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The map label for this gene is purQ [H]

Identifier: 167039179

GI number: 167039179

Start: 534802

End: 535476

Strand: Direct

Name: purQ [H]

Synonym: Teth514_0520

Alternate gene names: 167039179

Gene position: 534802-535476 (Clockwise)

Preceding gene: 167039178

Following gene: 167039180

Centisome position: 21.76

GC content: 36.59

Gene sequence:

>675_bases
ATGAAATTTGCTGTTATAGTTTTTCCAGGGTCCAATTGCGATGTGGACTGCTATTATGCTGTTAAAGATGGGCTTGGGGA
AGAAGTAGAATATGTATGGCATCAAGAAAAAAATTTGAGTAAGTACGATGTTATAATGTTACCAGGAGGATTTTCTTATG
GTGATTATTTGAGGGCAGGAGCTATTGCTAGGTTTTCGCCTGTCATGGAGGCTGTCAGGGAAGAAGCAGAAAAAGGAAAA
TTTATTATAGGCATATGCAACGGATTTCAGATACTTACAGAAGCAGGGCTTTTGCCGGGAGCTTTGAGAAAAAATGAAGG
TCTGAAATTTATTTGCAATACTGTCAGCATAATAGTTGAAAATGACAAAACTCCTTTTACTACAAGGCTTAAAAAAGGGC
AGGAGATTTTACTTCCAATTGCTCATGGAGAAGGCAATTATTATGTAGATGACAAAACTTTAAAAGAACTAAAAGAAAAC
AATCAAATTGTTTTTAGGTACAAAGAAAATATCAACGGCTCTGTTGAGAGAATAGCCGGAGTTATAAATAAAAAAGGAAA
TGTTTTAGGAATGATGCCTCATCCAGAGAGAGCTTATGCCCCCTTGCTGGGTAATACTGACGGGCTTTATATCTTAGGGT
CAATAATGGATAATTTTGTAAAAGGCGGGGTTTAA

Upstream 100 bases:

>100_bases
ATTTATCCCTCCTAAAGGACAAAGTAGATGAGATGTGCAAAAGGATACTGACAAACCCAATTATTGAAGATTACACCTTT
GAAATTGTGGAGGGATAAAG

Downstream 100 bases:

>100_bases
GGATGGATAAAATATGGAGAGAATTAGGACTTACTGATGAGGAGTATGAGAAGATTATTTCGATATTAGGAAGAGAGCCT
AATATAACTGAAATAGGTAT

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MKFAVIVFPGSNCDVDCYYAVKDGLGEEVEYVWHQEKNLSKYDVIMLPGGFSYGDYLRAGAIARFSPVMEAVREEAEKGK
FIIGICNGFQILTEAGLLPGALRKNEGLKFICNTVSIIVENDKTPFTTRLKKGQEILLPIAHGEGNYYVDDKTLKELKEN
NQIVFRYKENINGSVERIAGVINKKGNVLGMMPHPERAYAPLLGNTDGLYILGSIMDNFVKGGV

Sequences:

>Translated_224_residues
MKFAVIVFPGSNCDVDCYYAVKDGLGEEVEYVWHQEKNLSKYDVIMLPGGFSYGDYLRAGAIARFSPVMEAVREEAEKGK
FIIGICNGFQILTEAGLLPGALRKNEGLKFICNTVSIIVENDKTPFTTRLKKGQEILLPIAHGEGNYYVDDKTLKELKEN
NQIVFRYKENINGSVERIAGVINKKGNVLGMMPHPERAYAPLLGNTDGLYILGSIMDNFVKGGV
>Mature_224_residues
MKFAVIVFPGSNCDVDCYYAVKDGLGEEVEYVWHQEKNLSKYDVIMLPGGFSYGDYLRAGAIARFSPVMEAVREEAEKGK
FIIGICNGFQILTEAGLLPGALRKNEGLKFICNTVSIIVENDKTPFTTRLKKGQEILLPIAHGEGNYYVDDKTLKELKEN
NQIVFRYKENINGSVERIAGVINKKGNVLGMMPHPERAYAPLLGNTDGLYILGSIMDNFVKGGV

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=187, Percent_Identity=29.4117647058824, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321498, Length=181, Percent_Identity=31.4917127071823, Blast_Score=65, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24582111, Length=193, Percent_Identity=29.5336787564767, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24582109, Length=193, Percent_Identity=29.5336787564767, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI17137292, Length=193, Percent_Identity=29.5336787564767, Blast_Score=78, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 24851; Mature: 24851

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFAVIVFPGSNCDVDCYYAVKDGLGEEVEYVWHQEKNLSKYDVIMLPGGFSYGDYLRAG
CEEEEEEECCCCCCEEEEEEECCCCCCHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHC
AIARFSPVMEAVREEAEKGKFIIGICNGFQILTEAGLLPGALRKNEGLKFICNTVSIIVE
CHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHCCCCCCCCCCCCCCEEEEEEEEEEEE
NDKTPFTTRLKKGQEILLPIAHGEGNYYVDDKTLKELKENNQIVFRYKENINGSVERIAG
CCCCCHHHHHCCCCEEEEEEEECCCCEEECHHHHHHHHCCCEEEEEEECCCCCHHHHHHH
VINKKGNVLGMMPHPERAYAPLLGNTDGLYILGSIMDNFVKGGV
HHCCCCCEEEECCCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCC
>Mature Secondary Structure
MKFAVIVFPGSNCDVDCYYAVKDGLGEEVEYVWHQEKNLSKYDVIMLPGGFSYGDYLRAG
CEEEEEEECCCCCCEEEEEEECCCCCCHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHC
AIARFSPVMEAVREEAEKGKFIIGICNGFQILTEAGLLPGALRKNEGLKFICNTVSIIVE
CHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHCCCCCCCCCCCCCCEEEEEEEEEEEE
NDKTPFTTRLKKGQEILLPIAHGEGNYYVDDKTLKELKENNQIVFRYKENINGSVERIAG
CCCCCHHHHHCCCCEEEEEEEECCCCEEECHHHHHHHHCCCEEEEEEECCCCCHHHHHHH
VINKKGNVLGMMPHPERAYAPLLGNTDGLYILGSIMDNFVKGGV
HHCCCCCEEEECCCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]