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The map label for this gene is lacZ [H]

Identifier: 167039744

GI number: 167039744

Start: 1133220

End: 1135451

Strand: Direct

Name: lacZ [H]

Synonym: Teth514_1095

Alternate gene names: 167039744

Gene position: 1133220-1135451 (Clockwise)

Preceding gene: 167039743

Following gene: 167039745

Centisome position: 46.12

GC content: 33.42

Gene sequence:

>2232_bases
ATGGGTAGAGAGATTTTAAATTTTAATGTAGATTGGCTATATATTCCTGAAGACTTAAATGATGCATATAAACTTGATTT
TGATGAAAGCAATTTTGAATTTGTTAGTCTTCCTCATGCAAACAAGATATTTCCTCATCACTATTTTAAAGAGGAAGATT
ATAGGTTTGTTTCGTGGTATAGAAAGCACTTTAAACTAGATAGCAAATATGAGGGTAAAAAGGTTTATATTCATTTTGAA
GGTGTTATGACTGTTGCGATGGTTTATGTAAATGGCGAATTCGTAGGAGAACATAAAGGAGGATATACCCCTTTTGAATT
TGACATTACAGAATATGTCAAATATGGCGATTTTGAAAATTTAATTGCTGTACAAGTGGATTCAAGAGAACATAAAGATA
TTCCCCCAGAAGGTCATCTTGTAGATTATATGTTGTTTGGTGGAATATACAGAAATGTATGGTTGAAAATTTTAAATGAA
ACTTATATACAAGATGTTTATTTTGTTGTTGATAAATTGCAAGATTCTGTTGCTGAAATTTCAATTACTACAACCATCGA
AGGTAAAGAGGTAAGAAATGCAAAAATATTGACAGAGGTTATAAATAAAGAAGGTGCTGTGTGTTCATCTTCGGTTACTG
ATGTTAAAGACATGCAAAAGGAGATTGTACAGCGAATAAAGATGGAGAATCCATTAACTTGGTATCCAGATCATCCGTAT
TTATATAATGTGTCTGTAAAACTTATTGCAGAGAATGAAATTTTAGATAATTATACTTTTAGAACAGGAATAAGAACTGT
GCATTTTGGAGATGACGGTAAGTTTTATATTAATGGTGAACCTTTAAAATTAAGAGGATTAAACAGACATCAGACTTTTC
CTTATGTTGGCGGTGCTATGCCGGATAGGGTTCAAAGAAAAGATGCAGATATACTAAAGTATGACTTGGGATTAAATTAT
GTTAGGACGTCACATTATCCGCAGGCTGTTTCATTTTTGGATAGATGTGATGAAATAGGCTTGTTAGTTTTTGAAGAGAT
ACCTGGATGGCAGCATATAGGCGATGAAAATTGGAAGAACATTGCAAAAGAGAATTTAAAAGAAATGATTTTAAGAGATA
GAAATCATCCTTGTATATTTATGTGGGGTGTGCGAATAAATGAGTCTTTAGATGACCACGATTTTTATAAAGAAATGAAT
GAAATAGCTCATAAATTAGACAGAAGTAGACCAACAGGTGGTGTTAGATATTTAAGAGATAGTGAAAAGCTAGAGGATGT
ATTTACATATAACGACTTTATATACAATTTAGAAGGCAAAATACAACTTCCAAATCACAAAAAGTATATGGTAACAGAAT
ATATGGGTCACATGTATCCGACAAAATCTTATGATAACCTTAATCGACTTATTACTCATGCAAGGTTGCATGCTCTTATT
CAAGACAAACAATATGGGATACCAAACATGGCTGGTGCATCAGGCTGGTGTGCATTTGATTATAATACCACAAGTGCTTT
TGGTTCAGGAGACAATATATGCTATCATGGAGTCTGTGATATATTTAGACTTCCAAAGTTTGCAGCTCATTTTTACAGGA
GTCAAGCCGACCCGCACTTATATGGACCCTATGTGTTTATAGCTTCGTACTTAATACCATCATTTGAGGAAGAGAACGGC
GATAAATTGCTTGTATTTAGCAATTGCGAAGAAGTAGAACTTTATATAAATGATAAATTTGTGAAAAGACAAATGCCCAA
TAGAGTTGATTTTCCTAGTTTACCACATCCGCCTTTTGAATTTTCAATGAAGGAATGCGGAATCAACTATATGGAGGTAA
GAGTTAATAACGCTTCTATTACTGCGATAGGTTTGATAGACGGTAAGGAAGTAGCAAGACATACATTAAGGCCATATGGG
AAACCACATAAATTAATTCTTTCTTGTGATGATAATGAGATTATGGCAGATGGCGCTGATTGTACACGGGTTGTTATAAG
TGTTGTAGATGAAAACGGCTCTATTCTTCCATATGCTAATATACCTGTATCATTTGAAATAGAAGGTGAAGGAAAACTGA
TTGGAGAAAATCCGTTGACATTAGAGGCTGGCAGAGGAGCAGTTTATGTAAAATCGACACGAAAGCCGGGAGAAATAATT
TTAAAAGCTAAATCTCATTATGTAGCGGAAGAAAGCAATGTATCTATAAAAACTAAGTCAATAGGATATTAA

