCCEEEEHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEEEHHHHHHHHHCCCCCCEE
CVIIKKGENLACCTVDELIGQQEIVIKPLGKYLSNVKVIAGATILGDGQVALIVDANNLF
EEEEECCCCEEEEEHHHHHCCCHHHHHHHHHHHCCCEEEECEEEECCCCEEEEEECCCCC
>Mature Secondary Structure
MENNQYIDIFIEESQEHIENLNSNLLLLENDPKNRQIIDEIFRSAHTLKGMAATMGFENM
CCCCCEEEEEEECCHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCHHHH
NKLAHKMEDVLQEVKNGELNISHPIMDILFKCVDTLSEMLDSISQTGEDNVPIDELMFLL
HHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
SGVSSKSKNKEPVVEKENNVSSSDTLLNVYEEDIIREAVKDNYKAYKITVHIDKGCVMKS
HCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCHHHHC
ARAFIIFNSLDEIGDIINSFPSVEDIEDEKFEESFTVHIITKEDKESIEKRLLSIAEVNK
CCEEEEECCHHHHHHHHHCCCCCCCCCHHHCCCCEEEEEEECCHHHHHHHHHHHHHHCCE
VEVELINIDLNKEGETFVKEASFSQSQSFENIKKSQSNNKTSKSVRVDIDRLDNLMNLVS
EEEEEEEEEECCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHH
ELIIIKTRLEGLEADNRNSETASAIEYLERITTNLHDAVMKVRMVPVERVFNRFPRMVRD
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LSYELGKKIILNMYGQDTEVDRTVIDEIGDPLIHLIRNSIDHGIEMPQERLQKGKPEQGT
HHHHHHHHHHHHCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCE
INLRAYHEGNNVIIEVSDDGRGIDIEKVKAKAVEKGIYTAEQVNDLSKDKILDLLFRPGF
EEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHCCCC
STTDKVTDISGRGVGLDVVKNKIESLNGSIEILSEINKGTKFIIKLPLTLAIIQALLVKV
CCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHC
GDEKFAIPLNSISEIVHKKEEEIHNVQGKEVVLFRGKVIPIIRLNEVLETKKISNNGNLV
CCCCEEEEHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEEEHHHHHHHHHCCCCCCEE
CVIIKKGENLACCTVDELIGQQEIVIKPLGKYLSNVKVIAGATILGDGQVALIVDANNLF
EEEEECCCCEEEEEHHHHHCCCHHHHHHHHHHHCCCEEEECEEEECCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1938941; 9384377 [H]