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The map label for this gene is murC [H]

Identifier: 167039242

GI number: 167039242

Start: 604885

End: 606279

Strand: Reverse

Name: murC [H]

Synonym: Teth514_0583

Alternate gene names: 167039242

Gene position: 606279-604885 (Counterclockwise)

Preceding gene: 167039276

Following gene: 167039239

Centisome position: 24.67

GC content: 32.97

Gene sequence:

>1395_bases
ATGGATATAAATCTTGAAAACTTTAAAAGAGTGCATTTTATAGGAATTGGCGGTATAAGTATGAGCGGTTTAGCTCATAT
ACTTTTGAATAACGGCCATATAGTAACAGGCTCAGATATAAAAAATTCTCATATAATCGAAAGGTTAAGACAAGAAGGAG
CAGTTATAACAATACCTCACAATGAAAATAGTGTCATAGGTGCTGATTTAGTAGTGTATACAGCTGCTATCCATGAAGAT
AATCCTGAATATCAAAAGGCTAAAGAATTAAATATACCTACTATAGATAGAGCTACCCTTTTAGGTCTCATTATGAAAAA
ATACAAATACGGCATTGCTGTTGCAGGAAGTCATGGAAAGACAACTACTACTTCTTTAATATCTGTAATACTCGATGGTA
TGGGATTTGACCCAACAGTTTTAGTAGGAGGAGAAGTAGATGTAATAGGAGGAAATGTGAAAGTTGGAAACAGTGAATAT
TTTGTCACAGAAGCTTGTGAATATACAGATAGTTTTCTAAAGTTTTATCCTTACATAGCTGTTATACTAAATGTCGATTC
AGATCACTTAGATTACTTCAAAAATATTGACAACATAAAGCAGTCTTTTAGGCAATTTGCTAATTTAGTTCCACCAGATG
GATTTGTGGTAGCATGCAAAGATGATGCAAACACCATGTATGTTGTAAATGGGCTAAATAAAAACATTGTAACCTATGGT
ATTTACCAAGATAGTGATTGGAAAGCAAAAAGCATAAGTTTTGATGATAAAGGTTGTGCAATTTTTGATGTTTATTATAA
AGAGGAATATATGGGCAATTTTAAATTATCAATACCCGGAAAACACAATGTTTACAACGCCTTAGCTGCTTTGGCAGTAA
GTCACCTTGTAGGAATCGACATAAAAAAAGCTTCTCATTATTTAACTGAGTTCAAAGGCACTCATAGAAGATTCGAAGTA
AAAGGAATAGTTGACGGCATAACAATTGTGGATGACTATGCTCATCACCCTGCTGAAATTAAAGCAACTTTAGAAGCAGC
AAAAAATTATCCTCATAAAAGAATTATTTGTATATTCCAGCCACATACTTACTCAAGAACTAAATCTTTGCTTAATGATT
TTGCAGAGTCCTTTGACAATGCGGATAAAATAATAATAGCTGACATATACGCCGCAAGAGAGAAAGATACAGGAATTGTT
TCTTCTAAAGATTTAGTGGAACTAATCTCTCAAAGAGGAAAGGATGTTTTGTACTTAAAAGACTTTGACTCTATAGTGGA
GTATTTAAATAAAAATGCAAAAGCAGGCGATTTAGTATTAACAGTTGGAGCAGGAAATATCTACGAAGTAGGAGAAATGT
TTTTAAAAGGCCATAAAAAAGCTGTAGGAATGTAA

Upstream 100 bases:

>100_bases
TATAATTTTTTTATAAATATAGTTGCTTTTGACAAGCTTTAATCATATTTTAACCATGAAAAGGCAATAATAACAATAGG
AACTGAGAGGAGCGTAAACT

Downstream 100 bases:

>100_bases
ACCCTACAGCTTTTCATCTTGCAACACAAGATTTCCTCTCCACAAGCTTCACAGGCACAATTATATGGTCTATGTCTATC
TCCTTTTGCTTTAACCTCGC

Product: UDP-N-acetylmuramate--L-alanine ligase

Products: NA

Alternate protein names: UDP-N-acetylmuramoyl-L-alanine synthetase [H]

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MDINLENFKRVHFIGIGGISMSGLAHILLNNGHIVTGSDIKNSHIIERLRQEGAVITIPHNENSVIGADLVVYTAAIHED
NPEYQKAKELNIPTIDRATLLGLIMKKYKYGIAVAGSHGKTTTTSLISVILDGMGFDPTVLVGGEVDVIGGNVKVGNSEY
FVTEACEYTDSFLKFYPYIAVILNVDSDHLDYFKNIDNIKQSFRQFANLVPPDGFVVACKDDANTMYVVNGLNKNIVTYG
IYQDSDWKAKSISFDDKGCAIFDVYYKEEYMGNFKLSIPGKHNVYNALAALAVSHLVGIDIKKASHYLTEFKGTHRRFEV
KGIVDGITIVDDYAHHPAEIKATLEAAKNYPHKRIICIFQPHTYSRTKSLLNDFAESFDNADKIIIADIYAAREKDTGIV
SSKDLVELISQRGKDVLYLKDFDSIVEYLNKNAKAGDLVLTVGAGNIYEVGEMFLKGHKKAVGM

Sequences:

>Translated_464_residues
MDINLENFKRVHFIGIGGISMSGLAHILLNNGHIVTGSDIKNSHIIERLRQEGAVITIPHNENSVIGADLVVYTAAIHED
NPEYQKAKELNIPTIDRATLLGLIMKKYKYGIAVAGSHGKTTTTSLISVILDGMGFDPTVLVGGEVDVIGGNVKVGNSEY
FVTEACEYTDSFLKFYPYIAVILNVDSDHLDYFKNIDNIKQSFRQFANLVPPDGFVVACKDDANTMYVVNGLNKNIVTYG
IYQDSDWKAKSISFDDKGCAIFDVYYKEEYMGNFKLSIPGKHNVYNALAALAVSHLVGIDIKKASHYLTEFKGTHRRFEV
KGIVDGITIVDDYAHHPAEIKATLEAAKNYPHKRIICIFQPHTYSRTKSLLNDFAESFDNADKIIIADIYAAREKDTGIV
SSKDLVELISQRGKDVLYLKDFDSIVEYLNKNAKAGDLVLTVGAGNIYEVGEMFLKGHKKAVGM
>Mature_464_residues
MDINLENFKRVHFIGIGGISMSGLAHILLNNGHIVTGSDIKNSHIIERLRQEGAVITIPHNENSVIGADLVVYTAAIHED
NPEYQKAKELNIPTIDRATLLGLIMKKYKYGIAVAGSHGKTTTTSLISVILDGMGFDPTVLVGGEVDVIGGNVKVGNSEY
FVTEACEYTDSFLKFYPYIAVILNVDSDHLDYFKNIDNIKQSFRQFANLVPPDGFVVACKDDANTMYVVNGLNKNIVTYG
IYQDSDWKAKSISFDDKGCAIFDVYYKEEYMGNFKLSIPGKHNVYNALAALAVSHLVGIDIKKASHYLTEFKGTHRRFEV
KGIVDGITIVDDYAHHPAEIKATLEAAKNYPHKRIICIFQPHTYSRTKSLLNDFAESFDNADKIIIADIYAAREKDTGIV
SSKDLVELISQRGKDVLYLKDFDSIVEYLNKNAKAGDLVLTVGAGNIYEVGEMFLKGHKKAVGM

Specific function: Cell wall formation [H]

COG id: COG0773

COG function: function code M; UDP-N-acetylmuramate-alanine ligase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MurCDEF family [H]

Homologues:

Organism=Escherichia coli, GI1786279, Length=461, Percent_Identity=35.1409978308026, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI1790680, Length=474, Percent_Identity=28.0590717299578, Blast_Score=190, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004101
- InterPro:   IPR013221
- InterPro:   IPR000713
- InterPro:   IPR016040
- InterPro:   IPR005758 [H]

Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]

EC number: =6.3.2.8 [H]

Molecular weight: Translated: 51424; Mature: 51424

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDINLENFKRVHFIGIGGISMSGLAHILLNNGHIVTGSDIKNSHIIERLRQEGAVITIPH
CCCCHHHCCEEEEEEECCCCHHCEEEEEEECCEEEECCCCCHHHHHHHHHHCCCEEEEEC
NENSVIGADLVVYTAAIHEDNPEYQKAKELNIPTIDRATLLGLIMKKYKYGIAVAGSHGK
CCCCEEECHHEEEEEECCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEECCCCC
TTTTSLISVILDGMGFDPTVLVGGEVDVIGGNVKVGNSEYFVTEACEYTDSFLKFYPYIA
HHHHHHHHHHHHCCCCCCEEEECCEEEEECCEEEECCCCEEEEHHHHHHHHHHHHHCEEE
VILNVDSDHLDYFKNIDNIKQSFRQFANLVPPDGFVVACKDDANTMYVVNGLNKNIVTYG
EEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCEEEEE
IYQDSDWKAKSISFDDKGCAIFDVYYKEEYMGNFKLSIPGKHNVYNALAALAVSHLVGID
EEECCCCCEEECCCCCCCCEEEEEEEHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHCCC
IKKASHYLTEFKGTHRRFEVKGIVDGITIVDDYAHHPAEIKATLEAAKNYPHKRIICIFQ
HHHHHHHHHHHCCCCEEEEEEEEECCEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEEEC
PHTYSRTKSLLNDFAESFDNADKIIIADIYAAREKDTGIVSSKDLVELISQRGKDVLYLK
CCCCHHHHHHHHHHHHHHCCCCEEEEEEEEHHCCCCCCCCCHHHHHHHHHHCCCEEEEEC
DFDSIVEYLNKNAKAGDLVLTVGAGNIYEVGEMFLKGHKKAVGM
CHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure
MDINLENFKRVHFIGIGGISMSGLAHILLNNGHIVTGSDIKNSHIIERLRQEGAVITIPH
CCCCHHHCCEEEEEEECCCCHHCEEEEEEECCEEEECCCCCHHHHHHHHHHCCCEEEEEC
NENSVIGADLVVYTAAIHEDNPEYQKAKELNIPTIDRATLLGLIMKKYKYGIAVAGSHGK
CCCCEEECHHEEEEEECCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEECCCCC
TTTTSLISVILDGMGFDPTVLVGGEVDVIGGNVKVGNSEYFVTEACEYTDSFLKFYPYIA
HHHHHHHHHHHHCCCCCCEEEECCEEEEECCEEEECCCCEEEEHHHHHHHHHHHHHCEEE
VILNVDSDHLDYFKNIDNIKQSFRQFANLVPPDGFVVACKDDANTMYVVNGLNKNIVTYG
EEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCEEEEE
IYQDSDWKAKSISFDDKGCAIFDVYYKEEYMGNFKLSIPGKHNVYNALAALAVSHLVGID
EEECCCCCEEECCCCCCCCEEEEEEEHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHCCC
IKKASHYLTEFKGTHRRFEVKGIVDGITIVDDYAHHPAEIKATLEAAKNYPHKRIICIFQ
HHHHHHHHHHHCCCCEEEEEEEEECCEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEEEC
PHTYSRTKSLLNDFAESFDNADKIIIADIYAAREKDTGIVSSKDLVELISQRGKDVLYLK
CCCCHHHHHHHHHHHHHHCCCCEEEEEEEEHHCCCCCCCCCHHHHHHHHHHCCCEEEEEC
DFDSIVEYLNKNAKAGDLVLTVGAGNIYEVGEMFLKGHKKAVGM
CHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]