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The map label for this gene is adcB [H]

Identifier: 167038944

GI number: 167038944

Start: 296392

End: 297186

Strand: Reverse

Name: adcB [H]

Synonym: Teth514_0276

Alternate gene names: 167038944

Gene position: 297186-296392 (Counterclockwise)

Preceding gene: 167038945

Following gene: 167038928

Centisome position: 12.09

GC content: 37.36

Gene sequence:

>795_bases
ATGATTGATATTTTTTCCTATGAATTTATGAGAAGAGCATTTATAGCCGGAAGCATTATTTCAATAATTGCACCTTTAAC
AGGTAGCTTTCTTGTCCTAAGACGGCTTTCACAAATAGGAGACACCCTTTCTCACGTTGCTTTAGCAGGAGTGGCAGCAG
GTATTTTGCTTGGAATAAATCCTACATTAGGCTCCATAATTGTGGTGCTTTTAGCTTCTTTTGGAATAGAAAAACTGAGG
AAGACATATTTCAGGTATTCCGAAATATCAATAGCCATAGTTATGTCTGCAGGAATGGCAGTAGCAATAATTCTTTTAAG
TCTTTCAAGAGGCGGCGCCGCCAACATAATGAATTATCTCTTTGGAAGTATTGTGTCTGTAACAAACACTGACGTCCTTT
TGATTTCAACTCTCGGTATCGTTGTAGTGGCGTCAATTATTTTGCTGTACAAAGAGTTATTGTACATCACCTTCGATGAA
GAAGCAGCAAAAATTTCAGGTATACCTGTAAGCTATATCAATTTCTTCTTTACAGTACTAGTAGCTTTAACTGTCGCCCT
CGCCATGAGAATTGTAGGTGCACTTTTAGTATCTTCACTAATGGTAATACCGGCTGCCGCAAGTTTAAGAATCGCCAAAA
GCTTTAAACAGACAATATTTTATGCAATACTCTTTTCCTTTATATCAGTCTTTTCGGGAATATTTCTATCCTTTTACTTA
AACTTATCCCCCGGTGGAAGTATAGTCCTCGTCTCGCTTTTTATAATGGGACTCGTTTCATTAAAGAAGAGGTAA

Upstream 100 bases:

>100_bases
GAAAAATGTGAAGCCGTCGACCTTACAGCAGGAGAATTAGCTGAAGTATATGGATATCCAGTAAAAATAGCAAAACATCA
TCACAATGGGAGTGTTAAAA

Downstream 100 bases:

>100_bases
ATAAGGAGAAAAGTAGGGGATAGTACATACTATCCCCTCAGACTGTAGACAAACTTTCGTAAAGGAGATATTCTGCATAA
GGAGCGACTTGTTACAAAGC

Product: ABC-3 protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MIDIFSYEFMRRAFIAGSIISIIAPLTGSFLVLRRLSQIGDTLSHVALAGVAAGILLGINPTLGSIIVVLLASFGIEKLR
KTYFRYSEISIAIVMSAGMAVAIILLSLSRGGAANIMNYLFGSIVSVTNTDVLLISTLGIVVVASIILLYKELLYITFDE
EAAKISGIPVSYINFFFTVLVALTVALAMRIVGALLVSSLMVIPAAASLRIAKSFKQTIFYAILFSFISVFSGIFLSFYL
NLSPGGSIVLVSLFIMGLVSLKKR

Sequences:

>Translated_264_residues
MIDIFSYEFMRRAFIAGSIISIIAPLTGSFLVLRRLSQIGDTLSHVALAGVAAGILLGINPTLGSIIVVLLASFGIEKLR
KTYFRYSEISIAIVMSAGMAVAIILLSLSRGGAANIMNYLFGSIVSVTNTDVLLISTLGIVVVASIILLYKELLYITFDE
EAAKISGIPVSYINFFFTVLVALTVALAMRIVGALLVSSLMVIPAAASLRIAKSFKQTIFYAILFSFISVFSGIFLSFYL
NLSPGGSIVLVSLFIMGLVSLKKR
>Mature_264_residues
MIDIFSYEFMRRAFIAGSIISIIAPLTGSFLVLRRLSQIGDTLSHVALAGVAAGILLGINPTLGSIIVVLLASFGIEKLR
KTYFRYSEISIAIVMSAGMAVAIILLSLSRGGAANIMNYLFGSIVSVTNTDVLLISTLGIVVVASIILLYKELLYITFDE
EAAKISGIPVSYINFFFTVLVALTVALAMRIVGALLVSSLMVIPAAASLRIAKSFKQTIFYAILFSFISVFSGIFLSFYL
NLSPGGSIVLVSLFIMGLVSLKKR

Specific function: Part of the high-affinity ABC transporter complex AdcABC involved in zinc import (Probable). Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1108

COG function: function code P; ABC-type Mn2+/Zn2+ transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-3 integral membrane protein family [H]

Homologues:

Organism=Escherichia coli, GI1788166, Length=257, Percent_Identity=31.9066147859922, Blast_Score=132, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001626 [H]

Pfam domain/function: PF00950 ABC-3 [H]

EC number: NA

Molecular weight: Translated: 28329; Mature: 28329

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDIFSYEFMRRAFIAGSIISIIAPLTGSFLVLRRLSQIGDTLSHVALAGVAAGILLGIN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PTLGSIIVVLLASFGIEKLRKTYFRYSEISIAIVMSAGMAVAIILLSLSRGGAANIMNYL
CHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
FGSIVSVTNTDVLLISTLGIVVVASIILLYKELLYITFDEEAAKISGIPVSYINFFFTVL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHCCCCHHHHHHHHHHH
VALTVALAMRIVGALLVSSLMVIPAAASLRIAKSFKQTIFYAILFSFISVFSGIFLSFYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLSPGGSIVLVSLFIMGLVSLKKR
CCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIDIFSYEFMRRAFIAGSIISIIAPLTGSFLVLRRLSQIGDTLSHVALAGVAAGILLGIN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PTLGSIIVVLLASFGIEKLRKTYFRYSEISIAIVMSAGMAVAIILLSLSRGGAANIMNYL
CHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
FGSIVSVTNTDVLLISTLGIVVVASIILLYKELLYITFDEEAAKISGIPVSYINFFFTVL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHCCCCHHHHHHHHHHH
VALTVALAMRIVGALLVSSLMVIPAAASLRIAKSFKQTIFYAILFSFISVFSGIFLSFYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLSPGGSIVLVSLFIMGLVSLKKR
CCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377 [H]