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The map label for this gene is tdk

Identifier: 167038764

GI number: 167038764

Start: 89913

End: 90494

Strand: Direct

Name: tdk

Synonym: Teth514_0091

Alternate gene names: 167038764

Gene position: 89913-90494 (Clockwise)

Preceding gene: 167038763

Following gene: 167038765

Centisome position: 3.66

GC content: 38.32

Gene sequence:

>582_bases
ATGATATACGGATCTTTGGATCATGGTTTTATAGAGGTTATAGTTGGTCCTATGTTTAGCGGTAAAAGTGAAGAACTAAT
AAGAAGGATTAAAAGAGCACAAATTGCCAAACAAAAAGTACAAGTTTTTAAACCGGCTATTGACGATAGATATTCTATTG
ACAAGGTGGTATCTCACAATGGCACTAATATAAATGCTATTAGTGTAGTAAAAGCTTTTGAAATAATTGAGCTTTTAGAA
GAAGACACAGAGGTTATCGCAATTGATGAAATTCAGTTTTTTGACCATTCGATTGTGGATGTTGTAAGGGAAATTGCTGA
TTTGGGCAAAAGAGTCATTTGTGCTGGCTTAGATATGGACTTTAGGGGAGAACCATTTGGGCCTACTCCTGATGTAATGG
CAATTGCGGAGTCTGTGGATAAACTGACGGCTATATGTGTGAAATGTGGCAATCCTGCTACTCGCACTCAAAGGCTTATC
AATGGGAAACCTGCAAAATACGATGATCCAATCATTTTAGTAGGGGCCCATGAAACCTATGAAGCAAGGTGTCGAAAATG
CCATGAAGTTCCCCGTACATAG

Upstream 100 bases:

>100_bases
TTAGAAAGAGATTTAATTTAGAGGAAAAATAATTTGGGGGTTAGAGTGGTGAAGACTCTAACCTTTTGTTTTTAATTTGA
CATTAAGAAAGGTGGTTTTC

Downstream 100 bases:

>100_bases
AAAAGAGGTGTAATAATGAAAAAAACTGATATAGGTGGTCAAGCAGTAATTGAAGGAGTTATGATGAGAGGACACAATAG
TGTAGCGACAGCTGTAAGAA

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MIYGSLDHGFIEVIVGPMFSGKSEELIRRIKRAQIAKQKVQVFKPAIDDRYSIDKVVSHNGTNINAISVVKAFEIIELLE
EDTEVIAIDEIQFFDHSIVDVVREIADLGKRVICAGLDMDFRGEPFGPTPDVMAIAESVDKLTAICVKCGNPATRTQRLI
NGKPAKYDDPIILVGAHETYEARCRKCHEVPRT

Sequences:

>Translated_193_residues
MIYGSLDHGFIEVIVGPMFSGKSEELIRRIKRAQIAKQKVQVFKPAIDDRYSIDKVVSHNGTNINAISVVKAFEIIELLE
EDTEVIAIDEIQFFDHSIVDVVREIADLGKRVICAGLDMDFRGEPFGPTPDVMAIAESVDKLTAICVKCGNPATRTQRLI
NGKPAKYDDPIILVGAHETYEARCRKCHEVPRT
>Mature_193_residues
MIYGSLDHGFIEVIVGPMFSGKSEELIRRIKRAQIAKQKVQVFKPAIDDRYSIDKVVSHNGTNINAISVVKAFEIIELLE
EDTEVIAIDEIQFFDHSIVDVVREIADLGKRVICAGLDMDFRGEPFGPTPDVMAIAESVDKLTAICVKCGNPATRTQRLI
NGKPAKYDDPIILVGAHETYEARCRKCHEVPRT

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family

Homologues:

Organism=Homo sapiens, GI164698438, Length=186, Percent_Identity=40.3225806451613, Blast_Score=116, Evalue=1e-26,
Organism=Escherichia coli, GI1787490, Length=177, Percent_Identity=30.5084745762712, Blast_Score=67, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17543396, Length=184, Percent_Identity=34.7826086956522, Blast_Score=103, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KITH_THEP3 (B0K7G9)

Other databases:

- EMBL:   CP000924
- RefSeq:   YP_001666071.1
- ProteinModelPortal:   B0K7G9
- SMR:   B0K7G9
- GeneID:   5874655
- GenomeReviews:   CP000924_GR
- KEGG:   tpd:Teth39_2112
- HOGENOM:   HBG522108
- OMA:   VITGPMY
- ProtClustDB:   PRK04296
- BioCyc:   TPSE340099:TETH39_2112-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00124
- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634
- PANTHER:   PTHR11441
- PIRSF:   PIRSF035805

Pfam domain/function: PF00265 TK

EC number: =2.7.1.21

Molecular weight: Translated: 21525; Mature: 21525

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: ACT_SITE 90-90

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYGSLDHGFIEVIVGPMFSGKSEELIRRIKRAQIAKQKVQVFKPAIDDRYSIDKVVSHN
CCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCC
GTNINAISVVKAFEIIELLEEDTEVIAIDEIQFFDHSIVDVVREIADLGKRVICAGLDMD
CCCCHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHCHHEEEECCCCC
FRGEPFGPTPDVMAIAESVDKLTAICVKCGNPATRTQRLINGKPAKYDDPIILVGAHETY
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCEEEEECCCHH
EARCRKCHEVPRT
HHHHHHHHCCCCC
>Mature Secondary Structure
MIYGSLDHGFIEVIVGPMFSGKSEELIRRIKRAQIAKQKVQVFKPAIDDRYSIDKVVSHN
CCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCC
GTNINAISVVKAFEIIELLEEDTEVIAIDEIQFFDHSIVDVVREIADLGKRVICAGLDMD
CCCCHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHCHHEEEECCCCC
FRGEPFGPTPDVMAIAESVDKLTAICVKCGNPATRTQRLINGKPAKYDDPIILVGAHETY
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCEEEEECCCHH
EARCRKCHEVPRT
HHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA