BacMap

Definition	Thermoanaerobacter sp. X514 chromosome, complete genome.
Accession	NC_010320
Length	2,457,259

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The map label for this gene is copA [H]

Identifier: 167039812

GI number: 167039812

Start: 1204122

End: 1205150

Strand: Direct

Name: copA [H]

Synonym: Teth514_1166

Alternate gene names: 167039812

Gene position: 1204122-1205150 (Clockwise)

Preceding gene: 167039810

Following gene: 167039813

Centisome position: 49.0

GC content: 37.22

Gene sequence:

>1029_bases
ATGCACTTTATTAAATTTTTAAGAAGTGAGACAAATTTATTGTCTTTAAAATTAATTATACGAGGAGGAGAACATCTGCA
GAAAGCAGGAAAAATCACGACAATAGTGCTTGATAAGACTGGGACGATAACAAAAGGAGAACCGGAAGTTACAGACATAG
TAGCTTTTGGAGATTTTACCGAGGATGAGATACTAAAAATAGCGGGAATTGCAGAAAAAAATTCTGAGCACCCATTGGGA
CAAGCAATCGTTAATAAAGCAAAAGAAAAATTCAAAATATTGGAAGACCCTGAGAAATTTGAGGCTATACCAGGCTACGG
TATATGCATTATGATAAATGAAAAAGAGTTTTATATTGGCAATAGAAGGCTCATGGACAAACAAAATATTGATGTAACAT
CAATTGAAGATAAAGTCACAGAACTAGAATCACAAGGTAAAACAGCAATGATATTGGCATCTCGCGACAGCGTTTATGGC
ATTATAGCTGTTGCAGATACCGTAAAGAGTGACTCGGCAAAAGCTATTAAAGAGTTACACGCTATGGGTATTGAAGTATA
CATGATTACAGGAGATAATAAAAGGACTGCTGAGGCAATAGCAAAACAAGTTGGTATAAAAAATGTGCTGGCAGAAGTAT
TGCCAGAACATAAGGCTGAAGAGGTTATGAAACTTCAAAAAATGGGAAAAGTAGTTGCAATGGTGGGAGACGGTATTAAT
GATGCTCCTGCTTTAGCTACAGCGGATGTTGGCATAGCGATAGGTACAGGTACAGATGTGGCGATAGAAACCTCGGATAT
AACGTTGATAAGTGGTAATCTTATGGGTATTGTGACCGCCATAAAATTAAGCAAAGCTACCATGAGAAATATATATCAAA
ATTTATTCTGGGCTTTTGTATACAATACAATCGGCATACCATTTGCCGCAATGGGCCTTTTAACTCCAGCTATAGCAGGA
GGGGCAATGGCATTTAGCTCAGTATCAGTTGTATCAAATGCCTTGAGATTGAGAAGATTTAGGGAATGA

Upstream 100 bases:

>100_bases
CGGCCGCGCCATGAATCCTGCATATTGCGCAATATTACGGATTCATGGCAATAGATAAGATTTTAGACAAGATGAGAATA
TTAAAGATTTCCAGTTATAA

Downstream 100 bases:

>100_bases
GTTTGGAATTGTCCAAACTCATTCTTTCGCTTATTTCTGTTGCTACTTCAGTCATATGACTGATTGGGTTTAATGCTTTG
TTTGAGATGATTATTCCTCC

Product: P-type HAD superfamily ATPase

Products: ADP; Orthophosphate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MHFIKFLRSETNLLSLKLIIRGGEHLQKAGKITTIVLDKTGTITKGEPEVTDIVAFGDFTEDEILKIAGIAEKNSEHPLG
QAIVNKAKEKFKILEDPEKFEAIPGYGICIMINEKEFYIGNRRLMDKQNIDVTSIEDKVTELESQGKTAMILASRDSVYG
IIAVADTVKSDSAKAIKELHAMGIEVYMITGDNKRTAEAIAKQVGIKNVLAEVLPEHKAEEVMKLQKMGKVVAMVGDGIN
DAPALATADVGIAIGTGTDVAIETSDITLISGNLMGIVTAIKLSKATMRNIYQNLFWAFVYNTIGIPFAAMGLLTPAIAG
GAMAFSSVSVVSNALRLRRFRE

Sequences:

>Translated_342_residues
MHFIKFLRSETNLLSLKLIIRGGEHLQKAGKITTIVLDKTGTITKGEPEVTDIVAFGDFTEDEILKIAGIAEKNSEHPLG
QAIVNKAKEKFKILEDPEKFEAIPGYGICIMINEKEFYIGNRRLMDKQNIDVTSIEDKVTELESQGKTAMILASRDSVYG
IIAVADTVKSDSAKAIKELHAMGIEVYMITGDNKRTAEAIAKQVGIKNVLAEVLPEHKAEEVMKLQKMGKVVAMVGDGIN
DAPALATADVGIAIGTGTDVAIETSDITLISGNLMGIVTAIKLSKATMRNIYQNLFWAFVYNTIGIPFAAMGLLTPAIAG
GAMAFSSVSVVSNALRLRRFRE
>Mature_342_residues
MHFIKFLRSETNLLSLKLIIRGGEHLQKAGKITTIVLDKTGTITKGEPEVTDIVAFGDFTEDEILKIAGIAEKNSEHPLG
QAIVNKAKEKFKILEDPEKFEAIPGYGICIMINEKEFYIGNRRLMDKQNIDVTSIEDKVTELESQGKTAMILASRDSVYG
IIAVADTVKSDSAKAIKELHAMGIEVYMITGDNKRTAEAIAKQVGIKNVLAEVLPEHKAEEVMKLQKMGKVVAMVGDGIN
DAPALATADVGIAIGTGTDVAIETSDITLISGNLMGIVTAIKLSKATMRNIYQNLFWAFVYNTIGIPFAAMGLLTPAIAG
GAMAFSSVSVVSNALRLRRFRE

Specific function: Involved in copper export [H]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 HMA domains [H]

Homologues:

Organism=Homo sapiens, GI55743073, Length=340, Percent_Identity=43.2352941176471, Blast_Score=258, Evalue=8e-69,
Organism=Homo sapiens, GI55743071, Length=340, Percent_Identity=43.2352941176471, Blast_Score=258, Evalue=8e-69,
Organism=Homo sapiens, GI115529486, Length=357, Percent_Identity=40.8963585434174, Blast_Score=247, Evalue=1e-65,
Organism=Homo sapiens, GI28373103, Length=165, Percent_Identity=33.9393939393939, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI28373113, Length=165, Percent_Identity=33.9393939393939, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI28373107, Length=165, Percent_Identity=33.9393939393939, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI28373109, Length=165, Percent_Identity=33.9393939393939, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI28373115, Length=165, Percent_Identity=33.9393939393939, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI28373111, Length=165, Percent_Identity=33.9393939393939, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI28373105, Length=165, Percent_Identity=33.9393939393939, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI209413709, Length=165, Percent_Identity=34.5454545454545, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI24638454, Length=165, Percent_Identity=34.5454545454545, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI4502285, Length=165, Percent_Identity=34.5454545454545, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI48762685, Length=231, Percent_Identity=31.1688311688312, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI48762687, Length=231, Percent_Identity=31.1688311688312, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI48762689, Length=231, Percent_Identity=31.1688311688312, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI48762691, Length=231, Percent_Identity=31.1688311688312, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI10835220, Length=165, Percent_Identity=33.9393939393939, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI27886529, Length=165, Percent_Identity=33.9393939393939, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI118498343, Length=205, Percent_Identity=31.219512195122, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI310128958, Length=159, Percent_Identity=34.5911949685535, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4502271, Length=204, Percent_Identity=28.4313725490196, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI153946397, Length=204, Percent_Identity=27.4509803921569, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI21361181, Length=204, Percent_Identity=26.9607843137255, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI237681109, Length=204, Percent_Identity=26.9607843137255, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI237681111, Length=204, Percent_Identity=26.9607843137255, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI22748667, Length=204, Percent_Identity=26.4705882352941, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI51944966, Length=221, Percent_Identity=24.8868778280543, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI83700225, Length=221, Percent_Identity=26.2443438914027, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI297374799, Length=221, Percent_Identity=26.2443438914027, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1786691, Length=333, Percent_Identity=45.6456456456456, Blast_Score=276, Evalue=2e-75,
Organism=Escherichia coli, GI1789879, Length=322, Percent_Identity=39.7515527950311, Blast_Score=207, Evalue=9e-55,
Organism=Escherichia coli, GI1786914, Length=291, Percent_Identity=32.6460481099656, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI2367363, Length=188, Percent_Identity=31.9148936170213, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17556548, Length=358, Percent_Identity=37.4301675977654, Blast_Score=205, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17554158, Length=187, Percent_Identity=32.0855614973262, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI71988506, Length=187, Percent_Identity=32.0855614973262, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI193210130, Length=187, Percent_Identity=32.0855614973262, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17557486, Length=184, Percent_Identity=34.2391304347826, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17557770, Length=184, Percent_Identity=33.1521739130435, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI32566766, Length=190, Percent_Identity=32.1052631578947, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI193203356, Length=183, Percent_Identity=31.6939890710383, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI193203354, Length=183, Percent_Identity=31.6939890710383, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71997275, Length=207, Percent_Identity=32.3671497584541, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71997262, Length=207, Percent_Identity=32.3671497584541, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71997269, Length=184, Percent_Identity=33.695652173913, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17541776, Length=199, Percent_Identity=32.1608040201005, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17559224, Length=228, Percent_Identity=26.3157894736842, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17531459, Length=108, Percent_Identity=37.037037037037, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320475, Length=341, Percent_Identity=39.5894428152493, Blast_Score=188, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6319772, Length=343, Percent_Identity=26.8221574344023, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6321271, Length=174, Percent_Identity=38.5057471264368, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6321430, Length=321, Percent_Identity=27.7258566978193, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6325221, Length=321, Percent_Identity=28.3489096573209, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6321432, Length=160, Percent_Identity=36.25, Blast_Score=90, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6320243, Length=195, Percent_Identity=31.7948717948718, Blast_Score=90, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6320244, Length=195, Percent_Identity=31.7948717948718, Blast_Score=90, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6320245, Length=195, Percent_Identity=31.2820512820513, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI221329854, Length=213, Percent_Identity=47.4178403755869, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24762455, Length=165, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24762453, Length=165, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24762447, Length=165, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24762457, Length=165, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24762449, Length=165, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24762445, Length=165, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24762451, Length=165, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI17136664, Length=165, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24668704, Length=166, Percent_Identity=34.3373493975904, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI281366617, Length=166, Percent_Identity=34.3373493975904, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24668708, Length=166, Percent_Identity=34.3373493975904, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24668696, Length=166, Percent_Identity=34.3373493975904, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI161085803, Length=166, Percent_Identity=34.3373493975904, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281366676, Length=229, Percent_Identity=25.3275109170306, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24648582, Length=233, Percent_Identity=24.4635193133047, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI45553437, Length=210, Percent_Identity=26.1904761904762, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI45553435, Length=210, Percent_Identity=26.1904761904762, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI45553439, Length=210, Percent_Identity=26.1904761904762, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI281362164, Length=210, Percent_Identity=26.1904761904762, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI45553441, Length=210, Percent_Identity=26.1904761904762, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24648580, Length=210, Percent_Identity=26.1904761904762, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24648578, Length=210, Percent_Identity=26.1904761904762, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24648576, Length=210, Percent_Identity=26.1904761904762, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006403
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR017969
- InterPro:   IPR006121 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00403 HMA; PF00702 Hydrolase [H]

EC number: 3.6.3.4 [C]

Molecular weight: Translated: 37074; Mature: 37074

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00154 ATPASE_E1_E2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFIKFLRSETNLLSLKLIIRGGEHLQKAGKITTIVLDKTGTITKGEPEVTDIVAFGDFT
CHHHHHHHCCCCEEEEEEEEECCHHHHHCCCEEEEEEECCCCCCCCCCCCEEEEEECCCC
EDEILKIAGIAEKNSEHPLGQAIVNKAKEKFKILEDPEKFEAIPGYGICIMINEKEFYIG
HHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCEEEEEECCCEEEEC
NRRLMDKQNIDVTSIEDKVTELESQGKTAMILASRDSVYGIIAVADTVKSDSAKAIKELH
CCEECCCCCCCEEHHHHHHHHHHHCCCEEEEEEECCCEEEEEEEEECCCCCHHHHHHHHH
AMGIEVYMITGDNKRTAEAIAKQVGIKNVLAEVLPEHKAEEVMKLQKMGKVVAMVGDGIN
HCCEEEEEEECCCCHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHHCCEEEEECCCCC
DAPALATADVGIAIGTGTDVAIETSDITLISGNLMGIVTAIKLSKATMRNIYQNLFWAFV
CCCCEEECCCCEEEECCCCEEEEECCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
YNTIGIPFAAMGLLTPAIAGGAMAFSSVSVVSNALRLRRFRE
HHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHFIKFLRSETNLLSLKLIIRGGEHLQKAGKITTIVLDKTGTITKGEPEVTDIVAFGDFT
CHHHHHHHCCCCEEEEEEEEECCHHHHHCCCEEEEEEECCCCCCCCCCCCEEEEEECCCC
EDEILKIAGIAEKNSEHPLGQAIVNKAKEKFKILEDPEKFEAIPGYGICIMINEKEFYIG
HHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCEEEEEECCCEEEEC
NRRLMDKQNIDVTSIEDKVTELESQGKTAMILASRDSVYGIIAVADTVKSDSAKAIKELH
CCEECCCCCCCEEHHHHHHHHHHHCCCEEEEEEECCCEEEEEEEEECCCCCHHHHHHHHH
AMGIEVYMITGDNKRTAEAIAKQVGIKNVLAEVLPEHKAEEVMKLQKMGKVVAMVGDGIN
HCCEEEEEEECCCCHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHHCCEEEEECCCCC
DAPALATADVGIAIGTGTDVAIETSDITLISGNLMGIVTAIKLSKATMRNIYQNLFWAFV
CCCCEEECCCCEEEECCCCEEEEECCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
YNTIGIPFAAMGLLTPAIAGGAMAFSSVSVVSNALRLRRFRE
HHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA