Click here to switch to the map view.

The map label for this gene is mhpC [C]

Identifier: 167040041

GI number: 167040041

Start: 1438593

End: 1439183

Strand: Direct

Name: mhpC [C]

Synonym: Teth514_1401

Alternate gene names: 167040041

Gene position: 1438593-1439183 (Clockwise)

Preceding gene: 167040040

Following gene: 167040042

Centisome position: 58.54

GC content: 29.27

Gene sequence:

>591_bases
ATGGTTATAAAAGGTGAGTATGTAAATATAAAAGGCAGTAAAATTCATTATTTAGAAATAGATAAAGAGAGTAGCAAAGA
TACAGTGATATTATTGCATGGCAAAAGATACAATGCTTATGATTGGATAAATTCAGGGATAGCTGAAAATTTATCTAATC
AAGGATTTAAGGTGATATGCTTTGAGTTTCCCGGATATGGTTCTTCCGAAGAGTGCGAGTTAGAAAAGGAAGAGGTTTTA
TTAGAATTTGTAAAAAAATTAAATATATCTTCTTTTCACCTTGTAGCTCCCTCTTTTAGTGGGGAGATATCTATAAAATT
TGCTCTCAAATATGGCGATATGCTTAAAAGCTTGACAATTGTAGATAGCATAAATGTAGATAAATACAAAGAAAAATTAA
ATGAAATATATGTAAAAACATTGATTGTATGGGGGAAGAAAGATGAAATTGCACCCTATGAATTTGCGGAAATATTGAAA
AATAATATTAAAAACAGTACATTGTTTGTGTTTGAAAATTTGGGACATACCTGCTATTTTGATGATGCAAAAAAGTTCTC
TGAGGTGTTGATAAATTTTATAAGAGCATAA

Upstream 100 bases:

>100_bases
ATGTCCCCTAGGATTATGGGGGTTTTTATTTTGGCATAAAACTTGCATAAATACTGAGTATGAGGCAAAAACTACTTAAG
TAAAAATGGAGGTGATTTAA

Downstream 100 bases:

>100_bases
ATTAAAGGGGCTGTCTTTAGGATGGCCTTTTTTTATGTTGACAAATACAAAATTTCGTGTATAATGTATACATGATACCC
CTAAACAGAGGGGGAGTATT

Product: alpha/beta fold family hydrolase/acetyltransferase-like protein

Products: 2-oxopent-4-enoate; succinate [C]

Alternate protein names: Abhydrolase; Alpha/Beta Hydrolase Fold Protein; Carboxylesterase; 2-Hydroxy-6-Oxo-6-Phenylhexa-2 4-Dienoate Hydrolase; Alpha/Beta Hydrolase Fold; Hydrolase Or Acyltransferase; Alpha/Beta Superfamily Hydrolase/Acyltransferase

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MVIKGEYVNIKGSKIHYLEIDKESSKDTVILLHGKRYNAYDWINSGIAENLSNQGFKVICFEFPGYGSSEECELEKEEVL
LEFVKKLNISSFHLVAPSFSGEISIKFALKYGDMLKSLTIVDSINVDKYKEKLNEIYVKTLIVWGKKDEIAPYEFAEILK
NNIKNSTLFVFENLGHTCYFDDAKKFSEVLINFIRA

Sequences:

>Translated_196_residues
MVIKGEYVNIKGSKIHYLEIDKESSKDTVILLHGKRYNAYDWINSGIAENLSNQGFKVICFEFPGYGSSEECELEKEEVL
LEFVKKLNISSFHLVAPSFSGEISIKFALKYGDMLKSLTIVDSINVDKYKEKLNEIYVKTLIVWGKKDEIAPYEFAEILK
NNIKNSTLFVFENLGHTCYFDDAKKFSEVLINFIRA
>Mature_196_residues
MVIKGEYVNIKGSKIHYLEIDKESSKDTVILLHGKRYNAYDWINSGIAENLSNQGFKVICFEFPGYGSSEECELEKEEVL
LEFVKKLNISSFHLVAPSFSGEISIKFALKYGDMLKSLTIVDSINVDKYKEKLNEIYVKTLIVWGKKDEIAPYEFAEILK
NNIKNSTLFVFENLGHTCYFDDAKKFSEVLINFIRA

Specific function: 3-hydroxyphenylpropionate degradation. [C]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI226437571, Length=190, Percent_Identity=26.8421052631579, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI226443152, Length=200, Percent_Identity=28.5, Blast_Score=91, Evalue=5e-19,
Organism=Homo sapiens, GI14249382, Length=200, Percent_Identity=28.5, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17543658, Length=173, Percent_Identity=24.8554913294798, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.7.1.- [C]

Molecular weight: Translated: 22521; Mature: 22521

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIKGEYVNIKGSKIHYLEIDKESSKDTVILLHGKRYNAYDWINSGIAENLSNQGFKVIC
CEECCEEEEEECCEEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEE
FEFPGYGSSEECELEKEEVLLEFVKKLNISSFHLVAPSFSGEISIKFALKYGDMLKSLTI
EECCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEEEEHHHHHHHHHH
VDSINVDKYKEKLNEIYVKTLIVWGKKDEIAPYEFAEILKNNIKNSTLFVFENLGHTCYF
EECCCHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCEEEE
DDAKKFSEVLINFIRA
CCHHHHHHHHHHHHCC
>Mature Secondary Structure
MVIKGEYVNIKGSKIHYLEIDKESSKDTVILLHGKRYNAYDWINSGIAENLSNQGFKVIC
CEECCEEEEEECCEEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEE
FEFPGYGSSEECELEKEEVLLEFVKKLNISSFHLVAPSFSGEISIKFALKYGDMLKSLTI
EECCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEEEEHHHHHHHHHH
VDSINVDKYKEKLNEIYVKTLIVWGKKDEIAPYEFAEILKNNIKNSTLFVFENLGHTCYF
EECCCHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCEEEE
DDAKKFSEVLINFIRA
CCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-hydroxy-6-ketononadienedicarboxylate; H2O [C]

Specific reaction: 2-hydroxy-6-ketononadienedicarboxylate + H2O = 2-oxopent-4-enoate + succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA