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The map label for this gene is ddl

Identifier: 167039269

GI number: 167039269

Start: 632897

End: 633976

Strand: Direct

Name: ddl

Synonym: Teth514_0610

Alternate gene names: 167039269

Gene position: 632897-633976 (Clockwise)

Preceding gene: 167039268

Following gene: 167039270

Centisome position: 25.76

GC content: 35.19

Gene sequence:

>1080_bases
ATGGAAAAGAAGAAAATAGCTGTTTTATTTGGCGGACAATCAGGAGAACATGAAGTTTCTTTAATGTCTGCAAAGTCTAT
AATAAACAACCTTGATAAAGATAAATACGAGATTTACATGGTAGGTATTACAAAAAAAGGAGAATGGTATCTGTATAGAG
GAGATGTGGGGAAAATAGAAACTGGAGAATGGGAAAAAGAAGGAATTCCTGCAATTATGGGAGCTTCTACAAAGTATAGA
GGAATAATAACTTTCGAAGATGGAGAAAACGGTTTTTATCCTATAGACGTGGTATTTCCTGTTTTACATGGTCCTAATGG
AGAAGATGGGACTATACAAGGGCTTTTAGAACTATTAGACATGCCTTATGTAGGTGCTAATGTGCTTTCTTCTGCTTTAT
GCATGGATAAAGTTTTTACAAAAAGAATTTTTAAGGAAGCGGGGTTACCTACACCTGATTTTGTAGTAGTGTATGGAAAA
GAGATTGAAGACTTAGAAGCTATAAAGAAAAAAATTGAACACTTAGGATATCCTTGTTTTGTAAAACCTGCTAATTTGGG
GTCGAGTGTTGGCATTACTAAAGTCCACAACGAGGAAGAACTTCCTGGGGCCTTGAAATTAGCTGCGAAATATGATAGAA
AATTATTAATAGAAAGAGGAATAGATGCCAGAGAGATTGAATGCTCTGTTTTGGGTAATGAAAATCCCGAGGCCTCTATT
GCAGGAGAAATTGTTCCTTCTAATGAATTCTATGATTATAATGCTAAATATTTTGATGGGGGTAAATCTCTTCTCTTAAT
ACCTGCACCACTTCCAGATGAAAAAATGGAAGAGGTAAGAAAGCTTGCTATAAAGGCCTACAAAGCTTTGGATTTGAGAG
GTATGGCGAGAGTAGACTTTTTAATGGATAGAAATACAGGTACTCTTTATTTAAATGAAGTTAATACCATTCCGGGGTTT
ACAAAAATAAGCATGTATCCCAAATTATGGGAATCAAGTGGAAAGTCTTATTCAACATTATTGGATGAGCTTATAAACTT
AGCAGTAGAGAGCCATAATGAAAAATGTAGGGAATGGTGA

Upstream 100 bases:

>100_bases
TTCCCGGCTTTAAATTTATAAAATAAAATTTTTCTTGAATACATATTCTTAAAAGAGTAGAATAAAGATAATGTAAGAAA
AATTAGTGGAGTGTGAGAGA

Downstream 100 bases:

>100_bases
GAAATAAGGGAAGAAGGGGAGAGGTAATTGAAAAAAGCGATTATATCCGTAAAAGGTACTCAAAAAAACGATCAAAATGA
ATCTGATACAATAGAACTTA

Product: D-alanyl-alanine synthetase A

Products: NA

Alternate protein names: D-Ala-D-Ala ligase; D-alanylalanine synthetase

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MEKKKIAVLFGGQSGEHEVSLMSAKSIINNLDKDKYEIYMVGITKKGEWYLYRGDVGKIETGEWEKEGIPAIMGASTKYR
GIITFEDGENGFYPIDVVFPVLHGPNGEDGTIQGLLELLDMPYVGANVLSSALCMDKVFTKRIFKEAGLPTPDFVVVYGK
EIEDLEAIKKKIEHLGYPCFVKPANLGSSVGITKVHNEEELPGALKLAAKYDRKLLIERGIDAREIECSVLGNENPEASI
AGEIVPSNEFYDYNAKYFDGGKSLLLIPAPLPDEKMEEVRKLAIKAYKALDLRGMARVDFLMDRNTGTLYLNEVNTIPGF
TKISMYPKLWESSGKSYSTLLDELINLAVESHNEKCREW

Sequences:

>Translated_359_residues
MEKKKIAVLFGGQSGEHEVSLMSAKSIINNLDKDKYEIYMVGITKKGEWYLYRGDVGKIETGEWEKEGIPAIMGASTKYR
GIITFEDGENGFYPIDVVFPVLHGPNGEDGTIQGLLELLDMPYVGANVLSSALCMDKVFTKRIFKEAGLPTPDFVVVYGK
EIEDLEAIKKKIEHLGYPCFVKPANLGSSVGITKVHNEEELPGALKLAAKYDRKLLIERGIDAREIECSVLGNENPEASI
AGEIVPSNEFYDYNAKYFDGGKSLLLIPAPLPDEKMEEVRKLAIKAYKALDLRGMARVDFLMDRNTGTLYLNEVNTIPGF
TKISMYPKLWESSGKSYSTLLDELINLAVESHNEKCREW
>Mature_359_residues
MEKKKIAVLFGGQSGEHEVSLMSAKSIINNLDKDKYEIYMVGITKKGEWYLYRGDVGKIETGEWEKEGIPAIMGASTKYR
GIITFEDGENGFYPIDVVFPVLHGPNGEDGTIQGLLELLDMPYVGANVLSSALCMDKVFTKRIFKEAGLPTPDFVVVYGK
EIEDLEAIKKKIEHLGYPCFVKPANLGSSVGITKVHNEEELPGALKLAAKYDRKLLIERGIDAREIECSVLGNENPEASI
AGEIVPSNEFYDYNAKYFDGGKSLLLIPAPLPDEKMEEVRKLAIKAYKALDLRGMARVDFLMDRNTGTLYLNEVNTIPGF
TKISMYPKLWESSGKSYSTLLDELINLAVESHNEKCREW

Specific function: Cell wall formation

COG id: COG1181

COG function: function code M; D-alanine-D-alanine ligase and related ATP-grasp enzymes

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Escherichia coli, GI1786579, Length=357, Percent_Identity=42.296918767507, Blast_Score=306, Evalue=2e-84,
Organism=Escherichia coli, GI1786280, Length=346, Percent_Identity=34.6820809248555, Blast_Score=181, Evalue=7e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DDL_THEP3 (B0KBI1)

Other databases:

- EMBL:   CP000924
- RefSeq:   YP_001664196.1
- ProteinModelPortal:   B0KBI1
- GeneID:   5875521
- GenomeReviews:   CP000924_GR
- KEGG:   tpd:Teth39_0187
- HOGENOM:   HBG427092
- OMA:   FTDISMY
- ProtClustDB:   PRK01966
- BioCyc:   TPSE340099:TETH39_0187-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00047
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR000291
- InterPro:   IPR005905
- InterPro:   IPR011095
- InterPro:   IPR011127
- InterPro:   IPR013817
- InterPro:   IPR016185
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.20
- TIGRFAMs:   TIGR01205

Pfam domain/function: PF07478 Dala_Dala_lig_C; PF01820 Dala_Dala_lig_N; SSF52440 PreATP-grasp-like

EC number: =6.3.2.4

Molecular weight: Translated: 40084; Mature: 40084

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS50975 ATP_GRASP; PS00843 DALA_DALA_LIGASE_1; PS00844 DALA_DALA_LIGASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKKKIAVLFGGQSGEHEVSLMSAKSIINNLDKDKYEIYMVGITKKGEWYLYRGDVGKIE
CCCCEEEEEECCCCCCCEEHHHHHHHHHHHCCCCCEEEEEEEEEECCCEEEEECCCCCCC
TGEWEKEGIPAIMGASTKYRGIITFEDGENGFYPIDVVFPVLHGPNGEDGTIQGLLELLD
CCCCCCCCCCEEECCCCCEEEEEEEECCCCCEEEHEEEEEEEECCCCCCHHHHHHHHHHC
MPYVGANVLSSALCMDKVFTKRIFKEAGLPTPDFVVVYGKEIEDLEAIKKKIEHLGYPCF
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCEE
VKPANLGSSVGITKVHNEEELPGALKLAAKYDRKLLIERGIDAREIECSVLGNENPEASI
EECCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCE
AGEIVPSNEFYDYNAKYFDGGKSLLLIPAPLPDEKMEEVRKLAIKAYKALDLRGMARVDF
EEEEECCCCCEECCCEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEE
LMDRNTGTLYLNEVNTIPGFTKISMYPKLWESSGKSYSTLLDELINLAVESHNEKCREW
EEECCCCEEEEEECCCCCCCEEEECCHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure
MEKKKIAVLFGGQSGEHEVSLMSAKSIINNLDKDKYEIYMVGITKKGEWYLYRGDVGKIE
CCCCEEEEEECCCCCCCEEHHHHHHHHHHHCCCCCEEEEEEEEEECCCEEEEECCCCCCC
TGEWEKEGIPAIMGASTKYRGIITFEDGENGFYPIDVVFPVLHGPNGEDGTIQGLLELLD
CCCCCCCCCCEEECCCCCEEEEEEEECCCCCEEEHEEEEEEEECCCCCCHHHHHHHHHHC
MPYVGANVLSSALCMDKVFTKRIFKEAGLPTPDFVVVYGKEIEDLEAIKKKIEHLGYPCF
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCEE
VKPANLGSSVGITKVHNEEELPGALKLAAKYDRKLLIERGIDAREIECSVLGNENPEASI
EECCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCE
AGEIVPSNEFYDYNAKYFDGGKSLLLIPAPLPDEKMEEVRKLAIKAYKALDLRGMARVDF
EEEEECCCCCEECCCEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEE
LMDRNTGTLYLNEVNTIPGFTKISMYPKLWESSGKSYSTLLDELINLAVESHNEKCREW
EEECCCCEEEEEECCCCCCCEEEECCHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA