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The map label for this gene is yqjD [H]

Identifier: 167039451

GI number: 167039451

Start: 831349

End: 832899

Strand: Direct

Name: yqjD [H]

Synonym: Teth514_0797

Alternate gene names: 167039451

Gene position: 831349-832899 (Clockwise)

Preceding gene: 167039450

Following gene: 167039452

Centisome position: 33.83

GC content: 40.04

Gene sequence:

>1551_bases
ATGAGTGTTCATGATATGATAGAAGAGCTAAAAAGAAGAAGAGAAAAAGTTTTAGAAGGTGGAGGGGCTAAAAGAATAGC
TGCTCAGCACGAAAAGGGTAAATTGACTGCAAGGGAAAGGATACATAAGCTTCTTGACAAGGACAGTTTTGTAGAAATAG
ACCCTTTTGTAGAGCATCGGTGTTATGACTTTGGGATGGAAAAGCAAAAATATCCTGGAGAAGGAGTTGTAACAGGCTAC
GGAACAATAGATGGAAGATTAGTCTATGTATATGCGCAGGATTTTACTGTGTTAGGTGGGTCATTAGGAGAGTACCATGC
GAAAAAGATAACAAAAGTTATGGATATGGCGATGAAAATGGGAGCGCCTATAATAGGGCTTAACGATTCGGGGGGTGCTC
GCATACAGGAAGGGGTGGATGCTCTTTCTGGGTATGGAAACATATTTTACAGGAATACTTTGGCCTCCGGCGTCATACCG
CAAATATCGGTAATAATGGGGCCGAGCGCTGGGGGAGCCGTGTATTCACCGGCATTGACAGATTTTATTTTTATGGTAGA
CAAAACTAGTCAAATGTTTATAACAGGTCCACAAGTTATAAAAGCTGTAACTGGAGAAGAAGTTACTCCTGAAGAATTGG
GAGGATCAATAACTCACAATAGATTAAGCGGTGTTGCTCATTTTAGGGGTCCAAATGATGAAGAAGTTCTTAAGATGGTG
AGGAATTTATTGAGTTATTTACCTTCTAACAACTTAGAAGACCCACCACAATACGAGACAGGGGATAATCCCAATAGAGT
TTCTCAAAGACTTATGGAGATAATTCCAGACAATCCTAATAAGCCTTATGACATGAAAGAATTAATAAGAGAAATAGTCG
ACAATGGAGAATTTTTAGAGTCACAAGAGATGTACGCAGAAAATATCATCACAGCTTTTGCAAGACTTAATGGAAAGACA
ATAGGAATTGTTGCAAATCAGCCAAGAGTATTAGCAGGAGTACTTGACATAAATGCTTCTGACAAAGTGGCCAGGTTTAT
TCGCTTTTGTGATGCTTTTAATATACCTATACTTAGCATAGTGGATGTGCCTGGATTTTTGCCAGGGACAAATCAAGAAT
ATGGTGGGATAATAAGACATGGGGCAAAAATGCTTTACGCTTATTCTGAGGCTACTGTTCCTAAGGTTACTTTGATTGTA
AGGAAGGCTTACGGTGGGGCTTATCTTGCTATGTGCAGCAAAGACTTAGGGGCTGACATGGTGTTTGCATGGCCTACGGC
AGAGATTGCGGTTATGGGACCAGAAGGAGCAGCTAACATAGTTTTTAAAAATGAAATCAATGAGGCAGAAAATCCTGCAG
AAGTGAGGCAGCAAAAGATAAATGAATACAGAGATAATTTTGCAAATCCATACAGAGCTGCAGCTCGTGGCTATGTAGAT
GATGTAATTCTTCCTTCTGAGACAAGGCCAAGACTCATATCAGCTTTTGATATGTTATCTAGCAAAAGAGAGAGTCGTCC
TCCTAAGAAACATGGCAATATACCTCTGTAA

Upstream 100 bases:

>100_bases
TTATTGTGTATTTGGGAAGTATGTGGTATATTATTTTAGTAGGTACTAATAATAACTGCTACTATTCGGTCGCAGTGAGG
CTGTAAGGAGGTATAATTGT

Downstream 100 bases:

>100_bases
GGTGGTGCTTTTATGGAAGGGTTTTTGGAGTTTTTGAAGAAAATCTTTAATAATAAAGAGGAAGAGAAAGTAAAGAAGGA
AGAAAAAATAGATAAAAATG

Product: carboxyl transferase

Products: NA

Alternate protein names: PCCase; Propanoyl-CoA:carbon dioxide ligase [H]

Number of amino acids: Translated: 516; Mature: 515

Protein sequence:

>516_residues
MSVHDMIEELKRRREKVLEGGGAKRIAAQHEKGKLTARERIHKLLDKDSFVEIDPFVEHRCYDFGMEKQKYPGEGVVTGY
GTIDGRLVYVYAQDFTVLGGSLGEYHAKKITKVMDMAMKMGAPIIGLNDSGGARIQEGVDALSGYGNIFYRNTLASGVIP
QISVIMGPSAGGAVYSPALTDFIFMVDKTSQMFITGPQVIKAVTGEEVTPEELGGSITHNRLSGVAHFRGPNDEEVLKMV
RNLLSYLPSNNLEDPPQYETGDNPNRVSQRLMEIIPDNPNKPYDMKELIREIVDNGEFLESQEMYAENIITAFARLNGKT
IGIVANQPRVLAGVLDINASDKVARFIRFCDAFNIPILSIVDVPGFLPGTNQEYGGIIRHGAKMLYAYSEATVPKVTLIV
RKAYGGAYLAMCSKDLGADMVFAWPTAEIAVMGPEGAANIVFKNEINEAENPAEVRQQKINEYRDNFANPYRAAARGYVD
DVILPSETRPRLISAFDMLSSKRESRPPKKHGNIPL

Sequences:

>Translated_516_residues
MSVHDMIEELKRRREKVLEGGGAKRIAAQHEKGKLTARERIHKLLDKDSFVEIDPFVEHRCYDFGMEKQKYPGEGVVTGY
GTIDGRLVYVYAQDFTVLGGSLGEYHAKKITKVMDMAMKMGAPIIGLNDSGGARIQEGVDALSGYGNIFYRNTLASGVIP
QISVIMGPSAGGAVYSPALTDFIFMVDKTSQMFITGPQVIKAVTGEEVTPEELGGSITHNRLSGVAHFRGPNDEEVLKMV
RNLLSYLPSNNLEDPPQYETGDNPNRVSQRLMEIIPDNPNKPYDMKELIREIVDNGEFLESQEMYAENIITAFARLNGKT
IGIVANQPRVLAGVLDINASDKVARFIRFCDAFNIPILSIVDVPGFLPGTNQEYGGIIRHGAKMLYAYSEATVPKVTLIV
RKAYGGAYLAMCSKDLGADMVFAWPTAEIAVMGPEGAANIVFKNEINEAENPAEVRQQKINEYRDNFANPYRAAARGYVD
DVILPSETRPRLISAFDMLSSKRESRPPKKHGNIPL
>Mature_515_residues
SVHDMIEELKRRREKVLEGGGAKRIAAQHEKGKLTARERIHKLLDKDSFVEIDPFVEHRCYDFGMEKQKYPGEGVVTGYG
TIDGRLVYVYAQDFTVLGGSLGEYHAKKITKVMDMAMKMGAPIIGLNDSGGARIQEGVDALSGYGNIFYRNTLASGVIPQ
ISVIMGPSAGGAVYSPALTDFIFMVDKTSQMFITGPQVIKAVTGEEVTPEELGGSITHNRLSGVAHFRGPNDEEVLKMVR
NLLSYLPSNNLEDPPQYETGDNPNRVSQRLMEIIPDNPNKPYDMKELIREIVDNGEFLESQEMYAENIITAFARLNGKTI
GIVANQPRVLAGVLDINASDKVARFIRFCDAFNIPILSIVDVPGFLPGTNQEYGGIIRHGAKMLYAYSEATVPKVTLIVR
KAYGGAYLAMCSKDLGADMVFAWPTAEIAVMGPEGAANIVFKNEINEAENPAEVRQQKINEYRDNFANPYRAAARGYVDD
VILPSETRPRLISAFDMLSSKRESRPPKKHGNIPL

Specific function: This Protein Is A Component Of The Acetyl Coenzyme A Carboxylase Complex; First, Biotin Carboxylase Catalyzes The Carboxylation Of The Carrier Protein And Then The Transcarboxylase Transfers The Carboxyl Group To Form Malonyl-CoA. [C]

COG id: COG4799

COG function: function code I; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI119943100, Length=511, Percent_Identity=60.2739726027397, Blast_Score=624, Evalue=1e-179,
Organism=Homo sapiens, GI295821216, Length=531, Percent_Identity=58.0037664783427, Blast_Score=612, Evalue=1e-175,
Organism=Homo sapiens, GI11545863, Length=505, Percent_Identity=33.6633663366337, Blast_Score=256, Evalue=4e-68,
Organism=Homo sapiens, GI134142062, Length=401, Percent_Identity=24.9376558603491, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI38679974, Length=394, Percent_Identity=24.1116751269036, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI38679971, Length=394, Percent_Identity=24.1116751269036, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI38679977, Length=394, Percent_Identity=24.1116751269036, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI38679967, Length=394, Percent_Identity=24.1116751269036, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI38679960, Length=394, Percent_Identity=24.1116751269036, Blast_Score=73, Evalue=6e-13,
Organism=Escherichia coli, GI1788655, Length=190, Percent_Identity=29.4736842105263, Blast_Score=76, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI25147362, Length=509, Percent_Identity=58.5461689587426, Blast_Score=617, Evalue=1e-177,
Organism=Caenorhabditis elegans, GI25147359, Length=509, Percent_Identity=58.5461689587426, Blast_Score=615, Evalue=1e-176,
Organism=Caenorhabditis elegans, GI17552936, Length=521, Percent_Identity=34.7408829174664, Blast_Score=293, Evalue=2e-79,
Organism=Caenorhabditis elegans, GI71997163, Length=310, Percent_Identity=26.4516129032258, Blast_Score=75, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6324343, Length=347, Percent_Identity=23.342939481268, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24586065, Length=519, Percent_Identity=34.6820809248555, Blast_Score=274, Evalue=1e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.3 [H]

Molecular weight: Translated: 56975; Mature: 56844

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVHDMIEELKRRREKVLEGGGAKRIAAQHEKGKLTARERIHKLLDKDSFVEIDPFVEHR
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHCCCCCEEECHHHHHH
CYDFGMEKQKYPGEGVVTGYGTIDGRLVYVYAQDFTVLGGSLGEYHAKKITKVMDMAMKM
HHHCCCCCCCCCCCCEEEEECCCCCEEEEEEECCEEEECCCHHHHHHHHHHHHHHHHHHH
GAPIIGLNDSGGARIQEGVDALSGYGNIFYRNTLASGVIPQISVIMGPSAGGAVYSPALT
CCCEEEECCCCCCHHHHHHHHHHCCCCEEEHHHHHHCCCCEEEEEECCCCCCCEECHHHH
DFIFMVDKTSQMFITGPQVIKAVTGEEVTPEELGGSITHNRLSGVAHFRGPNDEEVLKMV
HHHHEEECCCCEEEECHHHHHHHCCCCCCHHHHCCCCHHHHHHCHHCCCCCCHHHHHHHH
RNLLSYLPSNNLEDPPQYETGDNPNRVSQRLMEIIPDNPNKPYDMKELIREIVDNGEFLE
HHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHH
SQEMYAENIITAFARLNGKTIGIVANQPRVLAGVLDINASDKVARFIRFCDAFNIPILSI
HHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEE
VDVPGFLPGTNQEYGGIIRHGAKMLYAYSEATVPKVTLIVRKAYGGAYLAMCSKDLGADM
ECCCCCCCCCCCHHHHHHHHCHHHEEEECCCCCCEEEEEEEHHCCCEEEEHHHHCCCCCE
VFAWPTAEIAVMGPEGAANIVFKNEINEAENPAEVRQQKINEYRDNFANPYRAAARGYVD
EEECCCCEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCHH
DVILPSETRPRLISAFDMLSSKRESRPPKKHGNIPL
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SVHDMIEELKRRREKVLEGGGAKRIAAQHEKGKLTARERIHKLLDKDSFVEIDPFVEHR
CHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHCCCCCEEECHHHHHH
CYDFGMEKQKYPGEGVVTGYGTIDGRLVYVYAQDFTVLGGSLGEYHAKKITKVMDMAMKM
HHHCCCCCCCCCCCCEEEEECCCCCEEEEEEECCEEEECCCHHHHHHHHHHHHHHHHHHH
GAPIIGLNDSGGARIQEGVDALSGYGNIFYRNTLASGVIPQISVIMGPSAGGAVYSPALT
CCCEEEECCCCCCHHHHHHHHHHCCCCEEEHHHHHHCCCCEEEEEECCCCCCCEECHHHH
DFIFMVDKTSQMFITGPQVIKAVTGEEVTPEELGGSITHNRLSGVAHFRGPNDEEVLKMV
HHHHEEECCCCEEEECHHHHHHHCCCCCCHHHHCCCCHHHHHHCHHCCCCCCHHHHHHHH
RNLLSYLPSNNLEDPPQYETGDNPNRVSQRLMEIIPDNPNKPYDMKELIREIVDNGEFLE
HHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHH
SQEMYAENIITAFARLNGKTIGIVANQPRVLAGVLDINASDKVARFIRFCDAFNIPILSI
HHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEE
VDVPGFLPGTNQEYGGIIRHGAKMLYAYSEATVPKVTLIVRKAYGGAYLAMCSKDLGADM
ECCCCCCCCCCCHHHHHHHHCHHHEEEECCCCCCEEEEEEEHHCCCEEEEHHHHCCCCCE
VFAWPTAEIAVMGPEGAANIVFKNEINEAENPAEVRQQKINEYRDNFANPYRAAARGYVD
EEECCCCEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCHH
DVILPSETRPRLISAFDMLSSKRESRPPKKHGNIPL
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]