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The map label for this gene is speB [H]

Identifier: 167040219

GI number: 167040219

Start: 1600539

End: 1601405

Strand: Direct

Name: speB [H]

Synonym: Teth514_1581

Alternate gene names: 167040219

Gene position: 1600539-1601405 (Clockwise)

Preceding gene: 167040218

Following gene: 167040220

Centisome position: 65.14

GC content: 34.83

Gene sequence:

>867_bases
ATGATAGAAGGAAAATATTTTGTTGATCCGGGAAAGTTTTTAGGGGCTACTGAAGATTATGAAAAGGCAGAGGTAGTTAT
ACTAGGTTTGCCTATGGATTACACAGTGAGTTTCAAAGCAGGAAGCCGCTTTGGACCTGCTGCCATAAGGCAAGCCTCTT
ATGGTTTAGAATATTATAGTGTGTATTTAGATAGGAGGTTGGAAGATAAGAAATTTTATGATTTAGGAGATTTAGTACTT
CCTTATGGGAATGTGAAAAAGAGTCTAGATTTAATCTCAAAAGCTACAGAAGACATTTTGAAAAGTGGAAAAAAAGGATT
GTTCTTGGGTGGAGAACATTTAGTGACTTATGGAATTTTAAAAGAGTACTTAAAAAAATATGGGGATAACCTTGTAATCC
TTCATTTTGATGCCCATACTGATTTAAGAGAAGAATTTTTCGGTGAAGCTTATTCTCACGCCACAGTAATGAAAAAAGTA
TGGGATATTGCTAAAGGTATTAAAATGTATAATTTTGGGATAAGGTCAGGTGAAAAAGAAGAATTTGAGTTTGCAGAAAA
AAATACCCACATGTTTTTGTATGAAGTAGTTGAACCTTTGAAAGGTGTAATTGATGATATAAAAGATTATCCAATTTATA
TTAGCTGGGATATAGATGTTGTAGACCCTGCTTTTGCACCAGGCACTGGTACACCAGAACCAGGGGGAATAACCACAAAA
GAGGCATTAGAGGCAATTCATATTTTAAAAGATTTAAATGTAGTTGGGATGGATTTGGTGGAAGTCTCGCCTTCTCACGA
TATAGCTGGTATAACCTCTATTTTAGCAGCTAAACTTATAAGGGAATCTATCCTTTCCTTCTTCTAA

Upstream 100 bases:

>100_bases
TCTATTCCAAGAATAGATACTAAATACTATACACCTGAAATTCACAAAGCGGCCTTTGTACTGCCTAAATTTGTGAAGGA
TATTTTTGATGAGGTGTAAT

Downstream 100 bases:

>100_bases
AAATTTTGAGCCTTTTGGCTCTTTTTTTATTTTGTTTCTTTTGAAAAAATAGTATAATATATTATGAGGAGGTATTAATA
TGAGTAATAAAATTAAAATT

Product: putative agmatinase

Products: NA

Alternate protein names: Agmatine ureohydrolase; AUH [H]

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MIEGKYFVDPGKFLGATEDYEKAEVVILGLPMDYTVSFKAGSRFGPAAIRQASYGLEYYSVYLDRRLEDKKFYDLGDLVL
PYGNVKKSLDLISKATEDILKSGKKGLFLGGEHLVTYGILKEYLKKYGDNLVILHFDAHTDLREEFFGEAYSHATVMKKV
WDIAKGIKMYNFGIRSGEKEEFEFAEKNTHMFLYEVVEPLKGVIDDIKDYPIYISWDIDVVDPAFAPGTGTPEPGGITTK
EALEAIHILKDLNVVGMDLVEVSPSHDIAGITSILAAKLIRESILSFF

Sequences:

>Translated_288_residues
MIEGKYFVDPGKFLGATEDYEKAEVVILGLPMDYTVSFKAGSRFGPAAIRQASYGLEYYSVYLDRRLEDKKFYDLGDLVL
PYGNVKKSLDLISKATEDILKSGKKGLFLGGEHLVTYGILKEYLKKYGDNLVILHFDAHTDLREEFFGEAYSHATVMKKV
WDIAKGIKMYNFGIRSGEKEEFEFAEKNTHMFLYEVVEPLKGVIDDIKDYPIYISWDIDVVDPAFAPGTGTPEPGGITTK
EALEAIHILKDLNVVGMDLVEVSPSHDIAGITSILAAKLIRESILSFF
>Mature_288_residues
MIEGKYFVDPGKFLGATEDYEKAEVVILGLPMDYTVSFKAGSRFGPAAIRQASYGLEYYSVYLDRRLEDKKFYDLGDLVL
PYGNVKKSLDLISKATEDILKSGKKGLFLGGEHLVTYGILKEYLKKYGDNLVILHFDAHTDLREEFFGEAYSHATVMKKV
WDIAKGIKMYNFGIRSGEKEEFEFAEKNTHMFLYEVVEPLKGVIDDIKDYPIYISWDIDVVDPAFAPGTGTPEPGGITTK
EALEAIHILKDLNVVGMDLVEVSPSHDIAGITSILAAKLIRESILSFF

Specific function: Catalyzes the formation of putrescine from agmatine [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=279, Percent_Identity=36.2007168458781, Blast_Score=163, Evalue=2e-40,
Organism=Escherichia coli, GI1789306, Length=261, Percent_Identity=36.3984674329502, Blast_Score=160, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.11 [H]

Molecular weight: Translated: 32310; Mature: 32310

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00148 ARGINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEGKYFVDPGKFLGATEDYEKAEVVILGLPMDYTVSFKAGSRFGPAAIRQASYGLEYYS
CCCCCEEECCHHHCCCCCCCCCCEEEEEECCCCEEEEECCCCCCCHHHHHHHHCCHHHHH
VYLDRRLEDKKFYDLGDLVLPYGNVKKSLDLISKATEDILKSGKKGLFLGGEHLVTYGIL
HHHHHHCCCCHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHH
KEYLKKYGDNLVILHFDAHTDLREEFFGEAYSHATVMKKVWDIAKGIKMYNFGIRSGEKE
HHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCHH
EFEFAEKNTHMFLYEVVEPLKGVIDDIKDYPIYISWDIDVVDPAFAPGTGTPEPGGITTK
HHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCHH
EALEAIHILKDLNVVGMDLVEVSPSHDIAGITSILAAKLIRESILSFF
HHHHHHHHHHHCCHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MIEGKYFVDPGKFLGATEDYEKAEVVILGLPMDYTVSFKAGSRFGPAAIRQASYGLEYYS
CCCCCEEECCHHHCCCCCCCCCCEEEEEECCCCEEEEECCCCCCCHHHHHHHHCCHHHHH
VYLDRRLEDKKFYDLGDLVLPYGNVKKSLDLISKATEDILKSGKKGLFLGGEHLVTYGIL
HHHHHHCCCCHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHH
KEYLKKYGDNLVILHFDAHTDLREEFFGEAYSHATVMKKVWDIAKGIKMYNFGIRSGEKE
HHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCHH
EFEFAEKNTHMFLYEVVEPLKGVIDDIKDYPIYISWDIDVVDPAFAPGTGTPEPGGITTK
HHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCHH
EALEAIHILKDLNVVGMDLVEVSPSHDIAGITSILAAKLIRESILSFF
HHHHHHHHHHHCCHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]