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The map label for this gene is ygcA [C]

Identifier: 167039842

GI number: 167039842

Start: 1235360

End: 1236724

Strand: Direct

Name: ygcA [C]

Synonym: Teth514_1197

Alternate gene names: 167039842

Gene position: 1235360-1236724 (Clockwise)

Preceding gene: 167039841

Following gene: 167039843

Centisome position: 50.27

GC content: 34.21

Gene sequence:

>1365_bases
TTGTTGCACAACATAAAAGTAGGAGAAAATTATGAGGTATATATTGACAATATGGCTCATGAAGGGCAAGGAGTTGGAAG
AATTGGAGGAGTTGCTACATTTGTAGAAGGAGCATTGACAGGAGAAAAGGTTGTTGCACAAATAGATAAAGTTTATAAAA
ATTACGTTATAAGTCATGTAGTAGAAATATTAGAAAAGTCTCATGATAGAGTAAAGCCTTTATGCCCTTATGCAAATAAA
TGTGGTGGTTGCTCTTTCCAGCATCTAAGTTACGAAGGGCAGTTAAAATACAAAACACAAAAGGTAAAAGACAATTTAGA
AAGAATAGGTAAAGTGTATACTAAAGTTCATGAAATCATAGGAATGAAAGAGCCACAAAGATATAGAAATAAGGCTCAGT
TTCCTGTTGGAATGCTTGATGGTGAAGTAGTGACGGGCTTTTATGCACCTCGTTCTCACGATATTGTACCTATAGAAAGC
TGTATGATACAGGATGAGGTTAGTGATTATATCGCAAGGACTATAAGAAATTGGATTAAAAAATATAACGTTTCTGTATA
TGATGAAAAAGCAGGAAAGGGTTTGATAAGGCATATTGTTACAAGAGTTGGGTTTAAAACAGGAGAAGTTATGGTTATCC
TTGTGGTTAATGGAAAACACATACCCTATAAAGAACAATTAATTGATGCTTTGAAAAAAGAGATAAATGGACTTAAAAGT
GTAGTATTAAATATCAACACAAAAAGAACTAATGTGATTATGGGGGAGGATAATATAACTATTTATGGAAGCGATAATAT
TATTGACTATATCAAGGACATAAAATTCGAGATATCACCTTTATCCTTTTTTCAAGTAAATCCTGTTCAAACAGAGGTTT
TATACGGAAAGGCCCTTGAGTATGCCGATTTAAAGGGAGATGAGACCGTAATAGATGTGTATTGTGGGATAGGTACCATA
TCTTTATTTGCAGCACAGAAGGCTTTTTTTGTCTATGGTATAGAGGCTGTCCACCAAGCAGTGGAAGATGCAAAGAGAAA
TGCTTACATAAATGGCATTAAAAACGTGGAATTTATTTCAGGACAAGCGGAAAAAGTAATGCCTGAGTTAGTTGATAAAG
GAGTCAAAGCAGATGTAGTTATAATAGATCCTCCAAGGAAGGGTTGCGATATACCTGTTTTAGAAGCAATTGTGAATATG
AATCCACAAAAAATTGTATACGTCTCTTGTAATCCTTCTACATTGGCACGAGATTTAAGATATCTTGATGACAAAGGATA
CAAAACCATGGAAGTGCAACCTGTTGATATGTTTCCTTATACGCATCACGTTGAAAGTGTTTGCTTGATTACTAATAAAA
GTTAA

Upstream 100 bases:

>100_bases
ATTTTTTCTTAAAATTATAGTAAACGTTTACATATTTTATAAGAACTCTATGTTTTTTCTCAATATAACGGTATAATAAT
TATGGGAAAAGGAGGCGTTT

Downstream 100 bases:

>100_bases
CAATTTTGATTACTGGAAGTAGAATAAAAATCGTGTTTCCCACTATTTAAAGGCAGTTAGAACTTAGGTTATTGGAAAAT
AAATTAATTGGTTTTAGATG

Product: RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MLHNIKVGENYEVYIDNMAHEGQGVGRIGGVATFVEGALTGEKVVAQIDKVYKNYVISHVVEILEKSHDRVKPLCPYANK
CGGCSFQHLSYEGQLKYKTQKVKDNLERIGKVYTKVHEIIGMKEPQRYRNKAQFPVGMLDGEVVTGFYAPRSHDIVPIES
CMIQDEVSDYIARTIRNWIKKYNVSVYDEKAGKGLIRHIVTRVGFKTGEVMVILVVNGKHIPYKEQLIDALKKEINGLKS
VVLNINTKRTNVIMGEDNITIYGSDNIIDYIKDIKFEISPLSFFQVNPVQTEVLYGKALEYADLKGDETVIDVYCGIGTI
SLFAAQKAFFVYGIEAVHQAVEDAKRNAYINGIKNVEFISGQAEKVMPELVDKGVKADVVIIDPPRKGCDIPVLEAIVNM
NPQKIVYVSCNPSTLARDLRYLDDKGYKTMEVQPVDMFPYTHHVESVCLITNKS

Sequences:

>Translated_454_residues
MLHNIKVGENYEVYIDNMAHEGQGVGRIGGVATFVEGALTGEKVVAQIDKVYKNYVISHVVEILEKSHDRVKPLCPYANK
CGGCSFQHLSYEGQLKYKTQKVKDNLERIGKVYTKVHEIIGMKEPQRYRNKAQFPVGMLDGEVVTGFYAPRSHDIVPIES
CMIQDEVSDYIARTIRNWIKKYNVSVYDEKAGKGLIRHIVTRVGFKTGEVMVILVVNGKHIPYKEQLIDALKKEINGLKS
VVLNINTKRTNVIMGEDNITIYGSDNIIDYIKDIKFEISPLSFFQVNPVQTEVLYGKALEYADLKGDETVIDVYCGIGTI
SLFAAQKAFFVYGIEAVHQAVEDAKRNAYINGIKNVEFISGQAEKVMPELVDKGVKADVVIIDPPRKGCDIPVLEAIVNM
NPQKIVYVSCNPSTLARDLRYLDDKGYKTMEVQPVDMFPYTHHVESVCLITNKS
>Mature_454_residues
MLHNIKVGENYEVYIDNMAHEGQGVGRIGGVATFVEGALTGEKVVAQIDKVYKNYVISHVVEILEKSHDRVKPLCPYANK
CGGCSFQHLSYEGQLKYKTQKVKDNLERIGKVYTKVHEIIGMKEPQRYRNKAQFPVGMLDGEVVTGFYAPRSHDIVPIES
CMIQDEVSDYIARTIRNWIKKYNVSVYDEKAGKGLIRHIVTRVGFKTGEVMVILVVNGKHIPYKEQLIDALKKEINGLKS
VVLNINTKRTNVIMGEDNITIYGSDNIIDYIKDIKFEISPLSFFQVNPVQTEVLYGKALEYADLKGDETVIDVYCGIGTI
SLFAAQKAFFVYGIEAVHQAVEDAKRNAYINGIKNVEFISGQAEKVMPELVDKGVKADVVIIDPPRKGCDIPVLEAIVNM
NPQKIVYVSCNPSTLARDLRYLDDKGYKTMEVQPVDMFPYTHHVESVCLITNKS

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI34222389, Length=350, Percent_Identity=31.4285714285714, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI51173878, Length=350, Percent_Identity=31.4285714285714, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI269784680, Length=421, Percent_Identity=28.5035629453682, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI269784676, Length=421, Percent_Identity=28.5035629453682, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI20149688, Length=421, Percent_Identity=28.5035629453682, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI269784678, Length=362, Percent_Identity=29.2817679558011, Blast_Score=122, Evalue=5e-28,
Organism=Escherichia coli, GI1789148, Length=444, Percent_Identity=30.1801801801802, Blast_Score=178, Evalue=7e-46,
Organism=Escherichia coli, GI1787083, Length=379, Percent_Identity=25.065963060686, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1790403, Length=256, Percent_Identity=28.125, Blast_Score=85, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71997438, Length=162, Percent_Identity=32.0987654320988, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322909, Length=391, Percent_Identity=25.5754475703325, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24666579, Length=414, Percent_Identity=30.1932367149758, Blast_Score=171, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016027
- InterPro:   IPR001566
- InterPro:   IPR002792
- InterPro:   IPR010280 [H]

Pfam domain/function: PF01938 TRAM; PF05958 tRNA_U5-meth_tr [H]

EC number: NA

Molecular weight: Translated: 51055; Mature: 51055

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: PS50926 TRAM ; PS01230 TRMA_1 ; PS01231 TRMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHNIKVGENYEVYIDNMAHEGQGVGRIGGVATFVEGALTGEKVVAQIDKVYKNYVISHV
CCCCEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
VEILEKSHDRVKPLCPYANKCGGCSFQHLSYEGQLKYKTQKVKDNLERIGKVYTKVHEII
HHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
GMKEPQRYRNKAQFPVGMLDGEVVTGFYAPRSHDIVPIESCMIQDEVSDYIARTIRNWIK
CCCCCHHHHCCCCCCEEECCCCEEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHH
KYNVSVYDEKAGKGLIRHIVTRVGFKTGEVMVILVVNGKHIPYKEQLIDALKKEINGLKS
HCCCEEEECCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHE
VVLNINTKRTNVIMGEDNITIYGSDNIIDYIKDIKFEISPLSFFQVNPVQTEVLYGKALE
EEEEECCCCEEEEECCCCEEEEECCCHHHHHHHCEEEECCEEEEEECCCCEEHHHHCHHH
YADLKGDETVIDVYCGIGTISLFAAQKAFFVYGIEAVHQAVEDAKRNAYINGIKNVEFIS
HCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCEEEEC
GQAEKVMPELVDKGVKADVVIIDPPRKGCDIPVLEAIVNMNPQKIVYVSCNPSTLARDLR
CCHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHCCCCCEEEEEECCHHHHHHHHH
YLDDKGYKTMEVQPVDMFPYTHHVESVCLITNKS
HHCCCCCEEEEEEEEECCCCHHCCCEEEEEECCC
>Mature Secondary Structure
MLHNIKVGENYEVYIDNMAHEGQGVGRIGGVATFVEGALTGEKVVAQIDKVYKNYVISHV
CCCCEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
VEILEKSHDRVKPLCPYANKCGGCSFQHLSYEGQLKYKTQKVKDNLERIGKVYTKVHEII
HHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
GMKEPQRYRNKAQFPVGMLDGEVVTGFYAPRSHDIVPIESCMIQDEVSDYIARTIRNWIK
CCCCCHHHHCCCCCCEEECCCCEEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHH
KYNVSVYDEKAGKGLIRHIVTRVGFKTGEVMVILVVNGKHIPYKEQLIDALKKEINGLKS
HCCCEEEECCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHE
VVLNINTKRTNVIMGEDNITIYGSDNIIDYIKDIKFEISPLSFFQVNPVQTEVLYGKALE
EEEEECCCCEEEEECCCCEEEEECCCHHHHHHHCEEEECCEEEEEECCCCEEHHHHCHHH
YADLKGDETVIDVYCGIGTISLFAAQKAFFVYGIEAVHQAVEDAKRNAYINGIKNVEFIS
HCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCEEEEC
GQAEKVMPELVDKGVKADVVIIDPPRKGCDIPVLEAIVNMNPQKIVYVSCNPSTLARDLR
CCHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHCCCCCEEEEEECCHHHHHHHHH
YLDDKGYKTMEVQPVDMFPYTHHVESVCLITNKS
HHCCCCCEEEEEEEEECCCCHHCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]