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The map label for this gene is acpS

Identifier: 167039613

GI number: 167039613

Start: 982271

End: 982687

Strand: Direct

Name: acpS

Synonym: Teth514_0961

Alternate gene names: 167039613

Gene position: 982271-982687 (Clockwise)

Preceding gene: 167039612

Following gene: 167039614

Centisome position: 39.97

GC content: 34.77

Gene sequence:

>417_bases
ATGGAACTGTTTGTGGGAACGGATATTGTAGAAGTTGAAAGGATAAAAAAAGCTTTTGATGCAAATTCTAAATTTTTGGA
ACGGTTATTTACTCAAAAAGAGATAGAGTATTTTAACAGTAAAAGGATGAAATTACCTCATATAGCGGGTTTTTTTTCAG
CAAAAGAAAGCATATCAAAAGTCTTAGGAACAGGTATCAGTGGTTTTAGCTGGAAAGATATTGAAATATGTCACGATGAA
AAAGGAGCCCCTGCCGTAATTTTAAAGGGGAAGGCTAAAAATATTGCAGACAAAAAGGGAATAAGGGATATAAAGCTGTC
TATTTCTCATACGAAGACCTATGCTATAAGCTGTGCTATTGCTATTGGAGGTGAAAAAAATGATAGTGCTGACCTCAAAA
CAGATGAGAGGAGTTGA

Upstream 100 bases:

>100_bases
TTTAAGAAGGTGTCATGCCTTCTTTTATTTTTTTGAAGGATTTTGTGAATTAATAGAGAAATAATATAATGTAATTAGGA
TAATTGGAGGAACTGTATAT

Downstream 100 bases:

>100_bases
AAAAATAGCTATAGAAAAAATAGGAATTCCTTCTATAGGTTTAATGGAGAATGCGGGAAGAGAAACAGCGCTAGAGGTAA
AAAAGATTTTAGAGGAAGAG

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 138; Mature: 138

Protein sequence:

>138_residues
MELFVGTDIVEVERIKKAFDANSKFLERLFTQKEIEYFNSKRMKLPHIAGFFSAKESISKVLGTGISGFSWKDIEICHDE
KGAPAVILKGKAKNIADKKGIRDIKLSISHTKTYAISCAIAIGGEKNDSADLKTDERS

Sequences:

>Translated_138_residues
MELFVGTDIVEVERIKKAFDANSKFLERLFTQKEIEYFNSKRMKLPHIAGFFSAKESISKVLGTGISGFSWKDIEICHDE
KGAPAVILKGKAKNIADKKGIRDIKLSISHTKTYAISCAIAIGGEKNDSADLKTDERS
>Mature_138_residues
MELFVGTDIVEVERIKKAFDANSKFLERLFTQKEIEYFNSKRMKLPHIAGFFSAKESISKVLGTGISGFSWKDIEICHDE
KGAPAVILKGKAKNIADKKGIRDIKLSISHTKTYAISCAIAIGGEKNDSADLKTDERS

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=122, Percent_Identity=30.327868852459, Blast_Score=63, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6325025, Length=114, Percent_Identity=42.1052631578947, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_THEP3 (B0KD52)

Other databases:

- EMBL:   CP000924
- RefSeq:   YP_001664486.1
- ProteinModelPortal:   B0KD52
- SMR:   B0KD52
- GeneID:   5874050
- GenomeReviews:   CP000924_GR
- KEGG:   tpd:Teth39_0484
- HOGENOM:   HBG734479
- OMA:   NSSAIAY
- ProtClustDB:   PRK00070
- BioCyc:   TPSE340099:TETH39_0484-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 15326; Mature: 15326

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELFVGTDIVEVERIKKAFDANSKFLERLFTQKEIEYFNSKRMKLPHIAGFFSAKESISK
CEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
VLGTGISGFSWKDIEICHDEKGAPAVILKGKAKNIADKKGIRDIKLSISHTKTYAISCAI
HHHCCCCCCCCCCEEEEECCCCCCEEEEECCCCCCCCCCCCEEEEEEEECCEEEEEEEEE
AIGGEKNDSADLKTDERS
EECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MELFVGTDIVEVERIKKAFDANSKFLERLFTQKEIEYFNSKRMKLPHIAGFFSAKESISK
CEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
VLGTGISGFSWKDIEICHDEKGAPAVILKGKAKNIADKKGIRDIKLSISHTKTYAISCAI
HHHCCCCCCCCCCEEEEECCCCCCEEEEECCCCCCCCCCCCEEEEEEEECCEEEEEEEEE
AIGGEKNDSADLKTDERS
EECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA