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The map label for this gene is alr2 [H]

Identifier: 167039616

GI number: 167039616

Start: 985226

End: 986392

Strand: Direct

Name: alr2 [H]

Synonym: Teth514_0964

Alternate gene names: 167039616

Gene position: 985226-986392 (Clockwise)

Preceding gene: 167039615

Following gene: 167039617

Centisome position: 40.09

GC content: 32.48

Gene sequence:

>1167_bases
ATGTTTGATAATATAAGGCCAACAAGAGCAGAAATATATTTGGATAATATAGTGCATAATTTGAGTGAAGTAAAGAGATG
GGTGGGGAAGAAAGTAAAAATAATGGGGGTAGTGAAAGCCAATGCTTATGGTCATGGAGCTTGTCAAGTAGCAAAGGTTT
TAATAGAAAATGGGGTTTCTTATTTGGGAGTAGCTACAATAGAAGAGGCGTTAGAATTAAGGGAATGCGGAATTAATATT
CCCATACTCGTTTTTGGATATACGCCTTTACCTCAGGCCAAAGAATTAATTGTGCACAATATAACTCAAACTGTTTTTGA
TATAAACTATGTTAAAGACTTAGAAAGAATTGCCTTAAATGTGGGTAAGAAGGCTAAAGTTCATGTAAAAGTTGATACAG
GTATGGGACGGATAGGATATACAGATTTAAATGTAGCTGAAAAAGAGATAGAAAAAATGATGGAAATGGAAGGGGTAGAG
GTAGAAGGCATATTTAGTCATTTTGCTACTTCTGATGAAAAAGATAAAACATATGCTGAACAACAGTTTGATATGTTCAA
GAAATTGTTAGAAAGCTTAAAGCAAAAAGAGATAAACATTCCTTTAAAGCATATAGCTAACAGTGGAGCAATTATTGACC
TTAAATATACTTATTTAGACATGGTAAGGCCAGGAATAGTTCTATACGGTAGTTATCCTTCAGAAAATGTTGAAAGACCA
TTGGATTTAAGACAGACTATGGGTTTTAAAACTAAAATAGTGTATATAAAAGAAGTACCTGAAGGTACTTCCATTAGTTA
TGGAAGGACATTTATAACTAAAAGAAAAAGCAAAATTGCCACATTGCCTGTAGGATATGCTGATGGTTTTAATAGATTAC
TCTCTAATAATCATCATGTCTTAGTAAAAGGGAAATATGCTCCCGTAATTGGGAGAATTTGTATGGACCAAACGATGTTA
GATGTCACCGATATAGAAGGAGTAGAAGTAGGTGATGATGTAACTATTTTTGGAAATCAAGATGGAGAAAAAATAACAGC
AGAGGAGATTGCTAAAAAATTAAATACTATACCTTATGAAGTATATTGTGGAATATCTAGAAGGGTACCTCGAATATATA
TTTACAAAGGAGAGGTAATTGAGGTAAAAAATTATTTAAAAATTTGA

Upstream 100 bases:

>100_bases
TGGTATTCAAATAAAAATTACAGTAACAGGAGATTTGAGTGAAGAAGAGATACTTAAGGTGATAAAATCCTTGAGGTGAA
AAACAAAAGGGGGATTTTTA

Downstream 100 bases:

>100_bases
CTTTTATAGTATAAAATTTACAAATGATTGACATCATTATATATAGTAATATATAATAAATTATATAAGTGCGTAAGGAG
GTCCTAAAAGTGGGCGAAAC

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MFDNIRPTRAEIYLDNIVHNLSEVKRWVGKKVKIMGVVKANAYGHGACQVAKVLIENGVSYLGVATIEEALELRECGINI
PILVFGYTPLPQAKELIVHNITQTVFDINYVKDLERIALNVGKKAKVHVKVDTGMGRIGYTDLNVAEKEIEKMMEMEGVE
VEGIFSHFATSDEKDKTYAEQQFDMFKKLLESLKQKEINIPLKHIANSGAIIDLKYTYLDMVRPGIVLYGSYPSENVERP
LDLRQTMGFKTKIVYIKEVPEGTSISYGRTFITKRKSKIATLPVGYADGFNRLLSNNHHVLVKGKYAPVIGRICMDQTML
DVTDIEGVEVGDDVTIFGNQDGEKITAEEIAKKLNTIPYEVYCGISRRVPRIYIYKGEVIEVKNYLKI

Sequences:

