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The map label for this gene is trpE [H]

Identifier: 167039274

GI number: 167039274

Start: 638389

End: 639693

Strand: Direct

Name: trpE [H]

Synonym: Teth514_0615

Alternate gene names: 167039274

Gene position: 638389-639693 (Clockwise)

Preceding gene: 167039273

Following gene: 167039275

Centisome position: 25.98

GC content: 34.18

Gene sequence:

>1305_bases
ATGGTTGTGTATGATAGTCTTTTAAATCCTTTTGATGTGTTTTGCTATCTGAATGATAAATTTTCAATACTACTTGAGAG
CAATCTATTTAACAAAAACTTTGGAAGATATTCTTTCTTGTTTGTAAACCCCAAAGATGTGTTTATTTGCAATGATGAAG
ATGATGTGTCTGAGTTTCTGCAAAGGCTTTCGGAAGAGGTTTTAAAAAGAAGAGAAGATTCAGAATTTATTTTCAATGGT
GGTTTTGCAGGATACTTTTCTTACAATTTTGGAGTGGACCTTTACAATGTTAAAAGAAAGAAAGATGTGTCATCAGTTTA
TAAAGCTTTCTTTGGGTACTACGAGGATTTCATTGTTCTTGACCATCTTGAAAAAAAGATGTATGTAAGTCTATCTTCAA
AAGAGCATTTAGAAAAGATTGATAAGCTTTTAAAAAGTCCAAGCTCTTTTGTGATGGAATTTAAAAGACCAGTTGTTGAA
GAATTTGTTACCAACTTTGAAAAGAAAGAATACAAAGCGTGTATAAAAAAGATCAAAAATTACATATATGAAGGGGATGT
TTATCAAGTAAACTTGTCCCAGCGCTTTGTGTTCAAAGGCAGCTTTGACCCAGATTATGTATATTCAACTTTAAGGTCAA
AAAACTATGGTGCATACCATGCATATATAAAGCTACCAAAAGCAAGTATTATCTCAACATCACCTGAGCTTTTCTTGAGA
AAAAGAGGTAAAACCATAATAACAAAGCCTATCAAAGGGACAATCAGAAGGGGTAAGGATGAGGAAGAAGACAAGAGATT
GAAAGAGATTCTTTTAAATGATGAGAAATGCCGTGCAGAGCTTTTGATGATAGTTGACCTTGAGAGAAATGATTTTGCAA
AGATATGTACACCACATACAATCACTTTGGAAAAACTTTTTGAGGTTGAGGAGTACTCAAGTGTGTTTCATCTTGTTTCA
ACAATCAAAGGCGACTTGAAAGAGGGAGTGGAGCTTGATAGCATAATAAAAGCAACATTTCCGGGCGGTTCTATCACAGG
TGCCCCAAAGTTAAATGCAATTAAGATAATCGAAGAGTTAGAAAAGGACCCAAGAGGTATATACACAGGTTCAATAGGGT
ATATTTCAAACAACTTCAACATGGATTTCAATATTGCAATCAGGACCTTAGTGATAGAAGGCAATACTGCTTATTTTAAT
GTTGGCGGCGGGATTGTATGGGATTCTACTGAAGAAGATGAGTATGAAGAGACACTCCACAAAGGAAAACCTATTTTTGA
TATTTTGATAGGCAAAAACATGTGA

Upstream 100 bases:

>100_bases
TTATCAAATTGAAGGTGTTCAGTTTCATCCAGAATCGATTGCAACAGAAGATGGGCTTTTGATGATAGAAAACTTTTTAA
GAGGGTGAAGTTTTTTGAAG

Downstream 100 bases:

>100_bases
AATTTTTGAAATAGGGGGACGATTATAAATTGTTTTTTGAAGATGATTTTGATAGCTTTAATCTTGGGCTTGTTCCTTTT
GACACAATATATTATAAAAA

Product: para-aminobenzoate synthase subunit I

Products: NA

Alternate protein names: Anthranilate synthase component I [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MVVYDSLLNPFDVFCYLNDKFSILLESNLFNKNFGRYSFLFVNPKDVFICNDEDDVSEFLQRLSEEVLKRREDSEFIFNG
GFAGYFSYNFGVDLYNVKRKKDVSSVYKAFFGYYEDFIVLDHLEKKMYVSLSSKEHLEKIDKLLKSPSSFVMEFKRPVVE
EFVTNFEKKEYKACIKKIKNYIYEGDVYQVNLSQRFVFKGSFDPDYVYSTLRSKNYGAYHAYIKLPKASIISTSPELFLR
KRGKTIITKPIKGTIRRGKDEEEDKRLKEILLNDEKCRAELLMIVDLERNDFAKICTPHTITLEKLFEVEEYSSVFHLVS
TIKGDLKEGVELDSIIKATFPGGSITGAPKLNAIKIIEELEKDPRGIYTGSIGYISNNFNMDFNIAIRTLVIEGNTAYFN
VGGGIVWDSTEEDEYEETLHKGKPIFDILIGKNM

Sequences:

>Translated_434_residues
MVVYDSLLNPFDVFCYLNDKFSILLESNLFNKNFGRYSFLFVNPKDVFICNDEDDVSEFLQRLSEEVLKRREDSEFIFNG
GFAGYFSYNFGVDLYNVKRKKDVSSVYKAFFGYYEDFIVLDHLEKKMYVSLSSKEHLEKIDKLLKSPSSFVMEFKRPVVE
EFVTNFEKKEYKACIKKIKNYIYEGDVYQVNLSQRFVFKGSFDPDYVYSTLRSKNYGAYHAYIKLPKASIISTSPELFLR
KRGKTIITKPIKGTIRRGKDEEEDKRLKEILLNDEKCRAELLMIVDLERNDFAKICTPHTITLEKLFEVEEYSSVFHLVS
TIKGDLKEGVELDSIIKATFPGGSITGAPKLNAIKIIEELEKDPRGIYTGSIGYISNNFNMDFNIAIRTLVIEGNTAYFN
VGGGIVWDSTEEDEYEETLHKGKPIFDILIGKNM
>Mature_434_residues
MVVYDSLLNPFDVFCYLNDKFSILLESNLFNKNFGRYSFLFVNPKDVFICNDEDDVSEFLQRLSEEVLKRREDSEFIFNG
GFAGYFSYNFGVDLYNVKRKKDVSSVYKAFFGYYEDFIVLDHLEKKMYVSLSSKEHLEKIDKLLKSPSSFVMEFKRPVVE
EFVTNFEKKEYKACIKKIKNYIYEGDVYQVNLSQRFVFKGSFDPDYVYSTLRSKNYGAYHAYIKLPKASIISTSPELFLR
KRGKTIITKPIKGTIRRGKDEEEDKRLKEILLNDEKCRAELLMIVDLERNDFAKICTPHTITLEKLFEVEEYSSVFHLVS
TIKGDLKEGVELDSIIKATFPGGSITGAPKLNAIKIIEELEKDPRGIYTGSIGYISNNFNMDFNIAIRTLVIEGNTAYFN
VGGGIVWDSTEEDEYEETLHKGKPIFDILIGKNM

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=417, Percent_Identity=33.8129496402878, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI1787518, Length=374, Percent_Identity=28.3422459893048, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI87082077, Length=269, Percent_Identity=26.3940520446097, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1786809, Length=301, Percent_Identity=24.2524916943522, Blast_Score=75, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6320935, Length=465, Percent_Identity=32.9032258064516, Blast_Score=212, Evalue=1e-55,
Organism=Saccharomyces cerevisiae, GI6324361, Length=392, Percent_Identity=27.2959183673469, Blast_Score=126, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR005256
- InterPro:   IPR015890 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 50245; Mature: 50245

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVYDSLLNPFDVFCYLNDKFSILLESNLFNKNFGRYSFLFVNPKDVFICNDEDDVSEFL
CEEEHHHCCCEEEEEEECCCEEEEEECCCCCCCCCCEEEEEECCCEEEEECCCHHHHHHH
QRLSEEVLKRREDSEFIFNGGFAGYFSYNFGVDLYNVKRKKDVSSVYKAFFGYYEDFIVL
HHHHHHHHHCCCCCCEEEECCEEEEEEEECCEEEEECHHHHHHHHHHHHHHHHHHHHHHH
DHLEKKMYVSLSSKEHLEKIDKLLKSPSSFVMEFKRPVVEEFVTNFEKKEYKACIKKIKN
HHHCCEEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YIYEGDVYQVNLSQRFVFKGSFDPDYVYSTLRSKNYGAYHAYIKLPKASIISTSPELFLR
HHCCCCEEEEECCEEEEEECCCCHHHHHHHHHCCCCCEEEEEEECCCHHHCCCCHHHHHH
KRGKTIITKPIKGTIRRGKDEEEDKRLKEILLNDEKCRAELLMIVDLERNDFAKICTPHT
HCCCEEEECCCHHHHHCCCCCHHHHHHHHHHCCCCHHCEEEEEEEEECCCCCHHHCCCCE
ITLEKLFEVEEYSSVFHLVSTIKGDLKEGVELDSIIKATFPGGSITGAPKLNAIKIIEEL
EEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHEEECCCCCCCCCCCCHHHHHHHHH
EKDPRGIYTGSIGYISNNFNMDFNIAIRTLVIEGNTAYFNVGGGIVWDSTEEDEYEETLH
CCCCCCEEECEEEEEECCCCEEEEEEEEEEEEECCEEEEECCCEEEECCCCCHHHHHHHH
KGKPIFDILIGKNM
CCCCEEEEEECCCC
>Mature Secondary Structure
MVVYDSLLNPFDVFCYLNDKFSILLESNLFNKNFGRYSFLFVNPKDVFICNDEDDVSEFL
CEEEHHHCCCEEEEEEECCCEEEEEECCCCCCCCCCEEEEEECCCEEEEECCCHHHHHHH
QRLSEEVLKRREDSEFIFNGGFAGYFSYNFGVDLYNVKRKKDVSSVYKAFFGYYEDFIVL
HHHHHHHHHCCCCCCEEEECCEEEEEEEECCEEEEECHHHHHHHHHHHHHHHHHHHHHHH
DHLEKKMYVSLSSKEHLEKIDKLLKSPSSFVMEFKRPVVEEFVTNFEKKEYKACIKKIKN
HHHCCEEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YIYEGDVYQVNLSQRFVFKGSFDPDYVYSTLRSKNYGAYHAYIKLPKASIISTSPELFLR
HHCCCCEEEEECCEEEEEECCCCHHHHHHHHHCCCCCEEEEEEECCCHHHCCCCHHHHHH
KRGKTIITKPIKGTIRRGKDEEEDKRLKEILLNDEKCRAELLMIVDLERNDFAKICTPHT
HCCCEEEECCCHHHHHCCCCCHHHHHHHHHHCCCCHHCEEEEEEEEECCCCCHHHCCCCE
ITLEKLFEVEEYSSVFHLVSTIKGDLKEGVELDSIIKATFPGGSITGAPKLNAIKIIEEL
EEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHEEECCCCCCCCCCCCHHHHHHHHH
EKDPRGIYTGSIGYISNNFNMDFNIAIRTLVIEGNTAYFNVGGGIVWDSTEEDEYEETLH
CCCCCCEEECEEEEEECCCCEEEEEEEEEEEEECCEEEEECCCEEEECCCCCHHHHHHHH
KGKPIFDILIGKNM
CCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]