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The map label for this gene is fusA [H]

Identifier: 167039517

GI number: 167039517

Start: 901365

End: 903434

Strand: Direct

Name: fusA [H]

Synonym: Teth514_0864

Alternate gene names: 167039517

Gene position: 901365-903434 (Clockwise)

Preceding gene: 167039516

Following gene: 167039518

Centisome position: 36.68

GC content: 37.92

Gene sequence:

>2070_bases
ATGCCAAGAGACTACAGCTTAGATAAAGTTAGGAACATTGGTATTATGGCGCATATAGATGCAGGAAAAACCACTACTAC
CGAGCGAATACTTTTTTATACAGGGAAAGTTCATAAGTTAGGAGAAGTCCACGAAGGTACTGCTACAATGGACTGGATGG
TACAAGAGCAGGAAAGAGGTATAACTATAACTTCTGCGGCTACTACTTGTTATTGGAAAGGGCATAAAATAAACATTATC
GATACGCCGGGACACGTGGACTTTACTGTAGAAGTTGAAAGGTCTCTTAGAATATTAGACGGAGCTGTTGCGGTTTTTTC
TGCAAAAGAGGGTGTTGAGCCTCAATCTGAAACTGTGTGGAGACAGGCTGACAAATATCATGTTCCAAGAATTGCCTATG
TAAATAAAATGGATATAATAGGTGCTGACTTTTTCAATGTAATAAAAATGATAAAGGAAAGATTAGGAGCTAATCCTGTA
GCTATACAAATTCCTATTGGGAAAGAAGATACTTTCAGAGGCATTGTAGATTTAATTAAAATGGAAGCCATAATATATGA
AGATGATCTAGGTACTGTAATGGATGAGACTGAAATACCTGATGACTTAAAAGATTTAGCTGAGGAGTATAGAGAAAAAC
TATTAGAAGCAGTTTCTGAGCAAGATGAAACTATTTTAGAGAAGTATTTAGAAGGGGAAGAAATAACTGAAGAGGAGATT
CACAAAGCCTTAAGAAAAGGAACTATAAATGGTGAATTAGTACCAGTTGTCTGTGGTTCTTCCTATAAAAACAAAGGAAT
TCAGCCTATGTTGGATGCGATAGTAAGATATCTTCCTTCTCCACTCGACTTGCCACCTGTAAAAGGCATGGCATTAGCCA
CAGGAGAAGAGATAGAGAGAAAAGCCGACGATTCAGAGCCTTTTTCAGCATTAGCATTTAAAATTATGGCGGATCCTTAT
GTAGGTAAACTTGCTTTTTTTAGAGTATATTCAGGGACTCTAAATGCGGGCTCTTATGTATTAAATTCTACAAAAGGTAA
AAAAGAAAGAATAAGTAGAATTCTTCAAATGCATGCAAACCACAGGCAAGAAATGGAGGCTGTCTACACAGGCGATATAG
CTGCAGCTGTTGGACTAAAAGATACTACAACAGGAGATACCCTCTGTGATGAGAATCATCCAATACTTTTAGAATCAATG
GATTTTCCAGAACCAGTTATTTCTGTTGCTATAGAACCTAAGACTAAAGCTGCTCAAGAAAAAATGACTACAGCTTTATT
AAAACTAGCTGAGGAAGACCCAACCTTTAAGACATATACTGACCAAGAGACAGGACAGACAATAATAGCCGGTATGGGAG
AATTGCACTTAGAGATAATTGTTGATAGGCTAAGAAGAGAGTTTAATGTTGATTGCAATGTAGGTAAGCCTCAAGTTGCT
TACAAAGAGACTATTACTAAACCGGTTAAAATTGAAGGGAAATTTATTAGGCAATCCGGCGGACGCGGTCAGTATGGTCA
TGTTTGGTTGGAGATGGAACCTGCTCCAAGAGGAGAAGGCTATACATTTGAAAATCGCATTGTAGGAGGAGTTATTCCAA
AAGAATATATTCCTGCAGTTGACGCAGGTGTTCAAGAAGCTATGCAAAACGGTGTTCTTGGAGGATACCCTGTTATCGAT
GTAAAAGTGGCATTGGTAGATGGTTCTTACCATGAAGTTGACTCCTCAGATATGGCATTTAAAATAGCAGGTTCTATAGC
ATTTAAGGAAGGCATGAAAAAGGCAAACCCTGTTCTTTTGGAACCTATTATGAAAGTAGAGGTTGTGGTTCCAGAAGAAT
ACATGGGAGATATAATAGGAGATATAAATGCACGACGTGGAAGAGTTGAAGGAATGGAAGCAAGAGCTGGAGCCCAAGTT
ATAAGAGCATTTGTGCCGCTTGCTGAAATGTTTGGATATGCCACTGATTTAAGGTCAAAAACTCAAGGAAGAGGAACTTA
CACTATGCAGTTCCATCATTATGAAGAAGTTCCTAAAAATATTGCTGATCAAATATTAGAAAAGAAGTAA

Upstream 100 bases:

>100_bases
ACTCATAAAATGGCAGAAGCTAATAAAGCCTTTGCTCATTATAGATGGTAATTGTTTATAGGGGGTAGTGAATCTAGGGT
ACAAGAAAGGAGGATGGAAG

Downstream 100 bases:

>100_bases
AGGAGGAAAAGAGGATGGCGAAGCAAAAATTTGAGAGGAAGAAGCCGCACGTAAACGTAGGGACGATAGGTCACGTAGAC
CATGGTAAGACGACATTGAC

Product: elongation factor G

Products: GDP; phosphate

Alternate protein names: EF-G [H]

Number of amino acids: Translated: 689; Mature: 688

Protein sequence:

>689_residues
MPRDYSLDKVRNIGIMAHIDAGKTTTTERILFYTGKVHKLGEVHEGTATMDWMVQEQERGITITSAATTCYWKGHKINII
DTPGHVDFTVEVERSLRILDGAVAVFSAKEGVEPQSETVWRQADKYHVPRIAYVNKMDIIGADFFNVIKMIKERLGANPV
AIQIPIGKEDTFRGIVDLIKMEAIIYEDDLGTVMDETEIPDDLKDLAEEYREKLLEAVSEQDETILEKYLEGEEITEEEI
HKALRKGTINGELVPVVCGSSYKNKGIQPMLDAIVRYLPSPLDLPPVKGMALATGEEIERKADDSEPFSALAFKIMADPY
VGKLAFFRVYSGTLNAGSYVLNSTKGKKERISRILQMHANHRQEMEAVYTGDIAAAVGLKDTTTGDTLCDENHPILLESM
DFPEPVISVAIEPKTKAAQEKMTTALLKLAEEDPTFKTYTDQETGQTIIAGMGELHLEIIVDRLRREFNVDCNVGKPQVA
YKETITKPVKIEGKFIRQSGGRGQYGHVWLEMEPAPRGEGYTFENRIVGGVIPKEYIPAVDAGVQEAMQNGVLGGYPVID
VKVALVDGSYHEVDSSDMAFKIAGSIAFKEGMKKANPVLLEPIMKVEVVVPEEYMGDIIGDINARRGRVEGMEARAGAQV
IRAFVPLAEMFGYATDLRSKTQGRGTYTMQFHHYEEVPKNIADQILEKK

Sequences:

>Translated_689_residues
MPRDYSLDKVRNIGIMAHIDAGKTTTTERILFYTGKVHKLGEVHEGTATMDWMVQEQERGITITSAATTCYWKGHKINII
DTPGHVDFTVEVERSLRILDGAVAVFSAKEGVEPQSETVWRQADKYHVPRIAYVNKMDIIGADFFNVIKMIKERLGANPV
AIQIPIGKEDTFRGIVDLIKMEAIIYEDDLGTVMDETEIPDDLKDLAEEYREKLLEAVSEQDETILEKYLEGEEITEEEI
HKALRKGTINGELVPVVCGSSYKNKGIQPMLDAIVRYLPSPLDLPPVKGMALATGEEIERKADDSEPFSALAFKIMADPY
VGKLAFFRVYSGTLNAGSYVLNSTKGKKERISRILQMHANHRQEMEAVYTGDIAAAVGLKDTTTGDTLCDENHPILLESM
DFPEPVISVAIEPKTKAAQEKMTTALLKLAEEDPTFKTYTDQETGQTIIAGMGELHLEIIVDRLRREFNVDCNVGKPQVA
YKETITKPVKIEGKFIRQSGGRGQYGHVWLEMEPAPRGEGYTFENRIVGGVIPKEYIPAVDAGVQEAMQNGVLGGYPVID
VKVALVDGSYHEVDSSDMAFKIAGSIAFKEGMKKANPVLLEPIMKVEVVVPEEYMGDIIGDINARRGRVEGMEARAGAQV
IRAFVPLAEMFGYATDLRSKTQGRGTYTMQFHHYEEVPKNIADQILEKK
>Mature_688_residues
PRDYSLDKVRNIGIMAHIDAGKTTTTERILFYTGKVHKLGEVHEGTATMDWMVQEQERGITITSAATTCYWKGHKINIID
TPGHVDFTVEVERSLRILDGAVAVFSAKEGVEPQSETVWRQADKYHVPRIAYVNKMDIIGADFFNVIKMIKERLGANPVA
IQIPIGKEDTFRGIVDLIKMEAIIYEDDLGTVMDETEIPDDLKDLAEEYREKLLEAVSEQDETILEKYLEGEEITEEEIH
KALRKGTINGELVPVVCGSSYKNKGIQPMLDAIVRYLPSPLDLPPVKGMALATGEEIERKADDSEPFSALAFKIMADPYV
GKLAFFRVYSGTLNAGSYVLNSTKGKKERISRILQMHANHRQEMEAVYTGDIAAAVGLKDTTTGDTLCDENHPILLESMD
FPEPVISVAIEPKTKAAQEKMTTALLKLAEEDPTFKTYTDQETGQTIIAGMGELHLEIIVDRLRREFNVDCNVGKPQVAY
KETITKPVKIEGKFIRQSGGRGQYGHVWLEMEPAPRGEGYTFENRIVGGVIPKEYIPAVDAGVQEAMQNGVLGGYPVIDV
KVALVDGSYHEVDSSDMAFKIAGSIAFKEGMKKANPVLLEPIMKVEVVVPEEYMGDIIGDINARRGRVEGMEARAGAQVI
RAFVPLAEMFGYATDLRSKTQGRGTYTMQFHHYEEVPKNIADQILEKK

Specific function: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=697, Percent_Identity=42.8981348637016, Blast_Score=569, Evalue=1e-162,
Organism=Homo sapiens, GI19923640, Length=729, Percent_Identity=39.5061728395062, Blast_Score=497, Evalue=1e-140,
Organism=Homo sapiens, GI25306287, Length=705, Percent_Identity=37.4468085106383, Blast_Score=437, Evalue=1e-122,
Organism=Homo sapiens, GI25306283, Length=447, Percent_Identity=43.6241610738255, Blast_Score=340, Evalue=2e-93,
Organism=Homo sapiens, GI4503483, Length=488, Percent_Identity=27.0491803278689, Blast_Score=123, Evalue=5e-28,
Organism=Homo sapiens, GI157426893, Length=143, Percent_Identity=34.965034965035, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI94966754, Length=159, Percent_Identity=35.8490566037736, Blast_Score=94, Evalue=6e-19,
Organism=Homo sapiens, GI310132016, Length=119, Percent_Identity=38.655462184874, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI310110807, Length=119, Percent_Identity=38.655462184874, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI310123363, Length=119, Percent_Identity=38.655462184874, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI217272892, Length=135, Percent_Identity=32.5925925925926, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI217272894, Length=135, Percent_Identity=32.5925925925926, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1789738, Length=703, Percent_Identity=62.1621621621622, Blast_Score=895, Evalue=0.0,
Organism=Escherichia coli, GI1790835, Length=472, Percent_Identity=28.1779661016949, Blast_Score=165, Evalue=8e-42,
Organism=Escherichia coli, GI48994988, Length=136, Percent_Identity=41.1764705882353, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI1788922, Length=155, Percent_Identity=36.7741935483871, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17533571, Length=679, Percent_Identity=41.6789396170839, Blast_Score=540, Evalue=1e-153,
Organism=Caenorhabditis elegans, GI17556745, Length=722, Percent_Identity=29.3628808864266, Blast_Score=328, Evalue=4e-90,
Organism=Caenorhabditis elegans, GI17506493, Length=832, Percent_Identity=26.3221153846154, Blast_Score=179, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17557151, Length=157, Percent_Identity=37.5796178343949, Blast_Score=109, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI71988819, Length=131, Percent_Identity=32.0610687022901, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71988811, Length=131, Percent_Identity=32.0610687022901, Blast_Score=73, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6323098, Length=688, Percent_Identity=42.296511627907, Blast_Score=565, Evalue=1e-162,
Organism=Saccharomyces cerevisiae, GI6322359, Length=786, Percent_Identity=32.0610687022901, Blast_Score=374, Evalue=1e-104,
Organism=Saccharomyces cerevisiae, GI6324707, Length=487, Percent_Identity=27.5154004106776, Blast_Score=122, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6320593, Length=487, Percent_Identity=27.5154004106776, Blast_Score=122, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6323320, Length=158, Percent_Identity=31.6455696202532, Blast_Score=84, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6324166, Length=143, Percent_Identity=34.965034965035, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24582462, Length=693, Percent_Identity=41.991341991342, Blast_Score=569, Evalue=1e-162,
Organism=Drosophila melanogaster, GI221458488, Length=726, Percent_Identity=33.7465564738292, Blast_Score=387, Evalue=1e-107,
Organism=Drosophila melanogaster, GI24585709, Length=824, Percent_Identity=26.0922330097087, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24585711, Length=823, Percent_Identity=26.0024301336573, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24585713, Length=823, Percent_Identity=26.0024301336573, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI78706572, Length=158, Percent_Identity=36.7088607594937, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI28574573, Length=139, Percent_Identity=35.9712230215827, Blast_Score=86, Evalue=9e-17,
Organism=Drosophila melanogaster, GI21357743, Length=134, Percent_Identity=31.3432835820896, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR004540
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: 3.6.5.3

Molecular weight: Translated: 76674; Mature: 76543

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRDYSLDKVRNIGIMAHIDAGKTTTTERILFYTGKVHKLGEVHEGTATMDWMVQEQERG
CCCCCCHHHHHCCCEEEEECCCCCCCCCEEEEEECCCHHCCCCCCCCCHHHHHEEHHHCC
ITITSAATTCYWKGHKINIIDTPGHVDFTVEVERSLRILDGAVAVFSAKEGVEPQSETVW
EEEEECCEEEEECCCEEEEEECCCCEEEEEEECCCHHHHHHHHHEEECCCCCCCCHHHHH
RQADKYHVPRIAYVNKMDIIGADFFNVIKMIKERLGANPVAIQIPIGKEDTFRGIVDLIK
HHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHH
MEAIIYEDDLGTVMDETEIPDDLKDLAEEYREKLLEAVSEQDETILEKYLEGEEITEEEI
HHHEEEECCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHH
HKALRKGTINGELVPVVCGSSYKNKGIQPMLDAIVRYLPSPLDLPPVKGMALATGEEIER
HHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHH
KADDSEPFSALAFKIMADPYVGKLAFFRVYSGTLNAGSYVLNSTKGKKERISRILQMHAN
HCCCCCCHHHHHHHHHCCCCHHHEEEEEEECCCCCCCCEEEECCCCHHHHHHHHHHHHHC
HRQEMEAVYTGDIAAAVGLKDTTTGDTLCDENHPILLESMDFPEPVISVAIEPKTKAAQE
HHHHHHHHHCCCHHEEECCCCCCCCCCCCCCCCCEEEECCCCCCCCEEEEECCCHHHHHH
KMTTALLKLAEEDPTFKTYTDQETGQTIIAGMGELHLEIIVDRLRREFNVDCNVGKPQVA
HHHHHHHHHHCCCCCCEEECCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCHH
YKETITKPVKIEGKFIRQSGGRGQYGHVWLEMEPAPRGEGYTFENRIVGGVIPKEYIPAV
HHHHCCCCEEECCEEEECCCCCCCCCEEEEEECCCCCCCCEEECCCEECCCCCHHHCCHH
DAGVQEAMQNGVLGGYPVIDVKVALVDGSYHEVDSSDMAFKIAGSIAFKEGMKKANPVLL
HHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCCCCCEEEEECHHHHHHHHHHCCCCEE
EPIMKVEVVVPEEYMGDIIGDINARRGRVEGMEARAGAQVIRAFVPLAEMFGYATDLRSK
CCCEEEEEEECHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQGRGTYTMQFHHYEEVPKNIADQILEKK
CCCCCEEEEEECCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PRDYSLDKVRNIGIMAHIDAGKTTTTERILFYTGKVHKLGEVHEGTATMDWMVQEQERG
CCCCCHHHHHCCCEEEEECCCCCCCCCEEEEEECCCHHCCCCCCCCCHHHHHEEHHHCC
ITITSAATTCYWKGHKINIIDTPGHVDFTVEVERSLRILDGAVAVFSAKEGVEPQSETVW
EEEEECCEEEEECCCEEEEEECCCCEEEEEEECCCHHHHHHHHHEEECCCCCCCCHHHHH
RQADKYHVPRIAYVNKMDIIGADFFNVIKMIKERLGANPVAIQIPIGKEDTFRGIVDLIK
HHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHH
MEAIIYEDDLGTVMDETEIPDDLKDLAEEYREKLLEAVSEQDETILEKYLEGEEITEEEI
HHHEEEECCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHH
HKALRKGTINGELVPVVCGSSYKNKGIQPMLDAIVRYLPSPLDLPPVKGMALATGEEIER
HHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHH
KADDSEPFSALAFKIMADPYVGKLAFFRVYSGTLNAGSYVLNSTKGKKERISRILQMHAN
HCCCCCCHHHHHHHHHCCCCHHHEEEEEEECCCCCCCCEEEECCCCHHHHHHHHHHHHHC
HRQEMEAVYTGDIAAAVGLKDTTTGDTLCDENHPILLESMDFPEPVISVAIEPKTKAAQE
HHHHHHHHHCCCHHEEECCCCCCCCCCCCCCCCCEEEECCCCCCCCEEEEECCCHHHHHH
KMTTALLKLAEEDPTFKTYTDQETGQTIIAGMGELHLEIIVDRLRREFNVDCNVGKPQVA
HHHHHHHHHHCCCCCCEEECCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCHH
YKETITKPVKIEGKFIRQSGGRGQYGHVWLEMEPAPRGEGYTFENRIVGGVIPKEYIPAV
HHHHCCCCEEECCEEEECCCCCCCCCEEEEEECCCCCCCCEEECCCEECCCCCHHHCCHH
DAGVQEAMQNGVLGGYPVIDVKVALVDGSYHEVDSSDMAFKIAGSIAFKEGMKKANPVLL
HHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCCCCCEEEEECHHHHHHHHHHCCCCEE
EPIMKVEVVVPEEYMGDIIGDINARRGRVEGMEARAGAQVIRAFVPLAEMFGYATDLRSK
CCCEEEEEEECHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQGRGTYTMQFHHYEEVPKNIADQILEKK
CCCCCEEEEEECCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP; H2O

Specific reaction: GTP + H2O = GDP + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]