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The map label for this gene is 167039572

Identifier: 167039572

GI number: 167039572

Start: 943372

End: 944892

Strand: Direct

Name: 167039572

Synonym: Teth514_0920

Alternate gene names: NA

Gene position: 943372-944892 (Clockwise)

Preceding gene: 167039571

Following gene: 167039573

Centisome position: 38.39

GC content: 34.91

Gene sequence:

>1521_bases
ATGAAAATGAGAAAATTGACTCTTGAAGAGGAGAGGCTTTTAGAGAATTTTGTAACAGATGTATACGGACCCGTTTATTT
TATACATTCACTTCCAGAATTTATCATACCGCCTATAAATTCAAAAGTGAGTAGAAGAGACACCAGCTGGAGGCTTAATA
TACTTGAGTCTTTGACAGATGGAGATTTAAACATAACTGACTATATACCCAAACACAACATACCTTTAGAAAAAGCAATA
CAAAAAGCGAAAGAATTTCACGAAAAGTGGGTGGAAAGGTTTGGACATTCTTCTATTGCTGAGCAGCATTTAATGCACCT
GTGTGTGGAAGATGTGTCGAGGCTTTTGTCAGGGGATATTGAGCTTATGAACAGAAGACCTGCTTTTATAGAGTGGAGTC
AGAGGTATCAAAAGCCTACAAGAGATAAAGTAGTGATACCACAAGAATTAGAAGAAAAGCCCGATTTGAAAGAAAAGTTT
TTAAAAGTCTGGAACAACTCCTATGATGCTTATGAAAAACTTGTAGAAGTTTTGACGGAATATTTAGCTAGGGCAGAAGA
GAAAAAAGAGGGAGAAAGTGAAGAAAGATTTTACAATAGGATTAGTAAGATTGCCTTTGAAGATGCGAGATATGCCCTTC
TTTTAGCTACTAAGACAAGTTTTGCAGTGGCTTTAAATGCCCTAGATTTACAGGATATAGTGCGAAAACTTTTTGTACAT
CCTACTAAAGAGGCGAAGTTATTAGCTGAAAGAATAGTCGAACAAGGGGAAAAAATTGCACCGAGTATGTTAAGACATAC
AGCTCCTACTGTTTATCAATTAAAAGTTCACGATAGATTAAAGAATTTAGCGAGTGTTGTAAAAGAAGATGAGCTTTCAG
ATTCAAATGAGGATGTTATTTTAATAGATTATACAGGGAAAGATAGCGAATATTCTCCTGTAGATATTGTAATTATGCAT
ATTTTGTTTACATATTCAGGTAAAAATTTTGAAGCAGTGAGAAAAACAGTGAAGAATATGTCCGAAGAGGAGAAAAGTAA
AATCCTGCAGCAGGCAGTTGAAGATATAGGGGAGTTTGACCATTTAATAGAGGCATTTAAATCGATCAGATTTAAATTTC
AACTGAAGATAAGTGAAGCCAATTGGCATCAGCTTTTAAGACATAGAACTATTGTCTTTGATTACAGTGAACCGACAATT
GAAAATGGCTTTGTTATTCCTCCTAATATTGAAAAAGCGAATGCTTCTGAAATTTTAATAGAAGCAATAAAGGCTTCAGA
GGAATTATTTATAGAATTAAAAGAAAAATTGCCTGAAGTAAGTCCTTACGTGGTAACAAATGCACACAAACGCTTGGTTC
TTATGAATGCGGATTTATGGGCTTTTGATCATTTTGCAAATTTGAGATGCACTAATGAAGCTCAGTGGGATATACGGAAT
GTTTCTTTTAAGATGCTTGATTTGATTAAGGAAGTAGCTCCCCAGTTGACAACCTTTATGGCAAGGCGAAAAAAAGCTTA
A

Upstream 100 bases:

>100_bases
TACTTACCGATTTTATTTCCCTTTTTAAAAAAGGTTTTATGGTATAATAATATAAAGTGGAAAAAGTGATGATTTTACGA
TTTTGAAGGGAGTTTTTGAC

Downstream 100 bases:

>100_bases
AAGATGGAGATGAAATCATGAAAACCAGTTTTAAAGAAATAAGTTTGCCAAAGCTTAATAATTTGACACCATCACTGGAA
TCTACTGCCCTTAAATTAAT

Product: thymidylate synthase complementing protein ThyX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 506; Mature: 506

Protein sequence:

>506_residues
MKMRKLTLEEERLLENFVTDVYGPVYFIHSLPEFIIPPINSKVSRRDTSWRLNILESLTDGDLNITDYIPKHNIPLEKAI
QKAKEFHEKWVERFGHSSIAEQHLMHLCVEDVSRLLSGDIELMNRRPAFIEWSQRYQKPTRDKVVIPQELEEKPDLKEKF
LKVWNNSYDAYEKLVEVLTEYLARAEEKKEGESEERFYNRISKIAFEDARYALLLATKTSFAVALNALDLQDIVRKLFVH
PTKEAKLLAERIVEQGEKIAPSMLRHTAPTVYQLKVHDRLKNLASVVKEDELSDSNEDVILIDYTGKDSEYSPVDIVIMH
ILFTYSGKNFEAVRKTVKNMSEEEKSKILQQAVEDIGEFDHLIEAFKSIRFKFQLKISEANWHQLLRHRTIVFDYSEPTI
ENGFVIPPNIEKANASEILIEAIKASEELFIELKEKLPEVSPYVVTNAHKRLVLMNADLWAFDHFANLRCTNEAQWDIRN
VSFKMLDLIKEVAPQLTTFMARRKKA

Sequences:

>Translated_506_residues
MKMRKLTLEEERLLENFVTDVYGPVYFIHSLPEFIIPPINSKVSRRDTSWRLNILESLTDGDLNITDYIPKHNIPLEKAI
QKAKEFHEKWVERFGHSSIAEQHLMHLCVEDVSRLLSGDIELMNRRPAFIEWSQRYQKPTRDKVVIPQELEEKPDLKEKF
LKVWNNSYDAYEKLVEVLTEYLARAEEKKEGESEERFYNRISKIAFEDARYALLLATKTSFAVALNALDLQDIVRKLFVH
PTKEAKLLAERIVEQGEKIAPSMLRHTAPTVYQLKVHDRLKNLASVVKEDELSDSNEDVILIDYTGKDSEYSPVDIVIMH
ILFTYSGKNFEAVRKTVKNMSEEEKSKILQQAVEDIGEFDHLIEAFKSIRFKFQLKISEANWHQLLRHRTIVFDYSEPTI
ENGFVIPPNIEKANASEILIEAIKASEELFIELKEKLPEVSPYVVTNAHKRLVLMNADLWAFDHFANLRCTNEAQWDIRN
VSFKMLDLIKEVAPQLTTFMARRKKA
>Mature_506_residues
MKMRKLTLEEERLLENFVTDVYGPVYFIHSLPEFIIPPINSKVSRRDTSWRLNILESLTDGDLNITDYIPKHNIPLEKAI
QKAKEFHEKWVERFGHSSIAEQHLMHLCVEDVSRLLSGDIELMNRRPAFIEWSQRYQKPTRDKVVIPQELEEKPDLKEKF
LKVWNNSYDAYEKLVEVLTEYLARAEEKKEGESEERFYNRISKIAFEDARYALLLATKTSFAVALNALDLQDIVRKLFVH
PTKEAKLLAERIVEQGEKIAPSMLRHTAPTVYQLKVHDRLKNLASVVKEDELSDSNEDVILIDYTGKDSEYSPVDIVIMH
ILFTYSGKNFEAVRKTVKNMSEEEKSKILQQAVEDIGEFDHLIEAFKSIRFKFQLKISEANWHQLLRHRTIVFDYSEPTI
ENGFVIPPNIEKANASEILIEAIKASEELFIELKEKLPEVSPYVVTNAHKRLVLMNADLWAFDHFANLRCTNEAQWDIRN
VSFKMLDLIKEVAPQLTTFMARRKKA

Specific function: Unknown

COG id: COG1351

COG function: function code F; Predicted alternative thymidylate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 thyX (flavin-dependent thymidylate synthase) domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003669 [H]

Pfam domain/function: PF02511 Thy1 [H]

EC number: NA

Molecular weight: Translated: 59051; Mature: 59051

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMRKLTLEEERLLENFVTDVYGPVYFIHSLPEFIIPPINSKVSRRDTSWRLNILESLTD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCHHHCCCCHHHHHHHHHCCC
GDLNITDYIPKHNIPLEKAIQKAKEFHEKWVERFGHSSIAEQHLMHLCVEDVSRLLSGDI
CCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCH
ELMNRRPAFIEWSQRYQKPTRDKVVIPQELEEKPDLKEKFLKVWNNSYDAYEKLVEVLTE
HHHCCCCCEEEHHHHCCCCCCCCEECCHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHH
YLARAEEKKEGESEERFYNRISKIAFEDARYALLLATKTSFAVALNALDLQDIVRKLFVH
HHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHCC
PTKEAKLLAERIVEQGEKIAPSMLRHTAPTVYQLKVHDRLKNLASVVKEDELSDSNEDVI
CCHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCEE
LIDYTGKDSEYSPVDIVIMHILFTYSGKNFEAVRKTVKNMSEEEKSKILQQAVEDIGEFD
EEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
HLIEAFKSIRFKFQLKISEANWHQLLRHRTIVFDYSEPTIENGFVIPPNIEKANASEILI
HHHHHHHHCEEEEEEEECCCHHHHHHHCCEEEEECCCCCCCCCEEECCCCCCCCHHHHHH
EAIKASEELFIELKEKLPEVSPYVVTNAHKRLVLMNADLWAFDHFANLRCTNEAQWDIRN
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEECCHHHHHHHCCCEECCCCCCHHHH
VSFKMLDLIKEVAPQLTTFMARRKKA
HHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKMRKLTLEEERLLENFVTDVYGPVYFIHSLPEFIIPPINSKVSRRDTSWRLNILESLTD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCHHHCCCCHHHHHHHHHCCC
GDLNITDYIPKHNIPLEKAIQKAKEFHEKWVERFGHSSIAEQHLMHLCVEDVSRLLSGDI
CCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCH
ELMNRRPAFIEWSQRYQKPTRDKVVIPQELEEKPDLKEKFLKVWNNSYDAYEKLVEVLTE
HHHCCCCCEEEHHHHCCCCCCCCEECCHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHH
YLARAEEKKEGESEERFYNRISKIAFEDARYALLLATKTSFAVALNALDLQDIVRKLFVH
HHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHCC
PTKEAKLLAERIVEQGEKIAPSMLRHTAPTVYQLKVHDRLKNLASVVKEDELSDSNEDVI
CCHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCEE
LIDYTGKDSEYSPVDIVIMHILFTYSGKNFEAVRKTVKNMSEEEKSKILQQAVEDIGEFD
EEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
HLIEAFKSIRFKFQLKISEANWHQLLRHRTIVFDYSEPTIENGFVIPPNIEKANASEILI
HHHHHHHHCEEEEEEEECCCHHHHHHHCCEEEEECCCCCCCCCEEECCCCCCCCHHHHHH
EAIKASEELFIELKEKLPEVSPYVVTNAHKRLVLMNADLWAFDHFANLRCTNEAQWDIRN
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEECCHHHHHHHCCCEECCCCCCHHHH
VSFKMLDLIKEVAPQLTTFMARRKKA
HHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]