Definition Thermoanaerobacter sp. X514 chromosome, complete genome.
Accession NC_010320
Length 2,457,259

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The map label for this gene is ftsH2

Identifier: 167039684

GI number: 167039684

Start: 1067097

End: 1068629

Strand: Reverse

Name: ftsH2

Synonym: Teth514_1034

Alternate gene names: 167039684

Gene position: 1068629-1067097 (Counterclockwise)

Preceding gene: 167039692

Following gene: 167039662

Centisome position: 43.49

GC content: 33.33

Gene sequence:

>1533_bases
ATGAAAAAGAATTTGCATATTATTATTTTGGCGCTTTCTATCTTTATAAATTTACTTTTTATTTACATTTTTATCTCAGA
AGTAAAACCAAATCTAAATCTCAACCTTTCTTTTATCTTGACAGCAGCAGTAATTGTTGTAACCTACCTACTATTTAAAA
ATAAATTTTCGGAGCTCATGCCTGTAAACTACAACAATATCACTGAGACAAAGGAAGATACCAGTCATCGAAAAACCAAT
ATCACTTTTAAGGATGTGGCAGGATTAGATGAAGTAATCGATGAATTAAAAGTTATAATCGACTTTATGACAAATACAGA
AAAGTACAACAAAATGGGTGCAAAAATTCCTAAGGGTATATTATTTTACGGACCACCAGGCACAGGAAAAACTCTTTTGG
CTACGGCATTAGCTGGTGAAACCAATTCTACTTTTATCAGTGCTTCCGGTTCAGAATTTGTAGAGAAATATGTAGGAGTA
GGTGCAAGTCGCATAAGAGCTCTTTTCGCAAAAGCAAAAAAAAGCGCTCCCAGTATTATATTTATAGATGAGATAGATGC
TGTGGGAACAAAGAGAAACACCGATAACAATTCAGAAAAAGATCAAACTTTAAATCAACTGTTAGTAGAAATGGATGGTT
TTAATAGCAACGAAGGGATTATAGTCATAGGAGCAACTAATAGAATTGACATGTTAGACGAAGCCTTATTAAGGCCTGGA
AGATTTGATAGAACCATACACATTGGAGCACCTAATATGAAAGCAAGGTTGGAAATATTAAAGGTACATACTCGCAATAA
ACCCCTTGACGAAAGTGTATCTTTAAGTGAATTAGCTCGAAAAACTCACGGTATGACAGGGGCACATCTGGCTGCTATGT
GCAACGAAGCAGCAATACTGGCTGTAATGAAAAACAAAAGTAAAATTGGAAAGGAAGAGTTTGAAGAAGCATTAGAGCGC
GTAATCGCAGGTCTTAAAAAGAAAAATCCTTCTGTATTAGAAAAAGAACGAAATATTGCTGCATACCACGAAGCAGGTCA
CGCTCTTATTGGAAAAATTTTAAACGTAAATACTATAGAAAAAATTTCAATCGTTCCTCGAGGTGAAGCATTAGGATATG
TATTAAACTTTCCAAAAGAAGATGCCTTTTTACTAACAAAAACAGAGTTGAAAAATAAAATAACCATGCTTTTAGGGGGT
AGAGCTTCTGAGGAAATAATATTCAATGAAATTTCAACAGGAGCCGAAAATGACTTAAAAGAAGCTACAAAAATTGCCTA
TCAGATGGTTTGCAATTATGGAATGAGTGAATTGGGAAACAGGGTTTTTGACTTACACATGTTAAAATCCACAGAAATTG
TCGATAAAGAAATTGACAAAATTATAAATAGCTGTTATATACTTGCCAAAAAAATATTGCTGGAAAATAAACATAAAGTT
ATTGCAATAGCCGAAAAGCTTTTAGAAAAAGAATCAATTACAAAAGAAGAATTAGAAACATTATGGGAAGAAGAAAATAC
CTTATGCGTATGA

Upstream 100 bases:

>100_bases
TTTTTACCTTCAAAATCATTTTTTATACTCTTTCAATTAACGAATAAATTGCATTAATAAGCAAAAACTACATTCAGAAT
AAAAGTGGGGGCGAGAAATT

Downstream 100 bases:

>100_bases
CAAAAAAGCCTATTTAAAAACAGGCTTTTTTGTCATTTTCACTACTCCATATACTATAGCAAGTATAACTATAAAAGTAA
AGAAAGTATTTCTGAAAATT

Product: ATP-dependent metalloprotease FtsH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 510; Mature: 510

Protein sequence:

>510_residues
MKKNLHIIILALSIFINLLFIYIFISEVKPNLNLNLSFILTAAVIVVTYLLFKNKFSELMPVNYNNITETKEDTSHRKTN
ITFKDVAGLDEVIDELKVIIDFMTNTEKYNKMGAKIPKGILFYGPPGTGKTLLATALAGETNSTFISASGSEFVEKYVGV
GASRIRALFAKAKKSAPSIIFIDEIDAVGTKRNTDNNSEKDQTLNQLLVEMDGFNSNEGIIVIGATNRIDMLDEALLRPG
RFDRTIHIGAPNMKARLEILKVHTRNKPLDESVSLSELARKTHGMTGAHLAAMCNEAAILAVMKNKSKIGKEEFEEALER
VIAGLKKKNPSVLEKERNIAAYHEAGHALIGKILNVNTIEKISIVPRGEALGYVLNFPKEDAFLLTKTELKNKITMLLGG
RASEEIIFNEISTGAENDLKEATKIAYQMVCNYGMSELGNRVFDLHMLKSTEIVDKEIDKIINSCYILAKKILLENKHKV
IAIAEKLLEKESITKEELETLWEEENTLCV

Sequences:

>Translated_510_residues
MKKNLHIIILALSIFINLLFIYIFISEVKPNLNLNLSFILTAAVIVVTYLLFKNKFSELMPVNYNNITETKEDTSHRKTN
ITFKDVAGLDEVIDELKVIIDFMTNTEKYNKMGAKIPKGILFYGPPGTGKTLLATALAGETNSTFISASGSEFVEKYVGV
GASRIRALFAKAKKSAPSIIFIDEIDAVGTKRNTDNNSEKDQTLNQLLVEMDGFNSNEGIIVIGATNRIDMLDEALLRPG
RFDRTIHIGAPNMKARLEILKVHTRNKPLDESVSLSELARKTHGMTGAHLAAMCNEAAILAVMKNKSKIGKEEFEEALER
VIAGLKKKNPSVLEKERNIAAYHEAGHALIGKILNVNTIEKISIVPRGEALGYVLNFPKEDAFLLTKTELKNKITMLLGG
RASEEIIFNEISTGAENDLKEATKIAYQMVCNYGMSELGNRVFDLHMLKSTEIVDKEIDKIINSCYILAKKILLENKHKV
IAIAEKLLEKESITKEELETLWEEENTLCV
>Mature_510_residues
MKKNLHIIILALSIFINLLFIYIFISEVKPNLNLNLSFILTAAVIVVTYLLFKNKFSELMPVNYNNITETKEDTSHRKTN
ITFKDVAGLDEVIDELKVIIDFMTNTEKYNKMGAKIPKGILFYGPPGTGKTLLATALAGETNSTFISASGSEFVEKYVGV
GASRIRALFAKAKKSAPSIIFIDEIDAVGTKRNTDNNSEKDQTLNQLLVEMDGFNSNEGIIVIGATNRIDMLDEALLRPG
RFDRTIHIGAPNMKARLEILKVHTRNKPLDESVSLSELARKTHGMTGAHLAAMCNEAAILAVMKNKSKIGKEEFEEALER
VIAGLKKKNPSVLEKERNIAAYHEAGHALIGKILNVNTIEKISIVPRGEALGYVLNFPKEDAFLLTKTELKNKITMLLGG
RASEEIIFNEISTGAENDLKEATKIAYQMVCNYGMSELGNRVFDLHMLKSTEIVDKEIDKIINSCYILAKKILLENKHKV
IAIAEKLLEKESITKEELETLWEEENTLCV

Specific function: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins

COG id: COG0465

COG function: function code O; ATP-dependent Zn proteases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein; Cytoplasmic side