Upstream 100 bases:

>100_bases
TATAGTGGTGATGAACTTATGTATGCAGGGAAAGTAATTCCAGAACTTAAAGGGGACTTTCAGAGCATTATGATGCATTT
TAAGGAGGAGAGTATTAAAG

Downstream 100 bases:

>100_bases
AAACCCACCCTTTGGGGTGGGTTTTATTATAGTATGTATAATTTCCTATTGGTAGCTAATCAATAATTTTTGAAAAAATA
AATTCCTACAAACTAAAAAT

Product: beta-galactosidase

Products: NA

Alternate protein names: Beta-gal; Lactase [H]

Number of amino acids: Translated: 743; Mature: 742

Protein sequence:

>743_residues
MGREILNFNVDWLYIPEDLNDAYKLDFDESNFEFVSLPHANKIFPHHYFKEEDYRFVSWYRKHFKLDSKYEGKKVYIHFE
GVMTVAMVYVNGEFVGEHKGGYTPFEFDITEYVKYGDFENLIAVQVDSREHKDIPPEGHLVDYMLFGGIYRNVWLKILNE
TYIQDVYFVVDKLQDSVAEISITTTIEGKEVRNAKILTEVINKEGAVCSSSVTDVKDMQKEIVQRIKMENPLTWYPDHPY
LYNVSVKLIAENEILDNYTFRTGIRTVHFGDDGKFYINGEPLKLRGLNRHQTFPYVGGAMPDRVQRKDADILKYDLGLNY
VRTSHYPQAVSFLDRCDEIGLLVFEEIPGWQHIGDENWKNIAKENLKEMILRDRNHPCIFMWGVRINESLDDHDFYKEMN
EIAHKLDRSRPTGGVRYLRDSEKLEDVFTYNDFIYNLEGKIQLPNHKKYMVTEYMGHMYPTKSYDNLNRLITHARLHALI
QDKQYGIPNMAGASGWCAFDYNTTSAFGSGDNICYHGVCDIFRLPKFAAHFYRSQADPHLYGPYVFIASYLIPSFEEENG
DKLLVFSNCEEVELYINDKFVKRQMPNRVDFPSLPHPPFEFSMKECGINYMEVRVNNASITAIGLIDGKEVARHTLRPYG
KPHKLILSCDDNEIMADGADCTRVVISVVDENGSILPYANIPVSFEIEGEGKLIGENPLTLEAGRGAVYVKSTRKPGEII
LKAKSHYVAEESNVSIKTKSIGY

Sequences:

>Translated_743_residues
MGREILNFNVDWLYIPEDLNDAYKLDFDESNFEFVSLPHANKIFPHHYFKEEDYRFVSWYRKHFKLDSKYEGKKVYIHFE
GVMTVAMVYVNGEFVGEHKGGYTPFEFDITEYVKYGDFENLIAVQVDSREHKDIPPEGHLVDYMLFGGIYRNVWLKILNE
TYIQDVYFVVDKLQDSVAEISITTTIEGKEVRNAKILTEVINKEGAVCSSSVTDVKDMQKEIVQRIKMENPLTWYPDHPY
LYNVSVKLIAENEILDNYTFRTGIRTVHFGDDGKFYINGEPLKLRGLNRHQTFPYVGGAMPDRVQRKDADILKYDLGLNY
VRTSHYPQAVSFLDRCDEIGLLVFEEIPGWQHIGDENWKNIAKENLKEMILRDRNHPCIFMWGVRINESLDDHDFYKEMN
EIAHKLDRSRPTGGVRYLRDSEKLEDVFTYNDFIYNLEGKIQLPNHKKYMVTEYMGHMYPTKSYDNLNRLITHARLHALI
QDKQYGIPNMAGASGWCAFDYNTTSAFGSGDNICYHGVCDIFRLPKFAAHFYRSQADPHLYGPYVFIASYLIPSFEEENG
DKLLVFSNCEEVELYINDKFVKRQMPNRVDFPSLPHPPFEFSMKECGINYMEVRVNNASITAIGLIDGKEVARHTLRPYG
KPHKLILSCDDNEIMADGADCTRVVISVVDENGSILPYANIPVSFEIEGEGKLIGENPLTLEAGRGAVYVKSTRKPGEII
LKAKSHYVAEESNVSIKTKSIGY
>Mature_742_residues
GREILNFNVDWLYIPEDLNDAYKLDFDESNFEFVSLPHANKIFPHHYFKEEDYRFVSWYRKHFKLDSKYEGKKVYIHFEG
VMTVAMVYVNGEFVGEHKGGYTPFEFDITEYVKYGDFENLIAVQVDSREHKDIPPEGHLVDYMLFGGIYRNVWLKILNET
YIQDVYFVVDKLQDSVAEISITTTIEGKEVRNAKILTEVINKEGAVCSSSVTDVKDMQKEIVQRIKMENPLTWYPDHPYL
YNVSVKLIAENEILDNYTFRTGIRTVHFGDDGKFYINGEPLKLRGLNRHQTFPYVGGAMPDRVQRKDADILKYDLGLNYV
RTSHYPQAVSFLDRCDEIGLLVFEEIPGWQHIGDENWKNIAKENLKEMILRDRNHPCIFMWGVRINESLDDHDFYKEMNE
IAHKLDRSRPTGGVRYLRDSEKLEDVFTYNDFIYNLEGKIQLPNHKKYMVTEYMGHMYPTKSYDNLNRLITHARLHALIQ
DKQYGIPNMAGASGWCAFDYNTTSAFGSGDNICYHGVCDIFRLPKFAAHFYRSQADPHLYGPYVFIASYLIPSFEEENGD
KLLVFSNCEEVELYINDKFVKRQMPNRVDFPSLPHPPFEFSMKECGINYMEVRVNNASITAIGLIDGKEVARHTLRPYGK
PHKLILSCDDNEIMADGADCTRVVISVVDENGSILPYANIPVSFEIEGEGKLIGENPLTLEAGRGAVYVKSTRKPGEIIL
KAKSHYVAEESNVSIKTKSIGY

Specific function: Unknown

COG id: COG3250

COG function: function code G; Beta-galactosidase/beta-glucuronidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 2 family [H]

Homologues:

Organism=Homo sapiens, GI268834192, Length=439, Percent_Identity=27.3348519362187, Blast_Score=136, Evalue=7e-32,
Organism=Escherichia coli, GI1787903, Length=472, Percent_Identity=26.271186440678, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI48994920, Length=423, Percent_Identity=29.3144208037825, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1786539, Length=379, Percent_Identity=27.7044854881267, Blast_Score=106, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17510825, Length=549, Percent_Identity=25.5009107468124, Blast_Score=137, Evalue=3e-32,
Organism=Drosophila melanogaster, GI19922582, Length=536, Percent_Identity=26.3059701492537, Blast_Score=166, Evalue=7e-41,
Organism=Drosophila melanogaster, GI62471735, Length=536, Percent_Identity=26.3059701492537, Blast_Score=166, Evalue=7e-41,
Organism=Drosophila melanogaster, GI24655438, Length=536, Percent_Identity=26.3059701492537, Blast_Score=166, Evalue=8e-41,
Organism=Drosophila melanogaster, GI24651745, Length=354, Percent_Identity=25.4237288135593, Blast_Score=126, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003344
- InterPro:   IPR008979
- InterPro:   IPR006101
- InterPro:   IPR013812
- InterPro:   IPR006104
- InterPro:   IPR006102
- InterPro:   IPR006103
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00703 Glyco_hydro_2; PF02836 Glyco_hydro_2_C; PF02837 Glyco_hydro_2_N [H]

EC number: =3.2.1.23 [H]

Molecular weight: Translated: 85877; Mature: 85746

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS00719 GLYCOSYL_HYDROL_F2_1 ; PS00608 GLYCOSYL_HYDROL_F2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGREILNFNVDWLYIPEDLNDAYKLDFDESNFEFVSLPHANKIFPHHYFKEEDYRFVSWY
CCCEEEEECEEEEECCCCCCCCEEECCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHH
RKHFKLDSKYEGKKVYIHFEGVMTVAMVYVNGEFVGEHKGGYTPFEFDITEYVKYGDFEN
HHHCCCCCCCCCCEEEEEECCEEEEEEEEECCEEEECCCCCCCCEEECHHHHHHCCCCCC
LIAVQVDSREHKDIPPEGHLVDYMLFGGIYRNVWLKILNETYIQDVYFVVDKLQDSVAEI
EEEEEECCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEE
SITTTIEGKEVRNAKILTEVINKEGAVCSSSVTDVKDMQKEIVQRIKMENPLTWYPDHPY
EEEEEECCCHHCCHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHCCCCCEECCCCCE
LYNVSVKLIAENEILDNYTFRTGIRTVHFGDDGKFYINGEPLKLRGLNRHQTFPYVGGAM
EEEEEEEEEECCCHHCCCEEECCCEEEEECCCCEEEECCCCEEEECCCCCCCCCCCCCCC
PDRVQRKDADILKYDLGLNYVRTSHYPQAVSFLDRCDEIGLLVFEEIPGWQHIGDENWKN
CHHHHHCCCCEEEEECCCCEEECCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHH
IAKENLKEMILRDRNHPCIFMWGVRINESLDDHDFYKEMNEIAHKLDRSRPTGGVRYLRD
HHHHHHHHHHHHCCCCCEEEEECCEECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECC
SEKLEDVFTYNDFIYNLEGKIQLPNHKKYMVTEYMGHMYPTKSYDNLNRLITHARLHALI
CHHHHHHHEECCEEEEECCEEECCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
QDKQYGIPNMAGASGWCAFDYNTTSAFGSGDNICYHGVCDIFRLPKFAAHFYRSQADPHL
HHCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCC
YGPYVFIASYLIPSFEEENGDKLLVFSNCEEVELYINDKFVKRQMPNRVDFPSLPHPPFE
CCHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEEEECCHHHHHHCCCCCCCCCCCCCCCC
FSMKECGINYMEVRVNNASITAIGLIDGKEVARHTLRPYGKPHKLILSCDDNEIMADGAD
CCHHHCCCEEEEEEECCCEEEEEEEECCHHHHHHHHCCCCCCCEEEEEECCCCEEECCCH
CTRVVISVVDENGSILPYANIPVSFEIEGEGKLIGENPLTLEAGRGAVYVKSTRKPGEII
HHEEEEEEECCCCCEEEEECCCEEEEECCCCEEECCCCEEEECCCCEEEEECCCCCCEEE
LKAKSHYVAEESNVSIKTKSIGY
EEECCCEEECCCCCEEEEECCCC
>Mature Secondary Structure 
GREILNFNVDWLYIPEDLNDAYKLDFDESNFEFVSLPHANKIFPHHYFKEEDYRFVSWY
CCEEEEECEEEEECCCCCCCCEEECCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHH
RKHFKLDSKYEGKKVYIHFEGVMTVAMVYVNGEFVGEHKGGYTPFEFDITEYVKYGDFEN
HHHCCCCCCCCCCEEEEEECCEEEEEEEEECCEEEECCCCCCCCEEECHHHHHHCCCCCC
LIAVQVDSREHKDIPPEGHLVDYMLFGGIYRNVWLKILNETYIQDVYFVVDKLQDSVAEI
EEEEEECCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEE
SITTTIEGKEVRNAKILTEVINKEGAVCSSSVTDVKDMQKEIVQRIKMENPLTWYPDHPY
EEEEEECCCHHCCHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHCCCCCEECCCCCE
LYNVSVKLIAENEILDNYTFRTGIRTVHFGDDGKFYINGEPLKLRGLNRHQTFPYVGGAM
EEEEEEEEEECCCHHCCCEEECCCEEEEECCCCEEEECCCCEEEECCCCCCCCCCCCCCC
PDRVQRKDADILKYDLGLNYVRTSHYPQAVSFLDRCDEIGLLVFEEIPGWQHIGDENWKN
CHHHHHCCCCEEEEECCCCEEECCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHH
IAKENLKEMILRDRNHPCIFMWGVRINESLDDHDFYKEMNEIAHKLDRSRPTGGVRYLRD
HHHHHHHHHHHHCCCCCEEEEECCEECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECC
SEKLEDVFTYNDFIYNLEGKIQLPNHKKYMVTEYMGHMYPTKSYDNLNRLITHARLHALI
CHHHHHHHEECCEEEEECCEEECCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
QDKQYGIPNMAGASGWCAFDYNTTSAFGSGDNICYHGVCDIFRLPKFAAHFYRSQADPHL
HHCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCC
YGPYVFIASYLIPSFEEENGDKLLVFSNCEEVELYINDKFVKRQMPNRVDFPSLPHPPFE
CCHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEEEECCHHHHHHCCCCCCCCCCCCCCCC
FSMKECGINYMEVRVNNASITAIGLIDGKEVARHTLRPYGKPHKLILSCDDNEIMADGAD
CCHHHCCCEEEEEEECCCEEEEEEEECCHHHHHHHHCCCCCCCEEEEEECCCCEEECCCH
CTRVVISVVDENGSILPYANIPVSFEIEGEGKLIGENPLTLEAGRGAVYVKSTRKPGEII
HHEEEEEEECCCCCEEEEECCCEEEEECCCCEEECCCCEEEECCCCEEEEECCCCCCEEE
LKAKSHYVAEESNVSIKTKSIGY
EEECCCEEECCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA