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The map label for this gene is glyQS [H]

Identifier: 167039989

GI number: 167039989

Start: 1383580

End: 1384968

Strand: Direct

Name: glyQS [H]

Synonym: Teth514_1348

Alternate gene names: 167039989

Gene position: 1383580-1384968 (Clockwise)

Preceding gene: 167039988

Following gene: 167039990

Centisome position: 56.31

GC content: 34.63

Gene sequence:

>1389_bases
ATGCCACAAGCAGTTACAATGGATAAAATAGTTGCCCTTGCAAAAAACAGAGGATTTGTTTTTCCAGGGTCTGAAATATA
CGGAGGACTTGCTAATACTTGGGATTATGGACCTCTGGGAGTAGAACTTAAAAACAATATTAAAAGGATGTGGTGGAAAA
GATTTATTCAACAAAGTCCTTATAACGTAGGGATTGATTCTGCAATTTTGATGAATCCAGAAGTGTGGGTTGCATCAGGT
CATGTTAGCAGTTTTAGCGATCCTTTAATGGACTGTAAAGAGTGTAAATCAAGATTTAGAGCTGACCAATTGATTGAAGA
CTACATTAAAGAAAAGGGATTAAATATTTCTATTGAAGGTTGGACAAATGAACAAATGATGGAATTTATAAAAGAACATA
AAGTATCTTGTCCAAAATGTGGTGCCCATAATTTTACTGATATTAGGAAGTTTAATCTCATGTTTAAAACCTATCAAGGT
GTTACAGAAGACTCTAAATCAGAAGTGTATTTGCGACCTGAAACCGCACAAGGAATTTTTGTGAACTTTAAAAATGTTCA
AAGGACAACTCGTAAGAAAATACCTTTTGGAATAGGACAAATTGGTAAATCTTTTAGAAATGAAATTACTCCTGGTAATT
TCATATTCAGAACGAGAGAATTTGAACAGATGGAATTAGAATTTTTCTGTAAACCGGGAGAAGATATGGAATGGTTTAGT
TACTGGAGAAAATATTGCATGGATTGGCTTTTAGAATTCGGCTTAAAAGAAGAAAATTTAAGATTTAGAGACCATAAAAA
AGAAGAACTATCTCACTATAGTACTGCCACCACAGACATAGAATATAATTTTCCCTTTGGATGGGGAGAGTTGTGGGGAA
TAGCTAATAGAACAGATTTTGATTTAAGGCAACATATGGAACATTCGGGAGTTGACCTGTCTTATATGGACCCTGTAACA
GGAGAAAAGTACATACCATATTGCATTGAGCCTTCTGTTGGGGTAGATAGGTTAATGTTGGCATTTTTAATAGATGCCTA
TGAAGAAGAAGAGTTAGAAGATGGAGAAACTAGAGTGGTTTTAAGGCTTCATCCTGCTCTTGCTCCCATTAAGGCAGCAG
TGCTTCCATTATCCAAGAAATTATCAGAAAATGCCTATAAGCTTTATGACCAGTTGAGAAATAAATTCGTAGTAGATTAC
GATGAGACAGGAAGCATAGGTAAAAGGTATAGAAGACAGGATGAGATAGGCACGCCTTTCTGTATTACTTATGACTTTGA
TTCGGAAAATGATCACTGTGTAACCATAAGAGATAGAGATACTATGCAACAAGTGAGAATAAAAATTGAAGAAGTAGAGA
AATATCTTGAAGAAAGGTTAAATTTTTAA

Upstream 100 bases:

>100_bases
GTCTCTTTGGTATTCTTAAATAAGTAAAGTTAAAAACCTTTCTTCCCAAAAGGGATGAAGGGTTTTTGCATAATTGCGAG
AGAAAAAGGAGTGTTATTAA

Downstream 100 bases:

>100_bases
GGGAATCAGGATTTTTAACTGATTTCCTTGTTTTTTTATGTTACAATAATTTGTGATATAATAGGAAGGAAACGAAAAAG
AAAGTTGGTTATCTTATAAA

Product: glycyl-tRNA synthetase

Products: NA

Alternate protein names: Glycine--tRNA ligase; GlyRS [H]

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MPQAVTMDKIVALAKNRGFVFPGSEIYGGLANTWDYGPLGVELKNNIKRMWWKRFIQQSPYNVGIDSAILMNPEVWVASG
HVSSFSDPLMDCKECKSRFRADQLIEDYIKEKGLNISIEGWTNEQMMEFIKEHKVSCPKCGAHNFTDIRKFNLMFKTYQG
VTEDSKSEVYLRPETAQGIFVNFKNVQRTTRKKIPFGIGQIGKSFRNEITPGNFIFRTREFEQMELEFFCKPGEDMEWFS
YWRKYCMDWLLEFGLKEENLRFRDHKKEELSHYSTATTDIEYNFPFGWGELWGIANRTDFDLRQHMEHSGVDLSYMDPVT
GEKYIPYCIEPSVGVDRLMLAFLIDAYEEEELEDGETRVVLRLHPALAPIKAAVLPLSKKLSENAYKLYDQLRNKFVVDY
DETGSIGKRYRRQDEIGTPFCITYDFDSENDHCVTIRDRDTMQQVRIKIEEVEKYLEERLNF

Sequences:

>Translated_462_residues
MPQAVTMDKIVALAKNRGFVFPGSEIYGGLANTWDYGPLGVELKNNIKRMWWKRFIQQSPYNVGIDSAILMNPEVWVASG
HVSSFSDPLMDCKECKSRFRADQLIEDYIKEKGLNISIEGWTNEQMMEFIKEHKVSCPKCGAHNFTDIRKFNLMFKTYQG
VTEDSKSEVYLRPETAQGIFVNFKNVQRTTRKKIPFGIGQIGKSFRNEITPGNFIFRTREFEQMELEFFCKPGEDMEWFS
YWRKYCMDWLLEFGLKEENLRFRDHKKEELSHYSTATTDIEYNFPFGWGELWGIANRTDFDLRQHMEHSGVDLSYMDPVT
GEKYIPYCIEPSVGVDRLMLAFLIDAYEEEELEDGETRVVLRLHPALAPIKAAVLPLSKKLSENAYKLYDQLRNKFVVDY
DETGSIGKRYRRQDEIGTPFCITYDFDSENDHCVTIRDRDTMQQVRIKIEEVEKYLEERLNF
>Mature_461_residues
PQAVTMDKIVALAKNRGFVFPGSEIYGGLANTWDYGPLGVELKNNIKRMWWKRFIQQSPYNVGIDSAILMNPEVWVASGH
VSSFSDPLMDCKECKSRFRADQLIEDYIKEKGLNISIEGWTNEQMMEFIKEHKVSCPKCGAHNFTDIRKFNLMFKTYQGV
TEDSKSEVYLRPETAQGIFVNFKNVQRTTRKKIPFGIGQIGKSFRNEITPGNFIFRTREFEQMELEFFCKPGEDMEWFSY
WRKYCMDWLLEFGLKEENLRFRDHKKEELSHYSTATTDIEYNFPFGWGELWGIANRTDFDLRQHMEHSGVDLSYMDPVTG
EKYIPYCIEPSVGVDRLMLAFLIDAYEEEELEDGETRVVLRLHPALAPIKAAVLPLSKKLSENAYKLYDQLRNKFVVDYD
ETGSIGKRYRRQDEIGTPFCITYDFDSENDHCVTIRDRDTMQQVRIKIEEVEKYLEERLNF

Specific function: Catalyzes the attachment of glycine to tRNA(Gly) [H]

COG id: COG0423

COG function: function code J; Glycyl-tRNA synthetase (class II)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI116805340, Length=379, Percent_Identity=30.0791556728232, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI70887790, Length=437, Percent_Identity=23.1121281464531, Blast_Score=90, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17554996, Length=412, Percent_Identity=32.2815533980583, Blast_Score=178, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI32564541, Length=384, Percent_Identity=32.8125, Blast_Score=178, Evalue=5e-45,
Organism=Saccharomyces cerevisiae, GI6325338, Length=366, Percent_Identity=30.8743169398907, Blast_Score=173, Evalue=5e-44,
Organism=Saccharomyces cerevisiae, GI6319597, Length=391, Percent_Identity=29.156010230179, Blast_Score=156, Evalue=6e-39,
Organism=Drosophila melanogaster, GI21357965, Length=384, Percent_Identity=32.03125, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24664462, Length=384, Percent_Identity=32.03125, Blast_Score=186, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR022961
- InterPro:   IPR002315 [H]

Pfam domain/function: PF03129 HGTP_anticodon; PF00587 tRNA-synt_2b [H]

EC number: =6.1.1.14 [H]

Molecular weight: Translated: 54225; Mature: 54094

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQAVTMDKIVALAKNRGFVFPGSEIYGGLANTWDYGPLGVELKNNIKRMWWKRFIQQSP
CCCCCCHHHHHHHHHCCCEECCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
YNVGIDSAILMNPEVWVASGHVSSFSDPLMDCKECKSRFRADQLIEDYIKEKGLNISIEG
CCCCCCCEEEECCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEC
WTNEQMMEFIKEHKVSCPKCGAHNFTDIRKFNLMFKTYQGVTEDSKSEVYLRPETAQGIF
CCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCEEE
VNFKNVQRTTRKKIPFGIGQIGKSFRNEITPGNFIFRTREFEQMELEFFCKPGEDMEWFS
EEEHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEECCCHHHCCEEEEECCCCCCHHHH
YWRKYCMDWLLEFGLKEENLRFRDHKKEELSHYSTATTDIEYNFPFGWGELWGIANRTDF
HHHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHHCCCCCEEEEECCCCHHHHHCCCCCCCH
DLRQHMEHSGVDLSYMDPVTGEKYIPYCIEPSVGVDRLMLAFLIDAYEEEELEDGETRVV
HHHHHHHHCCCCEEECCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEE
LRLHPALAPIKAAVLPLSKKLSENAYKLYDQLRNKFVVDYDETGSIGKRYRRQDEIGTPF
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHCCCCCE
CITYDFDSENDHCVTIRDRDTMQQVRIKIEEVEKYLEERLNF
EEEEECCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PQAVTMDKIVALAKNRGFVFPGSEIYGGLANTWDYGPLGVELKNNIKRMWWKRFIQQSP
CCCCCHHHHHHHHHCCCEECCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
YNVGIDSAILMNPEVWVASGHVSSFSDPLMDCKECKSRFRADQLIEDYIKEKGLNISIEG
CCCCCCCEEEECCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEC
WTNEQMMEFIKEHKVSCPKCGAHNFTDIRKFNLMFKTYQGVTEDSKSEVYLRPETAQGIF
CCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCEEE
VNFKNVQRTTRKKIPFGIGQIGKSFRNEITPGNFIFRTREFEQMELEFFCKPGEDMEWFS
EEEHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEECCCHHHCCEEEEECCCCCCHHHH
YWRKYCMDWLLEFGLKEENLRFRDHKKEELSHYSTATTDIEYNFPFGWGELWGIANRTDF
HHHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHHCCCCCEEEEECCCCHHHHHCCCCCCCH
DLRQHMEHSGVDLSYMDPVTGEKYIPYCIEPSVGVDRLMLAFLIDAYEEEELEDGETRVV
HHHHHHHHCCCCEEECCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEE
LRLHPALAPIKAAVLPLSKKLSENAYKLYDQLRNKFVVDYDETGSIGKRYRRQDEIGTPF
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHCCCCCE
CITYDFDSENDHCVTIRDRDTMQQVRIKIEEVEKYLEERLNF
EEEEECCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]