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The map label for this gene is aroB [H]

Identifier: 167039355

GI number: 167039355

Start: 728634

End: 729539

Strand: Direct

Name: aroB [H]

Synonym: Teth514_0697

Alternate gene names: 167039355

Gene position: 728634-729539 (Clockwise)

Preceding gene: 167039354

Following gene: 167039361

Centisome position: 29.65

GC content: 34.22

Gene sequence:

>906_bases
ATGAGAATTTGTGCGATTGATATAGGGACAAATTCAATACGCCAACTTATATGTGACATAGATAATGAAAATATAAACAA
GATACAAAAAGACGTTGAAATAACTCGATTAGGGGAAGGAATTTCTAAAACGGGGAAGTTAAATAATAATGCGATACAGA
GAAGCATTGAAGTGATTGAACGCTTTGTGAAATTGGCCCAAGAAAAAGGCGCAGAAGTTATATATGCTTTTGCAACATCT
GCGATGAGGGATGCTAAAAATAAAGATGCTTTTTTTGAGCAAATTGGAAAACTTGGGCTAGAGGTAGAAATCATAGATGG
AGAAACAGAGAGCTTGTTTGGATATATGGGAGCGGTGATGGGGGTTAATAAGGAAAATGCACTGGTGTTAGATATAGGAG
GAGGAAGTACTGAATTAGCATATAAAGGTAGAGAATTTGTAAAAGAAAGTTTCGATATTGGGGCTGTGAGGCTTACTGAA
AAATTTATTAAAAATGACCCTCCTACAGCTGAGGAATATGATGAAATCAGGTTGCATATAATAGATACAATGGTAAATTC
CATTAATAAGTACAAAGAAGTTGAAAATGTCATCGGCATAGGAGGAACAATAACAACTCTTGCTGCTGTTTCTCAGCAAT
TAGAAATTTATTCTCAAGAAAAAGTTCATGGCTATCAGCTAAAAAAAGAAGAAATTAAGAGGATTTTAGATAAATTTATG
TCTGTTACATTGGAAGAGCGGAAAAAATTTTTTGGATTGCAACCACAAAGGGCTGATATAATAATTGCGGGAACTGCTAT
ATTACTGACCATATTAGAAATGCTGAGTTTCAAAGAAATAACCGTTAGTGAGTGGGATAATTTAGAAGGAGCAGTCCTAT
ATAAATTTCGGGAATTTAAGTTATGA

Upstream 100 bases:

>100_bases
AGAAAAAGCAATGGATATTAACTTCGGGTTATGCCCGAAGATTTTTCATAAGCGAAGGAGAAATTTTACAGGTTTTTACC
TGTGATAGTTGGGGGTTATT

Downstream 100 bases:

>100_bases
AAATGGAATTTTCATTTGAAGTTGCAAAAGTGGATAAAAAAACTATTGACTTAGAGATATAGATATAATATAATAAATAC
TGTCTCAAGGAGATGAAGCC

Product: Ppx/GppA phosphatase

Products: NA

Alternate protein names: 3-dehydroquinate synthase; Unknown phosphatase [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MRICAIDIGTNSIRQLICDIDNENINKIQKDVEITRLGEGISKTGKLNNNAIQRSIEVIERFVKLAQEKGAEVIYAFATS
AMRDAKNKDAFFEQIGKLGLEVEIIDGETESLFGYMGAVMGVNKENALVLDIGGGSTELAYKGREFVKESFDIGAVRLTE
KFIKNDPPTAEEYDEIRLHIIDTMVNSINKYKEVENVIGIGGTITTLAAVSQQLEIYSQEKVHGYQLKKEEIKRILDKFM
SVTLEERKKFFGLQPQRADIIIAGTAILLTILEMLSFKEITVSEWDNLEGAVLYKFREFKL

Sequences:

>Translated_301_residues
MRICAIDIGTNSIRQLICDIDNENINKIQKDVEITRLGEGISKTGKLNNNAIQRSIEVIERFVKLAQEKGAEVIYAFATS
AMRDAKNKDAFFEQIGKLGLEVEIIDGETESLFGYMGAVMGVNKENALVLDIGGGSTELAYKGREFVKESFDIGAVRLTE
KFIKNDPPTAEEYDEIRLHIIDTMVNSINKYKEVENVIGIGGTITTLAAVSQQLEIYSQEKVHGYQLKKEEIKRILDKFM
SVTLEERKKFFGLQPQRADIIIAGTAILLTILEMLSFKEITVSEWDNLEGAVLYKFREFKL
>Mature_301_residues
MRICAIDIGTNSIRQLICDIDNENINKIQKDVEITRLGEGISKTGKLNNNAIQRSIEVIERFVKLAQEKGAEVIYAFATS
AMRDAKNKDAFFEQIGKLGLEVEIIDGETESLFGYMGAVMGVNKENALVLDIGGGSTELAYKGREFVKESFDIGAVRLTE
KFIKNDPPTAEEYDEIRLHIIDTMVNSINKYKEVENVIGIGGTITTLAAVSQQLEIYSQEKVHGYQLKKEEIKRILDKFM
SVTLEERKKFFGLQPQRADIIIAGTAILLTILEMLSFKEITVSEWDNLEGAVLYKFREFKL

Specific function: Degradation Of Inorganic Polyphosphates. Orthophosphate Is Released Progressively From The Ends Of Polyphosphate Of Circa 500 Residues Long, While Chains Of Circa 15 Residues Compete Poorly With Polyphosphate As Substrate. [C]

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI1788848, Length=307, Percent_Identity=24.1042345276873, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI48994966, Length=301, Percent_Identity=24.5847176079734, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002658
- InterPro:   IPR016037
- InterPro:   IPR003695 [H]

Pfam domain/function: PF01761 DHQ_synthase; PF02541 Ppx-GppA [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 33903; Mature: 33903

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRICAIDIGTNSIRQLICDIDNENINKIQKDVEITRLGEGISKTGKLNNNAIQRSIEVIE
CEEEEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHH
RFVKLAQEKGAEVIYAFATSAMRDAKNKDAFFEQIGKLGLEVEIIDGETESLFGYMGAVM
HHHHHHHHCCCCEEHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHH
GVNKENALVLDIGGGSTELAYKGREFVKESFDIGAVRLTEKFIKNDPPTAEEYDEIRLHI
CCCCCCEEEEEECCCCCHHHHCCHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHH
IDTMVNSINKYKEVENVIGIGGTITTLAAVSQQLEIYSQEKVHGYQLKKEEIKRILDKFM
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
SVTLEERKKFFGLQPQRADIIIAGTAILLTILEMLSFKEITVSEWDNLEGAVLYKFREFK
HHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHCCCCCCHHCCCCCCCEEEEEEECCC
L
C
>Mature Secondary Structure
MRICAIDIGTNSIRQLICDIDNENINKIQKDVEITRLGEGISKTGKLNNNAIQRSIEVIE
CEEEEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHH
RFVKLAQEKGAEVIYAFATSAMRDAKNKDAFFEQIGKLGLEVEIIDGETESLFGYMGAVM
HHHHHHHHCCCCEEHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHH
GVNKENALVLDIGGGSTELAYKGREFVKESFDIGAVRLTEKFIKNDPPTAEEYDEIRLHI
CCCCCCEEEEEECCCCCHHHHCCHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHH
IDTMVNSINKYKEVENVIGIGGTITTLAAVSQQLEIYSQEKVHGYQLKKEEIKRILDKFM
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
SVTLEERKKFFGLQPQRADIIIAGTAILLTILEMLSFKEITVSEWDNLEGAVLYKFREFK
HHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHCCCCCCHHCCCCCCCEEEEEEECCC
L
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]