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The map label for this gene is trxB [H]

Identifier: 167039576

GI number: 167039576

Start: 945866

End: 946780

Strand: Direct

Name: trxB [H]

Synonym: Teth514_0924

Alternate gene names: 167039576

Gene position: 945866-946780 (Clockwise)

Preceding gene: 167039575

Following gene: 167039578

Centisome position: 38.49

GC content: 37.7

Gene sequence:

>915_bases
ATGTACGATCTAATTATTTTAGGAGGAGGTCCTGCGGGACTTACTGCTGGATTGTATGCTGCAAGGTCAAGGCTTAAAAC
GGTACTTATTGAAAAAACTTATCTGGGAGGGCAAATAGTAAATACTTATCAGTTAGAAAATTACCCGGGTTATGAAGAGA
TAAGTGGTGCTGACCTTATTGCCAAGATGGAGGCACAGGTGAGAAAACACGGCCTTGAGATTGTTAATGAAGATGTTGAG
AGTCTAGATATTACAGGAGATGTAAAGAAAGTTAAGACTTCTAATAAAACTTATGAAGCAAAAGCTATTATTTTAGCGAT
GGGCGCTACACCTAAAAAGTTAGGTGTTCCAAATGAGGATAGATTTATAGGGGCAGGTATCTCCTTCTGTGCTACCTGTG
ACGGAGCTTTTTACAGAGATGCCACAGTGGCAGTTATAGGCGGAGGAAATACAGCAGTAGAAGACGCGTTATACCTTACT
AAATTTGCAAAAAAAGTCTATATAATTCATAGAAGAAATGAACTTAGAGCTACAAAGATTGAACAGGAAAAAGCCTTCGC
AAATGAAAAAATTGAGTTTATTTGGGATACTGTAGTAGTTGATGTAGAGGGAGAGTATGGAGTAGAAAGACTCAAACTTA
AAAATGTTAAAACAGGAGAAGAAAGCACACTAAACGTAGATGGTGTCTTTGTAGCTATTGGATATGCTCCTAATACAGAA
TTGGTGAAAGGCATAGTAGACCTTGATGAATATGGATATATCATGACAGATGATGATATGAGGACAAATATACCTGGAGT
TTTTGCAGCTGGAGACATAAGGCATAAATCTTTAAGACAAGTTATAACGGCTGCTGGAGATGGCGCAATAGCGGCTTATG
TAGCAGAAAAATATATAGACAGCCTAAAAAAATAG

Upstream 100 bases:

>100_bases
GGATGATGTAAATATAAAAAGTTTGTGATATAATAATGGAAGTAGTGTTTTTACTACTTCCATTATTATATTTTATTTTC
AAAGGAGGAGTGATTTTATT

Downstream 100 bases:

>100_bases
TCAGGATTTTTCCTGACTATTTTTCACTTTATTCTTCTTGCTCTTGTTCTTGTTCTGCATTTATTTCTTGTACTTCTTGG
TTATAGACTATTTCTTGTGA

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MYDLIILGGGPAGLTAGLYAARSRLKTVLIEKTYLGGQIVNTYQLENYPGYEEISGADLIAKMEAQVRKHGLEIVNEDVE
SLDITGDVKKVKTSNKTYEAKAIILAMGATPKKLGVPNEDRFIGAGISFCATCDGAFYRDATVAVIGGGNTAVEDALYLT
KFAKKVYIIHRRNELRATKIEQEKAFANEKIEFIWDTVVVDVEGEYGVERLKLKNVKTGEESTLNVDGVFVAIGYAPNTE
LVKGIVDLDEYGYIMTDDDMRTNIPGVFAAGDIRHKSLRQVITAAGDGAIAAYVAEKYIDSLKK

Sequences:

>Translated_304_residues
MYDLIILGGGPAGLTAGLYAARSRLKTVLIEKTYLGGQIVNTYQLENYPGYEEISGADLIAKMEAQVRKHGLEIVNEDVE
SLDITGDVKKVKTSNKTYEAKAIILAMGATPKKLGVPNEDRFIGAGISFCATCDGAFYRDATVAVIGGGNTAVEDALYLT
KFAKKVYIIHRRNELRATKIEQEKAFANEKIEFIWDTVVVDVEGEYGVERLKLKNVKTGEESTLNVDGVFVAIGYAPNTE
LVKGIVDLDEYGYIMTDDDMRTNIPGVFAAGDIRHKSLRQVITAAGDGAIAAYVAEKYIDSLKK
>Mature_304_residues
MYDLIILGGGPAGLTAGLYAARSRLKTVLIEKTYLGGQIVNTYQLENYPGYEEISGADLIAKMEAQVRKHGLEIVNEDVE
SLDITGDVKKVKTSNKTYEAKAIILAMGATPKKLGVPNEDRFIGAGISFCATCDGAFYRDATVAVIGGGNTAVEDALYLT
KFAKKVYIIHRRNELRATKIEQEKAFANEKIEFIWDTVVVDVEGEYGVERLKLKNVKTGEESTLNVDGVFVAIGYAPNTE
LVKGIVDLDEYGYIMTDDDMRTNIPGVFAAGDIRHKSLRQVITAAGDGAIAAYVAEKYIDSLKK

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI65787454, Length=224, Percent_Identity=29.4642857142857, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI21389617, Length=224, Percent_Identity=29.4642857142857, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI226437568, Length=224, Percent_Identity=29.4642857142857, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1787114, Length=310, Percent_Identity=42.258064516129, Blast_Score=233, Evalue=1e-62,
Organism=Escherichia coli, GI87081763, Length=304, Percent_Identity=32.2368421052632, Blast_Score=155, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6320560, Length=314, Percent_Identity=42.3566878980892, Blast_Score=241, Evalue=1e-64,
Organism=Saccharomyces cerevisiae, GI6321898, Length=314, Percent_Identity=40.4458598726115, Blast_Score=227, Evalue=1e-60,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33165; Mature: 33165

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDLIILGGGPAGLTAGLYAARSRLKTVLIEKTYLGGQIVNTYQLENYPGYEEISGADLI
CEEEEEECCCCHHHHHHHHHHHHHHHHHEEEEEECCCEEEEEEEECCCCCHHHCCCCHHH
AKMEAQVRKHGLEIVNEDVESLDITGDVKKVKTSNKTYEAKAIILAMGATPKKLGVPNED
HHHHHHHHHHHHHHHCCCHHHEECCCCHHEEECCCCCEEEEEEEEEECCCCHHCCCCCCC
RFIGAGISFCATCDGAFYRDATVAVIGGGNTAVEDALYLTKFAKKVYIIHRRNELRATKI
CEEECCCCEEEECCCCEECCEEEEEEECCCHHHHHHHHHHHHHHEEEEEEECCCCCHHHH
EQEKAFANEKIEFIWDTVVVDVEGEYGVERLKLKNVKTGEESTLNVDGVFVAIGYAPNTE
HHHHHHHCCCEEEEEEEEEEEECCCCCCEEEEECCCCCCCCCEEEECEEEEEEECCCCHH
LVKGIVDLDEYGYIMTDDDMRTNIPGVFAAGDIRHKSLRQVITAAGDGAIAAYVAEKYID
HHHHHHHHHHCCCEEECCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
SLKK
HHCC
>Mature Secondary Structure
MYDLIILGGGPAGLTAGLYAARSRLKTVLIEKTYLGGQIVNTYQLENYPGYEEISGADLI
CEEEEEECCCCHHHHHHHHHHHHHHHHHEEEEEECCCEEEEEEEECCCCCHHHCCCCHHH
AKMEAQVRKHGLEIVNEDVESLDITGDVKKVKTSNKTYEAKAIILAMGATPKKLGVPNED
HHHHHHHHHHHHHHHCCCHHHEECCCCHHEEECCCCCEEEEEEEEEECCCCHHCCCCCCC
RFIGAGISFCATCDGAFYRDATVAVIGGGNTAVEDALYLTKFAKKVYIIHRRNELRATKI
CEEECCCCEEEECCCCEECCEEEEEEECCCHHHHHHHHHHHHHHEEEEEEECCCCCHHHH
EQEKAFANEKIEFIWDTVVVDVEGEYGVERLKLKNVKTGEESTLNVDGVFVAIGYAPNTE
HHHHHHHCCCEEEEEEEEEEEECCCCCCEEEEECCCCCCCCCEEEECEEEEEEECCCCHH
LVKGIVDLDEYGYIMTDDDMRTNIPGVFAAGDIRHKSLRQVITAAGDGAIAAYVAEKYID
HHHHHHHHHHCCCEEECCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
SLKK
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8529640 [H]