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The map label for this gene is lspA [H]

Identifier: 167039921

GI number: 167039921

Start: 1316363

End: 1316827

Strand: Direct

Name: lspA [H]

Synonym: Teth514_1277

Alternate gene names: 167039921

Gene position: 1316363-1316827 (Clockwise)

Preceding gene: 167039920

Following gene: 167039922

Centisome position: 53.57

GC content: 32.26

Gene sequence:

>465_bases
ATGTTCTATATTTTTATTATCACAATATTGACAGGGATTGATCAGTGGACTAAATATCTTATAGAAACACAATTAAAACC
GATAGGTGCTATACCCATAGTTAAAGATATATTCCATTTGACTTATGCAAGGAATACAGGAGCAGCTTTTAGCATATTGA
GGGATAAGCAGGCATTTTTAATATTAGTCACAACCATTGTTGTTGGCGCATTAATATACTATTTGATAAAAATATTAAAG
ACAGGAGAAGTAGCCTTTAAGCTATCCTTGGCGATAATTATTGGTGGAGCTTTAGGAAATCTTATCGATAGAGTTAGATT
GAACTATGTAACCGACTTTCTCGATTTCACACTAATTAATTACCCCATATTTAATTTAGCAGACGTATTTGTAGTTTCAG
GAGTTGTCATGCTTTCATATATGCTTTTGTTTAAAGGAGATATGCCCAAAATCTCAAAGATGTGA

Upstream 100 bases:

>100_bases
CAAAAAGTATATAGGACTACATGATTTATTAACCCCTTGATTTATTTCCTCAAAGATAAAATCAAGGGGTATCTGTATTT
AAATTTATAAGGAGGAGAAA

Downstream 100 bases:

>100_bases
AATGGGTTTCTGAAAACGCTAAGAAAAAAGGTGTACACCTTCGTTGAGACAGTAGTATTGAAAAGCGCGTCCAGCGAAGC
TAGCAAATGCTAACAGGTGA

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MFYIFIITILTGIDQWTKYLIETQLKPIGAIPIVKDIFHLTYARNTGAAFSILRDKQAFLILVTTIVVGALIYYLIKILK
TGEVAFKLSLAIIIGGALGNLIDRVRLNYVTDFLDFTLINYPIFNLADVFVVSGVVMLSYMLLFKGDMPKISKM

Sequences:

>Translated_154_residues
MFYIFIITILTGIDQWTKYLIETQLKPIGAIPIVKDIFHLTYARNTGAAFSILRDKQAFLILVTTIVVGALIYYLIKILK
TGEVAFKLSLAIIIGGALGNLIDRVRLNYVTDFLDFTLINYPIFNLADVFVVSGVVMLSYMLLFKGDMPKISKM
>Mature_154_residues
MFYIFIITILTGIDQWTKYLIETQLKPIGAIPIVKDIFHLTYARNTGAAFSILRDKQAFLILVTTIVVGALIYYLIKILK
TGEVAFKLSLAIIIGGALGNLIDRVRLNYVTDFLDFTLINYPIFNLADVFVVSGVVMLSYMLLFKGDMPKISKM

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=160, Percent_Identity=29.375, Blast_Score=67, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 17348; Mature: 17348

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFYIFIITILTGIDQWTKYLIETQLKPIGAIPIVKDIFHLTYARNTGAAFSILRDKQAFL
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCHHHH
ILVTTIVVGALIYYLIKILKTGEVAFKLSLAIIIGGALGNLIDRVRLNYVTDFLDFTLIN
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YPIFNLADVFVVSGVVMLSYMLLFKGDMPKISKM
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MFYIFIITILTGIDQWTKYLIETQLKPIGAIPIVKDIFHLTYARNTGAAFSILRDKQAFL
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCHHHH
ILVTTIVVGALIYYLIKILKTGEVAFKLSLAIIIGGALGNLIDRVRLNYVTDFLDFTLIN
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YPIFNLADVFVVSGVVMLSYMLLFKGDMPKISKM
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]