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The map label for this gene is hyuA [H]

Identifier: 167039083

GI number: 167039083

Start: 437196

End: 439343

Strand: Direct

Name: hyuA [H]

Synonym: Teth514_0422

Alternate gene names: 167039083

Gene position: 437196-439343 (Clockwise)

Preceding gene: 167039082

Following gene: 167039084

Centisome position: 17.79

GC content: 36.17

Gene sequence:

>2148_bases
ATGTTGAAAGTAAGAATCGGTATAGATGTTGGAGGAACATTCACAGATGCGGTTGCCATAGATAATGACACTTATGAATT
AATAGGGACAGTAAAGCTTCCCACAACTCATACTGCAAAAGAGGGAGTCGCGAAAGGCATTATTGATGTACTTAAAAAAC
TTATGGATGAGTACGACATTAAGCCAGGAGATATCTTGTTTATAGCTCATGGTACAACACAGGCAACAAATGCATTATTA
GAAGGTGATGTTGTTCCTGTTGGCATTATAGCTGCAGGGAGGGGGATTGAAGGTATTAAAGTAAAAAGCGATACAAATAT
ACAAGATATAGAACTTGCACCAGGTAAAATATTAAAGATTGTAAATAAATATGTTGAATTAGACGACGAATTTGAAAAAA
ACGTAGAAATGAAAATCGAAGAGTTAAAGACGCAAGAGATAGGAGCAGTTGTTGCTGCTCAAGCCTTTTCAGTGGACGAT
CCAACAACAGAGAATAGAATAATAGAGATTGTAGAACAAAAAGGACTTCCGGTGACAGCAACGCACGAAATAACAAAGCT
ATACGGATTAAAAATAAGGACAAGGACCGCAGCAATAAACGCATGCATACTTCCCAAAATGATAGAAACAGCAAACATGA
CAGAAGAAAGCGTAAAGAAATCCGGCATAAAGGCACCTCTTATGATAATGAGAGGTGACGGAGGAGTAATGAGTATAGCA
GAAGTGAGAAAAAGACCAATACTTACCTTGCTTTCAGGACCTGCTGCAGGTGTAGCGGGTGCCCTTATGTATGAAAAAAT
ATCTGATGGCATATTCCTTGAAGTTGGAGGAACAAGTACAGATATCTCTGCAATAAAAACAGGCAAAGTAATGGTAAACT
ATGCGGAAATTGGAGGGCATAAAACATATCTTAATTCTCTTGACGTAAGAACGGTAGGAATAGCAGGGGGAAGTATGATA
AGGCTTGGTGACAAAGATATAGAAGACGTTGGACCCAGAAGTGCTCATATTGCAAATTTACCTTATGCAGTCTACAGCGA
TCCAGAAGAAATAATAGAACCTGAAATAGTATATATAAAACCAAAAAAGAACGATCCTGATAATTATGTTGCAATCAAAA
GCAAGAATGGAAAAGTATTTGCAGTAACTGTATCCTGTGCAGCAAACGTATTAGGATATGTAAGACCAGAAGATTATGCC
TATGGTAATGTAGAAGCTGCAAGAAGGGCCTTAGAACCAATTGCGAAAAAACTTAATAAAACAGTTGAAGAAGTAGCAAA
GAAAATTATGGACATTGCGAGCATGAAAGTAATAAAAGTTGTTGAACAACTTCTTACTGATTACAAACTTGACAAATCTA
CTACAGTACTTGTAGGTGGGGGAGGAGGAAGTGCATCAATAGTTCCCTATGTTGCAAAAATGATGGGTATGGACCATAGA
ATAGCCAAAAACGCCCAGGTGATCTCTACAATAGGTGTAGCACTTGCAATGGTAAGAGAAATAGTAGAGCGTACCATACA
AAATCCTACTGAAAAAGACATATTGTCAATAAGAAACGAAGCAAAAGAAGCAGTGATAAAATCGGGAGCATTAGAGGAAA
CAGTAGAAATATATGTAGAAATAGACTCACAGAAAAATATAGTGAGGGCAATTGCGACAGGAGCTACAGAGTTGCGTTCG
AAGGACATATTAAACAGGAATTTAGGACGAGAAGAAATAAAGAAAATAGCAGCTCAATCAATGAAGCTCGAGTCAGCAAA
AAACGTTCAAATAATCGATGAAACAGGTTCAATGTATATCGTAAAAGGCATAGAAAACAAGAAGAAATTTTTTGGATTGT
TATCACAAAAAATAGAAAGCGTAATGGTAATAGACAAAGAAGGAGTTATAAGACTTAACAAAAATAACGGTAAAGTATAT
AGAACAAATATAACAAACTTTGAAAATTATTTAAACAAAGCATTAGAACAAAACATATTTTACGGTGATGGTGGAGCTGA
AATTCCTGACTGCTTTATCATACTACCAAATAGAATAGTAGACTTATCAGGACTTATTGACAAAGAACAAATAATTTCAC
TGGCGAAGGTAGAAATAGGCGGTTTATCTGATAATGACCGGATACTCATATTATTAAGTAAAAGGTGA

Upstream 100 bases:

>100_bases
TGTTGTTACAGGCAACAACCCAGAACAAGTAGAAAAAGCTACAAGTGAATACAGAAAAGCTATTAACAGGCTTTAGTATA
ATTTCCATAAGGAGGAGATA

Downstream 100 bases:

>100_bases
TGAAATGATACCATCTGTATTTCTTGATAAACAACAATTAATTAGCCAGGAGTTAAAATTTGATATTTATTACAATAGGA
TATCTGAACTTAATCTTAAT

Product: hydantoinase/oxoprolinase

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 715; Mature: 715

Protein sequence:

>715_residues
MLKVRIGIDVGGTFTDAVAIDNDTYELIGTVKLPTTHTAKEGVAKGIIDVLKKLMDEYDIKPGDILFIAHGTTQATNALL
EGDVVPVGIIAAGRGIEGIKVKSDTNIQDIELAPGKILKIVNKYVELDDEFEKNVEMKIEELKTQEIGAVVAAQAFSVDD
PTTENRIIEIVEQKGLPVTATHEITKLYGLKIRTRTAAINACILPKMIETANMTEESVKKSGIKAPLMIMRGDGGVMSIA
EVRKRPILTLLSGPAAGVAGALMYEKISDGIFLEVGGTSTDISAIKTGKVMVNYAEIGGHKTYLNSLDVRTVGIAGGSMI
RLGDKDIEDVGPRSAHIANLPYAVYSDPEEIIEPEIVYIKPKKNDPDNYVAIKSKNGKVFAVTVSCAANVLGYVRPEDYA
YGNVEAARRALEPIAKKLNKTVEEVAKKIMDIASMKVIKVVEQLLTDYKLDKSTTVLVGGGGGSASIVPYVAKMMGMDHR
IAKNAQVISTIGVALAMVREIVERTIQNPTEKDILSIRNEAKEAVIKSGALEETVEIYVEIDSQKNIVRAIATGATELRS
KDILNRNLGREEIKKIAAQSMKLESAKNVQIIDETGSMYIVKGIENKKKFFGLLSQKIESVMVIDKEGVIRLNKNNGKVY
RTNITNFENYLNKALEQNIFYGDGGAEIPDCFIILPNRIVDLSGLIDKEQIISLAKVEIGGLSDNDRILILLSKR

Sequences:

>Translated_715_residues
MLKVRIGIDVGGTFTDAVAIDNDTYELIGTVKLPTTHTAKEGVAKGIIDVLKKLMDEYDIKPGDILFIAHGTTQATNALL
EGDVVPVGIIAAGRGIEGIKVKSDTNIQDIELAPGKILKIVNKYVELDDEFEKNVEMKIEELKTQEIGAVVAAQAFSVDD
PTTENRIIEIVEQKGLPVTATHEITKLYGLKIRTRTAAINACILPKMIETANMTEESVKKSGIKAPLMIMRGDGGVMSIA
EVRKRPILTLLSGPAAGVAGALMYEKISDGIFLEVGGTSTDISAIKTGKVMVNYAEIGGHKTYLNSLDVRTVGIAGGSMI
RLGDKDIEDVGPRSAHIANLPYAVYSDPEEIIEPEIVYIKPKKNDPDNYVAIKSKNGKVFAVTVSCAANVLGYVRPEDYA
YGNVEAARRALEPIAKKLNKTVEEVAKKIMDIASMKVIKVVEQLLTDYKLDKSTTVLVGGGGGSASIVPYVAKMMGMDHR
IAKNAQVISTIGVALAMVREIVERTIQNPTEKDILSIRNEAKEAVIKSGALEETVEIYVEIDSQKNIVRAIATGATELRS
KDILNRNLGREEIKKIAAQSMKLESAKNVQIIDETGSMYIVKGIENKKKFFGLLSQKIESVMVIDKEGVIRLNKNNGKVY
RTNITNFENYLNKALEQNIFYGDGGAEIPDCFIILPNRIVDLSGLIDKEQIISLAKVEIGGLSDNDRILILLSKR
>Mature_715_residues
MLKVRIGIDVGGTFTDAVAIDNDTYELIGTVKLPTTHTAKEGVAKGIIDVLKKLMDEYDIKPGDILFIAHGTTQATNALL
EGDVVPVGIIAAGRGIEGIKVKSDTNIQDIELAPGKILKIVNKYVELDDEFEKNVEMKIEELKTQEIGAVVAAQAFSVDD
PTTENRIIEIVEQKGLPVTATHEITKLYGLKIRTRTAAINACILPKMIETANMTEESVKKSGIKAPLMIMRGDGGVMSIA
EVRKRPILTLLSGPAAGVAGALMYEKISDGIFLEVGGTSTDISAIKTGKVMVNYAEIGGHKTYLNSLDVRTVGIAGGSMI
RLGDKDIEDVGPRSAHIANLPYAVYSDPEEIIEPEIVYIKPKKNDPDNYVAIKSKNGKVFAVTVSCAANVLGYVRPEDYA
YGNVEAARRALEPIAKKLNKTVEEVAKKIMDIASMKVIKVVEQLLTDYKLDKSTTVLVGGGGGSASIVPYVAKMMGMDHR
IAKNAQVISTIGVALAMVREIVERTIQNPTEKDILSIRNEAKEAVIKSGALEETVEIYVEIDSQKNIVRAIATGATELRS
KDILNRNLGREEIKKIAAQSMKLESAKNVQIIDETGSMYIVKGIENKKKFFGLLSQKIESVMVIDKEGVIRLNKNNGKVY
RTNITNFENYLNKALEQNIFYGDGGAEIPDCFIILPNRIVDLSGLIDKEQIISLAKVEIGGLSDNDRILILLSKR

Specific function: HyuA and hyuB convert D- and L-substituted hydantoins to corresponding N-carbamyl-amino acids [H]

COG id: COG0145

COG function: function code EQ; N-methylhydantoinase A/acetone carboxylase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI133901900, Length=446, Percent_Identity=27.1300448430493, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI45550492, Length=559, Percent_Identity=25.0447227191413, Blast_Score=80, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008040
- InterPro:   IPR002821 [H]

Pfam domain/function: PF05378 Hydant_A_N; PF01968 Hydantoinase_A [H]

EC number: NA

Molecular weight: Translated: 77798; Mature: 77798

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKVRIGIDVGGTFTDAVAIDNDTYELIGTVKLPTTHTAKEGVAKGIIDVLKKLMDEYDI
CEEEEEEEEECCCEECEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCC
KPGDILFIAHGTTQATNALLEGDVVPVGIIAAGRGIEGIKVKSDTNIQDIELAPGKILKI
CCCCEEEEECCCCHHHHHHHCCCCEEEEEEEECCCCCCEEEECCCCCEEEECCCHHHHHH
VNKYVELDDEFEKNVEMKIEELKTQEIGAVVAAQAFSVDDPTTENRIIEIVEQKGLPVTA
HHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHCCCCEEE
THEITKLYGLKIRTRTAAINACILPKMIETANMTEESVKKSGIKAPLMIMRGDGGVMSIA
HHHHHHHHCEEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEEEECCCCEEHHH
EVRKRPILTLLSGPAAGVAGALMYEKISDGIFLEVGGTSTDISAIKTGKVMVNYAEIGGH
HHCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCCHHEECCEEEEEEHHHCCC
KTYLNSLDVRTVGIAGGSMIRLGDKDIEDVGPRSAHIANLPYAVYSDPEEIIEPEIVYIK
CHHHCCCCEEEEEECCCCEEEECCCCHHHCCCCCCEEECCCCCEECCHHHHCCCEEEEEE
PKKNDPDNYVAIKSKNGKVFAVTVSCAANVLGYVRPEDYAYGNVEAARRALEPIAKKLNK
CCCCCCCCEEEEECCCCEEEEEEEEHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
TVEEVAKKIMDIASMKVIKVVEQLLTDYKLDKSTTVLVGGGGGSASIVPYVAKMMGMDHR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCHH
IAKNAQVISTIGVALAMVREIVERTIQNPTEKDILSIRNEAKEAVIKSGALEETVEIYVE
HHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEE
IDSQKNIVRAIATGATELRSKDILNRNLGREEIKKIAAQSMKLESAKNVQIIDETGSMYI
ECCCCHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCEEE
VKGIENKKKFFGLLSQKIESVMVIDKEGVIRLNKNNGKVYRTNITNFENYLNKALEQNIF
EECCCCHHHHHHHHHHHHCEEEEECCCCEEEEECCCCEEEEEECCHHHHHHHHHHHCCCE
YGDGGAEIPDCFIILPNRIVDLSGLIDKEQIISLAKVEIGGLSDNDRILILLSKR
ECCCCCCCCCEEEECCCCEEEHHCCCCHHHHHHHHEEEECCCCCCCEEEEEEECC
>Mature Secondary Structure
MLKVRIGIDVGGTFTDAVAIDNDTYELIGTVKLPTTHTAKEGVAKGIIDVLKKLMDEYDI
CEEEEEEEEECCCEECEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCC
KPGDILFIAHGTTQATNALLEGDVVPVGIIAAGRGIEGIKVKSDTNIQDIELAPGKILKI
CCCCEEEEECCCCHHHHHHHCCCCEEEEEEEECCCCCCEEEECCCCCEEEECCCHHHHHH
VNKYVELDDEFEKNVEMKIEELKTQEIGAVVAAQAFSVDDPTTENRIIEIVEQKGLPVTA
HHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHCCCCEEE
THEITKLYGLKIRTRTAAINACILPKMIETANMTEESVKKSGIKAPLMIMRGDGGVMSIA
HHHHHHHHCEEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEEEECCCCEEHHH
EVRKRPILTLLSGPAAGVAGALMYEKISDGIFLEVGGTSTDISAIKTGKVMVNYAEIGGH
HHCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCCHHEECCEEEEEEHHHCCC
KTYLNSLDVRTVGIAGGSMIRLGDKDIEDVGPRSAHIANLPYAVYSDPEEIIEPEIVYIK
CHHHCCCCEEEEEECCCCEEEECCCCHHHCCCCCCEEECCCCCEECCHHHHCCCEEEEEE
PKKNDPDNYVAIKSKNGKVFAVTVSCAANVLGYVRPEDYAYGNVEAARRALEPIAKKLNK
CCCCCCCCEEEEECCCCEEEEEEEEHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
TVEEVAKKIMDIASMKVIKVVEQLLTDYKLDKSTTVLVGGGGGSASIVPYVAKMMGMDHR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCHH
IAKNAQVISTIGVALAMVREIVERTIQNPTEKDILSIRNEAKEAVIKSGALEETVEIYVE
HHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEE
IDSQKNIVRAIATGATELRSKDILNRNLGREEIKKIAAQSMKLESAKNVQIIDETGSMYI
ECCCCHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCEEE
VKGIENKKKFFGLLSQKIESVMVIDKEGVIRLNKNNGKVYRTNITNFENYLNKALEQNIF
EECCCCHHHHHHHHHHHHCEEEEECCCCEEEEECCCCEEEEEECCHHHHHHHHHHHCCCE
YGDGGAEIPDCFIILPNRIVDLSGLIDKEQIISLAKVEIGGLSDNDRILILLSKR
ECCCCCCCCCEEEECCCCEEEHHCCCCHHHHHHHHEEEECCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1732229 [H]