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase M41 family

Homologues:

Organism=Homo sapiens, GI300192933, Length=453, Percent_Identity=46.3576158940397, Blast_Score=397, Evalue=1e-110,
Organism=Homo sapiens, GI4507173, Length=446, Percent_Identity=41.9282511210762, Blast_Score=353, Evalue=2e-97,
Organism=Homo sapiens, GI7657689, Length=476, Percent_Identity=41.1764705882353, Blast_Score=338, Evalue=6e-93,
Organism=Homo sapiens, GI21327685, Length=476, Percent_Identity=41.1764705882353, Blast_Score=338, Evalue=6e-93,
Organism=Homo sapiens, GI24497435, Length=255, Percent_Identity=44.7058823529412, Blast_Score=226, Evalue=3e-59,
Organism=Homo sapiens, GI24430151, Length=256, Percent_Identity=42.96875, Blast_Score=220, Evalue=3e-57,
Organism=Homo sapiens, GI21361144, Length=285, Percent_Identity=41.7543859649123, Blast_Score=218, Evalue=8e-57,
Organism=Homo sapiens, GI89064750, Length=253, Percent_Identity=41.501976284585, Blast_Score=202, Evalue=4e-52,
Organism=Homo sapiens, GI5729991, Length=253, Percent_Identity=41.501976284585, Blast_Score=202, Evalue=4e-52,
Organism=Homo sapiens, GI195539395, Length=300, Percent_Identity=38.3333333333333, Blast_Score=202, Evalue=5e-52,
Organism=Homo sapiens, GI24430155, Length=253, Percent_Identity=41.501976284585, Blast_Score=202, Evalue=7e-52,
Organism=Homo sapiens, GI6005942, Length=244, Percent_Identity=40.9836065573771, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI4506209, Length=254, Percent_Identity=38.9763779527559, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI45643123, Length=273, Percent_Identity=37.7289377289377, Blast_Score=192, Evalue=5e-49,
Organism=Homo sapiens, GI45643125, Length=273, Percent_Identity=37.7289377289377, Blast_Score=192, Evalue=6e-49,
Organism=Homo sapiens, GI157671927, Length=292, Percent_Identity=35.6164383561644, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI4505725, Length=273, Percent_Identity=35.1648351648352, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI24497618, Length=311, Percent_Identity=36.6559485530547, Blast_Score=182, Evalue=7e-46,
Organism=Homo sapiens, GI153792536, Length=237, Percent_Identity=40.5063291139241, Blast_Score=176, Evalue=5e-44,
Organism=Homo sapiens, GI229577436, Length=274, Percent_Identity=35.4014598540146, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI194018488, Length=267, Percent_Identity=38.9513108614232, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI31377644, Length=270, Percent_Identity=36.2962962962963, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI40806173, Length=138, Percent_Identity=52.1739130434783, Blast_Score=155, Evalue=7e-38,
Organism=Homo sapiens, GI7019569, Length=264, Percent_Identity=35.9848484848485, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI14149767, Length=253, Percent_Identity=35.1778656126482, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI62177112, Length=253, Percent_Identity=35.1778656126482, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI40806170, Length=226, Percent_Identity=38.4955752212389, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI11875211, Length=226, Percent_Identity=38.4955752212389, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI17865802, Length=239, Percent_Identity=38.4937238493724, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI156564401, Length=237, Percent_Identity=37.9746835443038, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI5901990, Length=242, Percent_Identity=34.297520661157, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI310125280, Length=237, Percent_Identity=37.9746835443038, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI310125282, Length=237, Percent_Identity=37.9746835443038, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI31742536, Length=227, Percent_Identity=33.920704845815, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI112789543, Length=227, Percent_Identity=33.920704845815, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI226371754, Length=240, Percent_Identity=35.4166666666667, Blast_Score=126, Evalue=5e-29,
Organism=Homo sapiens, GI64084766, Length=276, Percent_Identity=27.1739130434783, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI116292174, Length=250, Percent_Identity=26.8, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI4757852, Length=194, Percent_Identity=30.4123711340206, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI119964730, Length=194, Percent_Identity=30.4123711340206, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI75677353, Length=194, Percent_Identity=33.5051546391753, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI283436224, Length=194, Percent_Identity=30.9278350515464, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI283436222, Length=194, Percent_Identity=30.9278350515464, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI283436220, Length=194, Percent_Identity=30.9278350515464, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1789568, Length=457, Percent_Identity=44.2013129102845, Blast_Score=386, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI71994521, Length=438, Percent_Identity=44.5205479452055, Blast_Score=378, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI17554264, Length=429, Percent_Identity=41.025641025641, Blast_Score=330, Evalue=8e-91,
Organism=Caenorhabditis elegans, GI115534323, Length=447, Percent_Identity=41.834451901566, Blast_Score=329, Evalue=2e-90,
Organism=Caenorhabditis elegans, GI25144281, Length=255, Percent_Identity=44.7058823529412, Blast_Score=226, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI17554786, Length=255, Percent_Identity=44.3137254901961, Blast_Score=226, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI25144278, Length=255, Percent_Identity=44.7058823529412, Blast_Score=225, Evalue=4e-59,
Organism=Caenorhabditis elegans, GI17508701, Length=285, Percent_Identity=41.4035087719298, Blast_Score=218, Evalue=7e-57,
Organism=Caenorhabditis elegans, GI17505546, Length=253, Percent_Identity=44.2687747035573, Blast_Score=217, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI17563250, Length=256, Percent_Identity=43.359375, Blast_Score=216, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI17563248, Length=254, Percent_Identity=39.3700787401575, Blast_Score=200, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI71987364, Length=246, Percent_Identity=41.4634146341463, Blast_Score=198, Evalue=7e-51,
Organism=Caenorhabditis elegans, GI71987372, Length=246, Percent_Identity=41.4634146341463, Blast_Score=197, Evalue=9e-51,
Organism=Caenorhabditis elegans, GI17532375, Length=240, Percent_Identity=40, Blast_Score=195, Evalue=6e-50,
Organism=Caenorhabditis elegans, GI17508053, Length=249, Percent_Identity=40.1606425702811, Blast_Score=194, Evalue=7e-50,
Organism=Caenorhabditis elegans, GI17531535, Length=242, Percent_Identity=39.2561983471074, Blast_Score=191, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17554784, Length=249, Percent_Identity=39.7590361445783, Blast_Score=184, Evalue=9e-47,
Organism=Caenorhabditis elegans, GI17537217, Length=272, Percent_Identity=38.2352941176471, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI133931034, Length=275, Percent_Identity=36.3636363636364, Blast_Score=174, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI193206116, Length=275, Percent_Identity=36.3636363636364, Blast_Score=174, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI193206114, Length=275, Percent_Identity=36.3636363636364, Blast_Score=174, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI25153574, Length=235, Percent_Identity=40.4255319148936, Blast_Score=173, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI193209502, Length=234, Percent_Identity=40.1709401709402, Blast_Score=168, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI17562804, Length=244, Percent_Identity=35.2459016393443, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI133901662, Length=228, Percent_Identity=37.719298245614, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI133901658, Length=228, Percent_Identity=37.719298245614, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17541224, Length=225, Percent_Identity=36, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17541226, Length=225, Percent_Identity=36, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI25146157, Length=248, Percent_Identity=36.6935483870968, Blast_Score=134, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17570397, Length=156, Percent_Identity=46.1538461538462, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI32566590, Length=156, Percent_Identity=46.1538461538462, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI86561515, Length=285, Percent_Identity=31.9298245614035, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17560432, Length=226, Percent_Identity=35.8407079646018, Blast_Score=127, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI32563584, Length=194, Percent_Identity=38.659793814433, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17508421, Length=203, Percent_Identity=37.4384236453202, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI71990294, Length=197, Percent_Identity=31.9796954314721, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71990340, Length=166, Percent_Identity=30.1204819277108, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71990335, Length=166, Percent_Identity=30.1204819277108, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6320854, Length=442, Percent_Identity=45.9276018099548, Blast_Score=375, Evalue=1e-104,
Organism=Saccharomyces cerevisiae, GI6323736, Length=436, Percent_Identity=45.6422018348624, Blast_Score=367, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6325281, Length=436, Percent_Identity=41.9724770642202, Blast_Score=351, Evalue=2e-97,
Organism=Saccharomyces cerevisiae, GI6324691, Length=250, Percent_Identity=44.4, Blast_Score=220, Evalue=4e-58,
Organism=Saccharomyces cerevisiae, GI6321390, Length=245, Percent_Identity=42.8571428571429, Blast_Score=214, Evalue=2e-56,
Organism=Saccharomyces cerevisiae, GI6320197, Length=245, Percent_Identity=43.265306122449, Blast_Score=210, Evalue=4e-55,
Organism=Saccharomyces cerevisiae, GI6320077, Length=227, Percent_Identity=43.6123348017621, Blast_Score=205, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6322704, Length=258, Percent_Identity=39.1472868217054, Blast_Score=203, Evalue=6e-53,
Organism=Saccharomyces cerevisiae, GI6323429, Length=249, Percent_Identity=41.3654618473896, Blast_Score=197, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6324833, Length=258, Percent_Identity=41.4728682170543, Blast_Score=192, Evalue=9e-50,
Organism=Saccharomyces cerevisiae, GI6322994, Length=230, Percent_Identity=42.1739130434783, Blast_Score=192, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6320602, Length=247, Percent_Identity=41.2955465587045, Blast_Score=189, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6321709, Length=238, Percent_Identity=41.1764705882353, Blast_Score=186, Evalue=8e-48,
Organism=Saccharomyces cerevisiae, GI6324000, Length=230, Percent_Identity=42.6086956521739, Blast_Score=182, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6322651, Length=281, Percent_Identity=35.5871886120996, Blast_Score=169, Evalue=6e-43,
Organism=Saccharomyces cerevisiae, GI6321465, Length=225, Percent_Identity=37.7777777777778, Blast_Score=145, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6325431, Length=232, Percent_Identity=36.6379310344828, Blast_Score=143, Evalue=7e-35,
Organism=Saccharomyces cerevisiae, GI6319554, Length=242, Percent_Identity=36.7768595041322, Blast_Score=137, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6325183, Length=235, Percent_Identity=34.8936170212766, Blast_Score=129, Evalue=8e-31,
Organism=Saccharomyces cerevisiae, GI6320887, Length=243, Percent_Identity=32.9218106995885, Blast_Score=119, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6320583, Length=165, Percent_Identity=33.9393939393939, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28574878, Length=452, Percent_Identity=45.7964601769911, Blast_Score=399, Evalue=1e-111,
Organism=Drosophila melanogaster, GI24665814, Length=452, Percent_Identity=45.7964601769911, Blast_Score=398, Evalue=1e-111,
Organism=Drosophila melanogaster, GI24658770, Length=500, Percent_Identity=40, Blast_Score=351, Evalue=8e-97,
Organism=Drosophila melanogaster, GI24639391, Length=451, Percent_Identity=41.4634146341463, Blast_Score=347, Evalue=1e-95,
Organism=Drosophila melanogaster, GI24651451, Length=254, Percent_Identity=44.8818897637795, Blast_Score=228, Evalue=7e-60,
Organism=Drosophila melanogaster, GI19920408, Length=255, Percent_Identity=44.7058823529412, Blast_Score=227, Evalue=2e-59,
Organism=Drosophila melanogaster, GI24649446, Length=256, Percent_Identity=44.921875, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI17738151, Length=285, Percent_Identity=42.1052631578947, Blast_Score=219, Evalue=2e-57,
Organism=Drosophila melanogaster, GI17137738, Length=254, Percent_Identity=39.3700787401575, Blast_Score=199, Evalue=4e-51,
Organism=Drosophila melanogaster, GI18860063, Length=244, Percent_Identity=40.9836065573771, Blast_Score=196, Evalue=2e-50,
