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The map label for this gene is comEB [H]

Identifier: 167038773

GI number: 167038773

Start: 97125

End: 97574

Strand: Direct

Name: comEB [H]

Synonym: Teth514_0100

Alternate gene names: 167038773

Gene position: 97125-97574 (Clockwise)

Preceding gene: 167038772

Following gene: 167038775

Centisome position: 3.95

GC content: 39.56

Gene sequence:

>450_bases
ATGAGACCCTCATGGGATGAATATTTTATGCAAATTGTAGATGTTGTAAAAACTCGCTCTACTTGTCTTAGAAGACAAGT
AGGGGCTATTTTGGTGGTGGATAAACACATAATTTCAACAGGGTATAATGGTCCTCCTACAGGACTCGCCCATTGTGAAG
AAACAGGTTGTTTGAGAGAGCAATTAGGGATACCGTCGGGAGAAAGGCCAGAGCTTTGTAGAGGTGTACATGCAGAGCAA
AATGCGATTATACAAGCAGCGTTGCATGGGGTAAGTACTAAAGGGGCTACTCTCTATGTAAGTGCCAGTCCTTGTGTCAT
ATGCGCTAAAATGTTAATCAATGCAGGAGTTAAGCGAATTGTATATGAAGAGGAGTATCCCGATGAATTAGCTTTTAAAC
TTTTAAAGGAAGCAAATATTGACTTAGTAAAAATTGAGCGACAAAAATAA

Upstream 100 bases:

>100_bases
GCATAGACCAAGGTTTAAATGAACATGGTTATATTGTACCGGGTTTAGGAGATGCAGGAGATAGGCTTTTCGGCACAAAG
TGATGGCGAGGGATGTACAA

Downstream 100 bases:

>100_bases
GCGGGGAATAAACCCCGCTTTTATAGATTTATTTTATTTATTAGCTTCTGCTTTTGTTTGACTTTTAGCGATTAGGTACC
ACAGATAACCAATTACTATT

Product: CMP/dCMP deaminase

Products: dUMP; NH3

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MRPSWDEYFMQIVDVVKTRSTCLRRQVGAILVVDKHIISTGYNGPPTGLAHCEETGCLREQLGIPSGERPELCRGVHAEQ
NAIIQAALHGVSTKGATLYVSASPCVICAKMLINAGVKRIVYEEEYPDELAFKLLKEANIDLVKIERQK

Sequences:

>Translated_149_residues
MRPSWDEYFMQIVDVVKTRSTCLRRQVGAILVVDKHIISTGYNGPPTGLAHCEETGCLREQLGIPSGERPELCRGVHAEQ
NAIIQAALHGVSTKGATLYVSASPCVICAKMLINAGVKRIVYEEEYPDELAFKLLKEANIDLVKIERQK
>Mature_149_residues
MRPSWDEYFMQIVDVVKTRSTCLRRQVGAILVVDKHIISTGYNGPPTGLAHCEETGCLREQLGIPSGERPELCRGVHAEQ
NAIIQAALHGVSTKGATLYVSASPCVICAKMLINAGVKRIVYEEEYPDELAFKLLKEANIDLVKIERQK

Specific function: Dispensable for transformability [H]

COG id: COG2131

COG function: function code F; Deoxycytidylate deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI61742819, Length=126, Percent_Identity=34.1269841269841, Blast_Score=68, Evalue=3e-12,
Organism=Homo sapiens, GI61742821, Length=126, Percent_Identity=34.1269841269841, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6321938, Length=141, Percent_Identity=40.4255319148936, Blast_Score=115, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24667298, Length=151, Percent_Identity=31.7880794701987, Blast_Score=66, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24667302, Length=151, Percent_Identity=31.7880794701987, Blast_Score=66, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR013404
- InterPro:   IPR015517
- InterPro:   IPR016193
- InterPro:   IPR016473 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: 3.5.4.12

Molecular weight: Translated: 16509; Mature: 16509

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPSWDEYFMQIVDVVKTRSTCLRRQVGAILVVDKHIISTGYNGPPTGLAHCEETGCLRE
CCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEECHHHHHCCCCCCCCCCHHHHHHHHHHH
QLGIPSGERPELCRGVHAEQNAIIQAALHGVSTKGATLYVSASPCVICAKMLINAGVKRI
HHCCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHH
VYEEEYPDELAFKLLKEANIDLVKIERQK
HCCCCCCHHHHHHHHHHCCCCEEEEECCC
>Mature Secondary Structure
MRPSWDEYFMQIVDVVKTRSTCLRRQVGAILVVDKHIISTGYNGPPTGLAHCEETGCLRE
CCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEECHHHHHCCCCCCCCCCHHHHHHHHHHH
QLGIPSGERPELCRGVHAEQNAIIQAALHGVSTKGATLYVSASPCVICAKMLINAGVKRI
HHCCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHH
VYEEEYPDELAFKLLKEANIDLVKIERQK
HCCCCCCHHHHHHHHHHCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dCMP; H2O

Specific reaction: dCMP + H2O = dUMP + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7968523; 8969508; 9384377 [H]