>Translated_388_residues
MFDNIRPTRAEIYLDNIVHNLSEVKRWVGKKVKIMGVVKANAYGHGACQVAKVLIENGVSYLGVATIEEALELRECGINI
PILVFGYTPLPQAKELIVHNITQTVFDINYVKDLERIALNVGKKAKVHVKVDTGMGRIGYTDLNVAEKEIEKMMEMEGVE
VEGIFSHFATSDEKDKTYAEQQFDMFKKLLESLKQKEINIPLKHIANSGAIIDLKYTYLDMVRPGIVLYGSYPSENVERP
LDLRQTMGFKTKIVYIKEVPEGTSISYGRTFITKRKSKIATLPVGYADGFNRLLSNNHHVLVKGKYAPVIGRICMDQTML
DVTDIEGVEVGDDVTIFGNQDGEKITAEEIAKKLNTIPYEVYCGISRRVPRIYIYKGEVIEVKNYLKI
>Mature_388_residues
MFDNIRPTRAEIYLDNIVHNLSEVKRWVGKKVKIMGVVKANAYGHGACQVAKVLIENGVSYLGVATIEEALELRECGINI
PILVFGYTPLPQAKELIVHNITQTVFDINYVKDLERIALNVGKKAKVHVKVDTGMGRIGYTDLNVAEKEIEKMMEMEGVE
VEGIFSHFATSDEKDKTYAEQQFDMFKKLLESLKQKEINIPLKHIANSGAIIDLKYTYLDMVRPGIVLYGSYPSENVERP
LDLRQTMGFKTKIVYIKEVPEGTSISYGRTFITKRKSKIATLPVGYADGFNRLLSNNHHVLVKGKYAPVIGRICMDQTML
DVTDIEGVEVGDDVTIFGNQDGEKITAEEIAKKLNTIPYEVYCGISRRVPRIYIYKGEVIEVKNYLKI

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=360, Percent_Identity=30, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1787439, Length=376, Percent_Identity=27.6595744680851, Blast_Score=142, Evalue=5e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 43793; Mature: 43793

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDNIRPTRAEIYLDNIVHNLSEVKRWVGKKVKIMGVVKANAYGHGACQVAKVLIENGVS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCCHHHHHHHHHHHCCCH
YLGVATIEEALELRECGINIPILVFGYTPLPQAKELIVHNITQTVFDINYVKDLERIALN
HEEHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VGKKAKVHVKVDTGMGRIGYTDLNVAEKEIEKMMEMEGVEVEGIFSHFATSDEKDKTYAE
CCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHH
QQFDMFKKLLESLKQKEINIPLKHIANSGAIIDLKYTYLDMVRPGIVLYGSYPSENVERP
HHHHHHHHHHHHHHHCCCCCCHHHHCCCCCEEEEEHHHHHHCCCCEEEEECCCCCCCCCC
LDLRQTMGFKTKIVYIKEVPEGTSISYGRTFITKRKSKIATLPVGYADGFNRLLSNNHHV
HHHHHHCCCEEEEEEEEECCCCCCCCCCHHHHHHHCCCEEEEECCHHHHHHHHHCCCCEE
LVKGKYAPVIGRICMDQTMLDVTDIEGVEVGDDVTIFGNQDGEKITAEEIAKKLNTIPYE
EEEECCCHHHHHHHHCCHHEEEECCCCEECCCCEEEEECCCCCEECHHHHHHHHCCCCEE
VYCGISRRVPRIYIYKGEVIEVKNYLKI
EEECCCCCCCEEEEEECCEEEECHHHCC
>Mature Secondary Structure
MFDNIRPTRAEIYLDNIVHNLSEVKRWVGKKVKIMGVVKANAYGHGACQVAKVLIENGVS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCCHHHHHHHHHHHCCCH
YLGVATIEEALELRECGINIPILVFGYTPLPQAKELIVHNITQTVFDINYVKDLERIALN
HEEHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VGKKAKVHVKVDTGMGRIGYTDLNVAEKEIEKMMEMEGVEVEGIFSHFATSDEKDKTYAE
CCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHH
QQFDMFKKLLESLKQKEINIPLKHIANSGAIIDLKYTYLDMVRPGIVLYGSYPSENVERP
HHHHHHHHHHHHHHHCCCCCCHHHHCCCCCEEEEEHHHHHHCCCCEEEEECCCCCCCCCC
LDLRQTMGFKTKIVYIKEVPEGTSISYGRTFITKRKSKIATLPVGYADGFNRLLSNNHHV
HHHHHHCCCEEEEEEEEECCCCCCCCCCHHHHHHHCCCEEEEECCHHHHHHHHHCCCCEE
LVKGKYAPVIGRICMDQTMLDVTDIEGVEVGDDVTIFGNQDGEKITAEEIAKKLNTIPYE
EEEECCCHHHHHHHHCCHHEEEECCCCEECCCCEEEEECCCCCEECHHHHHHHHCCCCEE
VYCGISRRVPRIYIYKGEVIEVKNYLKI
EEECCCCCCCEEEEEECCEEEECHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]