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The map label for this gene is mpg1 [H]

Identifier: 167039663

GI number: 167039663

Start: 1043772

End: 1046102

Strand: Direct

Name: mpg1 [H]

Synonym: Teth514_1013

Alternate gene names: 167039663

Gene position: 1043772-1046102 (Clockwise)

Preceding gene: 167039660

Following gene: 167039664

Centisome position: 42.48

GC content: 32.22

Gene sequence:

>2331_bases
ATGAAAGGGATAATCATGGCGGGTGGAGAAGGAAGTAGACTAAGACCTTTAACAGCCGATATACCTAAGCCTATGGTACC
TGTTGCAAATAAACCTGCGATAAAGCACATAGTGGAACACTTACACAAATATGGAATCAAAGATTTAGCTGTTACGCTTT
TTTACTTGCCTCAAAAGATTAAAAAATATTTAGAAGAAGAATATGGGGATGAAATAAAGTTTTATATAGAGGATAAGCCG
TTAGGGACGGCAGGCAGTGTCAAAAATGCTAGAGACTTTCTAAATGATACTTTTATTGTTATGAGCGGAGATGTAATTAC
TGATGTTAATATAAAAGAAGCTTATGAGTTTCACAGAAAGAAAGGGGCAAAAGTTACTCTTATTTTGACAAGAGTAGATG
TGCCGTTGGAATATGGTGTTGTGATTGTGGATGAGGAAGGCAAAATAAAAAAATTTTTAGAGAAACCTTCTTGGGGAGAA
GTGTTTAGCGATACAGTAAATACGGGTATATACATAATAGAACCAGAAATATTGGAGTTTATACCTCAAGATAAGCCTTT
TGATTTTAGTAAAGATTTATTTCCTATGTTGTTGAAAAATGATATTCCAATGTACGGTTATATTACAGGAGGATATTGGT
GTGATATAGGAAATACCAATCAATACATCACTAGTCATTTTGATATTTTAGAAGGAAGAGTAGATTTAGGATATAAGGAT
AAGTTACTTAAAAAGGGAAAGGTAATAGGCAAAAATGTTACAATTTCTCCTGAAGCTAAAATCATCCCTCCTGTGATTAT
AGGAGACAATGCAATAATTGAAGCTAACGCTGTTGTAGGACCTAACGTAATAATTGGTAAAAATAACTATATAAAGAAAG
GGAGCAGTTTAAAAAATGCTGTATTGTGGGATGAAATAATTGTAGATAAAAATTGTGAATTAAGGGGTTGTGTAGTTTGC
AATAGAGTGAGAATCGGCAATAATGTCCGAATTTTTGAAAACAGTGTTATAGGGGAGAGTTGTAAAATAAAATCCTTTGC
TGAAATAAAGCCAGAGGTAAAAATATGGCCCTATAAAATAATAGATGAGGGCTCTGTGATCACAAAAGATGTAGTGTGGG
GGAATGGAAGGAAGCCTTTGACTTTTGGGTATAGGGGGATTAAAGGAGTTTTTAATGAGGATATTACTCCTCAAATTGCA
GTTGAAATTGGAGAAGTTTTTGGAAATATAGTGAATAGCAGTGTGTTGGTAGGACACGATGGGGATATTGTATCTCAATT
TATAAGCGATTTAATAAGTTTTGGGCTTGTATCTGGTGGTTGTGAGGTCTTAAAAGTCAATAATACTCTTTTACCCACTT
TAAGATATGGAATTAAGAAAAATAAGTGTGGAGGAGGAATCTATGTAGAGGAAGAAGAAGGAAATTTAAGGATTTTGTTT
CTCGATAAAGAAGGGTGTGATATCGATAGAAACTTAGAAAAGAAAATAGAGAACAAATTGAGAGTATATGATATTGAACG
AGTTGATGGGAAAAATTTAAAATCTATAAGAGAAATTGATATAAACAATGATTATCTTAACTTTCTTTTTAAAAAAAGGA
CTGCCTATAAAAGTTTTAAAATTAAACCTTACGATGAAAAAACAAAACTGCTATTAGAAGCCGTAGGTAAAAATGAGTTT
TTTATAACGCAAGAGTCTTATGATGTAGGGGTGCTTTTTTATAAAAATGGGGAAAAAGTTAAACTCTACGACGAAAAGGG
AAGAGAATTTGATGAGGATGAACTTGAGTTTATAAGAATGTTAATTGCTAAAGAGCAAGGGGCCAAAAATTTTGTACTTC
CTTTCGATAGTTCCAAATACTTGACAGAATTTGCGAAGGAATTTGCTATTGAGACTGTAAGCAGCAAAATTTCCCATAAA
GATAGAATGAAAACAATAGTGTCGAAGGAAGGCGTAGAAAAAGATCTACAGATTAATTTAAATTTTGACGGATTTAGTTT
TTTACTAGACCTTTTAGAATATTTACAACATACCTCTCAAAAACTTTCCTCTATAAAAGATAGTTTTCCTTTAAGATATA
GAATAACCAAAAGTATAAAATGCGATTGGAGAGATAAAGGAAAAATAATAAGAATGCTTTTTGAAAAGGCCGATGGAGGG
GCAGAATTTTTAGATGGTTTAAAGTTTAATAAAGAAGATTCATGGGTGTTAGTAGTACCGGATTATGAATTACCTGCTTG
TAATATTTATATAGAAGCTCCTACAAAAGAAAGAGCTGAAGAGTTATTTTCAATGTATGAAAAAGAAATTAAAAGTATTG
TACAAAAGTAA

Upstream 100 bases:

>100_bases
ATTTCAATTTTATGTTGCCAATGTCTTAAAATGAATAATTTTTCATTAAATAAAAAACACTAAGAATTAGAGGTTAATAA
TATTTTTTAGAGGTGGTTGG

Downstream 100 bases:

>100_bases
AATTTTATTTGAAGTTTGCGAGACAAAGAGACGTAGGCGGGGCCGGATGCAAGGATGCCGGAGGCTGGCCTTATGCACGC
ACTACAGTTTGAAGCGGGTT

Product: nucleotidyl transferase

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 776; Mature: 776

Protein sequence:

>776_residues
MKGIIMAGGEGSRLRPLTADIPKPMVPVANKPAIKHIVEHLHKYGIKDLAVTLFYLPQKIKKYLEEEYGDEIKFYIEDKP
LGTAGSVKNARDFLNDTFIVMSGDVITDVNIKEAYEFHRKKGAKVTLILTRVDVPLEYGVVIVDEEGKIKKFLEKPSWGE
VFSDTVNTGIYIIEPEILEFIPQDKPFDFSKDLFPMLLKNDIPMYGYITGGYWCDIGNTNQYITSHFDILEGRVDLGYKD
KLLKKGKVIGKNVTISPEAKIIPPVIIGDNAIIEANAVVGPNVIIGKNNYIKKGSSLKNAVLWDEIIVDKNCELRGCVVC
NRVRIGNNVRIFENSVIGESCKIKSFAEIKPEVKIWPYKIIDEGSVITKDVVWGNGRKPLTFGYRGIKGVFNEDITPQIA
VEIGEVFGNIVNSSVLVGHDGDIVSQFISDLISFGLVSGGCEVLKVNNTLLPTLRYGIKKNKCGGGIYVEEEEGNLRILF
LDKEGCDIDRNLEKKIENKLRVYDIERVDGKNLKSIREIDINNDYLNFLFKKRTAYKSFKIKPYDEKTKLLLEAVGKNEF
FITQESYDVGVLFYKNGEKVKLYDEKGREFDEDELEFIRMLIAKEQGAKNFVLPFDSSKYLTEFAKEFAIETVSSKISHK
DRMKTIVSKEGVEKDLQINLNFDGFSFLLDLLEYLQHTSQKLSSIKDSFPLRYRITKSIKCDWRDKGKIIRMLFEKADGG
AEFLDGLKFNKEDSWVLVVPDYELPACNIYIEAPTKERAEELFSMYEKEIKSIVQK

Sequences:

>Translated_776_residues
MKGIIMAGGEGSRLRPLTADIPKPMVPVANKPAIKHIVEHLHKYGIKDLAVTLFYLPQKIKKYLEEEYGDEIKFYIEDKP
LGTAGSVKNARDFLNDTFIVMSGDVITDVNIKEAYEFHRKKGAKVTLILTRVDVPLEYGVVIVDEEGKIKKFLEKPSWGE
VFSDTVNTGIYIIEPEILEFIPQDKPFDFSKDLFPMLLKNDIPMYGYITGGYWCDIGNTNQYITSHFDILEGRVDLGYKD
KLLKKGKVIGKNVTISPEAKIIPPVIIGDNAIIEANAVVGPNVIIGKNNYIKKGSSLKNAVLWDEIIVDKNCELRGCVVC
NRVRIGNNVRIFENSVIGESCKIKSFAEIKPEVKIWPYKIIDEGSVITKDVVWGNGRKPLTFGYRGIKGVFNEDITPQIA
VEIGEVFGNIVNSSVLVGHDGDIVSQFISDLISFGLVSGGCEVLKVNNTLLPTLRYGIKKNKCGGGIYVEEEEGNLRILF
LDKEGCDIDRNLEKKIENKLRVYDIERVDGKNLKSIREIDINNDYLNFLFKKRTAYKSFKIKPYDEKTKLLLEAVGKNEF
FITQESYDVGVLFYKNGEKVKLYDEKGREFDEDELEFIRMLIAKEQGAKNFVLPFDSSKYLTEFAKEFAIETVSSKISHK
DRMKTIVSKEGVEKDLQINLNFDGFSFLLDLLEYLQHTSQKLSSIKDSFPLRYRITKSIKCDWRDKGKIIRMLFEKADGG
AEFLDGLKFNKEDSWVLVVPDYELPACNIYIEAPTKERAEELFSMYEKEIKSIVQK
>Mature_776_residues
MKGIIMAGGEGSRLRPLTADIPKPMVPVANKPAIKHIVEHLHKYGIKDLAVTLFYLPQKIKKYLEEEYGDEIKFYIEDKP
LGTAGSVKNARDFLNDTFIVMSGDVITDVNIKEAYEFHRKKGAKVTLILTRVDVPLEYGVVIVDEEGKIKKFLEKPSWGE
VFSDTVNTGIYIIEPEILEFIPQDKPFDFSKDLFPMLLKNDIPMYGYITGGYWCDIGNTNQYITSHFDILEGRVDLGYKD
KLLKKGKVIGKNVTISPEAKIIPPVIIGDNAIIEANAVVGPNVIIGKNNYIKKGSSLKNAVLWDEIIVDKNCELRGCVVC
NRVRIGNNVRIFENSVIGESCKIKSFAEIKPEVKIWPYKIIDEGSVITKDVVWGNGRKPLTFGYRGIKGVFNEDITPQIA
VEIGEVFGNIVNSSVLVGHDGDIVSQFISDLISFGLVSGGCEVLKVNNTLLPTLRYGIKKNKCGGGIYVEEEEGNLRILF
LDKEGCDIDRNLEKKIENKLRVYDIERVDGKNLKSIREIDINNDYLNFLFKKRTAYKSFKIKPYDEKTKLLLEAVGKNEF
FITQESYDVGVLFYKNGEKVKLYDEKGREFDEDELEFIRMLIAKEQGAKNFVLPFDSSKYLTEFAKEFAIETVSSKISHK
DRMKTIVSKEGVEKDLQINLNFDGFSFLLDLLEYLQHTSQKLSSIKDSFPLRYRITKSIKCDWRDKGKIIRMLFEKADGG
AEFLDGLKFNKEDSWVLVVPDYELPACNIYIEAPTKERAEELFSMYEKEIKSIVQK

Specific function: Glycogen biosynthesis; first step. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=347, Percent_Identity=33.7175792507205, Blast_Score=192, Evalue=9e-49,
Organism=Homo sapiens, GI11761619, Length=340, Percent_Identity=33.2352941176471, Blast_Score=186, Evalue=5e-47,
Organism=Homo sapiens, GI31881779, Length=355, Percent_Identity=28.4507042253521, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI45447090, Length=355, Percent_Identity=28.4507042253521, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI9966779, Length=134, Percent_Identity=31.3432835820896, Blast_Score=71, Evalue=5e-12,
Organism=Homo sapiens, GI262205273, Length=134, Percent_Identity=31.3432835820896, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI1789837, Length=391, Percent_Identity=23.0179028132992, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1788351, Length=192, Percent_Identity=26.5625, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790224, Length=194, Percent_Identity=26.2886597938144, Blast_Score=66, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI133931050, Length=351, Percent_Identity=32.7635327635328, Blast_Score=179, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI17509979, Length=350, Percent_Identity=25.7142857142857, Blast_Score=115, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI17509981, Length=338, Percent_Identity=25.4437869822485, Blast_Score=108, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6320148, Length=375, Percent_Identity=33.3333333333333, Blast_Score=190, Evalue=8e-49,
Organism=Drosophila melanogaster, GI21355443, Length=349, Percent_Identity=35.5300859598854, Blast_Score=185, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24644084, Length=349, Percent_Identity=35.5300859598854, Blast_Score=185, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24653912, Length=372, Percent_Identity=23.1182795698925, Blast_Score=105, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 88254; Mature: 88254

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGIIMAGGEGSRLRPLTADIPKPMVPVANKPAIKHIVEHLHKYGIKDLAVTLFYLPQKI
CCCEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
KKYLEEEYGDEIKFYIEDKPLGTAGSVKNARDFLNDTFIVMSGDVITDVNIKEAYEFHRK
HHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHCCEEEEEECCEEECCCHHHHHHHHHH
KGAKVTLILTRVDVPLEYGVVIVDEEGKIKKFLEKPSWGEVFSDTVNTGIYIIEPEILEF
CCCEEEEEEEEECCCCCCCEEEECCCCHHHHHHCCCCCHHHHHHHHHCCEEEECHHHHHH
IPQDKPFDFSKDLFPMLLKNDIPMYGYITGGYWCDIGNTNQYITSHFDILEGRVDLGYKD
CCCCCCCCCCHHHHHHHHHCCCCEEEEEECCEEEECCCCCCHHHHHHHHHCCCCCCCHHH
KLLKKGKVIGKNVTISPEAKIIPPVIIGDNAIIEANAVVGPNVIIGKNNYIKKGSSLKNA
HHHHCCCEECCCEEECCCCCCCCEEEECCCEEEEECCEECCEEEECCCCCCCCCCCCCHH
VLWDEIIVDKNCELRGCVVCNRVRIGNNVRIFENSVIGESCKIKSFAEIKPEVKIWPYKI
HHHHHHEECCCCCEEEEEEEEEEEECCEEEEEECCCCCCCCCCCHHHHCCCCEEEEEEEE
IDEGSVITKDVVWGNGRKPLTFGYRGIKGVFNEDITPQIAVEIGEVFGNIVNSSVLVGHD
ECCCCEEEEEEEECCCCCCEEECCCCCCHHCCCCCCHHHHHHHHHHHHHHHCCCEEEECC
GDIVSQFISDLISFGLVSGGCEVLKVNNTLLPTLRYGIKKNKCGGGIYVEEEEGNLRILF
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHCCCCCCCCCCEEEEECCCCEEEEE
LDKEGCDIDRNLEKKIENKLRVYDIERVDGKNLKSIREIDINNDYLNFLFKKRTAYKSFK
ECCCCCCCCCHHHHHHHCCEEEEEEEECCCCCCCHHEEECCCCHHHHHHHHHHHHCCCEE
IKPYDEKTKLLLEAVGKNEFFITQESYDVGVLFYKNGEKVKLYDEKGREFDEDELEFIRM
ECCCCHHHHHHHHHCCCCCEEEEECCCCEEEEEEECCCEEEEEECCCCCCCHHHHHHHHH
LIAKEQGAKNFVLPFDSSKYLTEFAKEFAIETVSSKISHKDRMKTIVSKEGVEKDLQINL
HHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
NFDGFSFLLDLLEYLQHTSQKLSSIKDSFPLRYRITKSIKCDWRDKGKIIRMLFEKADGG
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCEECCCCCCCHHHHHHHHHCCCC
AEFLDGLKFNKEDSWVLVVPDYELPACNIYIEAPTKERAEELFSMYEKEIKSIVQK
HHHHHCCCCCCCCCEEEEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKGIIMAGGEGSRLRPLTADIPKPMVPVANKPAIKHIVEHLHKYGIKDLAVTLFYLPQKI
CCCEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
KKYLEEEYGDEIKFYIEDKPLGTAGSVKNARDFLNDTFIVMSGDVITDVNIKEAYEFHRK
HHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHCCEEEEEECCEEECCCHHHHHHHHHH
KGAKVTLILTRVDVPLEYGVVIVDEEGKIKKFLEKPSWGEVFSDTVNTGIYIIEPEILEF
CCCEEEEEEEEECCCCCCCEEEECCCCHHHHHHCCCCCHHHHHHHHHCCEEEECHHHHHH
IPQDKPFDFSKDLFPMLLKNDIPMYGYITGGYWCDIGNTNQYITSHFDILEGRVDLGYKD
CCCCCCCCCCHHHHHHHHHCCCCEEEEEECCEEEECCCCCCHHHHHHHHHCCCCCCCHHH
KLLKKGKVIGKNVTISPEAKIIPPVIIGDNAIIEANAVVGPNVIIGKNNYIKKGSSLKNA
HHHHCCCEECCCEEECCCCCCCCEEEECCCEEEEECCEECCEEEECCCCCCCCCCCCCHH
VLWDEIIVDKNCELRGCVVCNRVRIGNNVRIFENSVIGESCKIKSFAEIKPEVKIWPYKI
HHHHHHEECCCCCEEEEEEEEEEEECCEEEEEECCCCCCCCCCCHHHHCCCCEEEEEEEE
IDEGSVITKDVVWGNGRKPLTFGYRGIKGVFNEDITPQIAVEIGEVFGNIVNSSVLVGHD
ECCCCEEEEEEEECCCCCCEEECCCCCCHHCCCCCCHHHHHHHHHHHHHHHCCCEEEECC
GDIVSQFISDLISFGLVSGGCEVLKVNNTLLPTLRYGIKKNKCGGGIYVEEEEGNLRILF
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHCCCCCCCCCCEEEEECCCCEEEEE
LDKEGCDIDRNLEKKIENKLRVYDIERVDGKNLKSIREIDINNDYLNFLFKKRTAYKSFK
ECCCCCCCCCHHHHHHHCCEEEEEEEECCCCCCCHHEEECCCCHHHHHHHHHHHHCCCEE
IKPYDEKTKLLLEAVGKNEFFITQESYDVGVLFYKNGEKVKLYDEKGREFDEDELEFIRM
ECCCCHHHHHHHHHCCCCCEEEEECCCCEEEEEEECCCEEEEEECCCCCCCHHHHHHHHH
LIAKEQGAKNFVLPFDSSKYLTEFAKEFAIETVSSKISHKDRMKTIVSKEGVEKDLQINL
HHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
NFDGFSFLLDLLEYLQHTSQKLSSIKDSFPLRYRITKSIKCDWRDKGKIIRMLFEKADGG
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCEECCCCCCCHHHHHHHHHCCCC
AEFLDGLKFNKEDSWVLVVPDYELPACNIYIEAPTKERAEELFSMYEKEIKSIVQK
HHHHHCCCCCCCCCEEEEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]