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The map label for this gene is gcp [H]

Identifier: 167039152

GI number: 167039152

Start: 504982

End: 506004

Strand: Direct

Name: gcp [H]

Synonym: Teth514_0491

Alternate gene names: 167039152

Gene position: 504982-506004 (Clockwise)

Preceding gene: 167039151

Following gene: 167039153

Centisome position: 20.55

GC content: 37.44

Gene sequence:

>1023_bases
ATGGAGAAAGATATAATTATTTTAGGAATAGAATCTTCCTGCGATGAAACAGCTGCAGGAGTTGTAAAAAACGGCAAAGA
AGTATTGTCGAACGTAATATATTCTCAAATAGAGATTCACAAAAAATATGGTGGGGTAGTGCCAGAAATAGCTTCAAGAA
AGCATATTGAAGTAATATCTTTCGTAGTGGCAGAAGCATTAGAAAAAGCCCAGCTAAGTCTTGATGAAATAGATGTAATT
GCGGCTACATATGGACCAGGATTAGTTGGTGCTCTTTTAGTCGGTTTGTCATATGGTAAAGCTTTAGCGTATGCAAAAAA
TAAGCCTTTTGTAGGAGTAAATCATATAGAAGCCCACATAGCTGCAAATTACTTAGGGGGTGATTTTGCTCCTCCTTTTA
TTTGTCTTGTGGCTTCCGGTGGACATAGCCACATTGTTTTTGTAAAAAATTATGGAGAGTACGAAGTAATGGGACAGACA
ATGGACGATGCAGCAGGAGAAGCCTTTGACAAAGTAGCAAGAGCTTTGGGCTTGGGATATCCTGGAGGGCCTGCTATTGA
AAGGGCTGCAAAGCTGGGGAATATGGAAGCTATTGAGTTTCCCAAATCTTTTATGGAGGAAGGAAATTTTGATTTTAGTT
TTAGTGGGCTTAAAACAGCAGTTTTAAACTATTTAAACAGGCAAAAGCAAAAAGGAGAAGAGGTGAATATTTATGATGTG
GCGGCTAGTTTTCAAAGAAATGTGGTGGAGGTCTTGGTAAAAAAATTAATTGATGCAGCAAAGAGGAAAAATATTGGCAA
AATTTCTATAGCAGGAGGGGTAGCTTCTAATAGTTTTTTGAGGGAAAAATTAGGAGAAGAAGCGAAGAAAATTGGAATAA
GAGTCCATTATCCTGATAAAATTTATTGTACAGACAATGGGGCAATGATAGCTGCTGCCGCCTATTATGACTTTATAAAA
GGGAAAACATCTGGCTTGGATTTAAATGCCATTCCTTACTTAAAGATTGGGGAAAGAATTTGA

Upstream 100 bases:

>100_bases
TATGGCTTTAGACAATTAGGTAGAAGAAAAGGCTATTATCAAGATAATAATGAGGATGCAATTATAATGTGGAAATACGA
CTTGTGATGGTGGTGGAATA

Downstream 100 bases:

>100_bases
CTGTTGAAAATGTGGAAATCTGTCGAAGTTTATGATGTACTGCCTTTTAAGGTCTGTGGATAACTTTGTGGATATTGTGC
TTAAATATATTTCATTGTAT

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MEKDIIILGIESSCDETAAGVVKNGKEVLSNVIYSQIEIHKKYGGVVPEIASRKHIEVISFVVAEALEKAQLSLDEIDVI
AATYGPGLVGALLVGLSYGKALAYAKNKPFVGVNHIEAHIAANYLGGDFAPPFICLVASGGHSHIVFVKNYGEYEVMGQT
MDDAAGEAFDKVARALGLGYPGGPAIERAAKLGNMEAIEFPKSFMEEGNFDFSFSGLKTAVLNYLNRQKQKGEEVNIYDV
AASFQRNVVEVLVKKLIDAAKRKNIGKISIAGGVASNSFLREKLGEEAKKIGIRVHYPDKIYCTDNGAMIAAAAYYDFIK
GKTSGLDLNAIPYLKIGERI

Sequences:

>Translated_340_residues
MEKDIIILGIESSCDETAAGVVKNGKEVLSNVIYSQIEIHKKYGGVVPEIASRKHIEVISFVVAEALEKAQLSLDEIDVI
AATYGPGLVGALLVGLSYGKALAYAKNKPFVGVNHIEAHIAANYLGGDFAPPFICLVASGGHSHIVFVKNYGEYEVMGQT
MDDAAGEAFDKVARALGLGYPGGPAIERAAKLGNMEAIEFPKSFMEEGNFDFSFSGLKTAVLNYLNRQKQKGEEVNIYDV
AASFQRNVVEVLVKKLIDAAKRKNIGKISIAGGVASNSFLREKLGEEAKKIGIRVHYPDKIYCTDNGAMIAAAAYYDFIK
GKTSGLDLNAIPYLKIGERI
>Mature_340_residues
MEKDIIILGIESSCDETAAGVVKNGKEVLSNVIYSQIEIHKKYGGVVPEIASRKHIEVISFVVAEALEKAQLSLDEIDVI
AATYGPGLVGALLVGLSYGKALAYAKNKPFVGVNHIEAHIAANYLGGDFAPPFICLVASGGHSHIVFVKNYGEYEVMGQT
MDDAAGEAFDKVARALGLGYPGGPAIERAAKLGNMEAIEFPKSFMEEGNFDFSFSGLKTAVLNYLNRQKQKGEEVNIYDV
AASFQRNVVEVLVKKLIDAAKRKNIGKISIAGGVASNSFLREKLGEEAKKIGIRVHYPDKIYCTDNGAMIAAAAYYDFIK
GKTSGLDLNAIPYLKIGERI

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=327, Percent_Identity=35.474006116208, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI8923380, Length=323, Percent_Identity=32.8173374613003, Blast_Score=138, Evalue=8e-33,
Organism=Escherichia coli, GI1789445, Length=334, Percent_Identity=42.2155688622754, Blast_Score=268, Evalue=3e-73,
Organism=Caenorhabditis elegans, GI17557464, Length=322, Percent_Identity=31.3664596273292, Blast_Score=137, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI71995670, Length=316, Percent_Identity=30.379746835443, Blast_Score=112, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6320099, Length=340, Percent_Identity=30.2941176470588, Blast_Score=135, Evalue=9e-33,
Organism=Saccharomyces cerevisiae, GI6322891, Length=354, Percent_Identity=27.9661016949153, Blast_Score=102, Evalue=7e-23,
Organism=Drosophila melanogaster, GI20129063, Length=343, Percent_Identity=35.2769679300292, Blast_Score=197, Evalue=8e-51,
Organism=Drosophila melanogaster, GI21357207, Length=333, Percent_Identity=32.7327327327327, Blast_Score=137, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 36645; Mature: 36645

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00626 RCC1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKDIIILGIESSCDETAAGVVKNGKEVLSNVIYSQIEIHKKYGGVVPEIASRKHIEVIS
CCCCEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHH
FVVAEALEKAQLSLDEIDVIAATYGPGLVGALLVGLSYGKALAYAKNKPFVGVNHIEAHI
HHHHHHHHHHHCCHHHHEEEEECCCCHHHHHHHHHHHHCHHHEEECCCCCEEHHHHHHHH
AANYLGGDFAPPFICLVASGGHSHIVFVKNYGEYEVMGQTMDDAAGEAFDKVARALGLGY
HHHHCCCCCCCCEEEEEECCCCEEEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHCCCC
PGGPAIERAAKLGNMEAIEFPKSFMEEGNFDFSFSGLKTAVLNYLNRQKQKGEEVNIYDV
CCCHHHHHHHHHCCCHHHHCCHHHHHCCCCCEEHHHHHHHHHHHHHHHHHCCCCCEEEHH
AASFQRNVVEVLVKKLIDAAKRKNIGKISIAGGVASNSFLREKLGEEAKKIGIRVHYPDK
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCEEEECCCE
IYCTDNGAMIAAAAYYDFIKGKTSGLDLNAIPYLKIGERI
EEECCCCCEEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MEKDIIILGIESSCDETAAGVVKNGKEVLSNVIYSQIEIHKKYGGVVPEIASRKHIEVIS
CCCCEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHH
FVVAEALEKAQLSLDEIDVIAATYGPGLVGALLVGLSYGKALAYAKNKPFVGVNHIEAHI
HHHHHHHHHHHCCHHHHEEEEECCCCHHHHHHHHHHHHCHHHEEECCCCCEEHHHHHHHH
AANYLGGDFAPPFICLVASGGHSHIVFVKNYGEYEVMGQTMDDAAGEAFDKVARALGLGY
HHHHCCCCCCCCEEEEEECCCCEEEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHCCCC
PGGPAIERAAKLGNMEAIEFPKSFMEEGNFDFSFSGLKTAVLNYLNRQKQKGEEVNIYDV
CCCHHHHHHHHHCCCHHHHCCHHHHHCCCCCEEHHHHHHHHHHHHHHHHHCCCCCEEEHH
AASFQRNVVEVLVKKLIDAAKRKNIGKISIAGGVASNSFLREKLGEEAKKIGIRVHYPDK
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCEEEECCCE
IYCTDNGAMIAAAAYYDFIKGKTSGLDLNAIPYLKIGERI
EEECCCCCEEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]