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The map label for this gene is 167039678

Identifier: 167039678

GI number: 167039678

Start: 1058911

End: 1060761

Strand: Direct

Name: 167039678

Synonym: Teth514_1028

Alternate gene names: NA

Gene position: 1058911-1060761 (Clockwise)

Preceding gene: 167039677

Following gene: 167039679

Centisome position: 43.09

GC content: 27.71

Gene sequence:

>1851_bases
TTGGTAAAGAAATTGGACAAAAAATTATATGAATATTTGCTGTTGTGGCAGATAATACTTGAAATTTATATAGGTATTCC
TGAAGAGGCAAAAGAGCATTTTTTTGAGCTAAAAAGCGAATTAGAAATTGATGAACATAATTTAGCTTTGTTTATAAAAA
GTGTGATTCTTTTAGATTTGGTAGAAGAATCTTTAAAAACAAAAAACCTTTTTGAAGCATTAATGAATTATAGTGGGGAA
GACCAATGGATAAAATTTTATTTATTGTTACTTTCTTTTAAAAATAAAAGAAGGATTTTAGAAGTTTTGGAAGAATTACT
TTATATGGAGAAAAAAGTAGAAGATAAATTGTTACTGCCTAAAATATATGGGCTTATAGCTGAAATATACGAAGAAATTG
GTGAAATAAAAGGGCACCAATTCTTAGATAAAGCTTATAAATTAAATCCTCAAGATTTATATATATTGCGGCTAAAATTA
AAATATGGCCTTATTAGTGAAGAAGAAAAACAAAATCTTAAACTTTATCGTTTGTTTCCAGAAGATTCGAAATTAATAAA
TGAGTATTACCATAAAACCAGAAAAAATTTTAACTCCATCCATAACTTTAAATTTTTTTGTTGGGGAGGGGATAATATTG
GTGCTAGCTCTTATTTGGTATCCTATGAGGGAATAAATATTTTACTAGATGCGGGAGCTTTGATTAAGGATAAAACCTTA
TATTACAATTCTATAAAAAATTTACCTATAGATATTAAAGATATTGATTTGGTAATTATTACTCATGTTCATTTAGACCA
TTCTGGGGGAATTGTAGAATTATTAAGAAAAGGTTTAAACTCTCCGATTATAATATCAAGACCTACTAAAGAAATTTTGA
AGCAAATATTTTTGCGGGGACATACAAAATTGGAGGTAAAAATAGAAGAAGAAATTATAAATTTTGACAGTCAGATTATA
AGTTTTGATACAGAAGAAGAAAGTAGTTTTAGAATAAAAAATAAAGAAGTAAAACTTAAGTTATTTCCTGCGGGGCATAT
TTTAGGGGCTGTAGCTGTGTATCTTGAGATTGACGGGATAAAAATTTTTTATACAGGTGATTTTACATTAAAAGATGTGG
AAAGCAATAAAGGACTTAGATTTCTTCCCGATTTAAAAGTAGATATTTTAATAACTGAAGCTACTTATGGTTACGGCAAT
AACTTTGGTGTCCAAAATAAGTATTTACAGGATAAATTGATACTTAAGTCGATAGAAAAACTATTAAAAGATGAAGAGAG
AATACTTTTACCTGTATATGCTATTGGTAAAGGGCAAGACCTATTATTATTTTTTAGAAAAACTTTTTCATATATTCCTT
TTAATGTGTATGTAGATGGAGATATAGCATATTTTAGTAAATTATATGAAAATTTTGCTGGGCCCATATATGGAAATGGA
ATACTAAATGTGGCTGGAAATACTTTATACACTGATAGAAAAGATTTTATAAAAAAGGAAATAGCCCTAGGCAATTGCGT
GATTCTCGCCAGTTCAAATGACTTAAAAGAGGGAAGTGCATCTTTTATATATGCTTTTGAAATAAAAAATTTTTCAAAGG
GCTGTATTATGAATCTCGATACTAATAATAGAGAAATTGAAGGTTTAAAAAATTATCAAATTGGAATGTTAAATCATGCA
AATATGGTAGACCTATTAGAAACAGTTATAAAGATGGCTCCATCTGCTGTTTTTGTAATTCACAGGGGATACGAAAGTAA
GAGTGAAATAAATATAGAAACAATTTTAAAAAGAATTGAAGGAATAAAAGTTTTTGCACCAAAAGAAGGAGAAATAATAG
AACTTCAATAG

Upstream 100 bases:

>100_bases
ATTTTTAAATATTTATGATGTATACGATAACAACCTAAAAGAATTTATAGAAAAGGAGGATTATATAAATGCTTATTGGT
ATGTTTTTCAGCAAAAAAGT

Downstream 100 bases:

>100_bases
GGGGGAGTTTATGAAAAGATATGTAGGAATAGATTTAGGTACTACGAATACGGTTGCATCAGTTTTGGAAATATCTCAAG
AAGGGGAATTACTGCCTCGG

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 616; Mature: 616

Protein sequence:

>616_residues
MVKKLDKKLYEYLLLWQIILEIYIGIPEEAKEHFFELKSELEIDEHNLALFIKSVILLDLVEESLKTKNLFEALMNYSGE
DQWIKFYLLLLSFKNKRRILEVLEELLYMEKKVEDKLLLPKIYGLIAEIYEEIGEIKGHQFLDKAYKLNPQDLYILRLKL
KYGLISEEEKQNLKLYRLFPEDSKLINEYYHKTRKNFNSIHNFKFFCWGGDNIGASSYLVSYEGINILLDAGALIKDKTL
YYNSIKNLPIDIKDIDLVIITHVHLDHSGGIVELLRKGLNSPIIISRPTKEILKQIFLRGHTKLEVKIEEEIINFDSQII
SFDTEEESSFRIKNKEVKLKLFPAGHILGAVAVYLEIDGIKIFYTGDFTLKDVESNKGLRFLPDLKVDILITEATYGYGN
NFGVQNKYLQDKLILKSIEKLLKDEERILLPVYAIGKGQDLLLFFRKTFSYIPFNVYVDGDIAYFSKLYENFAGPIYGNG
ILNVAGNTLYTDRKDFIKKEIALGNCVILASSNDLKEGSASFIYAFEIKNFSKGCIMNLDTNNREIEGLKNYQIGMLNHA
NMVDLLETVIKMAPSAVFVIHRGYESKSEINIETILKRIEGIKVFAPKEGEIIELQ

Sequences:

>Translated_616_residues
MVKKLDKKLYEYLLLWQIILEIYIGIPEEAKEHFFELKSELEIDEHNLALFIKSVILLDLVEESLKTKNLFEALMNYSGE
DQWIKFYLLLLSFKNKRRILEVLEELLYMEKKVEDKLLLPKIYGLIAEIYEEIGEIKGHQFLDKAYKLNPQDLYILRLKL
KYGLISEEEKQNLKLYRLFPEDSKLINEYYHKTRKNFNSIHNFKFFCWGGDNIGASSYLVSYEGINILLDAGALIKDKTL
YYNSIKNLPIDIKDIDLVIITHVHLDHSGGIVELLRKGLNSPIIISRPTKEILKQIFLRGHTKLEVKIEEEIINFDSQII
SFDTEEESSFRIKNKEVKLKLFPAGHILGAVAVYLEIDGIKIFYTGDFTLKDVESNKGLRFLPDLKVDILITEATYGYGN
NFGVQNKYLQDKLILKSIEKLLKDEERILLPVYAIGKGQDLLLFFRKTFSYIPFNVYVDGDIAYFSKLYENFAGPIYGNG
ILNVAGNTLYTDRKDFIKKEIALGNCVILASSNDLKEGSASFIYAFEIKNFSKGCIMNLDTNNREIEGLKNYQIGMLNHA
NMVDLLETVIKMAPSAVFVIHRGYESKSEINIETILKRIEGIKVFAPKEGEIIELQ
>Mature_616_residues
MVKKLDKKLYEYLLLWQIILEIYIGIPEEAKEHFFELKSELEIDEHNLALFIKSVILLDLVEESLKTKNLFEALMNYSGE
DQWIKFYLLLLSFKNKRRILEVLEELLYMEKKVEDKLLLPKIYGLIAEIYEEIGEIKGHQFLDKAYKLNPQDLYILRLKL
KYGLISEEEKQNLKLYRLFPEDSKLINEYYHKTRKNFNSIHNFKFFCWGGDNIGASSYLVSYEGINILLDAGALIKDKTL
YYNSIKNLPIDIKDIDLVIITHVHLDHSGGIVELLRKGLNSPIIISRPTKEILKQIFLRGHTKLEVKIEEEIINFDSQII
SFDTEEESSFRIKNKEVKLKLFPAGHILGAVAVYLEIDGIKIFYTGDFTLKDVESNKGLRFLPDLKVDILITEATYGYGN
NFGVQNKYLQDKLILKSIEKLLKDEERILLPVYAIGKGQDLLLFFRKTFSYIPFNVYVDGDIAYFSKLYENFAGPIYGNG
ILNVAGNTLYTDRKDFIKKEIALGNCVILASSNDLKEGSASFIYAFEIKNFSKGCIMNLDTNNREIEGLKNYQIGMLNHA
NMVDLLETVIKMAPSAVFVIHRGYESKSEINIETILKRIEGIKVFAPKEGEIIELQ

Specific function: Unknown

COG id: COG1236

COG function: function code J; Predicted exonuclease of the beta-lactamase fold involved in RNA processing

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family [H]

Homologues:

Organism=Homo sapiens, GI33300633, Length=455, Percent_Identity=23.956043956044, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI7706427, Length=258, Percent_Identity=29.4573643410853, Blast_Score=96, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI32566029, Length=361, Percent_Identity=26.0387811634349, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI32564696, Length=274, Percent_Identity=25.1824817518248, Blast_Score=99, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6323307, Length=264, Percent_Identity=27.6515151515151, Blast_Score=114, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24648013, Length=326, Percent_Identity=26.9938650306748, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI21358523, Length=253, Percent_Identity=27.2727272727273, Blast_Score=99, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022712
- InterPro:   IPR001279
- InterPro:   IPR011108 [H]

Pfam domain/function: PF10996 Beta-Casp; PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 71207; Mature: 71207

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKKLDKKLYEYLLLWQIILEIYIGIPEEAKEHFFELKSELEIDEHNLALFIKSVILLDL
CCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
VEESLKTKNLFEALMNYSGEDQWIKFYLLLLSFKNKRRILEVLEELLYMEKKVEDKLLLP
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHH
KIYGLIAEIYEEIGEIKGHQFLDKAYKLNPQDLYILRLKLKYGLISEEEKQNLKLYRLFP
HHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCCCEEEEECC
EDSKLINEYYHKTRKNFNSIHNFKFFCWGGDNIGASSYLVSYEGINILLDAGALIKDKTL
CHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEEEECCEEEEEECCCEEECCEE
YYNSIKNLPIDIKDIDLVIITHVHLDHSGGIVELLRKGLNSPIIISRPTKEILKQIFLRG
EECCCCCCCCEEECCCEEEEEEEEECCCCCHHHHHHHCCCCCEEEECCHHHHHHHHHHCC
HTKLEVKIEEEIINFDSQIISFDTEEESSFRIKNKEVKLKLFPAGHILGAVAVYLEIDGI
CCEEEEEEHHHHHCCCCCEEEECCCCCCCEEEECCEEEEEEECCHHHHEEEEEEEEECCE
KIFYTGDFTLKDVESNKGLRFLPDLKVDILITEATYGYGNNFGVQNKYLQDKLILKSIEK
EEEEECCEEEEECCCCCCEEECCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
LLKDEERILLPVYAIGKGQDLLLFFRKTFSYIPFNVYVDGDIAYFSKLYENFAGPIYGNG
HHCCCCEEEEEEEEECCCCHHHHEEHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCCCCC
ILNVAGNTLYTDRKDFIKKEIALGNCVILASSNDLKEGSASFIYAFEIKNFSKGCIMNLD
EEEECCCEEECCHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEEECCCCCCEEEEEC
TNNREIEGLKNYQIGMLNHANMVDLLETVIKMAPSAVFVIHRGYESKSEINIETILKRIE
CCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHC
GIKVFAPKEGEIIELQ
CCEEECCCCCCEEEEC
>Mature Secondary Structure
MVKKLDKKLYEYLLLWQIILEIYIGIPEEAKEHFFELKSELEIDEHNLALFIKSVILLDL
CCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
VEESLKTKNLFEALMNYSGEDQWIKFYLLLLSFKNKRRILEVLEELLYMEKKVEDKLLLP
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHH
KIYGLIAEIYEEIGEIKGHQFLDKAYKLNPQDLYILRLKLKYGLISEEEKQNLKLYRLFP
HHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCCCEEEEECC
EDSKLINEYYHKTRKNFNSIHNFKFFCWGGDNIGASSYLVSYEGINILLDAGALIKDKTL
CHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEEEECCEEEEEECCCEEECCEE
YYNSIKNLPIDIKDIDLVIITHVHLDHSGGIVELLRKGLNSPIIISRPTKEILKQIFLRG
EECCCCCCCCEEECCCEEEEEEEEECCCCCHHHHHHHCCCCCEEEECCHHHHHHHHHHCC
HTKLEVKIEEEIINFDSQIISFDTEEESSFRIKNKEVKLKLFPAGHILGAVAVYLEIDGI
CCEEEEEEHHHHHCCCCCEEEECCCCCCCEEEECCEEEEEEECCHHHHEEEEEEEEECCE
KIFYTGDFTLKDVESNKGLRFLPDLKVDILITEATYGYGNNFGVQNKYLQDKLILKSIEK
EEEEECCEEEEECCCCCCEEECCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
LLKDEERILLPVYAIGKGQDLLLFFRKTFSYIPFNVYVDGDIAYFSKLYENFAGPIYGNG
HHCCCCEEEEEEEEECCCCHHHHEEHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCCCCC
ILNVAGNTLYTDRKDFIKKEIALGNCVILASSNDLKEGSASFIYAFEIKNFSKGCIMNLD
EEEECCCEEECCHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEEECCCCCCEEEEEC
TNNREIEGLKNYQIGMLNHANMVDLLETVIKMAPSAVFVIHRGYESKSEINIETILKRIE
CCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHC
GIKVFAPKEGEIIELQ
CCEEECCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]