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The map label for this gene is spoVD [H]

Identifier: 167039761

GI number: 167039761

Start: 1155145

End: 1156806

Strand: Reverse

Name: spoVD [H]

Synonym: Teth514_1112

Alternate gene names: 167039761

Gene position: 1156806-1155145 (Counterclockwise)

Preceding gene: 167039773

Following gene: 167039757

Centisome position: 47.08

GC content: 35.62

Gene sequence:

>1662_bases
TTGACATCATATGTAAAAAAACGAACATTTACCATATTTATCTTTTTTACTATTATGATTTTCGCCCTTATCGTAAGGCT
TATATGGATACAGGGTATAAACTCTGAAAAACTTGCCATGGCAGTCGAAAGGCAAAGTACTGCTGATATCATATTAAAGC
CTCAACGGGGCAATATTTATGATGTAAACGGGAATATCCTTGCCTGTAATGTTCCAGCAGGAGATGTATTTGCGGCTCCT
AAATTTATAAAAAATCCAGAAAAAGCTTCAGAAGAACTCTATAAATACTTAAATATGGACAAAGACTCGCTTTATAAAAT
TCTTTCAAATAAAAACTCAGAGTGGGCTGTACTTGGCAGGTCCATTCCTCTTGAAAATATAAATAAAATAAAAAGTCTTA
ACATACCAGGCATATATGTAGAAGATACTTTTATGAGAAATTATCCCAACGACAAAATGCTATCACAAGTATTAGGTTTT
GCAGGAATTGATGGTAATGGTTTGTATGGCCTTGAATACTCTTTAGATAAATACTTGGGTGGTGTACCTGGCCGTGAAAT
CTCTCTTGTAGATAGAGAAGGTAGAAAAGTAGGAGTTCCAAAGTTTTACAAAGAACCTACAAACGGTGATAATATTGTCC
TCACAATTGATTCTGTAATACAAAGTTATACAGAAAAAGCTATAAAAAAAGCATATGAAAAATATAAACCAGAAGATGGC
ATAACAGCAATAGTTATGAATCCAAAAACTGGTGAAATACTTGCCATGGCTAATTTGCCCGATTTTGACCCAAATAATTG
GCAAAATGTGCCTTCAAAGGAATACTGGTCAAACCCGGCAGTGTCAAGTACTTACGAACCCGCTTCAGTATTTAAAGTAA
TAACCGCTTCTGCAGCATTAGAATCAGCTGTAGTTACACCAGACGAAAAATTCTACGACCCTGGATATTATATAGTCTCT
GGTAAAAAAATTAGAAGTTGGAAAGCTTTGGGAGATATAACTTTTTCGCAAGCTATTGAAAAATCAAGTAATACAGTTTT
TGTCCAAGTAGTAGAACGATTAGGTGTCGATGCCTTTTATAAATACATACAAGCTTTTGGTTTTGGTACTCCAACAGGAA
TTGAGCTTCCTGGAGAAGCCAGTGGAATGATCTTGCCAAAGTCAAAGATATATCCTGTCGACCTCGCTACTATGTCTTTT
GGTCAAGGAATCGCTGTAACTCCAATCCAAATGATTACAGCTTTTTCAGCCGTGATAAACGGTGGAAACCTCATGGTTCC
ACATATTGTAAAATATATCGAAAACGGCGATAAAAAAATTAAAGAATATAAGCCTCAAATAGTTAGACAAGTTATCTCTA
AAAAAACATCCGATACAATGAGACATATACTTGAAAAAACAGTAACAGAGGGTACCGGCCAAGCAGCAAAAGTACCTGGC
TATACAGTAGGTGGAAAAACAGGTACAACGGAAAATTATGCTCCAGGGAAATACGTAGCATCATTTGCTGGATTTGCACC
AGTTGAAAACCCAAAAATTGCAGTATTAGTTCTTGTTAAAAATCCAACACAAAATGGTCATATGGGAGGAGAAGTAGCCG
CGCCAATAGCACAAGAAATATTAAGAGATACTCTTAGGTATTATGACACAGTAAAAAAGTAA

Upstream 100 bases:

>100_bases
CAAAAACATTTCTATACTTTTATTTAATTAAATTGCAAAATATCTATGGTATAATTATATTGGATAAACAAAATCTTTAT
AAAAAGGGGTTAGAATAAAA

Downstream 100 bases:

>100_bases
AAAAATAATAATACCCGTTATTTTTAGTGCACCAACTGACTTACACTGTTTTTTATTTCCTCTGTTATATCAAAGGCATT
TTTGTTATTTCCTATTCCTT

Product: peptidoglycan glycosyltransferase

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein [H]

Number of amino acids: Translated: 553; Mature: 552

Protein sequence:

>553_residues
MTSYVKKRTFTIFIFFTIMIFALIVRLIWIQGINSEKLAMAVERQSTADIILKPQRGNIYDVNGNILACNVPAGDVFAAP
KFIKNPEKASEELYKYLNMDKDSLYKILSNKNSEWAVLGRSIPLENINKIKSLNIPGIYVEDTFMRNYPNDKMLSQVLGF
AGIDGNGLYGLEYSLDKYLGGVPGREISLVDREGRKVGVPKFYKEPTNGDNIVLTIDSVIQSYTEKAIKKAYEKYKPEDG
ITAIVMNPKTGEILAMANLPDFDPNNWQNVPSKEYWSNPAVSSTYEPASVFKVITASAALESAVVTPDEKFYDPGYYIVS
GKKIRSWKALGDITFSQAIEKSSNTVFVQVVERLGVDAFYKYIQAFGFGTPTGIELPGEASGMILPKSKIYPVDLATMSF
GQGIAVTPIQMITAFSAVINGGNLMVPHIVKYIENGDKKIKEYKPQIVRQVISKKTSDTMRHILEKTVTEGTGQAAKVPG
YTVGGKTGTTENYAPGKYVASFAGFAPVENPKIAVLVLVKNPTQNGHMGGEVAAPIAQEILRDTLRYYDTVKK

Sequences:

>Translated_553_residues
MTSYVKKRTFTIFIFFTIMIFALIVRLIWIQGINSEKLAMAVERQSTADIILKPQRGNIYDVNGNILACNVPAGDVFAAP
KFIKNPEKASEELYKYLNMDKDSLYKILSNKNSEWAVLGRSIPLENINKIKSLNIPGIYVEDTFMRNYPNDKMLSQVLGF
AGIDGNGLYGLEYSLDKYLGGVPGREISLVDREGRKVGVPKFYKEPTNGDNIVLTIDSVIQSYTEKAIKKAYEKYKPEDG
ITAIVMNPKTGEILAMANLPDFDPNNWQNVPSKEYWSNPAVSSTYEPASVFKVITASAALESAVVTPDEKFYDPGYYIVS
GKKIRSWKALGDITFSQAIEKSSNTVFVQVVERLGVDAFYKYIQAFGFGTPTGIELPGEASGMILPKSKIYPVDLATMSF
GQGIAVTPIQMITAFSAVINGGNLMVPHIVKYIENGDKKIKEYKPQIVRQVISKKTSDTMRHILEKTVTEGTGQAAKVPG
YTVGGKTGTTENYAPGKYVASFAGFAPVENPKIAVLVLVKNPTQNGHMGGEVAAPIAQEILRDTLRYYDTVKK
>Mature_552_residues
TSYVKKRTFTIFIFFTIMIFALIVRLIWIQGINSEKLAMAVERQSTADIILKPQRGNIYDVNGNILACNVPAGDVFAAPK
FIKNPEKASEELYKYLNMDKDSLYKILSNKNSEWAVLGRSIPLENINKIKSLNIPGIYVEDTFMRNYPNDKMLSQVLGFA
GIDGNGLYGLEYSLDKYLGGVPGREISLVDREGRKVGVPKFYKEPTNGDNIVLTIDSVIQSYTEKAIKKAYEKYKPEDGI
TAIVMNPKTGEILAMANLPDFDPNNWQNVPSKEYWSNPAVSSTYEPASVFKVITASAALESAVVTPDEKFYDPGYYIVSG
KKIRSWKALGDITFSQAIEKSSNTVFVQVVERLGVDAFYKYIQAFGFGTPTGIELPGEASGMILPKSKIYPVDLATMSFG
QGIAVTPIQMITAFSAVINGGNLMVPHIVKYIENGDKKIKEYKPQIVRQVISKKTSDTMRHILEKTVTEGTGQAAKVPGY
TVGGKTGTTENYAPGKYVASFAGFAPVENPKIAVLVLVKNPTQNGHMGGEVAAPIAQEILRDTLRYYDTVKK

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=550, Percent_Identity=28.7272727272727, Blast_Score=222, Evalue=4e-59,
Organism=Escherichia coli, GI1786854, Length=615, Percent_Identity=25.0406504065041, Blast_Score=155, Evalue=9e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927 [H]

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 61084; Mature: 60953

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSYVKKRTFTIFIFFTIMIFALIVRLIWIQGINSEKLAMAVERQSTADIILKPQRGNIY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEEHHCCCCCCEEEECCCCCEE
DVNGNILACNVPAGDVFAAPKFIKNPEKASEELYKYLNMDKDSLYKILSNKNSEWAVLGR
ECCCCEEEEECCCCCHHCCCHHHCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEEC
SIPLENINKIKSLNIPGIYVEDTFMRNYPNDKMLSQVLGFAGIDGNGLYGLEYSLDKYLG
CCCHHHHHHHHCCCCCEEEEECHHHHCCCCHHHHHHHHHHCCCCCCCEEEEEEEHHHHHC
GVPGREISLVDREGRKVGVPKFYKEPTNGDNIVLTIDSVIQSYTEKAIKKAYEKYKPEDG
CCCCCEEEEEECCCCEECCCHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCC
ITAIVMNPKTGEILAMANLPDFDPNNWQNVPSKEYWSNPAVSSTYEPASVFKVITASAAL
CEEEEECCCCCCEEEECCCCCCCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHH
ESAVVTPDEKFYDPGYYIVSGKKIRSWKALGDITFSQAIEKSSNTVFVQVVERLGVDAFY
HHHCCCCCHHHCCCCEEEEECCEEECHHHHHCHHHHHHHHCCCCEEHHHHHHHHCHHHHH
KYIQAFGFGTPTGIELPGEASGMILPKSKIYPVDLATMSFGQGIAVTPIQMITAFSAVIN
HHHHHHCCCCCCCCCCCCCCCCEEECCCCCCEEEEHHHCCCCCCEECHHHHHHHHHHHHC
GGNLMVPHIVKYIENGDKKIKEYKPQIVRQVISKKTSDTMRHILEKTVTEGTGQAAKVPG
CCCEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCC
YTVGGKTGTTENYAPGKYVASFAGFAPVENPKIAVLVLVKNPTQNGHMGGEVAAPIAQEI
EEECCCCCCCCCCCCCHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHH
LRDTLRYYDTVKK
HHHHHHHHHHHCC
>Mature Secondary Structure 
TSYVKKRTFTIFIFFTIMIFALIVRLIWIQGINSEKLAMAVERQSTADIILKPQRGNIY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEEHHCCCCCCEEEECCCCCEE
DVNGNILACNVPAGDVFAAPKFIKNPEKASEELYKYLNMDKDSLYKILSNKNSEWAVLGR
ECCCCEEEEECCCCCHHCCCHHHCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEEC
SIPLENINKIKSLNIPGIYVEDTFMRNYPNDKMLSQVLGFAGIDGNGLYGLEYSLDKYLG
CCCHHHHHHHHCCCCCEEEEECHHHHCCCCHHHHHHHHHHCCCCCCCEEEEEEEHHHHHC
GVPGREISLVDREGRKVGVPKFYKEPTNGDNIVLTIDSVIQSYTEKAIKKAYEKYKPEDG
CCCCCEEEEEECCCCEECCCHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCC
ITAIVMNPKTGEILAMANLPDFDPNNWQNVPSKEYWSNPAVSSTYEPASVFKVITASAAL
CEEEEECCCCCCEEEECCCCCCCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHH
ESAVVTPDEKFYDPGYYIVSGKKIRSWKALGDITFSQAIEKSSNTVFVQVVERLGVDAFY
HHHCCCCCHHHCCCCEEEEECCEEECHHHHHCHHHHHHHHCCCCEEHHHHHHHHCHHHHH
KYIQAFGFGTPTGIELPGEASGMILPKSKIYPVDLATMSFGQGIAVTPIQMITAFSAVIN
HHHHHHCCCCCCCCCCCCCCCCEEECCCCCCEEEEHHHCCCCCCEECHHHHHHHHHHHHC
GGNLMVPHIVKYIENGDKKIKEYKPQIVRQVISKKTSDTMRHILEKTVTEGTGQAAKVPG
CCCEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCC
YTVGGKTGTTENYAPGKYVASFAGFAPVENPKIAVLVLVKNPTQNGHMGGEVAAPIAQEI
EEECCCCCCCCCCCCCHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHH
LRDTLRYYDTVKK
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954 [H]