Organism=Drosophila melanogaster, GI19921202, Length=250, Percent_Identity=38.4, Blast_Score=196, Evalue=4e-50,
Organism=Drosophila melanogaster, GI161076488, Length=229, Percent_Identity=40.174672489083, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI17137560, Length=229, Percent_Identity=40.174672489083, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI281361487, Length=244, Percent_Identity=40.5737704918033, Blast_Score=194, Evalue=2e-49,
Organism=Drosophila melanogaster, GI161076486, Length=229, Percent_Identity=40.174672489083, Blast_Score=193, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24640100, Length=283, Percent_Identity=38.5159010600707, Blast_Score=192, Evalue=4e-49,
Organism=Drosophila melanogaster, GI24656820, Length=301, Percent_Identity=35.5481727574751, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI24663015, Length=285, Percent_Identity=37.8947368421053, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI24656825, Length=301, Percent_Identity=35.5481727574751, Blast_Score=189, Evalue=4e-48,
Organism=Drosophila melanogaster, GI24660075, Length=275, Percent_Identity=37.4545454545455, Blast_Score=189, Evalue=5e-48,
Organism=Drosophila melanogaster, GI281365776, Length=275, Percent_Identity=37.4545454545455, Blast_Score=189, Evalue=5e-48,
Organism=Drosophila melanogaster, GI45552965, Length=275, Percent_Identity=37.4545454545455, Blast_Score=188, Evalue=8e-48,
Organism=Drosophila melanogaster, GI45554047, Length=166, Percent_Identity=49.3975903614458, Blast_Score=178, Evalue=6e-45,
Organism=Drosophila melanogaster, GI24652279, Length=190, Percent_Identity=42.6315789473684, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI21355121, Length=265, Percent_Identity=33.2075471698113, Blast_Score=163, Evalue=3e-40,
Organism=Drosophila melanogaster, GI281363136, Length=267, Percent_Identity=33.7078651685393, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI78707192, Length=267, Percent_Identity=33.7078651685393, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI18859657, Length=236, Percent_Identity=40.6779661016949, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI20129529, Length=253, Percent_Identity=35.5731225296443, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI20129423, Length=226, Percent_Identity=36.283185840708, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI17864540, Length=230, Percent_Identity=37.3913043478261, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI281360144, Length=263, Percent_Identity=34.9809885931559, Blast_Score=136, Evalue=4e-32,
Organism=Drosophila melanogaster, GI281360140, Length=263, Percent_Identity=34.9809885931559, Blast_Score=136, Evalue=4e-32,
Organism=Drosophila melanogaster, GI28573010, Length=234, Percent_Identity=39.3162393162393, Blast_Score=136, Evalue=4e-32,
Organism=Drosophila melanogaster, GI281360136, Length=263, Percent_Identity=34.9809885931559, Blast_Score=136, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24644411, Length=263, Percent_Identity=34.9809885931559, Blast_Score=136, Evalue=4e-32,
Organism=Drosophila melanogaster, GI281360142, Length=263, Percent_Identity=34.9809885931559, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI21357333, Length=263, Percent_Identity=34.9809885931559, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI281360146, Length=263, Percent_Identity=34.9809885931559, Blast_Score=135, Evalue=5e-32,
Organism=Drosophila melanogaster, GI281360138, Length=263, Percent_Identity=34.9809885931559, Blast_Score=135, Evalue=5e-32,
Organism=Drosophila melanogaster, GI24581396, Length=232, Percent_Identity=35.3448275862069, Blast_Score=135, Evalue=6e-32,
Organism=Drosophila melanogaster, GI28571849, Length=225, Percent_Identity=36.8888888888889, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28571847, Length=225, Percent_Identity=36.8888888888889, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24644145, Length=253, Percent_Identity=33.596837944664, Blast_Score=133, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24639486, Length=284, Percent_Identity=32.3943661971831, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI20129417, Length=155, Percent_Identity=37.4193548387097, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24583262, Length=155, Percent_Identity=37.4193548387097, Blast_Score=80, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FTSH2_THEPX (B0K657)

Other databases:

- EMBL:   CP000923
- RefSeq:   YP_001662669.1
- ProteinModelPortal:   B0K657
- GeneID:   5876050
- GenomeReviews:   CP000923_GR
- KEGG:   tex:Teth514_1034
- HOGENOM:   HBG724153
- OMA:   CARDESK
- ProtClustDB:   CLSK901513
- BioCyc:   TSP1755:TETH514_1034-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01458
- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR003960
- InterPro:   IPR005936
- InterPro:   IPR000642
- SMART:   SM00382
- TIGRFAMs:   TIGR01241

Pfam domain/function: PF00004 AAA; PF01434 Peptidase_M41

EC number: 3.4.24.- [C]

Molecular weight: Translated: 56836; Mature: 56836

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: PS00674 AAA

Important sites: ACT_SITE 344-344

Signals:

None

Transmembrane regions:

HASH(0x179847f0)-; HASH(0x193688b0)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MKKNLHIIILALSIFINLLFIYIFISEVKPNLNLNLSFILTAAVIVVTYLLFKNKFSELM
CCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
PVNYNNITETKEDTSHRKTNITFKDVAGLDEVIDELKVIIDFMTNTEKYNKMGAKIPKGI
CCCCCCCCCCCHHCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCE
LFYGPPGTGKTLLATALAGETNSTFISASGSEFVEKYVGVGASRIRALFAKAKKSAPSII
EEECCCCCCHHHHHHHHCCCCCCEEEECCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCEE
FIDEIDAVGTKRNTDNNSEKDQTLNQLLVEMDGFNSNEGIIVIGATNRIDMLDEALLRPG
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHCCC
RFDRTIHIGAPNMKARLEILKVHTRNKPLDESVSLSELARKTHGMTGAHLAAMCNEAAIL
CCCCEEEECCCCHHHHHHEEEEECCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHCCHHEE
AVMKNKSKIGKEEFEEALERVIAGLKKKNPSVLEKERNIAAYHEAGHALIGKILNVNTIE
EEECCCHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCEE
KISIVPRGEALGYVLNFPKEDAFLLTKTELKNKITMLLGGRASEEIIFNEISTGAENDLK
EEEEEECCCCCCCEEECCCCCCEEEEHHHHHCCEEEEECCCCCHHHHHHHHCCCCCHHHH
EATKIAYQMVCNYGMSELGNRVFDLHMLKSTEIVDKEIDKIINSCYILAKKILLENKHKV
HHHHHHHHHHHHCCHHHHCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
IAIAEKLLEKESITKEELETLWEEENTLCV
HHHHHHHHHHHCCCHHHHHHHHCCCCCCCH
>Mature Secondary Structure
MKKNLHIIILALSIFINLLFIYIFISEVKPNLNLNLSFILTAAVIVVTYLLFKNKFSELM
CCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
PVNYNNITETKEDTSHRKTNITFKDVAGLDEVIDELKVIIDFMTNTEKYNKMGAKIPKGI
CCCCCCCCCCCHHCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCE
LFYGPPGTGKTLLATALAGETNSTFISASGSEFVEKYVGVGASRIRALFAKAKKSAPSII
EEECCCCCCHHHHHHHHCCCCCCEEEECCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCEE
FIDEIDAVGTKRNTDNNSEKDQTLNQLLVEMDGFNSNEGIIVIGATNRIDMLDEALLRPG
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHCCC
RFDRTIHIGAPNMKARLEILKVHTRNKPLDESVSLSELARKTHGMTGAHLAAMCNEAAIL
CCCCEEEECCCCHHHHHHEEEEECCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHCCHHEE
AVMKNKSKIGKEEFEEALERVIAGLKKKNPSVLEKERNIAAYHEAGHALIGKILNVNTIE
EEECCCHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCEE
KISIVPRGEALGYVLNFPKEDAFLLTKTELKNKITMLLGGRASEEIIFNEISTGAENDLK
EEEEEECCCCCCCEEECCCCCCEEEEHHHHHCCEEEEECCCCCHHHHHHHHCCCCCHHHH
EATKIAYQMVCNYGMSELGNRVFDLHMLKSTEIVDKEIDKIINSCYILAKKILLENKHKV
HHHHHHHHHHHHCCHHHHCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
IAIAEKLLEKESITKEELETLWEEENTLCV
HHHHHHHHHHHCCCHHHHHHHHCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA