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The map label for this gene is sigH [H]

Identifier: 167039504

GI number: 167039504

Start: 886863

End: 887507

Strand: Direct

Name: sigH [H]

Synonym: Teth514_0850

Alternate gene names: 167039504

Gene position: 886863-887507 (Clockwise)

Preceding gene: 167039503

Following gene: 167039505

Centisome position: 36.09

GC content: 37.21

Gene sequence:

>645_bases
GTGAAATCTGGGGCGCAGCAGGATTACTATCAACCATATGACCAAATGGAAGAGGAGGAGGTCGTTTTTAGAGCTCAAAA
AGGAGACGAAATTGCTTTAGAGTACCTTATTGAAAGGTATAAAAGTTTTGTAAAAGCAAAAGCTCGCGCTTATTTTTTAG
TAGGTGCCGATAAGGAAGATATTATTCAAGAAGGGATGATAGGCCTTTATAAAGCAATTCGAGATTACAAAAGTGACAAG
CTCACCTCTTTCAAAGCTTTTGCGGAATTATGTGTGACTCGTCAAATTATTACTGCTATTAAAACCGCAACAAGGCAGAA
GCACATACCCCTTAATTCTTATGTTTCCCTCAATAAGCCCATCTTTGATGAAGAATCTGATAGGACTCTTATGGACGTTG
TTTCTACCCAATGCATTGCTGACCCTGAAGAGTTAATAATAAGCAAAGAGGAATACGTTAACATTGAGAGCAAGATGGAA
GAATTGTTGAGTGGGTTAGAGTGGGAGGTCTTGGTATCATATTTAGATGGTAAGTCATATCAAGAAATTGCTGAAGATTT
AAATAGGCATGTTAAATCCGTAGACAATGCTCTACAACGGGTAAAAAGAAAATTAGAAAGATATCTTGAAATGAGAAACA
GCTAA

Upstream 100 bases:

>100_bases
AAATGGCAGAAAACAGTTAAAATTAGCTTGACTACCTTTACCAATATAATGTATAATTATAACGTATAAAGTTGCCGGAA
TAATAAATGGGGGCGGTATT

Downstream 100 bases:

>100_bases
CTATTGACATTTAGAAAACTTTATAGTAAAATCAAAAATCGGAGTCGTGATATTCCCTTTTGCCCACGTAGCTCAGTAGG
TAGAGCGTCGCCTTGGTAAG

Product: RNA polymerase factor sigma-70

Products: NA

Alternate protein names: Sigma-30 [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MKSGAQQDYYQPYDQMEEEEVVFRAQKGDEIALEYLIERYKSFVKAKARAYFLVGADKEDIIQEGMIGLYKAIRDYKSDK
LTSFKAFAELCVTRQIITAIKTATRQKHIPLNSYVSLNKPIFDEESDRTLMDVVSTQCIADPEELIISKEEYVNIESKME
ELLSGLEWEVLVSYLDGKSYQEIAEDLNRHVKSVDNALQRVKRKLERYLEMRNS

Sequences:

>Translated_214_residues
MKSGAQQDYYQPYDQMEEEEVVFRAQKGDEIALEYLIERYKSFVKAKARAYFLVGADKEDIIQEGMIGLYKAIRDYKSDK
LTSFKAFAELCVTRQIITAIKTATRQKHIPLNSYVSLNKPIFDEESDRTLMDVVSTQCIADPEELIISKEEYVNIESKME
ELLSGLEWEVLVSYLDGKSYQEIAEDLNRHVKSVDNALQRVKRKLERYLEMRNS
>Mature_214_residues
MKSGAQQDYYQPYDQMEEEEVVFRAQKGDEIALEYLIERYKSFVKAKARAYFLVGADKEDIIQEGMIGLYKAIRDYKSDK
LTSFKAFAELCVTRQIITAIKTATRQKHIPLNSYVSLNKPIFDEESDRTLMDVVSTQCIADPEELIISKEEYVNIESKME
ELLSGLEWEVLVSYLDGKSYQEIAEDLNRHVKSVDNALQRVKRKLERYLEMRNS

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in the transition to post-exponential phase in the beginning of sporulation [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family [H]

Homologues:

None

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014218
- InterPro:   IPR016371
- InterPro:   IPR000943
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 24936; Mature: 24936

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00622 HTH_LUXR_1 ; PS00715 SIGMA70_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSGAQQDYYQPYDQMEEEEVVFRAQKGDEIALEYLIERYKSFVKAKARAYFLVGADKED
CCCCCCCHHCCCHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCHHH
IIQEGMIGLYKAIRDYKSDKLTSFKAFAELCVTRQIITAIKTATRQKHIPLNSYVSLNKP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCC
IFDEESDRTLMDVVSTQCIADPEELIISKEEYVNIESKMEELLSGLEWEVLVSYLDGKSY
CCCCCCCHHHHHHHHHHHCCCHHHHHHCHHHHCCHHHHHHHHHHCCHHHHHHHHHCCCCH
QEIAEDLNRHVKSVDNALQRVKRKLERYLEMRNS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKSGAQQDYYQPYDQMEEEEVVFRAQKGDEIALEYLIERYKSFVKAKARAYFLVGADKED
CCCCCCCHHCCCHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCHHH
IIQEGMIGLYKAIRDYKSDKLTSFKAFAELCVTRQIITAIKTATRQKHIPLNSYVSLNKP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCC
IFDEESDRTLMDVVSTQCIADPEELIISKEEYVNIESKMEELLSGLEWEVLVSYLDGKSY
CCCCCCCHHHHHHHHHHHCCCHHHHHHCHHHHCCHHHHHHHHHHCCHHHHHHHHHCCCCH
QEIAEDLNRHVKSVDNALQRVKRKLERYLEMRNS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3277943; 6322121 [H]